This study is based on the absence of a comprehensive description of the symbol of Dhammacakkappavattana Sutta (Sermon on the Dhamma Wheel) in the Mendut Monastery. This study aims to describe the holistic meaning of the symbolization of the first sermon containing the core of the Buddha's teachings, namely the Dhammacakkappavattana Sutta carved on the wooden window of the main dhammasālā at the Mendut Monastery complex.This study uses analytical methods of interpretation (understanding and interpretation) with procedures: (a) inventory of empirical data objects as simple ideas; (b) the granting and excavation of the meaning contained in the object; (c) understanding through insight; and (d) interpretation. The object material of this study is the twelve symbols of the first preaching of the Buddha, the Dhammacakkappavattana Sutta, carved in the wooden windows as a series arranged in sequence as an explanation of the content of the sermon. The validity of the study is based on a confirmability that reflects the objectivity of the study.The results of the study show that: (a) the Dhammacakkappavattana Sutta's sermon is symbolized into twelve icons or characters, namely the dharmacakra with thirty spokes (thirty-dharma wheels) and the dharmacakra with twelve spokes as an introduction, then the dharmacakra with three strings, the dharmacakra with eight spokes, the dharmacakra with four blades in which each has thick and thin sides, the dharmacakra with twenty four spokes, the dharmacakra with eight spokes, the lotus symbol, the striped circle, the eye symbol seeing waves, the single eye symbols, and the broken gongs; (b) the symbols of the Dhammacakkappavattana Sutta are understood and interpreted as a well-organized meaningful explanations reflecting the content of the sermon. They are commenced by cultivating the pāramitā (virtue) which is ten in number, each of which has three levels, the comprehension of the law of dependent origination, the two extremes namely self-mortification and self-indulgence, the Noble Eightfold Path as the middle way, the realization of the Four Noble Truths, the details of the Four Noble Truths, the Noble Eightfold Path as a path to be developed, the implementation of sīla as the basis, tranquility meditation, vipassanā meditation, the manifestation of paññā, and the attainment of Nibbāna.The consequence of the Dhammacakkappavattana Symbolization simplified into a particular icon makes it easy to understand the content of the sermon. It can be used as a medium of Dharma education which is more contextual with an easy and powerful language.