scholarly journals Hepatitis B prevention: Can we learn from the response to HIV/AIDS?

PLoS Medicine ◽  
2020 ◽  
Vol 17 (4) ◽  
pp. e1003109
Author(s):  
Mirjam E. E. Kretzschmar ◽  
Marianne A. B. van der Sande
2021 ◽  
Vol 9 (6) ◽  
pp. 1166
Author(s):  
Charlotte Bauquier ◽  
Marie Préau

Recent scientific advances in hepatitis B virus research hint at the possibility of finding a cure in the medium term. In this context, the characterization of infected persons constitutes a major public health issue in terms of implementing adapted screening and prevention strategies. Overcoming the current challenges national health systems face in hepatitis B diagnosis is essential if the World Health Organization’s target of treating 80% of infected patients by 2030 is to be reached. These challenges reflect those previously faced in the fight against HIV/AIDS. Using the knowledge produced to date in Human and Social Sciences research in the fight against HIV/AIDS, we propose avenues of reflection to support and guide the development of research in the diagnosis of hepatitis B infection. More specifically, we present theoretical, methodological and epistemological considerations for how HSS research can be optimized in the following three HBV diagnosis-related areas: (i) access to screening; (ii) retention in care; and (iii) the integration of quality of life measurement in clinical trials.


2019 ◽  
Vol 14 (12) ◽  
pp. 791-798
Author(s):  
Ivailo Alexiev ◽  
Elitsa Golkocheva-Markova ◽  
Asya Kostadinova ◽  
Reneta Dimitrova ◽  
Lora Nikolova ◽  
...  

Aim: To evaluate hepatitis B virus (HBV) and hepatitis C virus (HCV) among individuals with HIV/AIDS in Bulgaria diagnosed between 2010 and 2015. Materials & methods: A total of 1158 individuals were diagnosed with HIV/AIDS during the study period. Different transmission groups were tested with ELISA and real-time PCR for HBV and HCV markers. Results: Hepatitis B surface antigen and hepatitis C virus antiboby were found in 9.3 and 23.2% of the tested. HBV DNA and HCV RNA has been found in 47.4 and 69.6%. Hepatitis B and C co-infections were predominant in multiple risk behavior groups, including people who inject drugs, men who have sex with men, prisoners and Roma individuals. Conclusion: HIV prevalence in Bulgaria is low but the rates of hepatitis B and C co-infections among these patients fall within the upper range reported in Europe.


1986 ◽  
Vol 2 (5) ◽  
pp. 290-296
Author(s):  
Kenneth E. Sherman ◽  
Susan N. Sherman ◽  
William P. Ku ◽  
Barbara Stewart ◽  
Gail J. Povar

1986 ◽  
Vol 7 (2) ◽  
pp. 74-77 ◽  
Author(s):  
William M. Valenti

Since the introduction of hepatitis B immune globulin (HBIg) and more recently, the hepatitis B vaccine, programs for hepatitis B prevention have become a major part of most employee health/infection control programs. In fact, hepatitis B prevention activities have probably been responsible for increased collaboration between the two programs. Hepatitis B prevention is a very fluid process and is constantly changing as we develop a greater understanding of the creative uses of both HBIg and the vaccine. On e important trend that has emerged from the introduction and widespread use of HBIg and vaccine has been a greater emphasis on pre-exposure prevention of hepatitis B infection. In the past, programs for hepatitis B prevention consisted of periodic hepatitis B screening in dialysis units and some laboratories. Unfortunately, screening only monitors introduction of infection and does very little to prevent hepatitis B virus (HBV) infection.


2014 ◽  
Vol 30 (2) ◽  
pp. 433-438 ◽  
Author(s):  
Silvano Barbosa de Oliveira ◽  
Edgar Merchan-Hamann ◽  
Leila Denise Alves Ferreira Amorim

The aim of this study is to estimate the prevalence of HIV/HBV and HIV/HCV coinfections among AIDS cases reported in Brazil, and to describe the epidemiological profile of these cases. Coinfection was identified through probabilistic record linkage of the data of all patients carrying the HIV virus recorded as AIDS patients and of those patients reported as carriers of hepatitis B or C virus in various databases from the Brazilian Ministry of Health from 1999 to 2010. In this period 370,672 AIDS cases were reported, of which 3,724 were HIV/HBV coinfections. Women are less likely to become coinfected than men and the chance of coinfection increases with age. This study allowed an important evaluation of HBV/HIV and HCV/HIV coinfections in Brazil using information obtained via merging secondary databases from the Ministry of Health, without conducting seroprevalence research. The findings of this study might be important for planning activities of the Brazilian epidemiologic surveillance agencies.


2019 ◽  
Vol 5 (4) ◽  
pp. 247-256
Author(s):  
Najibeh Mirzazadeh ◽  
◽  
Leila Amini ◽  
Seyed Moayed Alavian ◽  
Hamid Haghani ◽  
...  

Background: Unawareness and inappropriate attitude toward hepatitis B can expose healthy people, especially immigrants, to a higher risk of hepatitis B transmission. The present study aimed to determine the effect of hepatitis B prevention education by face-to-face and distance training on the knowledge and attitude of Afghan immigrant students. Methods: This randomized controlled trial was conducted on 128 voluntary immigrant nonmedical Afghan students of Imam Khomeini University in Qazvin City, Iran. The study subjects were randomly assigned to 4 groups (A1, A2, B1, & B2), and the training was performed using Solomon’s four-group-design. The A groups received face-to-face education, while the B groups received distance education through email and Telegram messenger. The required data were collected using a self-structured questionnaire at three-time intervals of before, immediately after, and one month after training. The collected data were analyzed by the Chi-squared test, Independent Samples t-test, Paired Samples t-test, and repeated-measures Analysis of Variance (ANOVA) using SPSS. Results: Based on the study findings, the improvement of knowledge and attitude values was more significant in the face-to-face groups, compared to the distance education groups. However, there was a significant difference in both methods (P<0.001). Conclusion: Although knowledge improvement was higher in the face-to-face education groups, there was also an increase in the knowledge and attitude of the distance education group. Therefore, face-to-face education is preferred; however, using a combination of these educational methods could be beneficial.


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