Abstract
Background and Aims: There are studies that show NC measurements are associated with central obesity and upper body fat distribution and are strongly associated with metabolic markers. Recently, studies have been conducted regarding neck circumference (NC) as a novel index to screen for obesity and cardiometabolic risk factors. Here, we investigated various anthropometric measurements and their correlations with cardiometabolic risk factors, pulmonary function test (PFT) results and metabolic syndrome among the adult Korean population. Methods: This study was based on data acquired from the 8th edition (2019) of the Korea National Health and Nutrition Examination Survey (KNHANES), consisting of survey data on smoking and alcohol consumption, cardiometabolic risk factors, PFT results, metabolic syndrome profile and baseline characteristics such as age, gender and blood pressure. Continuous variables were analyzed by independent t-test, while categorical variables were analyzed using the Rao-Scott chi-square test Precision-recall (PR) plots were used to assess the diagnostic value of anthropometric measurements for cardiometabolic risk profiles such as insulin resistance, impaired glucose tolerance, dyslipidemia, hypertension, central obesity and PFT results. Area under the curve (AUC) was used to evaluate the predictive ability of the anthropometric measurements and calculation-modified anthropometric measurements (CMAMs) such as NC(neck circumference) devided by BMI(body mass index) and WC(waist circumference) and BMI devided by WC at different preset thresholds. Calculation was used to distinguish each anthropometric measurements aside from common features they may share. Results: A total of 3525study subjects aged over 40 years were included in the study the mean age for male and female were 56.8 and 58.5 respectively, percentage of male and female was 42% and 58% respectively. PR plots of anthropometric measurements and the metabolic syndrome profile indicated that in the presence of 3 metabolic syndrome criteria, waist circumference (WC) and body mass index (BMI) had the highest AUCs 0.62 and 0.587 respectively, in the presence of 4 metabolic syndrome criteria, waist circumference (WC) and body mass index (BMI) had the highest AUCs 0.342 and 0.317 respectively whereas in the presence of more than 5 metabolic syndrome criteria, NC and WC had the highest AUCs 0.09 and 0.083 respectively.Conclusion: This study showed that NC is correlated with metabolic syndrome. Additionally, each anthropometric measurement was uniquely correlated with specific cardiometabolic risk factor and differed according to sex. In such cases, applications in smartphones could be used to calculate for cardiometabolic risk assessments. Also it may be necessary to screen for metabolic syndrome in people whose NC is over 39.9cm for males and 34.5cm for females.