scholarly journals Influence of Anodal Transcranial Direct Current Stimulation (tDCS) over the Right Angular Gyrus on Brain Activity during Rest

PLoS ONE ◽  
2014 ◽  
Vol 9 (4) ◽  
pp. e95984 ◽  
Author(s):  
Benjamin Clemens ◽  
Stefanie Jung ◽  
Gianluca Mingoia ◽  
David Weyer ◽  
Frank Domahs ◽  
...  
Keyword(s):  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Brain Activity ◽  
Angular Gyrus ◽  
Direct Current Stimulation ◽  
The Right

scholarly journals Transcranial Direct Current Stimulation Combining Mindfulness-Based Relapse Prevention for Smoking Cessation: A Case Report

2019 ◽  
Vol 6 (3) ◽  
pp. 118-122
Author(s):  
Zahra Khayyer ◽  
Razieh Saberi Azad ◽  
Mohsen Dadjoo ◽  
Azam Shojaei
Keyword(s):  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Relapse Prevention ◽  
Brain Activity ◽  
Substantial Reduction ◽  
Central Zone ◽  
Efficient Treatment ◽  
Direct Current Stimulation ◽  
Anodal Stimulation ◽  
The Right

Previous electroencephalography (EEG) researches have shown significant differences in terms of abnormal brain activity among smokers and non-smokers. Typically, EEG analysis showed decreased slow waves and increased fast waves in people with nicotine consumption. The present study tested a transcranial direct current stimulation (tDCS) technique combined with Mindfulness-based relapse prevention (MBRP) to reduce nicotine cravings. Specifically, cathodal tDCS over left prefrontal cortex (PFC), as well as anodal stimulation over the right central zone, tested. An 18-year-old right-handed male with almost 3 years of smoking participated. He had no anti-tobacco medical prescription. The participant received twelve sessions of tDCS treatment (2 times a week). Anodal stimulation (1.5 mA, 15 minutes) performed on C3 (LORETA source localization) and cathodal stimulation on FP2. Also, the participant received 30-minute MBRP-based psychotherapy sessions in order to ameliorate aggression, stress, and craving. Clinical evaluations, Buss-Perry Aggression Questionnaire (AGQ), Fagerstrom Test for Nicotine Dependence (FTND), Perceived Stress Scale (Cohen, Kamarck, & Mermelstein, 1994), and daily checklist for the number of smoked cigarettes administered along with carbon monoxide (CO) levels. Also, subjective measures of craving intensity between zero and ten measured after treatment and 3-month follow-up. After treatment, the participant showed a substantial reduction in all clinical tests, and the number of cigarettes decreased from 30 to 2 a day. From a psycho neurotherapeutic perspective, the present study provides preliminary indications for a novel and efficient treatment of smoking during adolescence. Further studies are needed to determine generalizability and overall efficiency.

scholarly journals Comparison of repeated transcranial stimulation and transcranial direct-current stimulation on primary motor cortex excitability and inhibition: A pilot study

2018 ◽  
pp. 59-67 ◽  
Author(s):  
Vincent Cabibel ◽  
Makii Muthalib ◽  
Jérôme Froger ◽  
Stéphane Perrey
Keyword(s):  
Pilot Study ◽  
Motor Cortex ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Primary Motor Cortex ◽  
Motor Evoked Potentials ◽  
High Definition ◽  
Direct Current Stimulation ◽  
Motor Cortex Excitability ◽  
The Right

Repeated transcranial magnetic stimulation (rTMS) is a well-known clinical neuromodulation technique, but transcranial direct-current stimulation (tDCS) is rapidly growing interest for neurorehabilitation applications. Both methods (contralesional hemisphere inhibitory low-frequency: LF-rTMS or lesional hemisphere excitatory anodal: a-tDCS) have been employed to modify the interhemispheric imbalance following stroke. The aim of this pilot study was to compare aHD-tDCS (anodal high-definition tDCS) of the left M1 (2 mA, 20 min) and LF-rTMS of the right M1 (1 Hz, 20 min) to enhance excitability and reduce inhibition of the left primary motor cortex (M1) in five healthy subjects. Single-pulse TMS was used to elicit resting and active (low level muscle contraction, 5% of maximal electromyographic signal) motor-evoked potentials (MEPs) and cortical silent periods (CSPs) from the right and left extensor carpi radialis muscles at Baseline, immediately and 20 min (Post-Stim-20) after the end of each stimulation protocol. LF-rTMS or aHD-tDCS significantly increased right M1 resting and active MEP amplitude at Post-Stim-20 without any CSP modulation and with no difference between methods. In conclusion, this pilot study reported unexpected M1 excitability changes, which most likely stems from variability, which is a major concern in the field to consider.

scholarly journals Exploring the neural, behavioural, and clinical effects of transcranial direct current stimulation in patients with a Prolonged Disorder of Consciousness; protocol for a double-blind randomised crossover feasibility study

2020 ◽  
Author(s):  
Davinia Fernández-Espejo ◽  
Davide Aloi ◽  
Antonio Incisa della Rocchetta ◽  
Damon Hoad ◽  
Richard Greenwood ◽  
...  
Keyword(s):  
Individual Differences ◽  
Feasibility Study ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Brain Activity ◽  
Brain Structures ◽  
Clinical Effects ◽  
Disorder Of Consciousness ◽  
Double Blind ◽  
Direct Current Stimulation

Abstract Background: Therapeutic options for patients with prolonged disorders of consciousness (PDOC) are very limited, and patients often show little to no progress over time. It is widely recognized that some PDOC patients retain a higher level of cognition that may be apparent on the basis of their external responses, and simply are unable to produce purposeful motor behaviours. This dissociation has been linked to specific impairments in the motor network that lead to a reduction in thalamo-cortical coupling. Here, we will assess whether transcranial direct current stimulation (tDCS) can modulate thalamo-cortical coupling and improve patients’ responsiveness. We will focus on characterising the mechanisms of action of tDCS and the bases for potential individual differences in responsiveness to the stimulation across participants.Methods: This is a multi-centre double-blind randomised crossover feasibility study. It is divided into two streams: (a) MRI stream: 5 PDOC patients will complete 5 anodal, cathodal, and sham stimulation sessions (paired with passive mobilisation of the thumb) in separate weeks. We will measure brain activity and connectivity with functional magnetic resonance imaging and electroencephalography (EEG). We will look at brain structures to assess differences associated with responsiveness. (b) Bedside stream: 10 patients will complete one session of anodal or cathodal stimulation and one session of sham. We will measure brain activity and connectivity with EEG and we will conduct follow up assessments at 3 and 6 months. In both streams we will also look at changes in the clinical profile of patients with the Coma Recovery Scale Revised and in command following behaviour with electromyography and motion tracking. We will assess feasibility on measures of eligibility, recruitment, retention, and completion of tests.Discussion: This feasibility study is the first step towards developing personalised tDCS interventions to restore external responsiveness in PDOC patients. Our results will inform the design of a future trial fully powered for characterising neural, behavioural, and clinical effects of tDCS in PDOC as well as the mechanisms underlying individual differences in responsiveness.

scholarly journals Transcranial Direct Current Stimulation to Facilitate Lower Limb Recovery Following Stroke: Current Evidence and Future Directions

2020 ◽  
Vol 10 (5) ◽  
pp. 310
Author(s):  
Samuel Gowan ◽  
Brenton Hordacre
Keyword(s):  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Lower Limb ◽  
Cortical Neurons ◽  
Brain Activity ◽  
Current Evidence ◽  
Potential Candidate ◽  
Limb Function ◽  
Direct Current Stimulation ◽  
Lower Limb Function

Stroke remains a global leading cause of disability. Novel treatment approaches are required to alleviate impairment and promote greater functional recovery. One potential candidate is transcranial direct current stimulation (tDCS), which is thought to non-invasively promote neuroplasticity within the human cortex by transiently altering the resting membrane potential of cortical neurons. To date, much work involving tDCS has focused on upper limb recovery following stroke. However, lower limb rehabilitation is important for regaining mobility, balance, and independence and could equally benefit from tDCS. The purpose of this review is to discuss tDCS as a technique to modulate brain activity and promote recovery of lower limb function following stroke. Preliminary evidence from both healthy adults and stroke survivors indicates that tDCS is a promising intervention to support recovery of lower limb function. Studies provide some indication of both behavioral and physiological changes in brain activity following tDCS. However, much work still remains to be performed to demonstrate the clinical potential of this neuromodulatory intervention. Future studies should consider treatment targets based on individual lesion characteristics, stage of recovery (acute vs. chronic), and residual white matter integrity while accounting for known determinants and biomarkers of tDCS response.

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