Risk Factors for Long-Term Mortality after Hospitalization for Community-Acquired Pneumonia: A 5-Year Prospective Follow-Up Study

Aims: This study aimed to assess risk factors of intradialytic hypotension (IDH) and the association of prognosis and IDH among maintenance hemodialysis (MHD) patients. Methods: Among 293 patients, 117 were identified with IDH (more than 4 hypotensive events during 3 months). The association between IDH and survival was evaluated. Results: The incidence of IDH was 39.9%. Age, ultrafiltration rate, N-terminal pro-B-type natriuretic peptide (NT-proBNP), albumin, β2-microglobulin (β2MG), and aortic root inside diameter (AoRD) were independently associated with IDH. During the 5-year follow-up, 84 patients died with a mortality rate 5.2 per 100 person-year. IDH-prone patients had a higher all-cause mortality rate. IDH and left ventricular mass index were independent risk factors for death (HR 1.655, 95% CI 1.061–2.580; HR 1.008, 95% CI 1.001–1.016). Conclusion: IDH is an independent risk factor for long-term mortality in MHD patients. Patients with older age, high ultrafiltration rate, high level of serum NT-proBNP and β2MG, hypoalbuminemia, and shorter AoRD are at high risk of IDH.

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Long-term mortality following peptic ulcer perforation in the PULP trial. A nationwide follow-up study

Scandinavian Journal of Gastroenterology ◽

10.3109/00365521.2012.746393 ◽

2012 ◽

Vol 48 (2) ◽

pp. 168-175 ◽

Cited By ~ 13

Author(s):

Morten Hylander Møller ◽

Morten Vester-Andersen ◽

Reimar Wernich Thomsen

Keyword(s):

Peptic Ulcer ◽

Peptic Ulcer Perforation ◽

Ulcer Perforation ◽

Follow Up Study ◽

Long Term Mortality

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Differences in mortality and suicidal behaviour between treated and never-treated people with schizophrenia in rural China

The British Journal of Psychiatry ◽

10.1192/bjp.bp.108.055301 ◽

2009 ◽

Vol 195 (2) ◽

pp. 126-131 ◽

Cited By ~ 28

Author(s):

Mao-Sheng Ran ◽

Cecilia Lai-Wan Chan ◽

Eric Yu-Hai Chen ◽

Wen-Jun Mao ◽

Shi-Hui Hu ◽

...

Keyword(s):

Suicidal Behaviour ◽

Rural China ◽

Middle Income ◽

Follow Up Study ◽

Duration Of Illness ◽

All Cause Mortality ◽

Mortality Ratio ◽

Long Term Mortality

BackgroundMany people with schizophrenia remain untreated in the community. Long-term mortality and suicidal behaviour among never-treated individuals with schizophrenia in the community are unknown.AimsTo explore 10-year mortality and suicidal behaviour among never-treated individuals with schizophrenia.MethodWe used data from a 10-year prospective follow-up study (1994–2004) among people with schizophrenia in Xinjin County, Chengdu, China.ResultsThe mortality rate for never-treated individuals with schizophrenia was 2761 per 100 000 person-years during follow-up. There were no significant differences of rates of suicide and all-cause mortality between never-treated and treated individuals. The standardised mortality ratio (SMR) for never-treated people was 10.4 (95% CI 7.2–15.2) and for treated individuals 6.5 (95% CI 5.2–8.5). Compared with treated people, never-treated individuals were more likely to be older, poorer, have a longer duration of illness, marked symptoms and fewer family members.ConclusionsThe never-treated individuals have similar mortality to and a higher proportion of marked symptoms than treated people, which may reflect the poor outcome of the individuals without treatment. The higher rates of mortality, homelessness and never being treated among people with schizophrenia in low- and middle-income nations might challenge presumed wisdom about schizophrenia outcomes in these countries.

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A Long-term Follow-up Study on Risk Factors for Hepatocellular Carcinoma among Japanese Patients with Liver Cirrhosis

Japanese Journal of Cancer Research ◽

10.1111/j.1349-7006.1998.tb00520.x ◽

1998 ◽

Vol 89 (12) ◽

pp. 1241-1250 ◽

Cited By ~ 26

Author(s):

Keitaro Tanaka ◽

Hironori Sakai ◽

Makoto Hashizume ◽

Tomio Hirohata

Keyword(s):

Risk Factors ◽

Hepatocellular Carcinoma ◽

Liver Cirrhosis ◽

Japanese Patients ◽

Follow Up Study ◽

Long Term Follow Up

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Progression of vertebral fractures in long-term controlled acromegaly: a 9-year follow-up study

Acta Endocrinologica ◽

10.1530/eje-20-0415 ◽

2020 ◽

Vol 183 (4) ◽

pp. 427-437 ◽

Cited By ~ 2

Author(s):

I C M Pelsma ◽

N R Biermasz ◽

A M Pereira ◽

W R van Furth ◽

N M Appelman-Dijkstra ◽

...

Keyword(s):

Risk Factors ◽

Growth Hormone ◽

Vertebral Fracture ◽

Follow Up Study ◽

Total Incidence ◽

Point Increase ◽

Associated Risk Factors ◽

Spine Radiographs

Objective: Growth hormone (GH) and insulin-like growth factor 1 (IGF-1) excess results in both reversible and irreversible musculoskeletal damage, including increased vertebral fracture (VF) risk. The prevalence of VFs is approximately 60% in controlled acromegaly patients, and these VFs can progress in time. We aimed to identify the course of VFs in a cohort of acromegaly patients in long-term remission and their associated risk factors during prolonged follow-up. Methods: Thirty-one patients with acromegaly (49% female, median age 60 years (IQR 53–66)), who were in remission for ≥2 years, were included in this longitudinal, prospective, follow-up study. Spine radiographs of vertebrae Th4 to L4 were assessed for VFs using the Genant score, at baseline, after 2.6 years and 9.1 years. Progression was defined as either a new fracture or a ≥1-point increase in Genant score. Results: The prevalence of VF at baseline was 87% (27/31 patients). Progression of VFs was observed in eleven patients (35.5%) during the 9.1-year follow-up period, with a total incidence rate of 65.5 per 1000 person years (males 59.8 per 1000 person years vs females 71.6 per 1000 person years). Patients treated with surgery or radiotherapy had a higher risk of VF progression in this cohort (P = 0.030). Conclusions: In this cohort of long-term, well-controlled acromegalic patients, the prevalence and progression of VFs was high, showing that the deleterious effects of GH and IGF-1 excess on bone persist despite achievement of longstanding remission.

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