scholarly journals Developmental shape changes in facial morphology: Geometric morphometric analyses based on a prospective, population-based, Chinese cohort in Hong Kong

PLoS ONE ◽  
2019 ◽  
Vol 14 (6) ◽  
pp. e0218542 ◽  
Author(s):  
Yi Feng Wen ◽  
Hai Ming Wong ◽  
Colman P. McGrath
2018 ◽  
Vol 3 (1) ◽  

Facial investigations using geometric morphometrics has been used in many studies to affirm that a particular disease can attribute to an individual’s facial morphology. A landmark based geometric morphometric analysis was used in this study to asses if facial shape changes are associated with cardiovascular diseases (CVD) and if facial morphology of the CVD individuals differs from the normal ones. In the Municipality of Cantilan, Surigao del Sur, frontal face images taken from 32 cardiovascular disease patients and 32 normal individuals were examined using forty-one manually positioned landmarks. Result showed that facial morphology of the CVD group differs from non-CVD group. Procrustes ANOVA showed significant values for the individual symmetry and directional asymmetry. The analysis of structure by the Principal Components reveals particular variations and the scatter plot of the residual asymmetry shows distinct differences between CVD and non-CVD. Therefore, cardiovascular diseases contribute to facial shape changes and that development of facial morphology differs between CVD and non-CVD group.


2016 ◽  
Vol 79 (2) ◽  
pp. 181-200 ◽  
Author(s):  
Marie Jandová ◽  
Petra Urbanová

Abstract Background and aim: The effect of socio-economic factors (living conditions) and parental smoking habits on development of facial morphology and body measurements was studied on a longitudinal Czech sample of 25 girls and 25 boys. Subjects and methods: A set of studied digitalized photographs taken from 0.5 to 18 years in intervals of 6 months originated in the Brno Longitudinal Study. Facial shape changes of sub-adult participants were described using a configuration of 27 landmarks and further studied by using methods of geometric morphometric and multivariate statistics. In order to localize growth-related shape changes within the face, the studied region was divided into upper, middle and lower facial units and analyzed separately. Results and conclusion: The results show that in the course of ontogenesis there is a strong correlation between facial shape change and body measurements, height included (r=0.10 and r=0.24 in boys and in girls, respectively). The pubertal spurt of the facial shape change rate was revealed at 10.5 years in girls and at 11.5 years in boys. The earlier onset of the pubertal rate increase in facial shape changes in boys was associated with records of poor living conditions. In addition, the mother’s smoking habits were linked to a noticeable facial shape change.


2021 ◽  
pp. 1-25
Author(s):  
Qionggui Zhou ◽  
Xuejiao Liu ◽  
Yang Zhao ◽  
Pei Qin ◽  
Yongcheng Ren ◽  
...  

Abstract Objective: The impact of baseline hypertension status on the BMI–mortality association is still unclear. We aimed to examine the moderation effect of hypertension on the BMI–mortality association using a rural Chinese cohort. Design: In this cohort study, we investigated the incident of mortality according to different BMI categories by hypertension status. Setting: Longitudinal population-based cohort Participants: 17,262 adults ≥18 years were recruited from July to August of 2013 and July to August of 2014 from a rural area in China. Results: During a median 6-year follow-up, we recorded 1109 deaths (610 with and 499 without hypertension). In adjusted models, as compared with BMI 22-24 kg/m2, with BMI ≤18, 18-20, 20-22, 24-26, 26-28, 28-30 and >30 kg/m2, the HRs (95% CI) for mortality in normotensive participants were 1.92 (1.23-3.00), 1.44 (1.01-2.05), 1.14 (0.82-1.58), 0.96 (0.70-1.31), 0.96 (0.65-1.43), 1.32 (0.81-2.14), and 1.32 (0.74-2.35) respectively, and in hypertensive participants were 1.85 (1.08-3.17), 1.67 (1.17-2.39), 1.29 (0.95-1.75), 1.20 (0.91-1.58), 1.10 (0.83-1.46), 1.10 (0.80-1.52), and 0.61 (0.40-0.94) respectively. The risk of mortality was lower in individuals with hypertension with overweight or obesity versus normal weight, especially in older hypertensives (≥60 years old). Sensitivity analyses gave consistent results for both normotensive and hypertensive participants. Conclusions: Low BMI was significantly associated with increased risk of all-cause mortality regardless of hypertension status in rural Chinese adults, but high BMI decreased the mortality risk among individuals with hypertension, especially in older hypertensives.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Joanna Yuet-ling Tung ◽  
Frederick Ka-wing Ho ◽  
Keith Tsz-suen Tung ◽  
Rosa Sze-man Wong ◽  
Wilfred Hing-sang Wong ◽  
...  

Abstract Background Little is known about the progression of obesity from childhood to adolescence. This study aimed to longitudinally examine the obesity status in a cohort of children across their childhood and adolescence, and to identify the factors associated with persistent obesity. Methods The study used data from School Physical Fitness Award Scheme (SPFAS), a population-based programme in Hong Kong primary and secondary schools. Students were included if they participated in the SPFAS in both 2014 (Primary 1 and 2) and 2018 (Primary 5 and 6). Their anthropometric and physical fitness parameters were analyzed. Results A total of 18,863 students were included. The baseline prevalence of obesity was 5.7 %. After 4 years, the prevalence increased to 6.7 %. Among those with obesity at baseline, 35.3 % remained obese after 4 years. The addition of baseline physical fitness level did not improve the prediction for persistent obesity. Conclusions One-third of obese students in junior primary school remained to be obese into adolescence. Their baseline physical fitness level did not improve the predictive value for future obesity. Further studies should investigate the prognostic factors that may influence the natural course of childhood obesity.


PLoS ONE ◽  
2013 ◽  
Vol 8 (10) ◽  
pp. e78594 ◽  
Author(s):  
Chun-Yip Yeung ◽  
Annette Wai-Kwan Tso ◽  
Aimin Xu ◽  
Yu Wang ◽  
Yu-Cho Woo ◽  
...  

2006 ◽  
Vol 119 (6) ◽  
pp. 1508-1510 ◽  
Author(s):  
Christian C. Abnet ◽  
Jin-Hu Fan ◽  
Farin Kamangar ◽  
Xiu-Di Sun ◽  
Philip R. Taylor ◽  
...  

2010 ◽  
Vol 19 (3) ◽  
pp. 173-181 ◽  
Author(s):  
S. K. K. Chan ◽  
I. O. L. Wong ◽  
K. Y. K. Tin ◽  
A. Fung ◽  
J. M. Johnston ◽  
...  

2021 ◽  
Author(s):  
Shing Fung Lee ◽  
Andrew Evens ◽  
Andrea Ng ◽  
Miguel-Angel Luque-Fernandez

Abstract The influence of socioeconomic status (SES) on access to standard chemotherapy and/or monoclonal antibody therapy, and associated secular trends, relative survival, and excess mortality, among diffuse large B-cell lymphoma (DLBCL) patients is not clear. We conducted a Hong Kong population-based cohort study and identified adult patients with histologically diagnosed DLBCL between 2000 and 2018. We examined the association of SES levels with the odds and the secular trends of receipt of chemotherapy and/or rituximab. Additionally, we estimated the long-term relative survival by SES utilizing Hong Kong life tables. Among 4,017 patients with DLBCL, 2,363 (58.8%) patients received both chemotherapy and rituximab and 740 (18.4%) patients received chemotherapy alone, while 1,612 (40.1%) and 914 (22.8%) patients received no rituximab or chemotherapy, respectively. On multivariable analysis, low SES was associated with lesser use of chemotherapy (odd ratio [OR], 0.44; 95% CI 0.34–0.57) and rituximab (OR, 0.41; 95% CI, 0.32–0.52). The socioeconomic disparity for either treatment showed no secular trend of change. Additionally, patients with low SES showed increased excess mortality, with a hazard ratio of 2.34 (95% CI, 1.67–3.28). Improving survival outcomes for patients with DLBCL requires provision of best available medical care and securing access to treatment regardless of patients’ SES.


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