scholarly journals Stillbirths in Multiple Births: Test of Independence

2006 ◽  
Vol 9 (5) ◽  
pp. 677-684 ◽  
Author(s):  
Johan Fellman ◽  
Aldur W. Eriksson

AbstractThe stillbirth rate in twins is a more sensitive indicator of environmental hazards than the stillbirth rate in singletons. Medical care or other socioeconomic factors may be more influential for perinatal survival in twin than in single deliveries. Studies have indicated that stillbirths among children in a set of multiple maternities are not independent. Models were considered assuming independent outcomes within a set of multiple maternities. Analyses of the stillbirth rates confirm that the risk of stillbirth among males is almost constantly higher than among females. Any model introduced should assume different stillbirth rates for males and females. The models were tested with both maximum likelihood and minimum χ2 methods. Data was analyzed from Sweden, the Åland Islands, Saxony, England and Wales, and significant discrepancies obtained from the independence models. The same-sexed twin data contain both monozygotic and dizygotic twin sets with apparently different stillbirth rates. Consequently, for same-sexed twins the proposed model could be considered too simple. After improvement by splitting the same-sexed data into monozygotic and dizygotic twin sets, the dependence still remains. The proportion of both same-sexed and opposite-sexed twin pairs that contain two stillborn is greater than what the stillbirth rates and the independence should indicate. Consequently, stillbirth rate estimates based on the relative frequency of twin sets with two stillborn children have a positive bias. When the stillbirth rate decreases, the number of sets with two stillborn children decreases more slowly than would be indicated by independence.

2009 ◽  
Vol 12 (1) ◽  
pp. 79-85 ◽  
Author(s):  
Jill Hardin ◽  
Steve Selvin ◽  
Suzan L. Carmichael ◽  
Gary M. Shaw

AbstractThis study presents a general model of two binary variables and applies it to twin sex pairing data from 21 twin data sources to estimate the frequency of dizygotic twins. The purpose of this study is to clarify the relationship between maximum likelihood and Weinberg's differential rule zygosity estimation methods. We explore the accuracy of these zygosity estimation measures in relation to twin ascertainment methods and the probability of a male. Twin sex pairing data from 21 twin data sources representing 15 countries was collected for use in this study. Maximum likelihood estimation of the probability of dizygotic twins is applied to describe the variation in the frequency of dizygotic twin births. The differences between maximum likelihood and Weinberg's differential rule zygosity estimation methods are presented as a function of twin data ascertainment method and the probability of a male. Maximum likelihood estimation of the probability of dizygotic twins ranges from 0.083 (95% approximate CI: 0.082, 0.085) to 0.750 (95% approximate CI: 0.749, 0.752) for voluntary ascertainment data sources and from 0.374 (95% approximate CI: 0.373, 0.375) to 0.987 (95% approximate CI: 0.959, 1.016) for active ascertainment data sources. In 17 of the 21 twin data sources differences of 0.01 or less occur between maximum likelihood and Weinberg zygosity estimation methods. The Weinberg and maximum likelihood estimates are negligibly different in most applications. Using the above general maximum likelihood estimate, the probability of a dizygotic twin is subject to substantial variation that is largely a function of twin data ascertainment method.


Author(s):  
Zubair Ahmad Ahmad ◽  
Eisa Mahmoudi Mahmoudi ◽  
G. G. Hamedani

Actuaries are often in search of nding an adequate loss model in the scenario of actuarial and financial risk management problems. In this work, we propose a new approach to obtain a new class of loss distributions. A special sub-model of the proposed family, called the Weibull-loss model isconsidered in detail. Some mathematical properties are derived and maximum likelihood estimates of the model parameters are obtained. Certain characterizations of the proposed family are also provided. A simulation study is done to evaluate the performance of the maximum likelihood estimators. Finally, an application of the proposed model to the vehicle insurance loss data set is presented.


2020 ◽  
Vol 9 (1) ◽  
pp. 61-81
Author(s):  
Lazhar BENKHELIFA

A new lifetime model, with four positive parameters, called the Weibull Birnbaum-Saunders distribution is proposed. The proposed model extends the Birnbaum-Saunders distribution and provides great flexibility in modeling data in practice. Some mathematical properties of the new distribution are obtained including expansions for the cumulative and density functions, moments, generating function, mean deviations, order statistics and reliability. Estimation of the model parameters is carried out by the maximum likelihood estimation method. A simulation study is presented to show the performance of the maximum likelihood estimates of the model parameters. The flexibility of the new model is examined by applying it to two real data sets.


2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Sandeep Kumar Maurya ◽  
Sanjay K Singh ◽  
Umesh Singh

A one parameter right skewed, upside down bathtub type, heavy-tailed distribution is derived. Various statistical properties and maximum likelihood approaches for estimation purpose are studied. Five different real data sets with four different models are considered to illustrate the suitability of the proposed model.


2018 ◽  
Author(s):  
Jingxian Liu ◽  
Jackson Champer ◽  
Chen Liu ◽  
Joan Chung ◽  
Riona Reeves ◽  
...  

AbstractEstimating fitness differences between allelic variants is a central goal of experimental evolution. Current methods for inferring selection from allele frequency time series typically assume that evolutionary dynamics at the locus of interest can be described by a fixed selection coefficient. However, fitness is an aggregate of several components including mating success, fecundity, and viability, and distinguishing between these components could be critical in many scenarios. Here we develop a flexible maximum likelihood framework that can disentangle different components of fitness and estimate them individually in males and females from genotype frequency data. As a proof-of-principle, we apply our method to experimentally-evolved cage populations of Drosophila melanogaster, in which we tracked the relative frequencies of a loss-of-function and wild-type allele of yellow. This X-linked gene produces a recessive yellow phenotype when disrupted and is involved in male courtship ability. We find that the fitness costs of the yellow phenotype take the form of substantially reduced mating preference of wild-type females for yellow males, together with a modest reduction in the viability of yellow males and females. Our framework should be generally applicable to situations where it is important to quantify fitness components of specific genetic variants, including quantitative characterization of the population dynamics of CRISPR gene drives.


1993 ◽  
Vol 57 (2) ◽  
pp. 326-328 ◽  
Author(s):  
G. A. María ◽  
K. G. Boldman ◽  
L. D. van Vleck

A total of 1855 records were analysed using restricted maximum likelihood (REML) techniques to estimate heritabilities separately for males and females lambs on birth weight (BW), weaning weight (WW), 90-day weight (W90) and average daily gains birth to weaning (Cl) and weaning to 90 days (C2). An animal model including fixed effects of year × season, parity, litter size and rearing type; and random effects of direct genetic effect (h2D) and residual was applied. Estimates ofh2Dfor BWwere 048 (males) and 0·50 (females); for WW 0·35 (males) and 0·22 (females); for W90 0·21 (males) and 0·31 (females); for Cl 0·20 (males) and 0·25 (females); and for C2 0·18 (males) and 0·29 (females).


2006 ◽  
Vol 9 (4) ◽  
pp. 591-596 ◽  
Author(s):  
Aldur W. Eriksson ◽  
Johan Fellman

AbstractTemporal variations in the stillbirth rate among singletons, twins and triplets in Sweden between 1869 and 1967 were studied. Both among single and multiple births there were marked secular decreasing trends in the stillbirth rates. Based on our long time series since 1869, this study confirms that among twins and triplets the stillbirth rate was higher among same-sexed than among opposite-sexed sets. Comparisons between the stillbirth rates among twin births in urban and rural regions indicate higher stillbirth rates in rural areas. In addition, the stillbirth rates among twins of unmarried mothers were higher than those of twins of married mothers. These findings also hold for both same-sexed and opposite-sexed twin pairs. Analyses of the stillbirth rates for singletons and for different types of twins indicate that up to 1950 the risk of stillbirth among males was almost constantly between 15% to 20% higher than among females. After that the difference in the risk decreased. Comparisons with other populations were performed.


Author(s):  
Hanan Alamoudi ◽  
Salwa‎ Mousa‎ ◽  
Lamya Baharith

This article introduces a new location-scale regression model based on a log-Fréchet distribution. Maximum likelihood and Jackknife methods are used to estimate the new model parameters for censored data. Martingale and deviance residuals are obtained to check model assumptions, data validity, and detect outliers. Moreover, global influence is used to detect influential observations. Monte Carlo simulation study is provided to compare the performance of the maximum likelihood and jackknife estimators for different sample sizes and censoring percentages. The empirical distribution of the martingale and deviance residuals of the proposed model is examined. A real lifetime heart transplant data is analyzed under the log-Fréchet regression model to illustrate the satisfactory results of the proposed model.


Mathematics ◽  
2020 ◽  
Vol 8 (3) ◽  
pp. 358 ◽  
Author(s):  
M. S. Eliwa ◽  
Ziyad Ali Alhussain ◽  
M. El-Morshedy

Alizadeh et al. introduced a flexible family of distributions, in the so-called Gompertz-G family. In this article, a discrete analogue of the Gompertz-G family is proposed. We also study some of its distributional properties and reliability characteristics. After introducing the general class, three special models of the new family are discussed in detail. The maximum likelihood method is used for estimating the family parameters. A simulation study is carried out to assess the performance of the family parameters. Finally, the flexibility of the new family is illustrated by means of four genuine datasets, and it is found that the proposed model provides a better fit than the competitive distributions.


2016 ◽  
Vol 2016 ◽  
pp. 1-12 ◽  
Author(s):  
Marcelo Bourguignon ◽  
Indranil Ghosh ◽  
Gauss M. Cordeiro

The transmuted family of distributions has been receiving increased attention over the last few years. For a baselineGdistribution, we derive a simple representation for the transmuted-Gfamily density function as a linear mixture of theGand exponentiated-Gdensities. We investigate the asymptotes and shapes and obtain explicit expressions for the ordinary and incomplete moments, quantile and generating functions, mean deviations, Rényi and Shannon entropies, and order statistics and their moments. We estimate the model parameters of the family by the method of maximum likelihood. We prove empirically the flexibility of the proposed model by means of an application to a real data set.


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