scholarly journals Single Layer Graphene Assisted Transmission Mode Continuous Wave Laser Desorption for Micrometer Spatial Resolution Atmospheric Pressure Mass Spectrometry Imaging

2019 ◽  
Vol 26 (2) ◽  
pp. 120-121
Author(s):  
Jae Young Kim ◽  
Dae Won Moon
2020 ◽  
Vol 12 (10) ◽  
pp. 1517-1523
Author(s):  
Jae Young Kim ◽  
Heejin Lim ◽  
Sun Young Lee ◽  
Gwanjin Lee ◽  
Dong-Kwon Lim ◽  
...  

We demonstrate continuous-wave laser-based ambient mass spectrometry imaging with the use of a gold-nanoparticle layer substrate. When a fresh tissue slice is placed on a gold-nanoparticle layer substrate and irradiated with a 532-nm continuous-wave laser, the transmission-mode laser configuration provides precise desorption performance to facilitate mass spectrometry imaging. The subsequent ionization process with nonthermal atmospheric pressure plasma jets generates sufficient amounts of molecular ions. By using this method, micrometer-spatial-resolution mass spectrometry imaging of humid tissues can be obtained. The gold-nanoparticle layer substrates can be prepared and stored in advance of the experiment, resulting in simplified specimen preparation and an advantage in faster preparing of fresh tissue specimen for analysis.


2021 ◽  
Vol 18 (3) ◽  
pp. 316-320 ◽  
Author(s):  
Heejin Lim ◽  
Sun Young Lee ◽  
Yereum Park ◽  
Hyeonggyu Jin ◽  
Daeha Seo ◽  
...  

RSC Advances ◽  
2018 ◽  
Vol 8 (15) ◽  
pp. 8021-8025 ◽  
Author(s):  
Jae Young Kim ◽  
Eun Seok Seo ◽  
Hee Jin Lim ◽  
Hyunmin Kim ◽  
Ji-Won Park ◽  
...  

Micrometer-resolution mass spectrometric imaging of live hippocampal tissue is achieved with a highly efficient desorption of biomolecules using a 532 nm continuous wave laser and gold nanoparticles or graphene oxide as an energy transporter.


2010 ◽  
Vol 645-648 ◽  
pp. 565-568 ◽  
Author(s):  
Rositza Yakimova ◽  
Chariya Virojanadara ◽  
Daniela Gogova ◽  
Mikael Syväjärvi ◽  
D. Siche ◽  
...  

We are aiming at understanding the graphene formation mechanism on different SiC polytypes (6H, 4H and 3C) and orientations with the ultimate goal to fabricate large area graphene (up to 2 inch) with controlled number of monolayers and spatial uniformity. To reach the objectives we are using high-temperature atmospheric pressure sublimation process in an inductively heated furnace. The epitaxial graphene is characterized by ARPES, LEEM and Raman spectroscopy. Theoretical studies are employed to get better insight of graphene patterns and stability. Reproducible results of single layer graphene on the Si-face of 6H and 4H-SiC polytypes have been attained. It is demonstrated that thickness uniformity of graphene is very sensitive to the substrate miscut.


2020 ◽  
Vol 5 (3-4) ◽  
pp. 75-81
Author(s):  
Mopeli Samuel Fabiane ◽  
Moshawe Jack Madito ◽  
Ncholu Manyala

Abstract In this work, the role of gas kinetics in the growth of lobed graphene domains by atmospheric pressure chemical vapor deposition (AP-CVD) is elucidated by sandwiching Cu foil between Si/SiO2 wafers. Two different growths were carried out: (1) A Cu foil was placed at the center of a quartz tube in AP-CVD for graphene growth and (2) another Cu foil was sandwiched between Si/SiO2 wafers to alter the nucleation growth kinetics of graphene domains to mimic those in low-pressure chemical vapor deposition (LP-CVD). From the scanning electron microscopy (SEM) images, the graphene domains of the sandwiched Cu foil displayed mostly four-lobed, parallel-sided domains which are usually obtained under LP-CVD as compared to Cu foil without sandwiching which showed typical hexagonal graphene domains of AP-CVD. The Raman spectroscopy confirmed that the domains are single-layer graphene. An electron backscatter diffraction (EBSD) showed that the Cu foil is predominantly (001). The results of this study agree with the theoretical predictions of growth kinetics in graphene synthesis by CVD and showed that it is possible to obtain single-layer graphene domains which are usually obtained under LP-CVD by restricting the gas flux through the boundary layer. Graphic abstract


Carbon ◽  
2012 ◽  
Vol 50 (1) ◽  
pp. 57-65 ◽  
Author(s):  
Baoshan Hu ◽  
Hiroki Ago ◽  
Yoshito Ito ◽  
Kenji Kawahara ◽  
Masaharu Tsuji ◽  
...  

2007 ◽  
Vol 177 (4S) ◽  
pp. 614-614
Author(s):  
Thorsten Bach ◽  
Thomas R.W. Herrmann ◽  
Roman Ganzer ◽  
Andreas J. Gross

2019 ◽  
Vol 33 (31) ◽  
pp. 1950384
Author(s):  
Di Lu ◽  
Yu-E Yang ◽  
Weichun Zhang ◽  
Caixia Wang ◽  
Jining Fang ◽  
...  

We have investigated Raman spectra of the G and 2D lines of a single-layer graphene (SLG) with metallic contacts. The shift of the G and 2D lines is correlated to two different factors. Before performing annealing treatment or annealing under low temperature, the electron transfer on graphene surface is dominated by nonuniform strain effect. As the annealing treatment is enhanced, however, a suitable annealing treatment can eliminate the nonuniform strain effect where the relative work function (WF) between graphene and metal becomes a main factor to determine electronic transfer. Moreover, it is confirmed that the optimized annealing treatment can also decrease effectively the structural defect and induced disorder in graphene due to metallic contacts.


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