scholarly journals Physico-Chemical and Analytical Study of Metoprolol Tartrate: An Antihypertensive Drug

2017 ◽  
Vol 29 (6) ◽  
pp. 1351-1356 ◽  
Author(s):  
Anwar A. Wassel ◽  
N.O. Alzamel ◽  
M.A. Alkhaldi ◽  
N. Ouerfelli ◽  
A.A. Al-Arfaj
Author(s):  
Jigyasa Pathak ◽  
Aswathi M. P. ◽  
B. R. Patel ◽  
Harisha C. R. ◽  
Shukla Vinay J.

Background: Desmodium velutinum (Fabaceae) is one of the wild edible plants used traditionally to treat diarrhoea, haematuria, infertility and also externally used to treat scorpion bites. Though various parts of the plant have been used for therapeutic purpose, panchanga of the plant has not been studied for its Pharmacognostical and phytochemical characteristics in detail, following scientific parameters. Hence in the present study Desmodium velutinum whole plant has been studied for its pharmacognostical and phytochemical characters and compared with commonly used species Desmodium gangeticum. Methods: Whole plant of Desmodim velutinum was collected from Paikmal, Odisha and Desmodium gangeticum was collected from Junagarh, Gujarat in the month of November 2019 following good collection practices and shade dried. Pharmacognostical study and analytical study were performed following standard pharmacopoeial procedures. Results: Whole plant (Panchanga) of former is sweetish and latter is bitter. Powder microscopy of Desmodium gangeticum showed presence of rhomboidal crystals and lignified annular and spiral vessels. Desmodium velutinum showed presence of prismatic crystals and lignified pitted vessels. Physico-chemical analysis showed higher loss on drying in Desmodium gangeticum, and higher water soluble extractive values of Desmodium velutinum. Phytochemical estimation showed the presence of Proteins, tannins, and carbohydrates in both samples. HPTLC study showed similar Rf value 0.82 and 0.94 at 254 and 0.03 and 0.41 at 366nm. Conclusion: Basing upon the analytical and microscopic similarities Desmodium velutinum may be considered as substitute of Desmodium gangeticum


2016 ◽  
Vol 12 (33) ◽  
pp. 554
Author(s):  
Ajeagah Gideon Aghaindum ◽  
Asi Quiggle Atud ◽  
Nola Moïse

With an aim of characterizing the cysts of flagellated enteric protozoa present in groundwater of the town of Yaoundé, a descriptive and analytical study was carried out from February to July 2015 on the samples of 6 springs and 6 wells in 6 quarters of the city. The physico-chemical analysis proceeded at the same time on the field and at the laboratory. The observation of the cysts of the flagellated protozoa was done under the inverted microscope of mark Olympus CK2 to the objective 40X after concentration of the samples according to the method of sedimentation and the method of floating. The physicochemical analysis revealed slightly acid water (6, 04 ± 0, 49 U.C), average mineral-bearing (533, 70 ± 346, 18 µS/cm) and rich in suspended matter (14, 14 ± 11, 35 mg/L). The biological analyses revealed the presence of the cysts of the flagellated Protozoa with average densities of 162±115 cysts/L for Giardia intestinalis, 262 ± 280 cysts /L for Chilomastix mesnili, 89±101 cysts /L for Enteromonas hominis and 72 ± 80 cysts /L for Retortamonas intestinalis. In general, the greatest densities of cysts were recorded during the rainy season. The statistical tests revealed positive correlation between the cystic densities with MES, the color, turbidity and the organic matter (p < 0,05), and also negative correlation with nitrate (p < 0,05).This very high parasitological pollution makes water unfit for consumption. The use of untreated spring waters and wells could constitute a significant heath for the households living in the zone of study.


Author(s):  
Kranti Natthuji Khekale

Ayaskriti is an ayurvedic formulation containing iron. It is a specific metal processing technique developed in ancient times to make iron suitable for internal use. Objective: To prepare and physicochemically evaluate lauha Ayaskriti (shusruta) and lauha bhasma. Materials and methods: lauha Ayaskriti (shusruta) and lauha bhasma was prepared as per ayurvedic text and characterized by Organoleptic characters, physico-chemical parameters. Results: This study clearly revealed bhasma prepared as per Sushruta and Rastangini are passed as per ayurvedic bhasma pariksha. Conclusion: The study of XRF of lauha Ayaskriti and lauha bhasma value of fe is persent in the elemental form along with other form of oxide. Further studies are required to prove the medicinal efficacy of this medicine.  


2020 ◽  
Vol 5 (05) ◽  
pp. 214-219
Author(s):  
Arya Elias ◽  
Pramod C. Baragi ◽  
Kashinath Hadimur ◽  
K. A. Patil ◽  
Khazi Rahimbi

Background: Shilajatu or Adrija is one of the Maharasa, which is considered as a wonderful medicine in Ayurveda. It is named as it comes out of the stones heated by the sun in summer in the form of thick blackish exudation having many shades. Since it contain stone, mud, wood, sand and various physical and metallic impurities, Shodhana (Purification) of Shilajatu is a mandatory procedure. It has been used as a prime ingredient in many formulations mainly for Prameha, Sotha, Pandu Roga, Kshaya, Swasa, Pliha Vrudhi, Jwara, Agnimandya, Apasmara, etc. Objectives: Shodhana of Ashudha Shilajatu and Physico chemical analysis of Shodhita Shilajatu. Materials and Methods: Bhringaraja Swarasa for Shodhana of Shilajatu. Results:It took 8 days for completion of Shilajatu Shodhana. XRD Analysis report indicates that the sample Shilajatu was Amorphous material. Conclusion: Total yield of Shodhita Shilajatu was 99.6%. The Sample of Shilajatu was found to be Amorphous material in XRD Analysis hence crystal structure was not identified.


2020 ◽  
Vol 5 (05) ◽  
pp. 241-244
Author(s):  
Baban Rathod ◽  
Gangaprasad Asore ◽  
Sujata Haribhau Sankpal

Durvadya Taila is medicated oil used in Ayurveda for Kacchu, Vicharchika and Pama (types of Skin diseases) which is caused by vitiated Kapha or Pitta Dosha. Durva is one of the classical drugs of herbal origin, for the management of different disease conditions. The aim of the present study is to do physico-chemical standards for above Durvadya Taila and its conversion into Durvadya Taila Cream. These two formulations have a special importance from pharmaceutical point of view when compared to usual Taila or cream. In present article, we are trying to study analytical results of Durvadya Taila w.s.r. to Durvadya Taila cream. The skin constitutes a major part of the body and serves as a dividing line between the individual and his environment. In the Ayurvedic classics, Bahir Parimarjana means, the medicine intended for external use only. For that purpose, in Ayurveda different forms of external applications are described for the convenience of treatment of different diseases. They are Lepa, Udvartana, Upanaha, Abhyanga, Malahara etc. Without defining creams under Panchavidha Kashaya Kalpana, we can correlate Cream preparation with Lepa or Malahara Kalpana. Creams are those emulsions, which are either oil in-water or water-in-oil type. Durvadya Taila is medicated oil used in Ayurveda for Kacchu, Vicharchika and Pama which comes under Kushtha Rogadhikar.


Author(s):  
Abhishek Abhishek ◽  
Ashok Kumar BN ◽  
Sujatha K. ◽  
Sunil Kumar

Introduction: Mrityunjaya Rasa is a herbo–mineral formulation mentioned under Jwara Chikitsa in Rasendra Sara Sangraha along with different Anupanas. It is having ingredients like Shudha Hingula, Shudha Gandhaka, Shudha Vatsanabha, Shudha Tankana, Pippali and Maricha which show significant result on various types of fever. Aim: To prepare Mrityunjaya Rasa as per guidelines given in classical text book Rasendra Sara Sangraha and to validate physico-chemical analysis of the sample. Methods: The preparation of Mrityunjaya Rasa was carried out at practical hall, Department of Rasashastra and Bhaishajya Kalpana, Shri Dharmasthala Manjunatheshwara College of Ayurveda, Kuthpady, Udupi, Karnataka. It was subjected to analysis on parameters like organoleptic characters, loss on drying, total ash, acid insoluble ash, water soluble ash, pH, alcohol soluble extractive value, and water soluble extractive value. Results: The results of Analytical study showed specific characteristics which are in accordance with the properties of Mrityunjaya Rasa. Conclusion: The study showed significant results, which proves quality of the drugs and efficacy.


2018 ◽  
Vol 7 (2) ◽  
pp. 181 ◽  
Author(s):  
Latifa Shaheen Al-Naimi ◽  
Tochukwu Innocent Mgbeojedo

Hydrogeochemical analyses of groundwater samples in Shamal area were undertaken to assess the groundwater chemistry of the area and hence determine its suitability for irrigation and other purposes. Thirteen groundwater samples were freshly collected from different functional wells in the area and were analyzed for different physico-chemical parameters.  The analyzed parameters include TDS, EC, major cations and anions. The water quality study shows that EC ranges from 7891.88-20 736.84 μS/cm, TDS values range from 5050.80-13 271.58 mg/l. Analytical study of water samples shows that sodium varies from 1316.38-3432.39 mg/l, calcium varies from 300.81-799.93 mg/l, magnesium varies from 126.66-381.81 mg/l, potassium varies from 74-181.02 mg/l, chloride values range from 2177.75-6058 mg/l, sulphate values range from 743.87-2448.79 mg/l and bicarbonate values range from 23.13-240.3 mg/l. The high concentrations of sodium and chloride ions are indicators of saline water intrusion. The analyses of the hydrogeochemical ratios were also done to highlight the groundwater genesis and origin of mineralization. The water samples were analyzed for suitability for irrigation using various classification criteria and mathematical formula. The results from analysis of KR, SAR, SSP, PS, EC and %Na all indicate that the water in the area is unfit for use in irrigation.


Author(s):  
Dr.Ramakiran ◽  
Dr.Harshitha M

Drug research is an important part of pharmaceutical field especially in Ayurveda pharmaceutics to revalidate and establish various formulations. Ghritha kalpana has got prime importance due to a special property of Ghritha i.e Samskarasyanuvartana. Ksheera ghritha and Ghritha are explained with different properties in Ayurveda classics. Present study is to compare between Yastimadhu Ksheera ghritha and classical Yastimadhu ghritha by organoleptic and analytical parameters. Ksheera ghritha procedure may bypass the long procedure , maximise the percentage of extract in Ghritha. Reference of Ksheera ghritha is available in various classical texts like Sushruta samhitha1 etc. Ksheera ghritha said to have properties like Netrya , Sangrahi , Rakthapitta hara etc. Ksheera ghritha of Yastimadhu prepared by preparing Ksheerapaka taken as G1 and Yastimadhu Ghritha prepared by normal classical way taken as G2. Analytical study for standardization of both samples were carried out on the basis of classically illustrated organoleptic tests and modern parameters of physico-chemical properties like LOD, Refractive index , Saponification value etc., and TLC done for qualitative analysis. By this study the major difference between Ksheera ghritha and Ghritha are established giving further scope for clinical research to establish efficacy of same. KEY WORDS : Ayurveda, Ghritha, Yastimadhu, Ksheerapaka.


2020 ◽  
Vol 5 (04) ◽  
pp. 82-85
Author(s):  
Munna Kumar ◽  
Ajay Kumar Singh ◽  
Uma Shankar Chaturvedi ◽  
Mukesh Kumar

Ayurveda the science of life gives importance to the balance between nature and human relationship; and Rasashastra, one of its associate wings can be considered to hold a key role since it deals in almost all the substances created by nature and marshals then for alleviating the diseases. The therapeutic efficacy of drugs depends upon the genuineness of raw material and right. Shilajeet is an important herbomineral drug among the Maharasa. Describing its importance Charaka has said, “there is hardly any curable disease which cannot be alleviated or cured with the aid of Shilajeet. Aim of study is to evaluate the Physico-chemical parameterof Salsaradi Gana Bhawit Shilajatu. Shilajatu and all raw drugs were obtained from P.G. Department, G.A.C.H. Patna and Shilajeet Shodhana was done by Triphala Kwatha and three times Bhawana by Salsaradigana (Dravyas) Kwatha. All samples were analyzed at Laboratory of Govt. Ayurveda College and Hospital Patna. It found that Shilajatu after Bhawana appeared as semi solid colour brownish black, soft in consistency and having typical smell.


Author(s):  
Sorab Gaind ◽  
Pradeep Agnihotri

Analytical study of any drug is essential to standardize it. Analytical study is carried out to check drug quality. For this purpose some analytical tests are performed and their results are compared with standard parameters. The drug fulfilling these criteria can be taken as standard drug and can be used for therapeutic purpose. Percentage of total mercury in Shadguna Kajjali and Shadguna balijarita rasasindur was 40.03%, and 84.17%. Total Sulphur in Shadguna Kajjali and Shadguna balijarita rasasindur was 43.07% and 11.16%. Percentage of free sulfur in Shadguna Kajjali and Shadguna balijarita rasasindur was 22.11%. XRD of Shadguna balijarita Rasasindur were identified as Cinnabar (Hgs) with Hexagonal Crystal Structure having primitive lattice. In this paper Physico-Chemical Analysis of Shadguna Kajjali and Shadguna balijarita rasasindura is done.


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