scholarly journals Correlation between serum zinc level and simple febrile seizure in children

2016 ◽  
Vol 50 (6) ◽  
pp. 326 ◽  
Author(s):  
Lusiana Margaretha ◽  
Nurhayati Masloman
Keyword(s):  
Central Nervous System ◽  
Acute Diarrhea ◽  
Febrile Seizure ◽  
Serum Zinc ◽  
Hemorrhagic Fever ◽  
Zinc Level ◽  
Acute Respiratory Tract Infection ◽  
Sectional Study ◽  
Serum Zinc Level ◽  
History Of

Background Simple febrile seizure is the most common form of seizure which occurs during childhood period. Zinc, one of microelements in human body, has an important role in central nervous system formation.Objectives To find out serum zinc level in simple febrile seizure patients and the correlation between serum zinc level and simplefebrile seizure.Methods This cros-sectional study was conducted at R. D. Kandoll Hospital, Tingkat III Teling Hospital and Pancaran Kasih Hospital, Manado on April 5th - June 15th, 2009.Results Diagnosis for febrile v.ithout seizure patients were 12 with acute respiratory tract infection (ARl), 6 dengue hemorrhagic fever (DHF), 6 acute diarrhea v.ithout dehydration and 1 ARI with DHF, while simple febrile seizure were 19 ARI, five acute diarrhea v.ithout dehydration and one ARI v.ith DHF. There were no significant differences of age, gender and nutritional status in two groups. F amily history of febrile seizure, febrile period and body temperature in two groups were significantly different. Mean serum zinc level in simple febrile seizure and febrile v.ithout seizure were 8.83 μmol/L and 13.72 μmol/L, respectively. Mean serum zinc level in simple febrile seizure children with seizure period <5 minutes, 5-<10 minutes and 10-15 minutes were 10.27 (SD 0.25)  μmol/L, 9.02 (SD 0.81) ) μmol/L and 6.90 (SD) 0.98 μmol/L, respectively.Conclusions There is correlation between serum zinc level and simple febrile seizure. The lesser serum zinc level, the longer duration of seizure occurs in simple febrile seizure.

scholarly journals Comparative study of serum zinc concentration in recurrent herpes labialis patients and healthy individuals

2020 ◽  
Author(s):  
Zahra Ranjbar ◽  
Maryam Zahed ◽  
Mohammad Ali Ranjbar ◽  
Zahra Shirmardan
Keyword(s):  
Healthy Subjects ◽  
Serum Zinc ◽  
Zinc Level ◽  
Therapeutic Effects ◽  
Herpes Labialis ◽  
Healthy Individuals ◽  
Serum Zinc Level ◽  
Significant Difference ◽  
Recurrent Herpes ◽  
History Of

Abstract Background: Recurrent herpes labialis (RHL) is one of the most common recurrent infective vesiculoulcerative lesions. Topical and systemic administration of Zinc compounds has been found to have preventive and therapeutic effects. The purpose of this article is to evaluate the serum level of zinc in patients with RHL and healthy individuals. Methods: This cross-sectional study was performed on 43 patients with the history of recurrent herpers labialis and 42 healthy subjects with no history of the lesion. Blood samples were taken and serum zinc level was measured. Chi-Square test was used to compare the qualitative relationships and to compare the quantitative relationships independent T-test was used. To observe the relationship of quantitative factors including serum zinc level, the number of relapses and recovery rates correlation test was taken. Results: The results show that serum zinc level has no significant difference in healthy subjects and patients (p> 0.05). Also, zinc level was not related to age and sex factors and frequency of relapse (P> 0.05). But surprisingly in the patients group, there was a significant relationship between zinc level and recovery period. As the serum zinc level was lower, the duration of recovery was significantly higher (p =0.009). Conclusion: The results of this study indicate that zinc deficiency is a risk factor for increasing the duration of herpes labialis lesions. Therefore, the evaluation of serum zinc level in subjects with recurrent herpes labialis and subsequent administration of zinc is recommended in such patients.

scholarly journals Association of Serum Zinc Level with Febrile Seizures in Children

2021 ◽  
pp. 200-203
Author(s):  
Maryum Naveed ◽  
Rimsha Mohsin ◽  
Palwasha Khan
Keyword(s):  
Febrile Seizure ◽  
Serum Zinc ◽  
Febrile Convulsion ◽  
Febrile Seizures ◽  
Cross Sectional Study ◽  
Zinc Level ◽  
Control Group ◽  
Case Group ◽  
Serum Zinc Level ◽  
Cross Sectional

Introduction: Febrile seizure (FS), previously known as febrile convulsion, is the most common seizure in children. FS usually occurs between six months and five years of age. Aims and objectives: The main objective of the study is to find the association of serum zinc level with febrile seizures in children of Pakistan. Material and methods: This cross sectional study was conducted at Mayo Hospital, Lahore during June 2020 to January 2021. The data was collected from 164 patients of both genders. Results: The data was collected from 164 patients. In the case group, 46 children were male (53.3%), and 36 children (46.7%) were female. In the control group 44 children were male (43.3%) and 38 children were female (56.7%). The age of all participants was between one months and six years. Conclusion: It is concluded that low serum zinc levels are fairly un-sufficient to support the hypothesis that Zinc deficiency could not be a potential risk factor for febrile seizure in children.

scholarly journals Estimation of serum zinc levels in children with febrile convulsions

2018 ◽  
Vol 5 (4) ◽  
pp. 1518 ◽  
Author(s):  
Ubaidur Rehman H. ◽  
Shamshad Ahmed Khan ◽  
Prakash R. Saldanha
Keyword(s):  
Serum Zinc ◽  
Febrile Seizures ◽  
Cross Sectional Study ◽  
Zinc Level ◽  
Sectional Study ◽  
Serum Zinc Level ◽  
Cross Sectional ◽  
Significant Difference ◽  
Zinc Levels ◽  
Serum Zinc Levels

Background: Febrile seizures are the most common form of convulsion in children with the aged between 6 months to 6 years. Different studies have shown that reduction of zinc leads to the incidence of febrile seizures in children. This study was conducted with the goal of examination of the zinc level in the patients with Febrile Seizures.Methods: This cross sectional study was conducted on 50 children in two equal groups of children with febrile seizures, febrile children without seizures. In order to examine the zinc level blood samples were taken of all subjects and the zinc level of these patients was determined. The data was analyzed using the SPSS-16 statistical software and by descriptive statistical tests.Results: 31 males (47.2%) and 19 female children (52.8%) with the average age of 27.23±15.3 months were examined. The two groups had no significant difference in terms of age and sex. The average of zinc level in the patients with Febrile Seizures was 57.4 µg/dL and it was 116 µg/dL in the febrile children without FS there was a significant difference between the two groups in terms of the zinc level (P=0.01).Conclusions: The low serum zinc level in the group of patients with Febrile Seizures compared with children without febrile seizures indicate the existence of a relationship between the serum zinc level and development of FS in children aged between 6 months and 6 years.

scholarly journals ROLE OF SERUM ZINC LEVEL IN CHILDREN WITH FEBRILE CONVULSIONS

2019 ◽  
Vol 3 (9) ◽  
Author(s):  
Dr. Laxminarayan Nagal ◽  
Dr Jagdish Dabi ◽  
Dr. Harish Kumar Mourya
Keyword(s):  
Febrile Seizure ◽  
Tertiary Care ◽  
Serum Zinc ◽  
Zinc Level ◽  
Control Group ◽  
Serum Zinc Level ◽  
Tertiary Care Centre ◽  
Febrile Convulsions ◽  
Zinc Levels ◽  
And Control

Background: The aim of the present study was to determine whether there were any changes in serum zinc level in children with febrile seizure in comparison with febrile children without seizure. Methods: A prospective observational study was done on 100 children, admitted in a tertiary care centre. Of these 50 children were diagnosed to have febrile convulsions. The other 50 were febrile children without seizures. Serum zinc levels were measured in all 100 subjects using calorimetric methods. Data was analyzed using SPSS version 22. Results: In present study, we studied 50 children (36 males, 14 females) with febrile seizure and a control group of 50 patients (37 male, 13 female). The mean ages of patients in the febrile seizure and control group were 25.01±14.07 months and 26.07±13.6 months, respectively. Mean zinc level was 69.78±13.13mcg/dl and 80.72±10.21 mcg/dl in study and control groups respectively and this difference was found statistically highly significant (p<0.001). Conclusion: Our findings revealed that serum zinc level was significantly lower in children with febrile seizure in comparison with children without seizure. Keywords: febrile seizure, children, epilepsy.

scholarly journals Is Serum Zinc Level Associated with Prediabetes and Diabetes?: A Cross-Sectional Study from Bangladesh

PLoS ONE ◽  
2013 ◽  
Vol 8 (4) ◽  
pp. e61776 ◽  
Author(s):  
Md. Rafiqul Islam ◽  
Iqbal Arslan ◽  
John Attia ◽  
Mark McEvoy ◽  
Patrick McElduff ◽  
...  
Keyword(s):  
Serum Zinc ◽  
Cross Sectional Study ◽  
Zinc Level ◽  
Sectional Study ◽  
Serum Zinc Level ◽  
Cross Sectional

scholarly journals Serum zinc levels and clinical severity of dengue infection in children

2009 ◽  
Vol 49 (6) ◽  
pp. 309 ◽  
Author(s):  
Nuke Yuliana ◽  
RM Ryadi Fadil ◽  
Alex Chairulfatah
Keyword(s):  
Dengue Infection ◽  
Serum Zinc ◽  
Hemorrhagic Fever ◽  
Zinc Level ◽  
Clinical Severity ◽  
Severe Dengue ◽  
Serum Zinc Level ◽  
Zinc Levels ◽  
Serum Zinc Levels ◽  
Low Serum

Background Immunopathogenesis of dengue infection revealsthe aberrant immune response. Zinc deficiency alters immuneresponse and therefore may associated with clinical severity ofdengue infection.Objective To indentifY the relationship between serum zinc levels and clinical severity of dengue infection in children.Methods A comparative study was conducted at the Departmentof Child Health Hasan Sadikin Hospital Bandung, from Februaryto March 2007. We included children aged ~ 14 years fulfilled theclinical criteria for dengue fever (OF), dengue hemorrhagic fever(DHF), and dengue shock syndrome (DSS) according to WHO(1997), confirmed with serologic test. Subjects were selectedconsecutively until met the sample size for each group. Serumzinc level were measured with atomic absorption spectroscopy(MS) on admission. Data were analyzed using Kruskal-Wallis andPearson chi square test. Significance was considered if P<0.05.Results The serum zinc levels were low in 47 (78.3%) children.The serum zinc level in OF, DHF, and DSS subjects were 56-81 (X±SO= 68.2±8.3) J.Lg/dL; 50-77 (X± SO = 61.6 ± 8. 7) J.Lg/dL;and35-52 (X± SO= 42.7 ± 5.4) j.tg/dL, respectively (P<0.001).The prevalence ratio ofDF to DHF and DHF to DSS were 1.444(P=0.311) and 3.353 (P=0.077), respectively.Conclusion Low serum zinc level were significantly different ineach clinical severity of dengue infection. However, low serum zinc level was not a risk factor for the development of severe dengue infection in children.

scholarly journals Acute Diarrhea in Exclusively Breast Fed Infants in relation to Zinc Level

2021 ◽  
Vol 15 (5) ◽  
pp. 1431-1435
Keyword(s):  
Zinc Deficiency ◽  
Acute Diarrhea ◽  
Serum Zinc ◽  
Zinc Level ◽  
Healthy Control Group ◽  
Control Group ◽  
Serum Zinc Level ◽  
Healthy Control ◽  
The Mean ◽  
Breast Fed

Background: Zinc deficiency is associated with alteration in gastrointestinal tract structure, function, and impaired immune function. Aim: To analyze the effects of zinc deficiency on the occurrence of acute diarrhea in exclusively breast-fed infants. Methods: In a case-control study, including a total of 72 exclusively breast-fed infants aged ≤ 6 months, 34 of them with acute diarrhea were in the study group and 38 infants as the healthy control group. Demographic characteristics of all infants and their parents were studied. Serum Zinc level was measured for all participants. Results: Zinc level had significant (p-value =0.000) differences between infants with acute diarrhea and the healthy control group. The mean serum zinc value ± SEM in children with acute diarrhea was 63.11 ± 1.7 which was significantly (p = 0.000) different from the mean serum zinc value ± SEM (78.6 ± 1.6) in healthy infants. A cut-off value 60.6μg/dl of total serum zinc level was significantly (p = 0.000) associated with a sensitivity of 100 % with the occurrence of acute diarrhea among exclusively breast-fed infants. Conclusions: Low serum zinc level is associated with the occurrence of acute diarrhea in exclusively breast-fed infants. A cutoff serum zinc value of 60.6 μg/dl has 100% sensitivity with the occurrence of acute diarrhea among breast-fed infants. Keywords: Zinc deficiency, diarrhea, infants, breastfeeding.

Serum Zinc Levels in Cirrhotic Patients Attending General and Specialty Hospitals, Yangon

2019 ◽  
Vol 31 (3) ◽  
pp. 251-256
Keyword(s):  
Clinical Practice ◽  
Hepatic Encephalopathy ◽  
Zinc Deficiency ◽  
Serum Zinc ◽  
Zinc Level ◽  
The Body ◽  
Serum Zinc Level ◽  
Cross Sectional ◽  
Cirrhotic Patients ◽  
Cirrhosis Of Liver

Cirrhosis of liver is one of the common medical problem in daily clinical practice and one of the leading causes of morbidity and mortality. Zinc is an essential trace elements for human and plays in many biological roles in the body. Among them, zinc deficiency is thought to be involved in metabolism of ammonia and causes hyperammonia that worsen hepatic encephalopathy. This study aimed to find out the severity of cirrhosis of liver was by Child Turcotte Pugh score and to investigate the associations between serum zinc level and severity of cirrhosis. A hospital-based cross-sectional descriptive study was performed on 78 patients with different underlying causes of cirrhosis of liver at the Medical Units of Yangon General Hospital and Yangon Specialty Hospital. Among the study population, Child grade A was found to be 28.21%, Child grade B was 30.77% and Child grade C was 41.03%. Regarding result of serum zinc level, 62.8% were low level, 28.2% were within normal level and 8.9% were high level. Mean value of serum zinc level in grade A was 0.68 mg/l, grade B was 0.54 mg/l and grade C was 0.48 mg/l (p=0.00). It was found out that there was a high prevalence of zinc deficiency in severe cirrhotic patients. The zinc level was significantly lowest among patients with Child-Pugh C as compare to those with Child-Pugh B and C. Severity of zinc deficiency should be requested for supplementation therapy in cirrhotic patients as to prevent complications such as hepatic encephalopathy, hepatocellular carcinoma and liver failure. Screening for zinc deficiency may need in these patients with more advanced cirrhosis because it seems to be a marker of advanced liver disease and it can be deducted that awareness of serum zinc level among cirrhotic patients is very important in clinical practice.

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