scholarly journals Zinc therapy for different causes of diarrhea

2013 ◽  
Vol 53 (6) ◽  
pp. 334
Author(s):  
Hafaz Zakky Abdillah ◽  
Supriatmo Supriatmo ◽  
Melda Deliana ◽  
Selvi Nafianti ◽  
Atan Baas Sinuhaji

Background The incidence of diarrhea in Indonesia has declinedin the past five years. In spite of the increasing number of studieson the treatment for acute diarrhea, especially the use of zinc,it is not known if bacterial vs. non-bacterial etiology makes adifference in the reduction of severity of acute diarrhea in childrenon zinc therapy.Objective To assess the effect of zinc therapy in reducing theseverity of acute bacterial and non-bacterial diarrhea.Methods We performed a cross-sectional study in the SecanggangDistrict, Lan gkat Regen cy of North Sumat era, from Augustto November 2009 in children aged 2 months to 14 years .Microscopic stool examination s were undertaken to separatesubjects into the acute bacterial or non-bacterial diarrhea groups.Both groups received 10 mg/day ofzinc sulphate for subjects aged<6 months or 20 mg/day for those aged 2:6 months for 10 days.Measurement of disease severity was based on the frequency ofdiarrhea (times/day) and the duration of diarrhea (hours) afterinitial drug consumption . We performed indepen dent T test forstatistical an alysis.Results Sixty-two children participated in this study, with 31children in the acute bacterial group, and the remainder in thenon-bacterial group. There were no significant differences betweenthe two gro ups in frequency of diarrhea (2 .61 vs 2.70 times/day,respectively, P=0.27) or in duration of diarrhea (63.39 vs 66.68hours, respectively, P= 0.06) .Conclusion Zinc is not more effective in reducing the severityof acute bacterial diarrhea compared to non-bacterial diarrhea inchildren.

2017 ◽  
Vol 145 (13) ◽  
pp. 2735-2744 ◽  
Author(s):  
J.-X. YU ◽  
W.-P. ZHU ◽  
C.-C. YE ◽  
C.-Y. XUE ◽  
S.-J. LAI ◽  
...  

SUMMARYDiarrhea is a common cause of morbidity and mortality and the incidence of diarrhea in the world has changed little over the past four decades. To assess the prevalence of and healthcare practices for diarrhea, a cross-sectional study was conducted in Pudong, Shanghai, China. In October 2014, a total of 5324 community residents were interviewed. Respondents were asked if they had experienced diarrhea (defined as ⩾3 passages of watery, loose, bloody, or mucoid stools within a 24-h period) in the previous month prior to the interview. The monthly prevalence of diarrhea was 4·1% (95% CI: 3·3–4·8), corresponding to an incidence rate of 0·54 episodes per person-year. The proportion of individuals with diarrhea who sought healthcare was 21·2% (95% CI: 13·4–29·0). Diarrhea continues to impose a considerable burden on the community and healthcare system in Pudong. Young age and travel were identified as predictors of increased diarrhea occurrence.


2021 ◽  
pp. 095646242110150
Author(s):  
Doreen Nabukalu ◽  
Matthew Ponticiello ◽  
Thomas Bennett ◽  
Sunday Clark ◽  
Rachel King ◽  
...  

Uptake of HIV testing is suboptimal in Uganda, particularly in rural communities. Reaching UNAIDS 95-95-95 goals requires strategies to increase HIV testing among hard-to-reach populations. This cross-sectional study sought to characterize engagement with HIV testing among traditional healers and their clients in rural Uganda. We enrolled 175 traditional healers and 392 adult clients of healers in Mbarara District. The primary outcome for this study was having received an HIV test in the prior 12 months. Most clients ( n = 236, 65.9%) had received an HIV test within 12 months, compared to less than half of healers ( n = 75, 46.3%) who had not. In multivariate regression models, male clients of healers were half as likely to have tested in the past year, compared with female (adjusted odds ratios (AORs) = 0.43, 95% CI = 0.26–0.70). Increasing age negatively predicted testing within the past year (AOR = 0.95, 95% CI = 0.93–0.97) for clients. Among healers, more sexual partners predicted knowing ones serostatus (AOR = 1.6, 95% CI 1.03–2.48). Healers (AOR = 1.16, 95% CI 1.07–1.26) and clients (AOR = 1.28, 95% CI 1.13–1.34 for clients) with greater numbers of lifetime HIV tests were more likely to have tested in the past year. Traditional healers and their clients lag behind UNAIDS benchmarks and would benefit from programs to increase HIV testing uptake.


2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Abdullah Alnajem ◽  
Abdullah Redha ◽  
Dalal Alroumi ◽  
Ahmed Alshammasi ◽  
Mohamad Ali ◽  
...  

Abstract Background Globally, a surge in electronic cigarette (e-cigarette) use has been observed in recent years, with youth being the most susceptible group. Given their recent emergence, studies assessing the health consequences of using e-cigarettes and exposure to their secondhand aerosols (SHA) are limited. Hence, this study sought to assess associations between e-cigarette use and household exposure to SHA from e-cigarettes with asthma symptoms among adolescents. Methods A school-based cross-sectional study was conducted by enrolling high school students (n = 1565; aged 16–19 years) in Kuwait. Participants self-completed a questionnaire on tobacco products use (e-cigarettes and cigarettes) and asthma symptoms. Current e-cigarette use and cigarette smoking were defined as any use in the past 30 days. Household exposure to SHA from e-cigarettes in the past 7 days was reported as none (0 days), infrequent (1–2 days), and frequent (≥ 3 days). Asthma symptoms included current (past 12 months) wheeze, current asthma (history of clinical diagnosis and current wheeze and/or medication use), and current symptoms of uncontrolled asthma (≥ 4 attacks of wheeze, ≥ 1 night per week sleep disturbance from wheeze, and/or wheeze affecting speech). Associations were assessed using Poisson regression with robust variance estimation, and adjusted prevalence ratios (aPRs) and 95% confidence intervals (CIs) were estimated. Results Among the analytical study sample (n = 1345), current e-cigarette use and cigarette smoking was reported by 369 (27.4%) and 358 (26.6%) participants, respectively. Compared to never e-cigarette users and never cigarette smokers, current e-cigarette users with no history of cigarette smoking had increased prevalence of current wheeze (aPR = 1.54, 95% CI 1.01–2.45) and current asthma (aPR = 1.85, 95% CI 1.03–3.41). Moreover, the frequency of exposure to household SHA from e-cigarettes was associated with asthma symptoms. For example, compared to those with no exposure to household SHA, frequent exposure to household SHA was associated with current wheeze (aPR = 1.30, 95% CI 1.04–1.59), current asthma (aPR = 1.56, 95% CI 1.13–2.16), and current uncontrolled asthma symptoms (aPR = 1.88, 95% CI 1.35–2.62). Conclusions E-cigarette use and their household SHA exposure were independently associated with asthma symptoms among adolescents. Hence, such observations indicate that e-cigarette use and passive exposure to their aerosols negatively impact respiratory health among adolescents.


2019 ◽  
Vol 8 (2) ◽  
pp. 76-80
Author(s):  
Sushila Lama Moktan ◽  
Ujma Shrestha ◽  
Mona Sharma ◽  
Manan Karki

Background: With the advent of anesthesia, surgery is no longer a race against the clock and surgeons. Many studies in the past have demonstrated limited knowledge among patients about various aspects of anesthesia.Objectives: To assess the awareness and concern of elective surgical patients towards anesthesia.Methodology: A cross-sectional questionnaire survey was conducted over two months’ period in adult patients of age eighteen years and above. Two hundred surgical patients accessing services at the pre-anesthesia check-up clinic were interviewed using 12 questions assessing demographic characteristics, educational status and their knowledge about anesthesia.Results: Out of 200 patients, only 32% knew that anesthesiologists provide anesthesia. It was found that 63% didn’t have any knowledge about the types of anesthesia. The most common fear among the participants about anesthesia was the fear of pain during surgery.Conclusion: The study showed poor knowledge of patients regarding anesthesia.


2019 ◽  
Vol 48 ◽  
Author(s):  
Glauco André MARQUES ◽  
Carolina Carmo de MENEZES ◽  
Giovana Cherubini VENEZIAN ◽  
José Fernando Castanha HENRIQUES ◽  
Silvia Amélia Scudeler VEDOVELLO ◽  
...  

Abstract Introduction This cross-sectional study aimed to associate the normative cephalometric results of mandibular retrognathism treatment with patient perception on the esthetic improvement of facial profile. Objective this cross-sectional study aimed to associate the normative cephalometric results of mandibular retrognathism treatment with patient perception on the esthetic improvement of facial profile. Material and method The normative cephalometric results were obtained from lateral cephalometric radiographs of a sample of 24 Class II malocclusion patients in the pubertal growth spurt. Such patients were treated with a mandibular advancement device and evaluated by comparing pre- and post-treatment variables. The same radiographs were used to produce standardized black silhouettes that were randomly arranged. Patients were instructed to choose their preferred profile and indicate the changes perceived using a 7-point Likert scale. The data were compared with cephalometric results using a mixed-model methodology for time-repeated measures, Student’s t-test, and t-test for heterogeneous variances, at 5% significance level. Result A rate of 75% of patients preferred post-treatment silhouettes and changes were perceived regardless of the choice of either pre- or post-treatment profile. There was no significant difference between the cephalometric variables of the tracings that produced the silhouettes considered better or worse after the evaluation. Conclusion There was no association between the cephalometric results after treatment and the perception of esthetic improvement by patients treated for mandibular retrognathia.


BMJ Open ◽  
2018 ◽  
Vol 8 (9) ◽  
pp. e021845 ◽  
Author(s):  
Yang Gao ◽  
Weicong Cai ◽  
Lijie Gao ◽  
Jingjing Wang ◽  
Jiehui Liang ◽  
...  

ObjectivesThis study aimed to investigate the epidemiological characteristics and preliminarily explore possible risk factors of physical activity-related injury (PARI) occurrences among Chinese university students via a multicentre mixed survey.DesignCross-sectional study.ParticipantsA total of 4758 undergraduates graded 1–3 in nine universities in three Chinese cities were enrolled via cluster random sampling and completed the self-administered online questionnaires during March and April 2017.Main outcome measuresPARI in the past 12 months.ResultsOf the 4758 participants, 1081 sustained PARI in the past 12 months, with an overall PARI incidence rate of 22.7% (27.3% (367/1343) in males and 20.9%(714/3415) in females). Around one-quarter of the injured (26.4%) suffered from PARI over at least three episodes. More than half of the injured subjects experienced physical activity (PA) absenteeism and sought medical attention. All PA indicators were significantly and positively associated with PARI, with a frequency of sports and leisure-time vigorous-intensity PA (VPA) participation being the strongest (adjusted OR: 1.079, 95% CI: 1.018 to 1.144). Moreover, males (OR=1.199), Shantou students (OR=4.239), year 1 students (OR=1.287), university and other sports team members (OR=1.717–2.360) and those with insufficient sleep time (OR=1.262–1.333) were also at a higher risk of PARI.ConclusionsPARI is prevalent among university students in China. The frequency of sports and leisure-time VPA participation was most strongly associated with PARI among all PA indicators. These data can inform future programmes for injury intervention among university students. Safety issues should also be emphasised when promoting PA among the public to reduce PARI.


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