Relationship between small for gestational age and aortic intima-media thickness in newborns

Background Small for gestational age (SGA) has been associatedwith adult cardiovascular disease. Small for gestational agenewborns may undergo early aortic wall intima-media thickening(aIMT) in utero.Objective To determine the relationship between SGA as a riskfactor for increased aIMT, as a sign of atherosclerosis onset.Methods We conducted a case-control study in the Neonatal Wardand Rooming-in Nursery at Dr. Mohammad Hoesin Hospital,Palembang, between April to June 2012. Subjects were allocatedto either the case group (aIMT 2: 0.9 mm) or to the controlgroup (aIMT <0.9 mm). Newborns were classified as SGA iftheir birthweight (BW) was < l O'h percentile, and appropriatefor gestational age (AGA) if their BW was between lQth - 90'hpercentile, according to the Lubchenco curve. Abdominal aorticintima-media thickness was measured by echocardiographyexamination.Results The case and control groups consisted of 30 n ewbornseach. The proportion of SGA newborns was higher in the casegroup than the control group. The likelihood of infants in the casegroup being SGA was significantly higher compared to the controlgroup, with odds ratio of 10.8 (95%CI 3,26 to 35, 72) . The meanaIMT was significantly higher in SGA than in AGA infants, 0.9(SD 0.16) mm vs. 0.8 (SD 0.13) mm, respectively, with a meandifference of 0, 13 (9 5% CI 0, 050 to 0,209 mm; P"" 0,02).Conclusion Increased aIMT is more likely found in SGA newborns.

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Relationship between small for gestational age and aortic intima-media thickness in newborns

Paediatrica Indonesiana ◽

10.14238/pi53.1.2014.10 ◽

2014 ◽

Vol 54 (1) ◽

pp. 57-61

Author(s):

Ahmad Bayu Alfarizi ◽

Ria Nova ◽

Julniar Mawardi Tasli ◽

Theodorus Theodorus

Keyword(s):

Gestational Age ◽

Small For Gestational Age ◽

Intima Media Thickness ◽

Media Thickness ◽

Aortic Intima

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OP31.02: Aortic intima media thickness in twin pregnancies affected by selective intrauterine growth restricted and small for gestational age co-twin

Ultrasound in Obstetrics and Gynecology ◽

10.1002/uog.9546 ◽

2011 ◽

Vol 38 (S1) ◽

pp. 145-146

Author(s):

S. Visentin ◽

V. Zanardo ◽

D. Trevisanuto ◽

F. Grumolato ◽

S. Vedovato ◽

...

Keyword(s):

Gestational Age ◽

Small For Gestational Age ◽

Intima Media Thickness ◽

Intrauterine Growth ◽

Media Thickness ◽

Aortic Intima ◽

Twin Pregnancies

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Thoracic Aortic Intima-Media Thickness in Preschool Children Born Small for Gestational Age

The Journal of Pediatrics ◽

10.1016/j.jpeds.2018.12.037 ◽

2019 ◽

Vol 208 ◽

pp. 81-88.e2 ◽

Cited By ~ 2

Author(s):

Manoel Muñiz Fontán ◽

Ignacio Oulego Erroz ◽

Daniela Revilla Orias ◽

Ana Muñoz Lozón ◽

Antonio Rodriguez Núñez ◽

...

Keyword(s):

Preschool Children ◽

Gestational Age ◽

Small For Gestational Age ◽

Intima Media Thickness ◽

Media Thickness ◽

Aortic Intima

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Aortic Intima-Media Thickness and Aortic Diameter in Small for Gestational Age and Growth Restricted Fetuses

PLoS ONE ◽

10.1371/journal.pone.0126842 ◽

2015 ◽

Vol 10 (5) ◽

pp. e0126842 ◽

Cited By ~ 14

Author(s):

M. Dolores Gomez-Roig ◽

Edurne Mazarico ◽

Esther Valladares ◽

Laura Guirado ◽

Mireia Fernandez-Arias ◽

...

Keyword(s):

Gestational Age ◽

Small For Gestational Age ◽

Intima Media Thickness ◽

Aortic Diameter ◽

Age And Growth ◽

Media Thickness ◽

Aortic Intima

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Association of Genetic Polymorphisms in FOXA1 with the Progression of Genetic Susceptibility to Gastric Cancer

Gastroenterology Research and Practice ◽

10.1155/2020/3075837 ◽

2020 ◽

Vol 2020 ◽

pp. 1-8 ◽

Cited By ~ 2

Author(s):

Guo-wen Ding ◽

Xu-yu Gu ◽

Zhe Dai ◽

Hui-wen Pan ◽

Xiao-yan Wang ◽

...

Keyword(s):

Gastric Cancer ◽

Target Gene ◽

Case Control Study ◽

Control Group ◽

Case Group ◽

Significant Difference ◽

Drinking Status ◽

And Control ◽

The Relationship ◽

Control Study

Objective. To investigate the relationship between polymorphism of FOXA1 gene rs12894364 and rs7144658 and susceptibility to gastric cancer. Methods. A case-control study was conducted to select 577 cases of primary gastric cancer and 678 cases of normal control. We extracted whole blood genomic DNA and amplified the target gene fragment by PCR. The genotyping and allele was tested through a snapshot method. Results. There was no significant difference in the frequency distribution of genotype between the case group and control group (P>0.05). Stratified analyses showed the SNPs were not correlated with the susceptibility of GC according to different age, gender, cigarette smoking, and alcohol drinking status. Conclusion. There is no significant correlation between the polymorphisms of FOXA1 gene rs12894364 and rs7144658 and the risk of gastric cancer.

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Prevalence of Generalized Joint Hypermobility in Children with Anxiety Disorders

10.21203/rs.2.22347/v1 ◽

2020 ◽

Author(s):

vadood javadi ◽

Shadi Sadat Modarres ◽

Ghazal Zahed ◽

Reza Shiari ◽

Khosro Rahmani

Keyword(s):

Anxiety Disorders ◽

Joint Hypermobility ◽

Child And Adolescent Psychiatry ◽

Control Group ◽

Case Group ◽

Generalized Joint Hypermobility ◽

High Prevalence ◽

And Control ◽

The Relationship ◽

Control Study

Abstract Background Concerning the high prevalence of anxiety disorders and joint hypermobility in children and the lack of related studies in this age group, we aimed to assess the relationship between the prevalence of hypermobility and anxiety disorders in children. MethodsIn this case-control study, 93 children ages 8-15 years with anxiety disorders referring to the Child and Adolescent Psychiatry Clinic of Mofid Children’s Hospital, Tehran, Iran, during 2018, were enrolled. The control group consisted of 100 age and sex-matched children without anxiety disorders. Anxiety was evaluated using the Spence Children Anxiety Scale (SCAS). The diagnosis of generalized joint hypermobility was done based on Beighton and Shiari-Javadi criteria. Results Based on Beighton’s diagnostic criteria 52.7% of the children in the case group and 16% of the children in the control group had generalized joint hypermobility. Moreover, based on Shiari-Javadi criteria, 49.5% and 13% of the children in the case and control groups had generalized joint hypermobility, respectively. Moreover, the internal correlation between the two criteria was 0.91 showing almost complete compatibility between the two (P<0.001). Age was a risk factor that could predict hypermobility in these children. Other variables such as sex, severity, and type of anxiety disorders, and ADHD, were not predictors of hypermobility syndrome. Conclusion The prevalence of hypermobility was three times higher in children with anxiety disorders and only age was a predictor for the possibility to suffer from generalized joint hypermobility in these children.

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The correlation between family smoking habits and mosquito coils use with pneumonia incidences in toddlers

Journal of Health Technology Assessment in Midwifery ◽

10.31101/jhtam.740 ◽

2019 ◽

Vol 2 (2) ◽

pp. 69-74

Author(s):

Wiwin Winarsih ◽

Wiwik Kusumawati ◽

Anjarwati Anjarwati

Keyword(s):

Smoking Habits ◽

Observational Research ◽

Control Group ◽

P Value ◽

Case Group ◽

Chi Square ◽

Study Approach ◽

The Family ◽

The Relationship ◽

Control Study

The incidences of pneumonia in infants Become the second highest cause mortality before reaching the age of 5 years and a health problem in Indonesia. The family of smoking and smoke from burning mosquito coils are the triggers for air pollution, which can lead to pneumonia in infants. The study aims to analyze the relationship between family smoking habits and the use of mosquito coils with the incidence of pneumonia in under-fives. The method of research applied analytic observational research using a case-control study approach. The number of samples in this study was 87 under-fives in the case group and 87 under-fives in the control group. Sampling was conducted by non-probability sampling. A questionnaire was used as a data collecting instrument. Data analysis used chi-square and multiple logistic regression. The results of this study Showed that there was a relationship between family smoking habits and the use of mosquito coils with the incidence of pneumonia in infants. In addition, there were other variables that had a relationship with the incidence of pneumonia in under-fives namely smoking location (OR = 3,046; 95% CI: 1429-6492, p = 0.003), the number of cigarettes (OR = 7.105 ; 95% CI: 3079-16394, p = 0.000), and length of time with smokers (p = 0.000). On the other hand, the variables of father smoker status and the frequency of using mosquito coils were not related to the incidence of pneumonia in under-fives (p value 0.05). It is concluded that family smoking habits, use of mosquito coils, the location of smoking, and number of cigarettes, and length of time together with smokers were risk factors associated with the incidence of pneumonia in toddlers

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Visfatin Levels May be an Early Marker of Atherosclerosis in Patients with Acromegaly

Hormone and Metabolic Research ◽

10.1055/a-0998-4079 ◽

2019 ◽

Vol 51 (10) ◽

pp. 649-654

Author(s):

Hamide Piskinpasa ◽

Yildiz Okuturlar ◽

Sema Ciftci Dogansen ◽

Yasemin Sefika Akdeniz ◽

Ayse Esen ◽

...

Keyword(s):

Ankle Brachial Index ◽

Intima Media Thickness ◽

Carotid Intima Media Thickness ◽

Control Group ◽

Healthy Controls ◽

Cross Sectional ◽

Normal Ratio ◽

Visfatin Level ◽

And Control ◽

Control Study

AbstractThe purpose of the study was to compare serum visfatin levels between patients with acromegaly and healthy controls and to evaluate the relationships between visfatin levels and epicardial fat thickness (EFT), carotid intima media thickness (cIMT), and ankle brachial index (ABI). We conducted a cross-sectional case-control study of 54 patients with acromegaly (37 females and 17 males) and 34 healthy controls (22 females and 12 males). Serum visfatin was measured by ELISA. Acromegalic and control participants and those with active or controlled acromegaly were compared with respect to their serum visfatin, clinical and metabolic parameters, EFT, cIMT, and ABI. Linear correlation was used to identify associations between these parameters and visfatin in all participants. Serum visfatin and glycated hemoglobin (HbA1c) were higher in the acromegaly group than in the control group (p<0.001 and p=0.007, respectively). There was no difference in visfatin between the active and controlled acromegaly groups, but HbA1c was higher in the active than the controlled acromegaly group (p<0.04). EFT, cIMT, and ABI were similar between the acromegaly and control groups and between the active and controlled acromegaly groups. Serum visfatin positively correlated with HbA1c, growth hormone (GH), and insulin-like growth factor-1 (IGF-1)/upper limit of normal ratio (r=0.245, p=0.024; r=0.259, p=0.017; and r=0.282, p=0.009, respectively). This study has revealed that a high visfatin level is associated with glycemic dysregulation and higher levels of GH and IGF-1 in acromegalic patients.

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