scholarly journals An Inexpensive, Portable, and Versatile Electronic Nose for Illness Detect

Author(s):  
F. Riscica ◽  
E. Dirani ◽  
A. Accardo ◽  
A.I. Chapoval

Health-care strategies are currently oriented towards non-invasive techniques for an early diagnosis. The chemical analysis seems to be a good answer to accomplish both prevention, a fundamental requirement for an efficient treatment of the disease, and non-invasivity. GC is very accurate but is expensive; its sampling and assaying processes are complicated and time consuming, while its results require expert interpretation. Over the last decade, "electronic sensing" or "e-sensing" technologies have undergone some important developments from both a technical and commercial point of view. Particularly, in recent years, the usefulness of the electronic nose has been clinically proved as an opportunity for the early detection of such diseases as lung cancer, diabetes, and tuberculosis. In this paper, a portable, versatile and inexpensive system for the measurement of gas concentration through a gas sensor array is described. The system uses low cost metal oxide gas transducers and can automatically compensate the values of gas concentration detected according to the current values of temperature and humidity. The device works in slave mode and its acquired and computed data are available by means of a host/slave ASCII serial communication protocol. A host device can periodically require the current values of gas concentration and apply the appropriate algorithms for the detection of the investigated substances.

2015 ◽  
Vol 74 (6) ◽  
Author(s):  
Syarifah Noor Syakiylla Sayed Daud ◽  
Rubita Sudirman

There has been a lot of research on the study of the human brain. Many modalities such as medical resonance imaging (MRI), computerized tomography (CT), positron emission tomography (PET), electroencephalography (EEG) and etc. has been invented. However, between this modality the electroencephalography widely chosen by researchers due to it is low cost, non-invasive techniques, and safely use. One of the major problems, the signal is corrupted by artifacts, whether to come from the muscle movement (electromyography artifact), eye blink and movement (electrooculography artifact) and power line interference. Filtering technique is applied to the signal in order to remove these artifacts. Wavelet approach is one of the technique that can filter out the artifact. This paper aim to determine which decomposition level is suitable for filtering EEG signal at channel Fp1, Fz, F8, Pz, O1 and O2 use stationary wavelet transform filter at db3 mother wavelet. Eight different decomposition levels have been selected and analyze based on mean square error (MSE) parameter. The Neurofax 9200 was used to record the brain signal at selected channel. Result shows that the decomposition at level 5 is suitable for filtering process using this stationary wavelet transform approach without losing important information.


2015 ◽  
Vol 771 ◽  
pp. 50-54 ◽  
Author(s):  
Kuwat Triyana ◽  
M. Taukhid Subekti ◽  
Prasetyo Aji ◽  
Shidiq Nur Hidayat ◽  
Abdul Rohman

A portable electronic nose (e-nose) using low-cost dynamic headspace and commercially metal oxide gas sensors has been developed. This paper reports evaluation on the performance of the e-nose to classify vegetable oils (sunflower and grape seed oils) and animal fats (mutton, chicken and pig fats). The e-nose consists of a dynamic headspace sampling, a gas sensor array and a real-time data acquisition system based on ATMega-16 microcontroller. The dynamic headspace can divided into two chambers, i.e. sample and gas sensor array room. It is also equipped with three small fans for adjusting sensing and purging processes. Principal component analysis (PCA) was used for measurement data analysis after all features being extracted. The first two principal components were kept because they accounted for 91.1% of the variance in the data set (first and second principals accounted for 72.9, 18.2% of the variance, respectively). This results show that the e-nose can distinguish vegetable oils and animal fats. This work demonstrates for the future that the e-nose with low-cost dynamic headspace technique may be applied to the identification of oils and fats in halal authentication.


Smell and Taste are the two very imperative senses which enable us in detection and discrimination of several volatile organic compounds, which in turn may be identified as indicators for specific desirable or undesirable conditions in various industries. Electronic nose and electronic tongue are recent technologies which have attracted many researchers to work in order to provide effective solutions for various industrial applications. This paper overviews the functionality of the electronic nose and electronic tongue and presents a summary of different sensors used for the said technologies. Also, a comparison between an E-nose and E-tongue is presented on the basis of relative figure of merits. A case study is presented wherein application of artificial nose and artificial tongue is discussed for the quality analysis of the fruits. The paper is aimed to emphasis on the possibilities of combining e-nose and e-tongue techniques to enhance the overall performance of the system used for food quality analysis. An E-nose combined with an E-tongue can be a highly efficient, non-invasive, fast and low cost method of quality analysis that can serve the industry and society for the betterment of the mankind


Sensor Review ◽  
2017 ◽  
Vol 37 (2) ◽  
pp. 165-171 ◽  
Author(s):  
Krishna Chandra Persaud

Purpose The purpose of this paper is to review recent progress in electronic nose technologies, focusing on hybrid systems combining biological elements with physical transducers. Design/methodology/approach Electronic nose technologies are moving rapidly towards hybrid bioelectronic systems, where biological odour-recognition elements from the olfactory pathways of vertebrates and insects are being utilised to construct new “bionic noses” that can be used in industrial applications. Findings With the increased understanding of how chemical senses and the brain function in biology, an emerging field of “neuromorphic olfaction” has arisen. Research limitations/implications Important components are olfactory receptor proteins and soluble proteins found at the periphery of olfaction called odorant-binding proteins. The idea is that these proteins can be incorporated into transducers and function as biorecognition elements for volatile compounds of interest. Practical implications Major drivers are the security, environmental and medical applications, and the internet of things will be a major factor in implementing low-cost chemical sensing in networked applications for the future. Social implications Widespread take up of new technologies that are cheap will minimise the impact of environmental pollution, increase food safety and may potentially help in non-invasive screening for medical ailments. Originality/value This review brings together diverse threads of research leading to a common theme that will inform a non-expert of recent developments in the field.


2017 ◽  
Vol 37 (3) ◽  
pp. 45-51
Author(s):  
Ana R. Correa ◽  
Martha M. Cuenca ◽  
Carlos M. Zuluaga ◽  
Matteo M. Scampicchio ◽  
Marta C. Quicazán

Honey is a natural sweetener and its quality labels are associated to its botanical or geographical origin, which is being established by palynological and sensorial analysis. The use of fast and non-invasive techniques such as an electronic nose can become an alternative for honey classification. In this study, the operational parameters of a commercial electronic nose were validated to determine the honey odor profile. A central composite design with five factors, three levels and 28 assays was used, varying sample amounts (1, 2 and 3 g), incubation temperature (30, 40 and 50 °C), incubation time 30 min), gas flow (50, 150 and 250 mL/min) and injection time (100, 200 and 300 s). The commercial nose had ten sensors. Repeatability was evaluated with a coefficient of variation of 10 %. The response surface methodology was used and the optimal operating conditions were: 3 g of sample, incubation at 50 °C for 17 min, gas flow of 100 mL/min and sampling time of 150 s. Finally, these parameters were used to analyze 19 samples of honey, which were classified according to their odor profiles, showing that it can be a useful tool to classify honey.


2020 ◽  
Vol 10 (14) ◽  
pp. 4804
Author(s):  
Giovanni Dimauro ◽  
Danilo Caivano ◽  
Pierangelo Di Pilato ◽  
Alessandro Dipalma ◽  
Mauro Giuseppe Camporeale

Contribution: This paper examines the literature dealing with the non-invasive estimate of anemia (NEA), and analyzes if the research is developing scientifically with adequate empirical validation. This paper reveals a trend in NEA studies towards an increasing interest in estimating anemia using conjunctiva pallor. Background: Supporting clinical developments and processes to reduce personal discomfort and allow extensive screening needs substantial efforts in researching non-invasive techniques to evaluate anemia. Research Questions: The main aims of this study are the analysis of the area of interest explored in the NEA literature, the evaluation of the peculiarities of papers, giving special consideration to empirical ones, examining them from the point of view of the daily improvement of doctors and healthcare personnel activities and the daily life of patients; and the identification of any considerable research gap to encourage further investigations on new topics. Methodology: The systematic mapping study has been elected as the optimal approach to probe the NEA literature since it defines a rigorous process for data retrieving and interpretation. Findings: Research in this sector is very active, especially in the most populated countries in the world and focuses on improving the technologies currently on the market and on proposing new solutions, especially portable and usable by everyone. A new trend in camera and smartphone-based devices is identified.


Lontara ◽  
2020 ◽  
Vol 1 (1) ◽  
pp. 41-50
Author(s):  
Usman Umar ◽  
Risnawaty Alyah

Gout or gout arthritis is a disease caused by the accumulation of monosodium uric crystals in the body. Uric acid is the result of the final metabolism of purines, which is a component of nucleic acids found in the body's cell nucleus. Increased uric acid can cause disturbances in the human body such as feelings of pain. The standard system used to measure uric acid levels in the blood, in general, is an invasive system that uses blood samples and is performed in clinics, health centers, and hospitals at a high cost. This research aims to develop a non-invasive system measuring gout using Near Infrared (NIR) sensor with 940 nm LED and Photodiode as a detector at a wavelength range of 600-1300 nm. The method of developing this tool begins with the stages, conducting a literature study resulting in tool design and tool making as well as tool validation by comparing invasive and non-invasive techniques. The results of this study produce a simple gout monitoring tool with an error value of 4% and low cost and easy to use. Analysis of the results of the tests using analysis of variance P-value> 0.05 and the t-test P (T <= t) 0.45> α shows that the tool designed can be used to monitor gout.


2020 ◽  
Vol 158 (6) ◽  
pp. S-1249
Author(s):  
Yuri Hanada ◽  
Juan Reyes Genere ◽  
Bryan Linn ◽  
Tiffany Mangels-Dick ◽  
Kenneth K. Wang

2019 ◽  
Vol 19 (2) ◽  
pp. 105-111
Author(s):  
Nadia Shafei ◽  
Mohammad Saeed Hakhamaneshi ◽  
Massoud Houshmand ◽  
Siavash Gerayeshnejad ◽  
Fardin Fathi ◽  
...  

Background: Beta thalassemia is a common disorder with autosomal recessive inheritance. The most prenatal diagnostic methods are the invasive techniques that have the risk of miscarriage. Now the non-invasive methods will be gradually alternative for these invasive techniques. Objective: The aim of this study is to evaluate and compare the diagnostic value of two non-invasive diagnostic methods for fetal thalassemia using cell free fetal DNA (cff-DNA) and nucleated RBC (NRBC) in one sampling community. Methods: 10 ml of blood was taken in two k3EDTA tube from 32 pregnant women (mean of gestational age = 11 weeks), who themselves and their husbands had minor thalassemia. One tube was used to enrich NRBC and other was used for cff-DNA extraction. NRBCs were isolated by MACS method and immunohistochemistry; the genome of stained cells was amplified by multiple displacement amplification (MDA) procedure. These products were used as template in b-globin segments PCR. cff-DNA was extracted by THP method and 300 bp areas were recovered from the agarose gel as fetus DNA. These DNA were used as template in touch down PCR to amplify b-globin gen. The amplified b-globin segments were sequenced and the results compared with CVS resul. Results: The data showed that sensitivity and specificity of thalassemia diagnosis by NRBC were 100% and 92% respectively and sensitivity and specificity of thalassemia diagnosis by cff-DNA were 100% and 84% respectively. Conclusion: These methods with high sensitivity can be used as screening test but due to their lower specificity than CVS, they cannot be used as diagnostic test.


2020 ◽  
Vol 16 (2) ◽  
pp. 138-152
Author(s):  
Bingren Zhang ◽  
Chu Wang ◽  
Chanchan Shen ◽  
Wei Wang

Background: Responses to external emotional-stimuli or their transitions might help to elucidate the scientific background and assist the clinical management of psychiatric problems, but pure emotional-materials and their utilization at different levels of neurophysiological processing are few. Objective: We aimed to describe the responses at central and peripheral levels in healthy volunteers and psychiatric patients when facing external emotions and their transitions. Methods: Using pictures and sounds with pure emotions of Disgust, Erotica, Fear, Happiness, Neutral, and Sadness or their transitions as stimuli, we have developed a series of non-invasive techniques, i.e., the event-related potentials, functional magnetic resonance imaging, excitatory and inhibitory brainstem reflexes, and polygraph, to assess different levels of neurophysiological responses in different populations. Results: Sample outcomes on various conditions were specific and distinguishable at cortical to peripheral levels in bipolar I and II disorder patients compared to healthy volunteers. Conclusions: Methodologically, designs with these pure emotions and their transitions are applicable, and results per se are specifically interpretable in patients with emotion-related problems.


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