Covid-19 in Gravid Uterus – The Challenge in Antenatal Care and Its Outcome – A Tertiary Level Cross Sectional Analysis from Chennai, India

BACKGROUND With the emerging pandemic of corona virus disease 19 (Covid-19) infection around the world, the need to identify the course of this disease in pregnant women becomes the need of the hour. Its effect on pregnancy and the neonatal outcome is not well known because of lack of any reliable data. We wanted to evaluate the clinical features, laboratory manifestations and obstetric outcome of Covid-19 in the term of antenatal mothers who were either admitted in labour, induction of labour or elective caesarean section and rule out vertical transmission by doing a routine neonatal screening for Covid-19. METHODS A descriptive cross-sectional study conducted at Sri Ramachandra Medical College & Research Institute, Chennai from March 2020 to September 2020 includes all antenatal women who were tested positive for severe acute respiratory syndrome (SARS- Cov2) reverse transcription - polymerase chain reaction (RT-PCR). 43 Covid positive patients were included in the study. RESULTS Incidence of Covid positive antenatal women was found to be 1.7 %. Only 3 % were symptomatic with mild disease. Gestational diabetes mellitus accounted for (27 %), Class II obesity (7 %), hypertensive disorders of pregnancy (13 %) of the screen positive mothers. 20 % of the labouring women had meconium-stained liquor. Lymphopenia was seen in 73 % of cases. Elevated d-dimer in 13 %, requiring thromboprophylaxis. Negative RT-PCR for SARS-CoV-2 in the neonates ruled out vertical transmission. CONCLUSIONS Covid-19 in pregnancy is more common in those with gestational diabetes, obesity, with development of complications like hypertension and meconium-stained liquor. The impact of Covid-19 is not as disabling as it is in the non-pregnant population. KEY WORDS Universal Screening, In/Near Labour, Lymphopenia, Thromboprophylaxis, Meconium- Stained Amniotic Fluid.

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Prevalence of SARS-CoV-2 Infection at the University of Barcelona during the Third COVID-19 Pandemic Wave in Spain

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18126526 ◽

2021 ◽

Vol 18 (12) ◽

pp. 6526

Author(s):

Sebastián Videla ◽

Aurema Otero ◽

Sara Martí ◽

M. Ángeles Domínguez ◽

Nuria Fabrellas ◽

...

Keyword(s):

Ad Hoc ◽

Venous Blood ◽

Herd Immunity ◽

Cross Sectional Study ◽

Rt Pcr ◽

Igg Antibody ◽

Cross Sectional ◽

Total Prevalence ◽

The University ◽

The Impact

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic started in December 2019 and still is a major global health challenge. Lockdown measures and social distancing sparked a global shift towards online learning, which deeply impacted universities’ daily life, and the University of Barcelona (UB) was not an exception. Accordingly, we aimed to determine the impact of the SARS-CoV-2 pandemic at the UB. To that end, we performed a cross-sectional study on a sample of 2784 UB members (n = 52,529). Participants answered a brief, ad hoc, online epidemiological questionnaire and provided a nasal swab for reverse transcription polymerase chain reaction (RT-PCR) SARS-CoV-2 analysis and a venous blood sample for SARS-CoV-2 IgG antibody assay. Total prevalence of SARS-CoV-2 infection (positive RT-PCR or positive IgG) was 14.9% (95%CI 13.3 to 17.0%). Forty-four participants (1.6%, 95%CI: 1.2–2.1%) were positive for SARS-CoV-2 RT-PCR. IgG against SARS-CoV-2 was observed in 12.8% (95%CI: 11.6–14.1%) of participants. Overall, while waiting for population vaccination and/or increased herd immunity, we should concentrate on identifying and isolating new cases and their contacts.

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Variation in performance on common content items at UK medical schools

BMC Medical Education ◽

10.1186/s12909-021-02761-1 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

David Hope ◽

David Kluth ◽

Matthew Homer ◽

Avril Dewar ◽

Richard Fuller ◽

...

Keyword(s):

Undergraduate Students ◽

Standard Setting ◽

Medical Schools ◽

Cross Sectional Study ◽

Pass Rates ◽

Cross Sectional ◽

Study Results ◽

Institutional Differences ◽

Common Content ◽

The Impact

Abstract Background Due to differing assessment systems across UK medical schools, making meaningful cross-school comparisons on undergraduate students’ performance in knowledge tests is difficult. Ahead of the introduction of a national licensing assessment in the UK, we evaluate schools’ performances on a shared pool of “common content” knowledge test items to compare candidates at different schools and evaluate whether they would pass under different standard setting regimes. Such information can then help develop a cross-school consensus on standard setting shared content. Methods We undertook a cross-sectional study in the academic sessions 2016-17 and 2017-18. Sixty “best of five” multiple choice ‘common content’ items were delivered each year, with five used in both years. In 2016-17 30 (of 31 eligible) medical schools undertook a mean of 52.6 items with 7,177 participants. In 2017-18 the same 30 medical schools undertook a mean of 52.8 items with 7,165 participants, creating a full sample of 14,342 medical students sitting common content prior to graduation. Using mean scores, we compared performance across items and carried out a “like-for-like” comparison of schools who used the same set of items then modelled the impact of different passing standards on these schools. Results Schools varied substantially on candidate total score. Schools differed in their performance with large (Cohen’s d around 1) effects. A passing standard that would see 5 % of candidates at high scoring schools fail left low-scoring schools with fail rates of up to 40 %, whereas a passing standard that would see 5 % of candidates at low scoring schools fail would see virtually no candidates from high scoring schools fail. Conclusions Candidates at different schools exhibited significant differences in scores in two separate sittings. Performance varied by enough that standards that produce realistic fail rates in one medical school may produce substantially different pass rates in other medical schools – despite identical content and the candidates being governed by the same regulator. Regardless of which hypothetical standards are “correct” as judged by experts, large institutional differences in pass rates must be explored and understood by medical educators before shared standards are applied. The study results can assist cross-school groups in developing a consensus on standard setting future licensing assessment.

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The Impact of Covid-19 Pandemic on Students’ Learning Outcome in Higher Education

AL-ISHLAH: Jurnal Pendidikan ◽

10.35445/alishlah.v13i2.974 ◽

2021 ◽

Vol 13 (2) ◽

pp. 1425-1431

Author(s):

Andi Rahman

Keyword(s):

Higher Education ◽

Learning Outcomes ◽

Online Teaching ◽

Teaching And Learning ◽

Human Life ◽

Cross Sectional ◽

Study Results ◽

Institute Of Technology ◽

The Impact ◽

Academic Year

The current Covid-19 pandemic has had many effects on human life globally, including the implementation of education. This study aimed to obtain the impact of the Covid-19 pandemic on learning outcomes in higher education. The research method used is a cross-sectional study. The data were taken from the test results at the end of the lecture, observations, and interviews. The research was conducted at the University of Muhammadiyah Lampung, IPDN Jatinangor Campus, and the Ahmad Dahlan Institute of Technology and Business, with 120 students participating. The data analysis technique used the percentage technique and cross-tabulation. The study results concluded that student learning outcomes decreased in the 2020-2021 academic year compared to the 2019-2020 academic year. The decline in learning outcomes includes knowledge, skills, and psychology. This finding has implications for the understanding of education personnel regarding online teaching and learning design during the Covid-19 pandemic.

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Risk factor for gestational diabetes mellitus and impact of gestational diabetes mellitus on maternal and fetal health during the antenatal period

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20213169 ◽

2021 ◽

Author(s):

Uma Jain ◽

Kusumlata Singhal ◽

Shikha Jain ◽

Deepali Jain

Keyword(s):

Diabetes Mellitus ◽

Risk Factors ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Congenital Malformation ◽

Fetal Health ◽

Antenatal Period ◽

Study Results ◽

History Of ◽

The Impact

Background: Gestational diabetes mellitus (GDM) is defined as any degree of dysglycaemia that occurs for the first time or is first detected during pregnancy. The adverse effects of GDM on pregnant women are pre-eclampsia, PIH, PPH, polyhydramanios, PROM, meanwhile, there would be an increase in dystocia, birth injury, and cesarean sectionMethods: This retrospective study was conducted in a Gynecology clinic in District Shivpuri to find out the various risk factors for GDM and to evaluate the impact of GDM on maternal and fetal health during the antenatal period. 84 patients who were diagnosed with GDM were included in the study. Results: Among risk factors; BMI >25 kg/m2 before pregnancy was found in 15.47% of the case, family history of diabetes mellitus 8.33%, Previous history of macrosomia 17.85%, Poor reproductive history 17.85%, baby with congenital malformation 8.33%, H/o unexplained IUFD 11.90%. H/o polyhydramnios 15.47%. History of PCOS 13.09% and preeclampsia was found in 17.85% of cases. In antenatal complications; miscarriages was found in 15.47%. polyhydramnios in 17.85%. Oligohydramnios in 8.33%, preterm labor in 11.90%, PROM in 9.52%, pre-eclampsia in 17.85%, sudden IUFD in 8.33% and congenital malformation was found in 4.76% of cases. On USG; IUGR was found in 7.14% of cases. Large for date fetus in 16.66% of cases and the normal growth was found in 76.19% of cases.Conclusions- In conclusion appropriate and timely diagnosis and treatment of GDM will result in decreased maternal and neonatal adverse outcomes comparable to general population rates, therefore, early diagnosis is important.

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Influence of COVID-19 on the Mental Health of Nurses dealing with COVID-19 Patients (A Study on Nurses within Karachi)

10.53350/pjmhs211551200 ◽

2021 ◽

Vol 15 (5) ◽

pp. 1200-1204

Author(s):

U. Amen ◽

Z. Rajwani ◽

U. Sumayya ◽

R. Haroon ◽

N. Mushtaq ◽

...

Keyword(s):

Mental Health ◽

Psychological Distress ◽

Preventive Intervention ◽

Cross Sectional Study ◽

Depression Anxiety Stress Scale ◽

Cross Sectional ◽

Moderate Depression ◽

Study Results ◽

The Impact ◽

Severe Anxiety

Background: Globally Corona virus (COVID-19) has become a huge challenge for all of the population. In South Asia, country Pakistan city Karachi the 1st case of this breakdown was identified on 26th February 2020 (Waris et al., 2020). This disease has developed psychological distress among all the population. COVID virus is one of the leading threats to all the healthcare organizations and due to increase rate of patients day by day, it has given enormous burden to all healthcare workers especially nurses the front line fighters who are always ready to give care towards the patient whom they encountered so it’s very crucial part to assess the impact of COVID -19 on the mental health of the nurses. Objective: The objective of the study is to identify the frequency level of stress, anxiety and depression among nurses while dealing with those patients who were admitted in various hospitals in Karachi for treatment of COVID-19. Method: A cross-sectional study was conducted from 20th November to 31st December 2020 from different hospitals in Karachi, Pakistan. Those Registered nurses who were assigned in isolation ward of Covid-19 were the part of the study. For data collection survey form was designed based on Depression Anxiety Stress scale (DASS-21) scale (Lovibond & Lovibond 1995). Results: The total mean score of depression among nurses was 50 (68%), Anxiety was 32 (43%) and stress was 34 (46%). 50 nurses suffered from moderate depression, 24 nurses reported from extremely severe anxiety and 50 nurses suffered from moderate stress level. From 74 participants 41(55.4%) were females and 33 (44.6%) were males. Furthermore, it shows that 25 (76%) males and 25 (61%) females suffered from moderate depression, 32 nurses 14 (42%) male and 18(43.90%) females reported from extremely severe anxiety. Conclusion: This pandemic is highly complex, contagious and vulnerable. The study results portrait that nurses working with COVID-19 patients have affected a lot of various psychological distress such as anxiety, stress, and depression. It is very vital for higher management to take major steps and take preventive intervention which would be beneficial towards their mental health in decreasing negative psychological outcomes, because they all are working under pressure environment. Key Words: Stress, Anxiety, Depression, Pandemic, Registered Nurse

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Impact of COVID-19 Lockdown Measures on Spanish People with Chronic Pain: An Online Study Survey

Journal of Clinical Medicine ◽

10.3390/jcm9113558 ◽

2020 ◽

Vol 9 (11) ◽

pp. 3558

Author(s):

Rubén Nieto ◽

Rebeca Pardo ◽

Beatriz Sora ◽

Albert Feliu-Soler ◽

Juan V. Luciano

Keyword(s):

Chronic Pain ◽

Online Survey ◽

Job Insecurity ◽

Virus Disease ◽

Cost Effective ◽

Psychosocial Health ◽

Management Style ◽

Cross Sectional ◽

Sleeping Problems ◽

The Impact

The corona virus disease 2019 (COVID-19) pandemic is one of the most important healthcare and societal challenges to have emerged in the last century. It may have effects on both physical and psychosocial health, but studies considering the impact on vulnerable populations, such as people with chronic pain, are needed. In this cross-sectional study, an online survey of relevant chronic pain domains, coping strategies, triggers and potential related variables was answered by 502 Spanish individuals with chronic pain. Participants were mainly women (88%) with longstanding chronic pain and moderate to high pain intensity and disability. The perception of pain aggravation and the most pain-related outcomes were observed. Contextual variables such as job insecurity, worries about the future, people cohabiting, being close to someone who had passed away, or being potentially infected with COVID-19 were related to worse outcomes. More than half the participants altered their pain management style (e.g., increased medication intake) and several changes occurred with respect to pain triggers (cognitions, feelings of insecurity and loneliness, and sleeping problems were more frequently reported as triggers during lockdown). Our preliminary results highlight the negative effects of lockdown on patients with chronic pain as well as the need to make available cost-effective and remotely accessible healthcare resources for counteracting them.

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Association of the combination of weight gain after 20 years of age and current obesity with chronic kidney disease in Japan: a cross-sectional study

BMJ Open ◽

10.1136/bmjopen-2018-027752 ◽

2019 ◽

Vol 9 (6) ◽

pp. e027752

Author(s):

Hirotaka Ochiai ◽

Takako Shirasawa ◽

Takahiko Yoshimoto ◽

Satsue Nagahama ◽

Mariko Kobayashi ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Weight Gain ◽

Kidney Disease ◽

Cross Sectional Study ◽

Primary Outcome Measure ◽

Sectional Study ◽

Cross Sectional ◽

Study Results ◽

Obese Subjects ◽

The Impact

ObjectivesWeight gain after 20 years of age is associated with chronic kidney disease (CKD). However, the impact of weight gain on CKD might differ by current obesity status. We investigated the association of the combination of weight gain after 20 years of age and current obesity with CKD among adults in Japan.DesignA cross-sectional study.Setting and participantsWe analysed data from 94 822 adults aged 40–64 years who had an annual health check-up in Japan from April 2013 to March 2014.Primary outcome measureCKD was defined as an estimated glomerular filtration rate <60 mL/min/1.73 m2and/or proteinuria.ResultsBoth weight gain ≥10 kg after 20 years of age plus obesity (OR 2.21, 95% CI 2.07 to 2.36) and weight gain of ≥10 kg plus non-obesity (OR 1.31, 95% CI 1.21 to 1.42) significantly increased the OR for CKD when compared with weight gain <10 kg plus non-obesity in men. In women, weight gain ≥10 kg plus obesity (OR 2.04, 95% CI 1.84 to 2.25) and weight gain ≥10 kg plus non-obesity (OR 1.53, 95% CI 1.36 to 1.72) significantly increased the OR for CKD compared with weight gain <10 kg plus non-obesity. These results persisted even after adjustment for age, lifestyle factors, hypertension, dyslipidaemia and diabetes.ConclusionsWeight gain ≥10 kg after 20 years of age was significantly associated with CKD in both obese and non-obese subjects. Moreover, the influence of weight gain ≥10 kg plus obesity on CKD was greater than that of weight gain ≥10 kg plus non-obesity on CKD. The present study results suggest that it is important to consider weight gain after maturity in both obese and non-obese subjects to prevent CKD among Japanese middle-aged adults.

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The Global Impact of COVID-19 on Craniomaxillofacial Surgeons

Craniomaxillofacial Trauma & Reconstruction ◽

10.1177/1943387520929809 ◽

2020 ◽

Vol 13 (3) ◽

pp. 157-167 ◽

Cited By ~ 2

Author(s):

Justin van der Tas ◽

Thomas Dodson ◽

Daniel Buchbinder ◽

Stefano Fusetti ◽

Michael Grant ◽

...

Keyword(s):

Virus Disease ◽

Statistical Significance ◽

Binary Logistic Regression ◽

Cross Sectional Study ◽

Geographic Region ◽

Outcome Variable ◽

Cross Sectional ◽

Logistic Regression Models ◽

Long Term Impact ◽

The Impact

Study Design: The COrona VIrus Disease-19 (COVID-19) pandemic has disrupted craniomaxillofacial (CMF) surgeons practice worldwide. We implemented a cross-sectional study and enrolled a sample of CMF surgeons who completed a survey. Objective: To measure the impact that COVID-19 has had on CMF surgeons by (1) identifying variations that may exist by geographic region and specialty and (2) measuring access to adequate personal protective equipment (PPE) and identify factors associated with limited access to adequate PPE. Methods: Primary outcome variable was availability of adequate PPE for health-care workers (HCWs) in the front line and surgeons. Descriptive and analytic statistics were computed. Level of statistical significance was set at P < .05. Binary logistic regression models were created to identify variables associated with PPE status (adequate or inadequate). Results: Most of the respondents felt that hospitals did not provide adequate PPE to the HCWs (57.3%) with significant regional differences ( P = .04). Most adequate PPE was available to surgeons in North America with the least offered in Africa. Differences in PPE adequacy per region ( P < .001) and per country ( P < .001) were significant. In Africa and South America, regions reporting previous virus outbreaks, the differences in access to adequate PPE evaporated compared to Europe ( P = .18 and P = .15, respectively). Conclusion: The impact of COVID-19 among CMF surgeons is global and adversely affects both clinical practice and personal lives of CMF surgeons. Future surveys should capture what the mid- and long-term impact of the COVID-19 crisis will look like.

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Impact of malocclusion on the quality of life of children aged 8 to 10 years

Dental Press Journal of Orthodontics ◽

10.1590/2177-6709.23.2.046-053.oar ◽

2018 ◽

Vol 23 (2) ◽

pp. 46-53 ◽

Cited By ~ 9

Author(s):

Sônia Rodrigues Dutra ◽

Henrique Pretti ◽

Milene Torres Martins ◽

Cristiane Baccin Bendo ◽

Miriam Pimenta Vale

Keyword(s):

Quality Of Life ◽

Negative Impact ◽

Cross Sectional Study ◽

Cross Sectional ◽

Significance Level ◽

Normal Occlusion ◽

Study Results ◽

Belo Horizonte ◽

The Impact

ABSTRACT Objective: The aim of the present cross-sectional study was to assess the impact of malocclusion on the quality of life of children aged 8 to 10 years attending public elementary schools in Belo Horizonte, State of Minas Gerais, Brazil. Methods: The Brazilian version of the Child Perceptions Questionnaire 8-10 (CPQ8-10) was used to evaluate oral health-related quality of life. The children were examined for the diagnosis of malocclusion using the Dental Aesthetic Index (DAI). The data were analyzed by bivariate and multivariate descriptive statistics using Poisson regression at a 5% significance level. A total of 270 children participated in the study. Results: Children with normal occlusion or mild malocclusion (DAI ≤ 25) were 56% less likely (95%CI: 0.258-0.758; p= 0.003) to have their quality of life affected compared with children diagnosed with extremely severe malocclusion (DAI ≥ 36). Children with a maxillary anterior overjet ≥ 3 mm had higher CPQ8-10 mean scores (19.4; SD = 17.1) than those with an overjet < 3 mm (13.6; SD = 11.7; p= 0.038). Conclusions: Extremely severe malocclusion and pronounced maxillary anterior overjet were associated with a negative impact on quality of life.

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Prevalence of delirium, depression, anxiety, and post-traumatic stress disorder among COVID-19 patients: protocol for a living systematic review

Systematic Reviews ◽

10.1186/s13643-020-01507-2 ◽

2020 ◽

Vol 9 (1) ◽

Author(s):

Jiyuan Shi ◽

Ya Gao ◽

Liang Zhao ◽

Yuanyuan Li ◽

Meili Yan ◽

...

Keyword(s):

Systematic Review ◽

Post Traumatic Stress Disorder ◽

Traumatic Stress ◽

Stress Disorder ◽

Virus Disease ◽

Cochrane Library ◽

Post Traumatic Stress ◽

Cross Sectional ◽

Post Traumatic ◽

The Impact

Abstract Background Previous studies on the impact of corona virus disease 2019 (COVID-19) on the mental health of the patients has been limited by the lack of relevant data. With the rapid and sustained growth of the publications on COVID-19 research, we will perform a living systematic review (LSR) to provide comprehensive and continuously updated data to explore the prevalence of delirium, depression, anxiety, and post-traumatic stress disorder (PTSD) among COVID-19 patients. Methods We will perform a comprehensive search of the following databases: Cochrane Library, PubMed, Web of Science, EMBASE, and Chinese Biomedicine Literature to identify relevant studies. We will include peer-reviewed cross-sectional studies published in English and Chinese. Two reviewers will independently assess the methodological quality of included studies using the Joanna Briggs Institute Prevalence Critical Appraisal tool and perform data extraction. In the absence of clinical heterogeneity, the prevalence estimates with a 95% confidence interval (CI) of delirium, depression, anxiety, and post-traumatic stress disorder (PTSD) will be calculated by using random-effects model to minimize the effect of between-study heterogeneity separately. The literature searches will be updated every 3 months. We will perform meta-analysis if any new eligible studies or data are obtained. We will resubmit an updated review when there were relevant changes in the results, i.e., when outcomes became statistically significant (or not statistically significant anymore) or when heterogeneity became substantial (or not substantial anymore). Discussion This LSR will provide an in-depth and up-to-date summary of whether the common neuropsychiatric conditions observed in patients hospitalized for severe acute respiratory syndrome (SARS-CoV) and Middle East respiratory syndrome (MERS) are also prevalent in a different stage of COVID-19 patients. Systematic review registration PROSPERO CRD42020196610

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