scholarly journals RELATIONSHIP BETWEEN GRIP STRENGTH AND NONALCOHOLIC FATTY LIVER DISEASE IN MEN LIVING WITH HIV REFERRED TO A METABOLIC CLINIC

2018 ◽  
pp. 1-4
Author(s):  
P. Debroy ◽  
J.E. Lake ◽  
A. Malagoli ◽  
G. Guaraldi

This study aimed to assess the relationship between grip strength (GS) and nonalcoholic fatty liver (NAFLD) in treated HIV-infected men. We included 169 HIV-infected men. GS was assessed using a hand-grip dynamometer. NALFD was defined by liver-spleen attenuation ratio <1.1 on computed tomography. Mean (SD) age was 57 (6) years and BMI 24.5 (2.9) kg/m2. NAFLD was diagnosed in 33% of men; sarcopenia was present in 28%. Mean (SD) hand grip strength in the dominant hand was 37.5 (7.6) kg. In multivariate logistic regression, intermediate and low GS were associated with higher risk of NAFLD (OR 3.05; CI 1.27-7.61, p=0.01; OR 2.47; CI 1.01-6.19, p=0.05, respectively). GS has an inverse association with NAFLD prevalence in HIV-infected men. Specific mechanisms through which muscle weakness and NAFLD are related require further exploration but are not accounted for merely by the burden of comorbid illness, HIV disease stage, or ART exposure.

2018 ◽  
Vol 6 (4) ◽  
pp. 84
Author(s):  
Hakan Acar ◽  
Nebahat Eler

The index finger and the 4th finger ratio (2D:4D) is the indicator of the prenatal testosterone. The aim of this study is to investigate the relationship between 2D:4D, hand preference and hand grip strength in swimmers. A total of 80 elite swimmers, participated in the study. Height, body weight, body mass index (BMI), hand 2D:4D finger measurements and hand grip strength tests were performed for athletes. The hand preference was determined by the Oldfield questionnaire and it was evaluated according to the Geschwind score. The data were recorded in the SPSS 20 program and p<0.05 was considered as statistically significant. It was found that in both men and women, a negative correlation was found between right and left hand 2D:4D and both dominant (DHGS) and non-dominant hand grip strength (NDHGS) values. It was found that men had lower 2D:4D ratio than women. For both right and left handed, there was a statistically significant difference between the right and left hand 2D:4D ratios in both men and women (p<0.05) and the dominant hand (DH) 2D:4D ratios were found to be lower than non-dominant hand (NDH) 2D:4D ratios in both men and women (p<0.05)  It can be said that the 2D:4D ratios may be the effect of determining the hand preference, the grip strength and therefore the strength.


Author(s):  
Rachael N. Kinuthia ◽  
Joseph M. Thigiti ◽  
Benson N. Gakinya

Background: Human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) is associated with cognitive impairment which affects psychomotor speed. Psychomotor slowing is a predictor of dementia and death in people living with HIV and AIDS. The purpose of this study was to assess the relationship between HIV disease stage and psychomotor speed neurocognitive score which will add to the body of knowledge required to manage patients with HIV and AIDS. Objective: To determine the relationship between psychomotor speed neurocognitive score and the HIV disease stage in adults at initiation of care. Setting: This study was conducted at Kangundo Sub-county hospital comprehensive care centre. Methods: This was a cross-sectional study. All HIV seropositive patients aged 18 to 50 years recently initiated into care were studied. A pretested questionnaire was used to collect data. The World Health Organization (WHO) stage was used during data collection to classify study participants into asymptomatic and symptomatic groups. The grooved pegboard test was used to obtain psychomotor speed neurocognitive scores. Descriptive statistics were used to summarise data. Mann–Whitney U test, Spearman’s rho and multiple linear regression were employed in the analysis; p-value of 0.05 was considered significant. Results: The WHO stage did not have a significant effect on the psychomotor speed neurocognitive score (p ≥ 0.05). The CD4 count had a significant effect on psychomotor speed neurocognitive score (p = 0.001). Conclusions: There was a significant correlation between CD4 counts and psychomotor speed neurocognitive score. Efforts should be made to ensure that the CD4 counts of people living with HIV and AIDS do not continue to fall after initiation into care in order to preserve psychomotor function.


2018 ◽  
Vol 63 (1) ◽  
pp. 23-32 ◽  
Author(s):  
Carmen Ferragut ◽  
Helena Vila ◽  
Jose Arturo Abraldes ◽  
Carmen Manchado

Abstract The relationship between anthropometric and physical characteristics of female handball players and throwing velocity is considered an important factor in handball performance. The aim of this study was to examine key differences in anthropometric and fitness characteristics between top elite and elite female players competing in the first Spanish handball league. A total of 89 players from the first Spanish handball league were divided into two groups, top elite (38) and elite (51) players, and assessed for anthropometric and fitness characteristics (throwing velocity, vertical jump and hand grip strength). A Student’s t-test was used to determine whether a statistically significant difference between the two different levels of play occurred. Significant differences were found in age, body height, body mass, arm span, muscle mass, different girths (tensed and flexed arm, forearm, wrist, ankle), dominant hand width and length, different breadths (biacromial, bitrochanteric, bistyloid breadth and biepicondylar humerus) and fitness characteristics (hand grip strength and throwing velocity for different positions). Top elite players compared to elite players showed differences in anthropometric characteristics which were mainly located in the upper limbs and mostly were nonmodifiable aspects by training. Furthermore, the best players were able to maintain a high throwing velocity in different tactical situations.


2018 ◽  
Vol 6 (5) ◽  
pp. 170 ◽  
Author(s):  
Nebahat Eler ◽  
Serdar Eler

Lateralization, which is also known as hand preference, and 2D:4D finger ratio is a sign of prenatal testosterone and known to be associated with strength. The aim of this study is to investigate the relationship between 2D: 4D, lateralization and hand grip strength in relation to hand and forearm that are thought to be effective in handball in elite handball players. 67 female and 67 male elite players participated in this study. The height, weight, body-mass index and hand preference of these athletes have been identified and 2D: 4D finger measurements and hand grip strength tests were performed. When identifying the preferences regarding lateralization, the hand distribution preference was determined by the Oldfield questionnaire and evaluated using the Geschwind score. After photocopy images of the two hands of the athletes were taken, their finger lengths were measured Hand grip strength was determined by a Jamar hydraulic dynamometer. Strong correlation was found especially between 2D: 4D and dominant hand grip strength in male and female elite handball players. The ratio of left-handedness due to the positions of players during the game among male and female athletes has been found to be higher than that of the general population. With regard to gender, 2D: 4D was found to be lower in males than females but hand grip was found to be higher in males than females. Besides, a significant correlation between height and BMI with 2D:4D, sport age, height, body weight and hand grip strength was found. This study emphasizes the importance of 2D: 4D, handgrip strength and hand preference in handball.


2019 ◽  
Author(s):  
Jenevieve Opoku ◽  
Rupali K Doshi ◽  
Amanda D Castel ◽  
Ian Sorensen ◽  
Michael Horberg ◽  
...  

BACKGROUND HIV cohort studies have been used to assess health outcomes and inform the care and treatment of people living with HIV disease. However, there may be similarities and differences between cohort participants and the general population from which they are drawn. OBJECTIVE The objective of this analysis was to compare people living with HIV who have and have not been enrolled in the DC Cohort study and assess whether participants are a representative citywide sample of people living with HIV in the District of Columbia (DC). METHODS Data from the DC Health (DCDOH) HIV surveillance system and the DC Cohort study were matched to identify people living with HIV who were DC residents and had consented for the study by the end of 2016. Analysis was performed to identify differences between DC Cohort and noncohort participants by demographics and comorbid conditions. HIV disease stage, receipt of care, and viral suppression were evaluated. Adjusted logistic regression assessed correlates of health outcomes between the two groups. RESULTS There were 12,964 known people living with HIV in DC at the end of 2016, of which 40.1% were DC Cohort participants. Compared with nonparticipants, participants were less likely to be male (68.0% vs 74.9%, <i>P</i>&lt;.001) but more likely to be black (82.3% vs 69.5%, <i>P</i>&lt;.001) and have a heterosexual contact HIV transmission risk (30.3% vs 25.9%, <i>P</i>&lt;.001). DC Cohort participants were also more likely to have ever been diagnosed with stage 3 HIV disease (59.6% vs 47.0%, <i>P</i>&lt;.001), have a CD4 &lt;200 cells/µL in 2017 (6.2% vs 4.6%, <i>P</i>&lt;.001), be retained in any HIV care in 2017 (72.9% vs 59.4%, <i>P</i>&lt;.001), and be virally suppressed in 2017. After adjusting for demographics, DC Cohort participants were significantly more likely to have received care in 2017 (adjusted odds ratio 1.8, 95% CI 1.70-2.00) and to have ever been virally suppressed (adjusted odds ratio 1.3, 95% CI 1.20-1.40). CONCLUSIONS These data have important implications when assessing the representativeness of patients enrolled in clinic-based cohorts compared with the DC-area general HIV population. As participants continue to enroll in the DC Cohort study, ongoing assessment of representativeness will be required.


Medicine ◽  
2017 ◽  
Vol 96 (39) ◽  
pp. e8164 ◽  
Author(s):  
Xiao-Long Yu ◽  
Long Shu ◽  
Xiao-Ming Shen ◽  
Xiao-Yan Zhang ◽  
Pei-Fen Zheng

2016 ◽  
Vol 19 (3) ◽  
pp. 23 ◽  
Author(s):  
Tilak Francis ◽  
Siva Anandhi

<p><strong>Objective: </strong>The  key  factor  for  potency  of  the  teeth  is  their  muscular  strength.  The dominant  hand  plays  an  important  role  in  most  of  the  daily  muscular  activities  involving  dental  procedure.  There  are  many  factors,  which  may  affect  the  grip strength,  and  very  few  studies  especially  in  India  have  shown  their  correlation with  grip  strength. Work related musculoskeletal disorders (WRMSD) are an important occupational health problem affecting dental practitioners. This study assessed the prevalence of WRMSD in dental interns in relation to the thumb length and hand grip strength. <strong>Material and Methods</strong>: Thumb  length  template,  jammer  dynamometer,  nine-hole  peg board,  and RULA   assessment. Methods: Thumb  length  was measured  by  thumb  length template.  Grip  strength was measured  by  jammer  dynamometer, unilateral  hand  finger  dexterity was measured  by  nine-hole  pegboard,  and  work  related  musculoskeletal  disorder  was assessed  by  RULA. <strong>Results</strong>: Thumb  length was  positively   correlated  with  grip  strength  and  work related  musculoskeletal  disorder.  Thumb  length  was  negatively  correlated  with unilateral  hand  finger  dexterity  among  dental  professionals. <strong>Conclusion</strong>: Thumb  length  is  a  better  predictor  for  measuring  hand  grip strength   and   work related musculoskeletal   disorder,   than    unilateral   hand   finger dexterity.</p><p><strong>Keywords</strong></p><p>Dental professional; Hand grip strength; Thumb length; Unilateral hand finger dexterity; Work related musculoskeletal disorder.                                            </p>


2021 ◽  
Vol 16 (1) ◽  
pp. 59-73
Author(s):  
Amreen Dinani ◽  
Ali Khan ◽  
Douglas Dieterich

Fatty liver disease is a growing concern in people living with HIV, the main drivers are alcoholic liver disease and nonalcoholic fatty liver disease. It has shown to negatively impact HIV care continuum and result in notable non-HIV related morbidity and mortality. With the advancement in antiretroviral therapy and effective direct acting antivirals, fatty liver disease is surfacing as the next big challenge in this population like that observed in the general population. This review article summarizes the gravity of these two common diseases in HIV-infected people and aims to sheds light on an unmet need to develop effective methods to identify, screen and manage fatty liver disease in this unique population.


2019 ◽  
Vol 12 ◽  
pp. 117863881984748 ◽  
Author(s):  
Pratima Dibba ◽  
Andrew A Li ◽  
George Cholankeril ◽  
Muhammad Ali Khan ◽  
Donghee Kim ◽  
...  

Nonalcoholic fatty liver disease (NAFLD) develops when the liver is unable to oxidize or export excess free fatty acids generated by adipose tissue lipolysis, de novo lipogenesis, or dietary intake. Although treatment has generally been centered on reversing metabolic risk factors that increase the likelihood of NAFLD by influencing lifestyle modifications, therapeutic modalities are being studied at the cellular and molecular level. The endocannabinoid system has been of recent focus. The agonism and antagonism of cannabinoid receptors play roles in biochemical mechanisms involved in the development or regression of NAFLD. Exocannabinoids and endocannabinoids, the ligands which bind cannabinoid receptors, have been studied in this regard. Exocannabinoids found in cannabis (marijuana) may have a therapeutic benefit. Our recent study demonstrated an inverse association between marijuana use and NAFLD among adults in the United States. This commentary combines knowledge on the role of the endocannabinoid system in the setting of NAFLD with the findings in our article to hypothesize different potential mechanisms that may influence the inverse relationship between cannabis and NAFLD.


2018 ◽  
Vol 26 (3) ◽  
pp. 457-461 ◽  
Author(s):  
Hitoshi Koda ◽  
Yoshihiro Kai ◽  
Shin Murata ◽  
Hironori Osugi ◽  
Kunihiko Anami ◽  
...  

The purpose of this study was to investigate the relationship between muscle strength asymmetry and body sway while walking. We studied 63 older adult women. Strong side and weak side of knee extension strength, toe grip strength, hand grip strength, and body sway while walking were measured. The relationship between muscle strength asymmetry for each muscle and body sway while walking was evaluated using Pearson’s correlation coefficient. Regarding the muscles recognized to have significant correlation with body sway, the asymmetry cutoff value causing an increased sway was calculated. Toe grip strength asymmetry was significantly correlated with body sway. Toe grip strength asymmetry causing an increased body sway had a cutoff value of 23.5%. Our findings suggest toe grip strength asymmetry may be a target for improving gait stability.


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