scholarly journals Mucormycosis: A challenge with COVID-19

2021 ◽  
Author(s):  
Mohammod Kamrul Islam
Keyword(s):  
Early Diagnosis ◽  
Fungal Infection ◽  
Paranasal Sinuses ◽  
The Body ◽  
Affected Patient ◽  
Life Threatening ◽  
Disseminated Mucormycosis ◽  
Mucor Species

Mucormycosis is an aggressive opportunistic fungal infection caused by fungi of the Phycomycetes class including Rhizopus species and Mucor species. The pathogen can be present in the environment, on the skin, and in the orifices of the body. There are several types including Rhinocerebral, Pulmonary, Gastrointestinal, Cutaneous, and Disseminated Mucormycosis.1 The spores infect the paranasal sinuses and nasopharynx, extending to the orbit and brain cavity in persons who have reduced cellular and humoral defenses. During the ongoing COVID-19 pandemic, a surge in the cases of rhino-orbital mucormycosis has become a life-threatening combination. Early diagnosis and intervention in the only way to save the vision and life of the affected patient.

MR IMAGING OF RHINO-ORBITAL-CEREBRAL MUCORMYCOSIS IN POST COVID PATIENT: CASE SERIES

2021 ◽  
pp. 38-40
Author(s):  
Anupriya Mishra ◽  
Ravi Shankar Choubey
Keyword(s):  
Early Diagnosis ◽  
Mr Imaging ◽  
Fungal Infection ◽  
Nasal Cavity ◽  
Paranasal Sinuses ◽  
Rhizopus Oryzae ◽  
Case Series ◽  
Patient Case ◽  
Orbital Cavity ◽  
Life Threatening

Rhino-orbital-cerebral Mucormycosis also known as orbital zygomycosis. It is a life-threatening deadly complication in post covid patient presenting as pathological involvement of nasal cavity and paranasal sinuses with extension into orbital cavity and intracranial compartment as a result of fungal infection caused by fungi in the order Mucorales, mainly Rhizopus oryzae. MATERIAL AND METHOD We present a case series of 5 patient who were biopsy/culture proven invasive rhino cerebral Mucormycosis in post covid-19 patient who were reviewed on MR imaging. MR imaging were recovered from PACS in PMCH Patna and the data was analyzed. RESULT Involvement of para nasal sinuses with adjacent fat standing was present in 100%, orbital involvement was seen in 80%, intracerebral involvement was seen in 60%, mastoiditis was present in 40% of the patient selected in our case series. CONCLUSION MR imaging is helpful in early diagnosis when there is involvement of nasal, paranasal sinus and varying degree of orbital and cranial extension and associated with varying complication

From strongyloidiasis to disseminated mucormycosis: the story of an HTLV-1-infected migrant

2020 ◽  
Author(s):  
Brice Autier ◽  
Adélaïde Chesnay ◽  
Claire Mayence ◽  
Stéphanie Houcke ◽  
Hélène Guégan ◽  
...  
Keyword(s):  
Immune Deficiency ◽  
Strongyloides Stercoralis ◽  
The Body ◽  
Life Threatening ◽  
Disseminated Strongyloidiasis ◽  
Disseminated Mucormycosis

Strongyloidiasis manifestations range from asymptomatic cases to the life-threatening disseminated strongyloidiasis in case of immune deficiency: larvae migrate throughout the body, disseminating germs from the digestive flora to various organs. Here, we described a case of disseminated mucormycosis consecutive to Strongyloides stercoralis hyperinfestation in a Surinamese migrant infected with HTLV-1.

scholarly journals Mucormycosis (Black fungus): An alarming sign for COVID-19 patients

2021 ◽  
Vol 6 (3) ◽  
pp. 136-139
Author(s):  
Ritesh Kumar Srivastav ◽  
Vishal Kumar Vishwakarma ◽  
Shiv Kumar Srivastav ◽  
Mahesh Prasad ◽  
Tarique Mahmood ◽  
...  
Keyword(s):  
Fungal Infection ◽  
Fungal Spores ◽  
Body Part ◽  
The Body ◽  
Fatality Rate ◽  
Health Issues ◽  
Pulmonary Infections ◽  
Skin Injury ◽  
Underlying Condition ◽  
Disseminated Mucormycosis

Mucormycosis (also known as zygomycosis) is a dangerous but uncommon fungal infection caused by a fungus known as mucormycetes. Mucormycosis can be caused by a variety of fungi. Mucormycetes are fungi that belong to the Mucorales scientific order. Molds can be found all over the place. Mucormycosis is a fungal infection that primarily affects persons who have health issues or who use medications that reduce the body's capacity to resist infections and illness. After inhaling fungal spores from the air, it most usually affects the sinuses or lungs. The majority of people are unaffected by these fungus. Breathing in mucormycete spores, on the other hand, can induce an infection in the lungs or sinuses, which can spread to other regions of the body in patients with compromised immune systems. It can also happen as a result of a cut, a burn, or another sort of skin injury. The fatality rate varied based on the patient's underlying condition, the type of fungus, and the affected body part (for example, the mortality rate was 46 percent among people with sinus infections, 76 percent for pulmonary infections, and 96 percent for disseminated mucormycosis). Antifungal medicines such as amphotericin-B, isavuconazole, posaconazole, and various combinations are used to inhibit the growth. Mucormycosis was studied for its spread, symptoms, treatment, prevention, and consequences.

Review on Mucormycosis: It is a life Threatening infection

2021 ◽  
pp. 316-318
Author(s):  
S.D. Mankar ◽  
Waditake Poonam ◽  
Prajakta Jejurkar
Keyword(s):  
Fungal Infection ◽  
Organic Waste ◽  
The Body ◽  
Health Issues ◽  
Home Remedies ◽  
Animal Dung ◽  
The World ◽  
Life Threatening ◽  
Ayurvedic Treatment

Mucormycosis, often known as black fungus, is a fungal infection caused by the mucormycetes fungi. Zygomycetes is a class of fungi. Mucormycetes, the fungus that cause mucormycosis, are found all throughout the world, especially in soil and in decaying organic waste like leaves, compost piles, and animal dung. It is not contagious and cannot be passed from one person to another. Mucormycosis (also known as zygomycosis) is a dangerous but uncommon fungal infection caused by a fungus known as mucormycetes. Molds can be found all over the place. Mucormycosis is a fungal infection that primarily affects persons who have health issues or who use medications that reduce the body's capacity to resist infections and illness. Infections are most typically acquired when mould spores are inhaled or, less commonly, when spores enter the body through a cut in the skin. It takes place after COVID-19. Home remedies, such as consuming probiotics, and foods that promote immunity, can help to minimise mucormycosis. The main purpose of this review Related to Mucormycosis is to diminish the growth of Mucormycosis by taking Ayurvedic Treatment.

scholarly journals COVID-19 Associated Rhino-Orbital Mucormycosis Complicated by Gangrenous and Bone Necrosis—A Case Report from Honduras

Vaccines ◽  
2021 ◽  
Vol 9 (8) ◽  
pp. 826
Author(s):  
Elsa Yolanda Palou ◽  
María Auxiliadora Ramos ◽  
Emec Cherenfant ◽  
Adoni Duarte ◽  
Itzel Carolina Fuentes-Barahona ◽  
...  
Keyword(s):  
Risk Factors ◽  
Case Report ◽  
Early Diagnosis ◽  
Fungal Infection ◽  
Invasive Fungal Infection ◽  
Immunocompromised Patients ◽  
Bone Necrosis ◽  
Inappropriate Use ◽  
Prompt Treatment ◽  
Life Threatening

Background: Mucormycosis is a life-threatening invasive fungal infection most commonly observed in immunocompromised patients. Throughout the COVID-19 pandemic, a growing number of Mucorales associated infections, now termed COVID-19 associated mucormycosis (CAM), have been reported. Despite an increase in fatality reports, no cases of rhino-orbital CAM complicated with gangrenous bone necrosis have been described in the literature to date. Case: A 56-year-old male with a recent COVID-19 diagnosis developed rhino-orbital mucormycosis after 22 days of treatment with dexamethasone. Cultures and histopathological assessment of tissue biopsy confirmed the diagnosis. The patient survived after treatment with amphotericin B. Conclusions: Mucormycosis is an invasive fungal infection affecting mostly immunocompromised patients. Along with the COVID-19 pandemic, the inappropriate use of steroids, in addition to concurrent risk factors, such as diabetes, has led to an increase in the occurrence of these devastating mycoses, leading to the development of severe presentations and complications, as observed in many cases. Early diagnosis and prompt treatment are crucial in order to avoid dissemination and fatal outcomes.

scholarly journals Mucormycosis involving paranasal sinuses in a post-COVID-19 patient with an uncontrolled diabetes-A rare presentation in an ongoing pandemic

2021 ◽  
Vol 6 (2) ◽  
pp. 137-140
Author(s):  
Sankalp Yadav ◽  
Novelesh Bachchan ◽  
Gautam Rawal ◽  
Pallawi Rai
Keyword(s):  
Mortality Rate ◽  
Fungal Infection ◽  
Opportunistic Infection ◽  
Paranasal Sinuses ◽  
Ethmoid Sinus ◽  
Rare Presentation ◽  
Uncontrolled Diabetes ◽  
Life Threatening ◽  
Second Wave ◽  
Indian Male

Mucormycosis (MCR) involving paranasal sinuses is a rare life-threatening opportunistic infection in immunocompromised individuals. In humans, MCR is considered as one of the most rapidly progressive lethal forms of fungal infection with a high mortality rate of 70–100%. During the second wave of COVID-19 in India, the cases of MCR have increased rapidly. We herein report a case of a 70-year-old Indian male with an uncontrolled diabetes diagnosed as maxillary and ethmoid sinus MCR.

scholarly journals Aspergillosis in immunocompromised children acute myeloid leukemia and bone marrow aplasia.: Report of two cases

1994 ◽  
Vol 36 (5) ◽  
pp. 465-469
Author(s):  
Maria Zilda de Aquino ◽  
Alberto Brasaciner ◽  
Lilian Maria Cristófani ◽  
Paulo Taufic Maluf ◽  
Vicente Odone Filho ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Acute Myeloid Leukemia ◽  
Early Diagnosis ◽  
Fungal Infection ◽  
Invasive Aspergillosis ◽  
Paranasal Sinuses ◽  
Myeloid Leukemia ◽  
The Other ◽  
Bone Marrow Aplasia ◽  
Acute Myeloid

Two cases of Aspergillosis in immunocompromised children are reported. Both were caused by Aspergillns flavus. Early diagnosis and treatment led to the remission of the process. One patient had acute myeloid leukemia; the fungus was isolated from the blood. The other patient with bone marrow aplasia, presented an invasive aspergillosis of the paranasal sinuses with dissemination of fungal infection; the diagnosis was obtained by histology and culture of biopsied tissue from a palatal ulceration.

Image findings in patients with chronic invasive fungal infection of paranasal sinuses

2021 ◽  
Author(s):  
Se Jin Cho ◽  
Young Jun Choi ◽  
Kyung-Ja Cho ◽  
Ji Heui Kim ◽  
Sae Rom Chung ◽  
...  
Keyword(s):  
Fungal Infection ◽  
Invasive Fungal Infection ◽  
Paranasal Sinuses ◽  
Chronic Invasive

scholarly journals Microbiota of the Tongue and Systemic Connections: The Examination of the Tongue as an Integrated Approach in Oral Medicine

Hygiene ◽  
2021 ◽  
Vol 1 (2) ◽  
pp. 56-68
Author(s):  
Cinzia Casu ◽  
Giovanna Mosaico ◽  
Valentino Natoli ◽  
Antonio Scarano ◽  
Felice Lorusso ◽  
...  
Keyword(s):  
Early Diagnosis ◽  
Survival Rates ◽  
Integrated Approach ◽  
Potential Method ◽  
The Body ◽  
Oral Medicine ◽  
Next Generation Sequencing Technology ◽  
Advanced Phase ◽  
Holistic Concept ◽  
Unique Method

The tongue is able to quickly reflect the state of health or disease of the human body. Tongue inspection is an important diagnostic approach. It is a unique method that allows to explore the pathogenesis of diseases based on the guiding principles of the holistic concept that involves the observation of changes in the lining of the tongue in order to understand the physiological functions and pathological changes of the body. It is a potential method of screening and early detection of cancer. However, the subjective inspection of the tongue has a low reliability index, and therefore computerized systems of acquisition of diagnostic bioinformation have been developed to analyze the lining of the tongue. Next-generation sequencing technology is used to determine the V2–V4 hypervariable regions of 16S rRNA to study the microbiota. A lot of neoplasms are identified only at an advanced phase, while in the early stages, many subjects remain in an asymptomatic form. On the contrary, the early diagnosis is able to increase the prognosis of cancer and improve the survival rates of subjects. Evidently, it is necessary to develop new strategies in oral medicine for the early diagnosis of diseases, and the diagnosis of the tongue as a minimally invasive method is certainly one of them.

Wegener’s granulomatosis: diagnostic dilemma

2001 ◽  
Vol 115 (1) ◽  
pp. 46-47 ◽  
Author(s):  
A. Banerjee ◽  
J. M. Armas ◽  
J. H. Dempster
Keyword(s):  
Early Diagnosis ◽  
Wegener’S Granulomatosis ◽  
Systemic Disease ◽  
Wegener's Granulomatosis ◽  
The Body ◽  
Facial Nerve Paralysis ◽  
Diagnostic Dilemma ◽  
Nerve Paralysis ◽  
Atypical Presentations ◽  
High Index Of Suspicion

Wegener’s granulomatosis is a systemic disease characterized by a granulomatous lesion that can affect any organ throughout the body.This case-report illustrates the problem posed by a patient presenting with bilateral serous otitis media with marked sensorineural hearing loss, facial nerve paralysis and an atypical serological picture. The importance of early diagnosis and the protocol for the management of a patient with an uncertain diagnosis is discussed. Due to atypical presentations, only a high index of suspicion will ensure an early diagnosis.

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