scholarly journals EFFECT OF GLUCOCORTICOID THERAPY FOR CONGENITAL ADRENAL HYPERPLASIA IN ADULT PATIENTS ON REDUCTION OF BONE MINERAL DENSITY

2014 ◽  
Vol 17 (2) ◽  
pp. 26-28
Author(s):  
A I Sazonova ◽  
N V Molashenko ◽  
E A Troshina
Keyword(s):  
Bone Mineral Density ◽  
Congenital Adrenal Hyperplasia ◽  
Bone Mineral ◽  
Serum Vitamin ◽  
Adult Patients ◽  
Adrenal Hyperplasia ◽  
Mineral Density ◽  
Serum Vitamin D ◽  
Early Correction ◽  
Markers Of Bone Turnover

Congenital adrenal hyperplasia (CAH) is a disease leading to decreased adrenal cortisol secretion which requires lifelong treatment with glucocorticoids (GC). However the question whether these patients need regular DXA screening for osteoporosis is still widely discussed in literature. The aim of this study was to evaluate bone mineral density (BMD) in adult patients with classical forms of CAH in Russian population. We have shown that 22% of patients had low BMD which had no correlation with compensation and GC doses. There were no significant deviations in biochemical markers of bone turnover levels. The serum Vitamin D deficiency was found in 89% of patients with CAH which needed early correction in patients with low BMD.

Bone mineral density and serum vitamin D status in Parkinson's disease: Are the stage and clinical features of the disease important?

2020 ◽  
Vol 68 (2) ◽  
pp. 394 ◽  
Author(s):  
ErhanArif Ozturk ◽  
Ibrahim Gundogdu ◽  
Burak Tonuk ◽  
Ebru Umay ◽  
BilgeGonenli Kocer ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Parkinson’S Disease ◽  
Vitamin D ◽  
Parkinson's Disease ◽  
Clinical Features ◽  
Bone Mineral ◽  
Serum Vitamin ◽  
Vitamin D Status ◽  
Mineral Density ◽  
Serum Vitamin D

Bone mineral density and its influencing factors in children with idiopathic nephrotic syndrome: a prospective observational study

2019 ◽  
Vol 49 (4) ◽  
pp. 292-298
Author(s):  
Indar K Sharawat ◽  
Lesa Dawman ◽  
Merabhai V Kumkhaniya ◽  
Kusum Devpura ◽  
Amarjeet Mehta
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Nephrotic Syndrome ◽  
Bone Mineral ◽  
Idiopathic Nephrotic Syndrome ◽  
Serum Vitamin ◽  
Z Score ◽  
Mineral Density ◽  
Serum Vitamin D ◽  
Vitamin D Levels

Glucocorticoids are first-line therapy for children with idiopathic nephrotic syndrome (INS). These children are at risk of deranged bone metabolism and low bone mineral density (BMD). We studied 60 children with INS and divided them into two groups. Group 1 included 21 children (initial and infrequent relapsing) and group 2 included 39 children (frequent relapsing, steroid dependent and steroid resistant). Dual-energy X-ray absorptiometry of the lumbar spine was performed to assess BMD. Mean BMD Z-score was compared in both groups; this correlated significantly on univariate analysis with cumulative steroid dose, serum vitamin D levels and calcium supplementation. However, on multivariate analysis, serum vitamin D level was the only factor significantly predictive of low z-score.

scholarly journals Cardiorespiratory Fitness is Inversely Associated with Risk of Low Bone Mineral Density in Older Korean Men

2020 ◽  
Vol 17 (21) ◽  
pp. 7907
Author(s):  
Inhwan Lee ◽  
Jeonghyeon Kim ◽  
Hyunsik Kang
Keyword(s):  
Physical Activity ◽  
Bone Mineral Density ◽  
Cardiorespiratory Fitness ◽  
Bone Mineral ◽  
Serum Vitamin ◽  
Cross Sectional Study ◽  
Mineral Density ◽  
Cross Sectional ◽  
Serum Vitamin D ◽  
Age Related

Little is known regarding the association between physical fitness and bone health in older Korean men. This study investigated the relationship between estimated cardiorespiratory fitness (eCRF) and bone mineral density (BMD). This cross-sectional study included 2715 Korean men aged 50 years and older selected from those who participated in the 2008–2011 Korea National Health and Nutritional Examination and Survey. eCRF was obtained using a sex-specific algorithm developed on the basis of age, body mass index, resting heart rate, and physical activity and classified into low, middle, and high categories. Femoral neck BMD was assessed by dual X-ray absorptiometry. Odds ratios (OR) and 95% confidence intervals (CI) for osteopenia, osteoporosis, and low BMD were calculated for eCRF categories in models fully adjusted for age, waist circumference, education, income, smoking, heavy alcohol intake, serum vitamin D, serum parathyroid hormone, and dietary intake of energy, protein, calcium, and vitamins A and C. Overall, eCRF levels were positively associated with BMD and negatively with prevalence of osteopenia, osteoporosis, and low BMD. Logistic regression showed inverse trends in the risks of osteopenia (high vs. low: OR = 0.692; 95% CI, 0.328–0.517; p = 0.049) and low BMD (high vs. low: OR = 0.669; 95% CI, 0.497–0.966; p = 0.029) by eCRF category in models fully adjusted for all the measured covariates. The current findings suggest that maintaining high eCRF via regular physical activity may contribute to attenuation of age-related loss of BMD and decreased risk for low BMD in older Korean men.

Classical congenital adrenal hyperplasia due to 21-hydroxylase deficiency: a cross-sectional study of factors involved in bone mineral density

2003 ◽  
Vol 21 (6) ◽  
pp. 396-401 ◽  
Author(s):  
Patr�cia Oliveira de Almeida Freire ◽  
Sofia Helena Valente de Lemos-Marini ◽  
Andr�a Trevas Maciel-Guerra ◽  
Andr� Moreno Morcillo ◽  
Maria Tereza Matias Baptista ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Congenital Adrenal Hyperplasia ◽  
Bone Mineral ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Adrenal Hyperplasia ◽  
Mineral Density ◽  
Hydroxylase Deficiency ◽  
Cross Sectional ◽  
21 Hydroxylase Deficiency
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