scholarly journals Fatigue and Functional Independence inPeople with Multiple Sclerosis

2021 ◽  
Vol 37 (1) ◽  
pp. 67-83
Author(s):  
Juliana Jaramillo Buitrago ◽  
Julio Ernesto Pérez Parra
Keyword(s):  
Diabetes Mellitus ◽  
Multiple Sclerosis ◽  
Functional Independence ◽  
Esclerosis Múltiple ◽  
Multiple Material

Objetivo: Establecer la relación entre la fatiga y el nivel de independencia funcional en actividades de la vida diaria en personas con esclerosis múltiple. Material y método: Se realizó un estudio descriptivo trasversal con alcance correlacional. Participaron 107 personas con esclerosis múltiple, mayores de 18 años con puntuaciones entre 0 y 8 en la Escala Ampliada del Estado de Discapacidad de Kurtzke. Se evaluó la fatiga con la Escala de Gravedad de la Fatiga, las actividades básicas cotidianas con el Índice de Barthel y las instrumentales con la Escala de Lawton y Brody. Se correlacionaron estas variables y se realizaron pruebas de homogeneidad entre la severidad de la fatiga y variables sociodemográficas y clínicas. Resultados: Se encontró una relación significativa inversamente proporcional entre el grado de severidad de la fatiga y las variables de dependencia para las actividades básicas e instrumentales de la vida diaria (p<0,001). No se evidenció relación significativa entre la severidad de la fatiga con la edad, el sexo y el tiempo de evolución de la esclerosis múltiple (p>0,05). Se encontraron diferencias significativas en el nivel de fatiga respecto al uso de ayudas externas, hipertensión arterial, diabetes mellitus, compromiso motor, trastornos de la sensibilidad, alteraciones del control de esfínteres, deterioro cognitivo y depresión. Conclusiones: Se encontró que la fatiga fue el síntoma más predominante (>75%). Las personas que informan altos niveles de fatiga mostraron menor independencia para las actividades de la vida diaria.

Clinical and molecular findings in multiple sclerosis patients with type 1 diabetes mellitus

1999 ◽  
Vol 6 (5) ◽  
pp. 373-374 ◽  
Author(s):  
Klaus-Peter Wandinger ◽  
Peter Trillenberg ◽  
Harald Klüter ◽  
Karl Wessel ◽  
Holger Kirchner
Keyword(s):  
Diabetes Mellitus ◽  
Multiple Sclerosis ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Multiple Sclerosis Patients

scholarly journals El efecto de la terapia acuática en el plasma y la interleucina-12 y 17 en pacientes con esclerosis múltiple

2019 ◽  
Vol 8 (1) ◽  
pp. 89-94
Author(s):  
S. Nejatpour ◽  
M. Fathei ◽  
A. Yaghoubi
Keyword(s):  
Multiple Sclerosis ◽  
Exercise Group ◽  
Interleukin 12 ◽  
Interleukin 17 ◽  
Esclerosis Múltiple ◽  
Intervention Protocol ◽  
Before And After ◽  
Post Test ◽  
Factores De Riesgo ◽  
And Control

Las citocinas como la interleucina-12 (IL-12) y la interleucina-17 (IL-17) influyen en la función del sistema inmune y los diferentes tejidos, siendo estudiadas debido al papel que desempeñan en la Esclerosis Múltiple (EM). El objetivo de este estudio fue investigar el efecto de la terapia acuática en la IL-12 y la IL-17 en pacientes con esclerosis múltiple. Participaron 25 hombres con esclerosis múltiple, los cuales fueron divididos en dos grupos: ejercicio y control. Se tomó una muestra de sangre antes y después de la intervención. El grupo de ejercicio llevó a cabo tres sesiones por semana durante ocho semanas. Las partes inicial y final de cada sesión incluyeron calentamiento y vuelta a la calma, llevadas a cabo en zonas poco profundas. Las actividades fueron diseñadas y llevadas a cabo por un investigador bajo la supervisión de un fisiólogo deportivo y un neurólogo experimentado. Durante las sesiones de entrenamiento, se dedicaban los primeros 10 minutos al calentamiento y los últimos 5 minutos a la vuelta a la calma. La intensidad del ejercicio fue aproximadamente del 75% de la frecuencia cardíaca máxima. Los datos demostraron que tanto IL-12 como IL-17 disminuyeron significativamente entre el pre-test y el post-test. Por tanto, se concluye que la terapia acuática puede reducir los factores de riesgo con respecto a la esclerosis múltiple, incluidas la IL-12 y la IL-17. Cytokines such as Interleukin 12 (IL-12) and Interleukin 17(IL-17) influence the function of the immune system and different tissues and are studied due to the role they play in Multiple Sclerosis (MS). The aim of the study was to investigate the effect of aqua-therapy on plasma IL-12 and IL-17 in patients with MS. 25 men with MS were divided into two groups: exercise and control. Blood sample was taken before and after the intervention protocol. The exercise group carried out three exercise sessions per week during eight weeks. The beginning and final parts of each session included warming up and cool down, and were carried out in shallow areas. These activities were designed and implemented by a researcher under the supervision of a sports physiologist and an experienced neurologist. During the training sessions, the first 10 minutes were for warming up, and the last 5 minutes of training were for cool down. Exercise intensity was approximately 75% of heart rate reserve. The data demonstrated that both IL-12 and IL-17 decreased significantly from pre-test to post-test in the exercise group. We conclude that aqua-training may reduce risk factors regarding multiple sclerosis, including IL-12 and IL-17.

scholarly journals Multiple Sclerosis and Diabetes Mellitus: Further Evidence of a Relationship

1982 ◽  
Vol 9 (4) ◽  
pp. 415-419 ◽  
Author(s):  
Sharon A. Warren ◽  
K.G. Warren
Keyword(s):  
Diabetes Mellitus ◽  
Multiple Sclerosis ◽  
Healthy Controls ◽  
Degree Relative ◽  
Significant Difference ◽  
The Difference ◽  
The Relationship ◽  
Prevalence Of Diabetes Mellitus ◽  
Second Degree

SUMMARY:One hundred multiple sclerosis (MS) patients were compared to healthy controls to determine the prevalence of diabetes mellitus in their families. Significantly, more MS patients than controls were diabetic or reported at least one first degree relative (parent, sibling, child) with diabetes. The relationship between MS and diabetes persisted when second degree relatives (grandparents, aunts and uncles) were taken into consideration.A greater percentage of MS patients with another MS relative were diabetic or reported a first degree relative with diabetes mellitus than MS patients without an MS relative. However the difference was not statistically significant. Nor was there a significant difference when percentages reporting either a first or a second degree relative with diabetes were compared.

scholarly journals Helicobacter pylori in the clinic of internal medicine

2021 ◽  
Vol 2021 (1) ◽  
pp. 17-21
Author(s):  
T.D. Zvyagintseva ◽  
◽  
Ya.K. Gamanenko ◽  
Keyword(s):  
Internal Medicine ◽  
Diabetes Mellitus ◽  
Multiple Sclerosis ◽  
Metabolic Syndrome ◽  
Helicobacter Pylori ◽  
Cardiovascular Diseases ◽  
Helicobacter Pylori Infection ◽  
Relationship Of

The article is devoted to the analysis of the literature on the problem of the possible relationship of Helicobacter pylori in the pathogenesis of various extragastric pathologies - diabetes mellitus, metabolic syndrome, cardiovascular diseases and multiple sclerosis. It is possible that Helicobacter pylori infection plays an independent role in the pathogenesis of these diseases.

scholarly journals Symptomatic Therapy and Rehabilitation in Primary Progressive Multiple Sclerosis

2011 ◽  
Vol 2011 ◽  
pp. 1-22 ◽  
Author(s):  
Fary Khan ◽  
Bhasker Amatya ◽  
Lynne Turner-Stokes
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Demyelinating Disease ◽  
Disease Onset ◽  
Functional Independence ◽  
Symptomatic Therapy ◽  
Primary Progressive Multiple Sclerosis ◽  
Primary Progressive ◽  
Relapsing Remitting

Multiple sclerosis (MS) is an autoimmune inflammatory demyelinating disease of the central nervous system and a major cause of chronic neurological disability in young adults. Primary progressive MS (PPMS) constitutes about 10% of cases, and is characterized by a steady decline in function with no acute attacks. The rate of deterioration from disease onset is more rapid than relapsing remitting and secondary progressive MS types. Multiple system involvement at onset and rapid early progression have a worse prognosis. PPMS can cause significant disability and impact on quality of life. Recent studies are biased in favour of relapsing remitting patients as treatment is now available for them and they are more likely to be seen at MS clinics. Since prognosis for PPMS is worse than other types of MS, the focus of rehabilitation is on managing disability and enhancing participation, and application of a “neuropalliative” approach as the disease progresses. This chapter presents the symptomatic treatment and rehabilitation for persons with MS, including PPMS. A multidisciplinary approach optimizes the intermediate and long-term medical, psychological and social outcomes in this population. Restoration and maintenance of functional independence and societal reintegration, and issues relating to quality of life are addressed in rehabilitation processes.

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