scholarly journals Kandungan Pestisida Organoklorin dalam Air Susu Ibu di Daerah Pertanian Bawang Merah Kabupaten Brebes

2018 ◽  
Vol 13 (1) ◽  
pp. 32 ◽  
Author(s):  
Dwi Cahyaningrum ◽  
Hanifa Maher Denny ◽  
Muh Sakundarno Adi

ABSTRAKPestisida organoklorin digunakan secara luas di pertanian pada waktu yang lampau. Zat ini mempunyai sifat persisten di lingkungan, memiliki kemampuan bioakumulasi dan biomagnifikasi dalam rantai makanan. Paparan organoklorin pada bayi sebelum lahir dapat menyebabkan kelahiran premature, abortus spontan, bahkan berdampak mengganggu fungsi system syaraf pusat. Wanita di daerah pertanian bawang merah beresiko tinggi terhadap paparan pestisida baik dari keterlibatan mereka di pertanian maupun paparan dari lingkungan. Air susu ibu adalah media yang sesuai untuk memantau paparan organoklorin pada manusia. Penelitian ini bertujuan untuk mengetahui kandungan pestisida organoklorin pada air susu ibu di daerah pertanian bawang merah Kabupaten Brebes, keterlibatan wanita di pertanian, dan keterkaitan beberapa faktor dengan konsentrasi organoklorin. Metode dan desain penelitian yang digunakan adalah deskriptif kualitatif dengan pendekatan cross sectional, dengan responden berjumlah 14 orang. Hasil penelitian menunjukkan sebanyak 4 responden mempunyai p’pDDE dengan konsentrasi >0,01 mg/kg (0,018-0,082 mg/kg) dan 11 responden mempunyai dieldrin dengan konsentrasi <0,01 mg/kg (0,001-0,007 mg/kg). Semakin meningkat nomor kelahiran, tingkat pengetahuan dan praktek penggunaan pestisida konsentrasi p’pDDE cenderung menurun. Kebiasaan makan ikan yang tercemar menjadi sumber paparan organoklorin pada wanita di daerah pertanian bawang merah Kabupaten Brebes. Kebijakan pengawasan penggunaan pestisida yang sekarang ada belum efektif untuk meningkatkan keamanan bekerja dengan pestisida pada petani.Kata Kunci : Organoklorin, ASI dan Keamanan bekerja dengan pestisidaABSTRACTTHE CONTENT OF ORGANOCHLORINE PESTICIDES IN HUMAN BREAST MILK IN ONION AGRICULTURA AREA AT BREBES DISTRICT; Organochlorine pesticides were widely used in agricultural at the past, these compounds are persistent in the environment and can be bioaccumulate and biomagnificate in food chain. Prenatal organochlorine exposure may lead to premature birth, spontaneous abortion and infere central nervous system function. Women living in agriculture area pose high risk of pesticides exposure resulting from their agriculture occupation and environment exposure. Breast milk could be a suitable matrix for monitoring organochlorine exposure in human. This study aimed to assess the content of organochlorine pesticides in human breast milk, women involvement in agricultural activity and factors related to the level of organochlorine compounds in breast milk. The qualitative descriptive method using cross sectional approach was applied in this research. There were 14 partisipants. The result demonstrated that 4 partisipans had p’pDDE level above 0,01 mg/kg (0,018-1,082), and 11 partisipans had level of Dieldrin below 0,01 mg/kg (0,001-0,007). Concentration p’pDDE tend to decreased as the increased of parity, level of knowledge, and level practices of pesticide. Dietary habits especially fish consumption was considered as a source of organochlorine exposure to human. Supervision policy the used of pesticide hasn’t effective yet to increase safe practices of pesticides among farmers.Keywords : Organochlorine, breast milk, safe practices of pesticides

2007 ◽  
Vol 9 (11) ◽  
pp. 1205 ◽  
Author(s):  
Boris Johnson-Restrepo ◽  
Rudolf Addink ◽  
Chung Wong ◽  
Kathleen Arcaro ◽  
Kurunthachalam Kannan

2015 ◽  
Vol 22 (12) ◽  
pp. 9293-9306 ◽  
Author(s):  
Dasheng Lu ◽  
Dongli Wang ◽  
Rong Ni ◽  
Yuanjie Lin ◽  
Chao Feng ◽  
...  

2019 ◽  
Vol 131 ◽  
pp. 104979 ◽  
Author(s):  
Raf Aerts ◽  
Ilse Van Overmeire ◽  
Ann Colles ◽  
Mirjana Andjelković ◽  
Govindan Malarvannan ◽  
...  

2020 ◽  
Vol 4 (7) ◽  
Author(s):  
Hiroshi M Ueno ◽  
Satoshi Higurashi ◽  
Yuzuka Shimomura ◽  
Ryota Wakui ◽  
Hiroaki Matsuura ◽  
...  

ABSTRACT Background DHA (22:6n–3) is essential for neurodevelopment in children, and its concentration in human breast milk is historically high in Japan. Dietary patterns in Japan might affect the fatty acid (FA) composition among lactating mothers. Objectives This study aimed to characterize the composition of milk FAs and to identify any dietary and sociodemographic factors associated with the variability of DHA concentration in breast milk in the Japanese population. Methods This cross-sectional study was performed as part of the Japanese Human Milk Study. Milk FAs were analyzed by GC at 1–6 mo postpartum, and maternal diet was estimated using an FFQ, including 11 types and cooking methods of seafoods, and the use of DHA supplements. The association of milk DHA with maternal diet and sociodemographic factors was investigated. Results Milk FA concentrations were measured in 78 mothers, including 24 who routinely used DHA supplements. The DHA concentration in milk (overall median: 0.62%; IQR: 0.47%–0.78%) was higher in women who took DHA supplements than in women who had never used DHA supplements (0.74%compared with 0.55%; P = 0.011). A linear regression model showed the association of milk DHA concentration with maternal dietary intake of grilled fish (β ± SE: 0.006 ± 0.003; standardized β: 0.234; r2 = 0.232, P = 0.036) after adjustment for DHA supplementation status, maternal and infant age, maternal BMI, and infant birth weight. Other FA concentrations were consistent, whereas caproic acid (6:0), undecylic acid (11:0), pentadecylic acid (15:0), palmitoleic acid (16:1n–7), and vaccenic acid (18:1n–7) varied by DHA supplementation status. Conclusions The DHA concentration in human milk may be influenced by maternal grilled fish consumption and frequent DHA supplementation in lactating Japanese women. Milk DHA concentrations may reflect a dietary habit in Japanese mothers. This trial was registered at www.umin.ac.jp/ctr as UMIN000015494.


Author(s):  
Ikewuchi Catherine ◽  
Kalaotaji Glory Biambo ◽  
Jonathan Nyebuchi ◽  
Amadi Chikadibia Fyneface ◽  
Nwika Goodnews

The human breast milk is considered to be the perfect food for infants, specifically adapted to their needs. Changes in lifestyle and environment may impact on breast milk composition. This study was aimed at comparing the nutrients composition in breast milk in postpartum women in urban and sub-urban areas in Rivers State. The cross-sectional study was conducted among 59 postpartum subjects between 0 and 10days of child delivery in each group. Sampling was done through a simple random sampling method. Human breast milk was collected by means of a manual breast pump for the analysis of carbohydrate, protein and lipid using ClegAnthrone Method, Kjedahl Method and Soxhelt Extraction Method respectively. The results revealed that carbohydrate level was 6.1±0.5% in urban group and 5.0±0.1% in sub-urban group which was statistically significant (t-value=2.2; p-value=0.04). Protein level was 3.5±0.6% in urban group and 3.9±0.3% in sub-urban group which was statistically non-significant (t-value=0.6; p-value=0.57).  Lipid level was 6.1±0.5% and 5.0±0.1% in urban and sub-urban groups respectively which was statistically non- significant (t-value=1.2; p-value=0.27). This study has revealed that differences in settlements (urban and sub-urban) have no impact on breast milk composition except in carbohydrate.


2012 ◽  
Vol 19 (04) ◽  
pp. 527-530
Author(s):  
SYED QAISER HUSAIN NAQVI ◽  
MOHAMMAD SHIRAZ KHAN ◽  
ALI AKBAR SIYAL ◽  
Mir Muhammad Sehto ◽  
Riaz Ahmed Qazi ◽  
...  

Objective: This study was aimed to see the significance of Lactoferrin in human breast milk among lactating mothers of healthyand sick babies. Place and duration: This study was conducted at pathology and paediatrics departments of Peoples University of Medical andHealth Sciences Nawabshah, Shaheed Benazirabad between Jan 2011 to Dec 2011. Design: Cross sectional study. Method: Lactoferrinlevels in breast milk of 356 mothers of healthy babies were estimated and similarly lactoferrin levels in breast milk of 318 lactating mothers ofsick babies were estimated & these results were analyzed. Results: the mean lactoferrin level in breast milk of 356 lactating mothers of healthybabies was 9.37 mg/ml and the mean lactoferrin level in breast milk of 318 mothers nursing sick babies was 3.73mg/ml. Conclusions: There isdecrease in lactoferrin levels of lactating mothers of sick babies in their mature milk, which could account for the susceptibility of their babies toinfection.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Seblework Mekonen ◽  
Argaw Ambelu ◽  
Mekitie Wondafrash ◽  
Patrick Kolsteren ◽  
Pieter Spanoghe

AbstractBreast milk is often used as an environmental bioindicator since it serves as an important medium to accumulate organochlorine pesticides. The main aim of this study is to determine the level of organochlorine pesticides in human breast milk collected from three districts of southwestern Ethiopia (Asendabo, Deneba, and Serbo) at three times points baselines (1st month), midline ( six months), and end line (12 months) and risk of infants’ exposure. A longitudinal study was conducted to assess pesticide residues in human breast milk samples and evaluate the risk-exposure of infants to these pesticides from consumption of mother’s milk in Ethiopia. Breast milk samples were collected from 168 mothers at three time points and pesticides were extracted using the quick, easy, cheap, effective, rugged, and safe (QuEChERS) method. The level of pesticide residues in human milk samples and exposure of infants to the pesticides was evaluated by calculating the estimated daily intake and compared with the provisional tolerable daily intake of the pesticides under study. The results indicated that, from the eight organochlorine pesticides analyzed in 447 breast milk samples at three sampling times, DDT and its metabolites were detected. p,p′-DDE and p,p′-DDT were detected in all (100%) of the breast milk samples while, p,p-DDD, and o,p-DDT were detected in 53.9%, and 42.7%, respectively. The mean concentration of total DDT at three time points(baseline, midline and endline) were 2.25, 1.68 and 1.32 µg/g milk fat, respectively. The mean concentration of total DDT from the three districts was 1.85 µg/g milk fat which is above the maximum residue limit (MRL = 0.02 µg/g milk fat set by FAO/WHO). The mean ratio of DDT/DDE for the three areas was calculated less than five (< 5) indicates historical DDT use in the study area. The estimated daily intake of infants at the first month of breastfeeding was 11.24 µg/kg-BW/day, above the provisional tolerable daily intake (PTDI) for total DDT set by FAO/WHO, which is 10 µg/kg body weight. An intake of OCPs is a big concern for infants' health in Ethiopia and countries with a similar condition, particularly at the first month of lactation. Strict regulations of the health-threatening pesticide by the regulatory body (Environment, Forest and Climate Change Commission) at the country and regional levels is advocated.


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