scholarly journals Restless Leg Syndrome and Sleep Disorders in Patients with Rheumatoid Arthritis and Its Relation with Anemia Parameters

2021 ◽  
Vol 64 (3) ◽  
pp. 137-144
Author(s):  
Salih Demir ◽  
Adem Kucuk ◽  
Mustafa Altas ◽  
Erkan Cure
Keyword(s):  
Quality Of Life ◽  
Rheumatoid Arthritis ◽  
Iron Deficiency ◽  
Sleep Quality ◽  
Sleep Disorders ◽  
Rating Scale ◽  
Binding Capacity ◽  
Anemia Of Chronic Disease ◽  
Healthy Control

Objectives: We aimed to investigate the prevalence of restless legs syndrome (RLS) and sleep disorders in patients with rheumatoid arthritis (RA), and the association of iron deficiency with them. Materials and methods: The study included 72 patients with RA (59 females, 13 males), and 50 healthy control subjects (57 females, 15 males). Assessments were made using the International RLS Rating Scale, Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale, Fatigue Severity Scale (FSS), Beck anxiety and depression index and the SF-36 quality of life scores. Results: We found that the frequency of RLS in RA patients was 29.1% and 13.8% in healthy control (p = 0.021). RA patients had 44.4% iron deficiency and 5.5% anemia of chronic disease. We found that 52.3% of patients with iron deficiency had RLS. There was an independent relationship between present of RLS and FSS (Beta [β] = 0.317, p = 0.005) and total iron binding capacity (TIBC) (β = 0.244, p = 0.031). There was an independent relationship between RLS severity score and PSQI (β = 0.264, p = 0.025) and social functionality (β = 0.302, p = 0.009). Conclusion: The prevalence of iron deficiency is high in RA in the developing countries. Analysis obtained in patients with RA is suggestive of an association between iron deficiency and increased frequency of RLS. The presence of RLS in patients with RA negatively affects sleep quality, psychiatric status, and quality of life of patients with RA. TIBC value may be a predictive marker for early detection of RLS in patients with RA.

scholarly journals Relationship between Sleep Disorders and Health Related Quality of Life—Results from the Georgia SOMNUS Study

2018 ◽  
Vol 15 (8) ◽  
pp. 1588 ◽  
Author(s):  
Nato Darchia ◽  
Nikoloz Oniani ◽  
Irine Sakhelashvili ◽  
Mariam Supatashvili ◽  
Tamar Basishvili ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Sleep Quality ◽  
Sleep Disorders ◽  
Developing World ◽  
Short Form ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Insomnia Severity

The extent to which sleep disorders are associated with impairment of health-related quality of life (HRQoL) is poorly described in the developing world. We investigated the prevalence and severity of various sleep disorders and their associations with HRQoL in an urban Georgian population. 395 volunteers (20–60 years) completed Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale, STOP-Bang questionnaire, Insomnia Severity Index, Beck Depression Inventory-Short Form, and Short Form Health Survey (SF-12). Socio-demographic data and body mass index (BMI) were obtained. The prevalence of sleep disorders and their association with HRQoL was considerable. All SF-12 components and physical and mental component summaries (PCS, MCS) were significantly lower in poor sleepers, subjects with daytime sleepiness, apnea risk, or insomnia. Insomnia and apnea severity were also associated with lower scores on most SF-12 dimensions. The effect of insomnia severity was more pronounced on MCS, while apnea severity—on PCS. Hierarchical analyses showed that after controlling for potential confounding factors (demographics, depression, BMI), sleep quality significantly increased model’s predictive power with an R2 change (ΔR2) by 3.5% for PCS (adjusted R2 = 0.27) and by 2.9% for MCS (adjusted R2 = 0.48); for the other SF-12 components ΔR2 ranged between 1.4% and 4.6%. ESS, STOP-Bang, ISI scores, all exerted clear effects on PCS and MCS in an individual regression models. Our results confirm and extend the findings of studies from Western societies and strongly support the importance of sleep for HRQoL. Elaboration of intervention programs designed to strengthen sleep-related health care and thereof HRQoL is especially important in the developing world.

Prevalence and Factors Associated With Fatigue in Patients With Inflammatory Bowel Disease: A Multicentre Study

2019 ◽  
Vol 13 (8) ◽  
pp. 996-1002 ◽  
Author(s):  
C Chavarría ◽  
M J Casanova ◽  
M Chaparro ◽  
M Barreiro-de Acosta ◽  
E Ezquiaga ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Inflammatory Bowel Disease ◽  
Sleep Quality ◽  
Multicentre Study ◽  
Sleep Disorders ◽  
Bowel Disease ◽  
Factors Associated ◽  
Increased Risk ◽  
Inflammatory Bowel

Abstract Background and Aims The aims of this study were to determine the prevalence of fatigue in patients with inflammatory bowel disease [IBD], to identify the factors associated with fatigue and its severity, to assess the impact of fatigue on quality of life [QoL], and to evaluate the relationship between fatigue and sleep disorders. Methods This was a prospective multicentre study conducted at 22 Spanish centres. Consecutive patients followed at IBD Units were included. Fatigue was evaluated with the Fatigue Severity Scale [FSS] and the Fatigue Impact Scale [FIS]. Quality of life and sleep quality were assessed using the IBD Questionnaire-Short Form [IBDQ-9] and the Pittsburgh Sleep Quality Index [PSQI], respectively. Results A total of 544 consecutive adult IBD patients were included [50% women, mean age 44 years, 61% Crohn’s disease]. The prevalence of fatigue was 41% (95% confidence interval [CI] = 37–45%). The variables associated with an increased risk of fatigue were: anxiety [OR = 2.5, 95% CI = 1.6–3.7], depression [OR = 2.4, 95% CI = 1.4–3.8], presence of extraintestinal manifestations [EIMs] [OR = 1.7, 95% CI = 1.1–2.6], and treatment with systemic steroids [OR = 2.8, 95% CI = 1.4–5.7]. The presence of EIMs [regression coefficient, RC = 8.2, 95% CI = 2.3–14.2], anxiety [RC = 25.8, 95% CI = 20.0–31.5], depression [RC = 30.6, 95% CI = 24.3–37.0], and sleep disturbances [RC = 15.0, 95% CI = 9.3–20.8] were associated with severity of fatigue. Patients with fatigue had a significantly decreased IBDQ-9 score [p < 0.001]. Conclusions The prevalence of fatigue in IBD patients is remarkably high and has a negative impact on QoL. Therapy with systemic steroids is associated with an increased risk of fatigue. The severity of fatigue is associated with anxiety, depression, sleep disorders, and the presence of EIMs. Fatigue was not associated with anaemia, disease activity or anti-TNF therapy.

scholarly journals Pain, depression levels, fatigue, sleep quality, and quality of life inelderly patients with rheumatoid arthritis

2017 ◽  
Vol 47 ◽  
pp. 847-853 ◽  
Author(s):  
İlknur ALBAYRAK GEZER ◽  
Ayşe BALKARLI ◽  
Beray CAN ◽  
Sinan BAĞÇACI ◽  
Sami KÜÇÜKŞEN ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Rheumatoid Arthritis ◽  
Sleep Quality

Effects of Sleep Quality on Health –Related Quality of Life in Rheumatoid Arthritis Patients at Zagazig University Hospitals.

2019 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Hala Abdel-Baset Abdel-Badea ◽  
Nagwa Ahmed Sherby ◽  
Ghada Mohamed Salah eldin ◽  
Mohamed Abd Allah Hammad
Keyword(s):  
Quality Of Life ◽  
Rheumatoid Arthritis ◽  
Sleep Quality ◽  
Health Related Quality ◽  
University Hospitals ◽  
Related Quality ◽  
Health Related

scholarly journals Relationship between Sleep Disorders, Pain and Quality of Life in Patients with Rheumatoid Arthritis

2015 ◽  
Vol 4 (3) ◽  
pp. 233-241 ◽  
Author(s):  
Majid Purabdollah ◽  
Sima Lakdizaji ◽  
Azad Rahmani ◽  
Mehrzad Hajalilu ◽  
Khalil Ansarin
Keyword(s):  
Quality Of Life ◽  
Rheumatoid Arthritis ◽  
Sleep Disorders

scholarly journals Relationship Between Sleep and Quality of Life in Older Adults With Mild Cognitive Impairment

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 619-619
Author(s):  
Darina Petrovsky ◽  
Miranda Varasse ◽  
Nancy Hodgson
Keyword(s):  
Quality Of Life ◽  
Older Adults ◽  
Cognitive Impairment ◽  
Sleep Quality ◽  
Daytime Sleepiness ◽  
Rating Scale ◽  
Sleep Onset ◽  
Community Dwelling ◽  
Subjective Sleep Quality

Abstract Our objective was to examine the independent relationship between sleep characteristics and quality of life (QOL) in community-dwelling older adults with cognitive impairment. Objective sleep variables were derived from actigraphy and included total sleep time, wake after sleep onset (WASO), efficiency, and number of awakenings. Subjective sleep quality was measured using Pittsburgh Sleep Quality Index and daytime sleepiness was measured with the Epworth Sleepiness Scale. Caregiver reported QOL-AD was used for QOL. Analyses included Spearman’s correlation and multivariate linear regression. In bivariate analyses, QOL was significantly related to clinical dementia rating scale, sex, depression, daytime sleepiness, sleep quality, WASO, and number of awakenings. Controlling for depression, daytime sleepiness remained independently associated with QOL (β= -0.24; p= 0.03). In addition, number of awakenings trended towards significance (β= -0.13; p= 0.07). Results suggest daytime sleepiness and awakenings are associated with QOL in this population.

scholarly journals Pallidal versus subthalamic deep-brain stimulation for meige syndrome: a retrospective study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jiayu Liu ◽  
Hu Ding ◽  
Ke Xu ◽  
Ruen Liu ◽  
Dongliang Wang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Sleep Quality ◽  
Rating Scale ◽  
Health Related Quality ◽  
Meige Syndrome ◽  
Related Quality ◽  
Health Related ◽  
Quality Status ◽  
Deep Brain

AbstractDeep-brain stimulation (DBS) is an effective treatment for patients with Meige syndrome. The globus pallidus interna (GPi) and the subthalamic nucleus (STN) are accepted targets for this treatment. We compared 12-month outcomes for patients who had undergone bilateral stimulation of the GPi or STN. Forty-two Asian patients with primary Meige syndrome who underwent GPi or STN neurostimulation were recruited between September 2017 and September 2019 at the Department of Neurosurgery, Peking University People’s Hospital. The primary outcome was the change in motor function, including the Burke–Fahn–Marsden Dystonia Rating Scale movement (BFMDRS-M) and disability subscale (BFMDRS-D) at 3 days before DBS (baseline) surgery and 1, 3, 6, and 12 months after surgery. Secondary outcomes included health-related quality of life, sleep quality status, depression severity, and anxiety severity at 3 days before and 12 months after DBS surgery. Adverse events during the 12 months were also recorded. Changes in BFMDRS-M and BFMDRS-D scores at 1, 3, 6, and 12 months with DBS and without medication did not significantly differ based on the stimulation target. There were also no significant differences in the changes in health-related quality of life (36-Item Short-Form General Health Survey) and sleep quality status (Pittsburgh Sleep Quality Index) at 12 months. However, there were larger improvements in the STN than the GPi group in mean score changes on the 17-item Hamilton depression rating scale (− 3.38 vs. − 0.33 points; P = 0.014) and 14-item Hamilton anxiety rating scale (− 3.43 vs. − 0.19 points; P < 0.001). There were no significant between-group differences in the frequency or type of serious adverse events. Patients with Meige syndrome had similar improvements in motor function, quality of life and sleep after either pallidal or subthalamic stimulation. Depression and anxiety factors may reasonably be included during the selection of DBS targets for Meige syndrome.

scholarly journals Sleep Disorders and Psychological Profile in Oral Cancer Survivors: A Case-Control Clinical Study

Cancers ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1855
Author(s):  
Roberta Gasparro ◽  
Elena Calabria ◽  
Noemi Coppola ◽  
Gaetano Marenzi ◽  
Gilberto Sammartino ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Sleep Quality ◽  
Cancer Survivors ◽  
Sleep Disorders ◽  
Rating Scales ◽  
Rating Scale ◽  
P Value ◽  
Early Assessment ◽  
Subjective Sleep Quality

Quality of sleep (QoS) and mood may impair oral cancer survivors’ wellbeing, however few evidences are currently available. Therefore, we aimed to assess the prevalence of sleep disorders, anxiety and depression among five-year oral cancer survivors (OC survivors). 50 OC survivors were compared with 50 healthy subjects matched for age and sex. The Pittsburgh Sleep Quality Index (PSQI), the Epworth Sleepiness Scale (ESS), the Hamilton Rating Scales for Depression and Anxiety (HAM-D, HAM-A), the Numeric Rating Scale (NRS), the Total Pain Rating Index (T-PRI) were administered. The global score of the PSQI, ESS, HAM-A, HAM-D, NRS, T-PRI, was statistically higher in the OC survivors than the controls (p-value: <0.001). QoS of OC survivors was significantly impaired, especially with regard to some PSQI sub-items as the subjective sleep quality, sleep latency and daytime dysfunction (p-value: 0.001, 0.029, 0.004). Moreover, poor QoS was negatively correlated with years of education (p-value: 0.042 *) and positively correlated with alcohol consumption (p-value: 0.049 *) and with the use of systemic medications (p-value: 0.044 *). Sleep disorders and mood disorders are common comorbidities in OC survivors; therefore, early assessment and management before, during and after treatment should be performed in order to improve the quality of life of OC survivors.

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