scholarly journals Pallidal versus subthalamic deep-brain stimulation for meige syndrome: a retrospective study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jiayu Liu ◽  
Hu Ding ◽  
Ke Xu ◽  
Ruen Liu ◽  
Dongliang Wang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Sleep Quality ◽  
Rating Scale ◽  
Health Related Quality ◽  
Meige Syndrome ◽  
Related Quality ◽  
Health Related ◽  
Quality Status ◽  
Deep Brain

AbstractDeep-brain stimulation (DBS) is an effective treatment for patients with Meige syndrome. The globus pallidus interna (GPi) and the subthalamic nucleus (STN) are accepted targets for this treatment. We compared 12-month outcomes for patients who had undergone bilateral stimulation of the GPi or STN. Forty-two Asian patients with primary Meige syndrome who underwent GPi or STN neurostimulation were recruited between September 2017 and September 2019 at the Department of Neurosurgery, Peking University People’s Hospital. The primary outcome was the change in motor function, including the Burke–Fahn–Marsden Dystonia Rating Scale movement (BFMDRS-M) and disability subscale (BFMDRS-D) at 3 days before DBS (baseline) surgery and 1, 3, 6, and 12 months after surgery. Secondary outcomes included health-related quality of life, sleep quality status, depression severity, and anxiety severity at 3 days before and 12 months after DBS surgery. Adverse events during the 12 months were also recorded. Changes in BFMDRS-M and BFMDRS-D scores at 1, 3, 6, and 12 months with DBS and without medication did not significantly differ based on the stimulation target. There were also no significant differences in the changes in health-related quality of life (36-Item Short-Form General Health Survey) and sleep quality status (Pittsburgh Sleep Quality Index) at 12 months. However, there were larger improvements in the STN than the GPi group in mean score changes on the 17-item Hamilton depression rating scale (− 3.38 vs. − 0.33 points; P = 0.014) and 14-item Hamilton anxiety rating scale (− 3.43 vs. − 0.19 points; P < 0.001). There were no significant between-group differences in the frequency or type of serious adverse events. Patients with Meige syndrome had similar improvements in motor function, quality of life and sleep after either pallidal or subthalamic stimulation. Depression and anxiety factors may reasonably be included during the selection of DBS targets for Meige syndrome.

Health-related qualıty of lıfe, sleep qualıty, and depressıon in peritoneal dialysis and hemodıalysıs patıents

2011 ◽  
Vol 16 (2) ◽  
pp. 198-206 ◽  
Author(s):  
Kultigin Turkmen ◽  
Raziye Yazici ◽  
Yalcin Solak ◽  
Ibrahim Guney ◽  
Lutfullah Altintepe ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Peritoneal Dialysis ◽  
Sleep Quality ◽  
Hemodialysis Patients ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

The role of basic psychological need satisfaction, sleep, and mindfulness in the health-related quality of life of people living with HIV

2016 ◽  
Vol 24 (4) ◽  
pp. 535-545 ◽  
Author(s):  
Rachel Campbell ◽  
Maarten Vansteenkiste ◽  
Liesbeth Delesie ◽  
Bart Soenens ◽  
Els Tobback ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Sleep Quality ◽  
Need Satisfaction ◽  
People Living With Hiv ◽  
Health Related Quality ◽  
Psychological Need ◽  
Related Quality ◽  
Health Related ◽  
Living With Hiv

Research has not yet examined the relationship between psychological need satisfaction, sleep, mindfulness, and health-related quality of life in people living with HIV. This cross-sectional study ( N = 101; 84% male; mean age = 45.48, SD = 12.75) found need satisfaction to relate positively to physical and mental health. Sleep quality fully mediated the association with physical health and partially mediated the association with mental health. Furthermore, mindfulness related to higher sleep quality through higher need satisfaction. Findings underscore the role of need satisfaction in determining health-related quality of life and sleep quality in people living with HIV and suggest that mindfulness may facilitate need satisfaction.

O107 Depressive symptoms mediate the relationship between sleep quality and health-related quality of life in heart failure

Global Heart ◽  
2014 ◽  
Vol 9 (1) ◽  
pp. e29
Author(s):  
An-Yun Yeh ◽  
Susan J. Pressler ◽  
Seongkum Heo ◽  
Debra K. Moser ◽  
Sandra B. Dunbar ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Depressive Symptoms ◽  
Sleep Quality ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
The Relationship

scholarly journals Health-related quality of life of middle-aged and elderly people with hypertension: A cross-sectional survey from a rural area in China

PLoS ONE ◽  
2021 ◽  
Vol 16 (2) ◽  
pp. e0246409
Author(s):  
Qi Chen ◽  
Li Ran ◽  
Mengying Li ◽  
Xiaodong Tan
Keyword(s):  
Quality Of Life ◽  
Sleep Quality ◽  
Moderate Physical Activity ◽  
Health Related Quality ◽  
Middle Aged ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Related Quality ◽  
Health Related

Objective To evaluate health-related quality of life (HRQoL) of middle-aged and elderly people with hypertension in Enshi, China, and to explore the important correlates defining HRQoL. Methods From April through July 2018, a self-monitoring intervention program for hypertension control was implemented in a remote area of central China. Participants completed a cross-sectional survey which included demographic characteristics, the Health-related Quality of Life Survey, and the Pittsburgh Sleep Quality Index Survey. Univariate analysis was performed by analysis of variance, and multiple linear regression analysis was used to analyze the influencing factors of HRQoL in middle-aged and elderly hypertensive patients. In the multivariate analysis, the variables with P≤0.05 in the single factor analysis were combined with the professional significance to establish a multiple linear regression model. Results Information from 500 participants was available for analysis. Among them, the scores of PCS and MCS was 31.66 ± 9.50 and 41.38 ± 10.69, respectively. Multivariable regression analyses showed that higher education and sleep quality, and moderate physical activity (30 minutes for at least five days a week) had a positive influence on PCS scores. Higher monthly family income (3,000–5,000 ¥) and sleep quality, regular tea-drinking, having 30 minutes of moderate physical activity at least five days a week were positively associated with MCS scores. Conclusion The overall HRQoL for rural middle-aged and elderly hypertensive patients in Xuan’en county of Hubei province was poor. Effective relevant measures for the above factors were urgently needed to improve the quality of life for the elderly in rural areas. Awareness of these relevant factors could help health care professionals provide better supportive care.

scholarly journals Association between ongoing pain intensity, health-related quality of life, disability and quality of sleep in elderly people with total knee arthroplasty

2014 ◽  
Vol 19 (6) ◽  
pp. 1881-1888 ◽  
Author(s):  
María Dolores Herrero-Sánchez ◽  
María del Carmen García-Iñigo ◽  
Blanca Soledad Nuño-Beato-Redondo ◽  
César Fernández-de-las-Peñas ◽  
Francisco Alburquerque-Sendín
Keyword(s):  
Quality Of Life ◽  
Total Knee Arthroplasty ◽  
Sleep Quality ◽  
Pain Intensity ◽  
Social Role ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Total Knee

The scope of this paper was to study the relationship between pain intensity, health-related quality of life, disability, sleep quality and demographic data in elderly people with total knee arthroplasty (TKA). 24 subjects who had been subjected to TKA the previous month (4 females; 66 ± 9years) and 21 comparable controls (8 male; 70 ± 9years) participated in the study. Intensity of pain, and highest and lowest pain intensity experienced in the preceding week were collected. The Western Ontario and McMaster Universities index function, quality of life (Medical Outcomes Study Short Form 36), and Pittsburgh Sleep Quality Index were assessed. Age, gender, weight, height, body mass index were also collected. Individuals with TKA presented worse physical function (P < 0.01), social role (P = 0.01), physical performance (P < 0.01), pain (P = 0.04), disability (P = 0.04) and sleep quality (P = 0.03) than the controls. Higher intensity of pain was associated with lower physical function, social role, mental health, vitality and general health, and with higher disability and sleep quality. Disability and sleep quality were negatively associated with several quality of life domains. The associations between the intensity of pain, disability, quality of life and sleep reveal the multidimensional experience of TKA.

scholarly journals Relationship between Sleep Disorders and Health Related Quality of Life—Results from the Georgia SOMNUS Study

2018 ◽  
Vol 15 (8) ◽  
pp. 1588 ◽  
Author(s):  
Nato Darchia ◽  
Nikoloz Oniani ◽  
Irine Sakhelashvili ◽  
Mariam Supatashvili ◽  
Tamar Basishvili ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Sleep Quality ◽  
Sleep Disorders ◽  
Developing World ◽  
Short Form ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Insomnia Severity

The extent to which sleep disorders are associated with impairment of health-related quality of life (HRQoL) is poorly described in the developing world. We investigated the prevalence and severity of various sleep disorders and their associations with HRQoL in an urban Georgian population. 395 volunteers (20–60 years) completed Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale, STOP-Bang questionnaire, Insomnia Severity Index, Beck Depression Inventory-Short Form, and Short Form Health Survey (SF-12). Socio-demographic data and body mass index (BMI) were obtained. The prevalence of sleep disorders and their association with HRQoL was considerable. All SF-12 components and physical and mental component summaries (PCS, MCS) were significantly lower in poor sleepers, subjects with daytime sleepiness, apnea risk, or insomnia. Insomnia and apnea severity were also associated with lower scores on most SF-12 dimensions. The effect of insomnia severity was more pronounced on MCS, while apnea severity—on PCS. Hierarchical analyses showed that after controlling for potential confounding factors (demographics, depression, BMI), sleep quality significantly increased model’s predictive power with an R2 change (ΔR2) by 3.5% for PCS (adjusted R2 = 0.27) and by 2.9% for MCS (adjusted R2 = 0.48); for the other SF-12 components ΔR2 ranged between 1.4% and 4.6%. ESS, STOP-Bang, ISI scores, all exerted clear effects on PCS and MCS in an individual regression models. Our results confirm and extend the findings of studies from Western societies and strongly support the importance of sleep for HRQoL. Elaboration of intervention programs designed to strengthen sleep-related health care and thereof HRQoL is especially important in the developing world.

scholarly journals Determinants of Health-related Quality of Life in Recently Detoxified Patients With Severe Alcohol Use Disorder

2021 ◽  
Author(s):  
Najlaa Lahbairi ◽  
Alice Laniepce ◽  
Shailendra Segobin ◽  
Nicolas Cabé ◽  
Céline Boudehent ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Alcohol Use ◽  
Sleep Quality ◽  
Alcohol Use Disorder ◽  
Treatment Success ◽  
Health Related Quality ◽  
Quality Of Life Scale ◽  
Related Quality ◽  
Health Related

Abstract Background. Health-related quality of life (HRQoL) is an important clinical outcome in Alcohol Use Disorder (AUD) and is considered as a relevant indicator of treatment success. While a better understanding of the factors affecting HRQoL would enable to adjust patients’ care to favour treatment outcome, the determinants of HRQoL in AUD remain unclear. This study aims at describing HRQoL in AUD patients and at identifying its best predictors. Methods. We included 53 recently detoxified patients with severe AUD (sAUD) and 38 healthy controls (HC). They underwent a cognitive assessment and filled in questionnaires concerning socio-demographics, alcohol history, sleep quality, depression, anxiety and impulsivity. Additionally, a HRQoL questionnaire especially designed for AUD patients (Alcohol Quality of Life Scale; AQoLS) was used.Results. sAUD patients reported that alcohol affects their HRQoL mainly in the “negative emotions”, “control”, “relationships”, and “sleep” domains. Compared to HC, they were impaired on episodic memory, working memory, executive functions, and processing speed tasks. They also reported lower sleep quality, higher depression, anxiety and impulsivity. No association was found between AQoLS total score and socio-demographics, cognitive performance, or sleep quality in patients. We found a significant correlation between HRQoL and depression/anxiety as well as impulsivity. Anxiety and impulsivity were indeed the only significant predictors of HRQoL, explaining 47.7% of the variance. Conclusions. Anxiety and impulsivity are crucial determinants of HRQoL in recently detoxified sAUD patients. Since anxiety and impulsivity are frequent issues in addiction and especially in AUD, they should be particularly considered by clinicians to favour treatment outcomes.

Impact of Restless Leg Syndrome on Fatigue and Quality of Life Among Hemodialysis Patients

2021 ◽  
Vol 4 (1) ◽  
pp. 17-21
Author(s):  
Saad Ali Nasir ◽  
Fareeha Amjad ◽  
Sana Rafaqat
Keyword(s):  
Quality Of Life ◽  
Rating Scale ◽  
Hemodialysis Patients ◽  
Activity Level ◽  
Moderate Activity ◽  
Health Related Quality ◽  
Restless Leg Syndrome ◽  
Related Quality ◽  
Health Related

Abstract:Restless Legs Syndrome (RLS) is a sensorymotor sleep disorder which his very common in hemodialysis (HD) patients. It is called also as uremic RLS and it is affecting almost 30%of the HD population. Objective: To find out impact of Restless Leg Syndrome on fatigue and quality of life in patients of hemodialysis.Methadology: 131 hemodialysis patients (male, female) were approached from different hospitals in Lahore. Demographic data of the patients were collected. Questionnaires were included Fatigue Severity Scale, Restless Legs Syndrome Questionnaire (Rating Scale) and health quality questionnaire SF-12®. All responses entered in SPSS version 21.Results: In this survey SF12 was used to nd about health related quality of life in patients with RLS and undergoing hemodialysis and fatigue was observed in (n-75%) patients with exercise, (n34%) reported fatigue interference with work and (n-22%) reported fatigue was constant problem. Quality of life was overall poor as (n-72 %) patient's complaint that they cannot do any kind of work with full focus and 34 % reported their moderate activity level was limited.Conclusion: RLS was frequent in patients with hemodialysis. it had an association with fatigue and poor quality of life. As hemodialysis patients spend most of their time on bed RLS has negative impact on the sleep. Health Related Quality Of Life affects both physical and mental health.Keywords: Restless Leg Syndrome, Fatigue, low quality oflife, Hemodialysis patients

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