Sleep Disorders and Psychological Profile in Oral Cancer Survivors: A Case-Control Clinical Study

Quality of sleep (QoS) and mood may impair oral cancer survivors’ wellbeing, however few evidences are currently available. Therefore, we aimed to assess the prevalence of sleep disorders, anxiety and depression among five-year oral cancer survivors (OC survivors). 50 OC survivors were compared with 50 healthy subjects matched for age and sex. The Pittsburgh Sleep Quality Index (PSQI), the Epworth Sleepiness Scale (ESS), the Hamilton Rating Scales for Depression and Anxiety (HAM-D, HAM-A), the Numeric Rating Scale (NRS), the Total Pain Rating Index (T-PRI) were administered. The global score of the PSQI, ESS, HAM-A, HAM-D, NRS, T-PRI, was statistically higher in the OC survivors than the controls (p-value: <0.001). QoS of OC survivors was significantly impaired, especially with regard to some PSQI sub-items as the subjective sleep quality, sleep latency and daytime dysfunction (p-value: 0.001, 0.029, 0.004). Moreover, poor QoS was negatively correlated with years of education (p-value: 0.042 *) and positively correlated with alcohol consumption (p-value: 0.049 *) and with the use of systemic medications (p-value: 0.044 *). Sleep disorders and mood disorders are common comorbidities in OC survivors; therefore, early assessment and management before, during and after treatment should be performed in order to improve the quality of life of OC survivors.

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Post-caesarean section pain and quality of sleep among mothers who delivered by caesarean section under spinal anesthesia

Malahayati International Journal of Nursing and Health Science ◽

10.33024/minh.v3i2.3473 ◽

2021 ◽

Vol 3 (2) ◽

pp. 110-116

Author(s):

Ririn Harini ◽

Juwitasari Juwitasari ◽

Lilis Setyowati ◽

Rifdah Dita Oktavia

Keyword(s):

Caesarean Section ◽

Sleep Quality ◽

Rating Scale ◽

Healing Process ◽

Numeric Rating Scale ◽

Wound Healing Process ◽

P Value ◽

Poor Sleep ◽

Pain Level

Background: Post caesarean section mothers commonly feel pain in the post-operative area during the wound healing process. Most post-operative mothers feel the pain sensation as a disturbance and lowering their quality of sleep.Purpose: To determine pain level and identify the relationship of pain level and sleep quality among mothers who delivered by caesarean section under spinal anaesthesia.Method: The descriptive non-experimental correlative study design identified 50 mothers from Inpatient Ward Wava Husada Hospital of Kepanjen, Malang, East Java, Indonesia at April 2020. The Post-caesarean section pain level identified by using the Numeric Rating Scale (NRS) and the sleep quality is measured using Pittsburgh Sleep Quality Index (PSQI) questionnaire.Results: 38 mothers (76%) had severe pain level and most of them (43 mothers) had poor sleep quality. The Spearman correlation test showed that there was a relationship between the Post-caesarean section pain level and sleep quality, p value = 0.000 (p <0.05) and r = 0.314.Conclusion: The post-caesarean section pain levels among mothers who delivered by caesarean section under spinal anaesthesia should be identified earlier as we would like to encourage the nursing staff to give further intervention to maintain their sleep quality.

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Relationship Between Sleep and Quality of Life in Older Adults With Mild Cognitive Impairment

Innovation in Aging ◽

10.1093/geroni/igaa057.2107 ◽

2020 ◽

Vol 4 (Supplement_1) ◽

pp. 619-619

Author(s):

Darina Petrovsky ◽

Miranda Varasse ◽

Nancy Hodgson

Keyword(s):

Quality Of Life ◽

Older Adults ◽

Cognitive Impairment ◽

Sleep Quality ◽

Daytime Sleepiness ◽

Rating Scale ◽

Sleep Onset ◽

Community Dwelling ◽

Subjective Sleep Quality

Abstract Our objective was to examine the independent relationship between sleep characteristics and quality of life (QOL) in community-dwelling older adults with cognitive impairment. Objective sleep variables were derived from actigraphy and included total sleep time, wake after sleep onset (WASO), efficiency, and number of awakenings. Subjective sleep quality was measured using Pittsburgh Sleep Quality Index and daytime sleepiness was measured with the Epworth Sleepiness Scale. Caregiver reported QOL-AD was used for QOL. Analyses included Spearman’s correlation and multivariate linear regression. In bivariate analyses, QOL was significantly related to clinical dementia rating scale, sex, depression, daytime sleepiness, sleep quality, WASO, and number of awakenings. Controlling for depression, daytime sleepiness remained independently associated with QOL (β= -0.24; p= 0.03). In addition, number of awakenings trended towards significance (β= -0.13; p= 0.07). Results suggest daytime sleepiness and awakenings are associated with QOL in this population.

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Efektivitas Baby Massage Dan Baby Gym Terhadap Kualitas Tidur Bayi Usia 3-6 Bulan

Jurnal SMART Kebidanan ◽

10.34310/sjkb.v8i1.441 ◽

2021 ◽

Vol 8 (1) ◽

pp. 6

Author(s):

Rose Nurhudariani ◽

Yeni Dwi Ratnasari ◽

Sonhaji Sonhaji ◽

Siti Nur Umariyah Febriyanti

Keyword(s):

Sleep Quality ◽

Sleep Disorders ◽

Sleep Disturbances ◽

Sleep Problems ◽

P Value ◽

Test Design ◽

Quality Of Sleep ◽

Post Test ◽

A Minor

Baby massage dan baby gym adalah upaya untuk meningkatkan kualitas tidur pada bayi. Masalah tidur pada bayi di Indonesia cukup banyak, yaitu sekitar 44,2% bayi mengalami gangguan tidur seperti sering terbangun di malam hari. Namun lebih dari 72% orang tua menganggap gangguan tidur bukan suatu masalah atau hanya masalah kecil, hal tersebut diungkapkan oleh sebuah penelitian pada tahun 2014-2015 yang dilaksanakan di lima kota besar di Indonesia Berdasarkan data awal terdapat 20 bayi yang datang ke posyandu dan ditemukan 17 bayi yang mengalami gangguan tidur. Tujuan penelitian untuk mengetahui efektivitas baby massage dan baby gym terhadap kualitas tidur bayi usia 3-6 bulan di Desa Talang Tegal. Jenis penelitian adalah kuantitatif dengan two group pre and post test design. Sampel sebanyak 34 bayi yang diberikan perlakuan baby massage dan baby gym dilakukan selama 2 minggu 3x seminggu, untuk baby massage 15 menit sedangkan untuk baby gym 5 menit. Terdapat pengaruh baby massage terhadap kualitas tidur bayi usia 3-6 bulan dengan p value 0.000. Terdapat pengaruh baby gym terhadap kualitas tidur bayi usia 3-6 bulan dengan p value 0,001. Tidak terdapat perbedaan efektivitas baby massage dan baby gym terhadap kualitas tidur bayi usia 3 – 6 bulan. Kata kunci : baby gym; baby massage; kualitas tidur bayi The Effectiveness of Baby Massage And Baby Gym on Sleep Quality of 3-6 Months Baby ABSTRACT Baby massage and baby gym are efforts to improve the quality of sleep in babies. There are quite a number of sleep problems in infants in Indonesia, which is around 44.2% of infants experiencing sleep disorders such as frequent awakenings at night. However, more than 72% of parents consider sleep disturbances not a problem or just a minor problem, this was revealed by a 2014-2015 study conducted in five major cities in Indonesia. Based on initial data there were 20 babies who came to the Integrated Healthcare Centre and found 17 babies with sleep disorders. The purpose of the study was to determine the effectiveness of baby massage and baby gym on the sleep quality of baby aged 3-6 months in Talang Tegal Village. This type of research was quantitative with two groups pre-post test design. A sample of 34 babies who were given baby massage and baby gym treatment was carried out for 2 weeks 3 time each week, for baby massage 15 minutes while for baby gym 5 minutes. There is an effect of baby massage on the sleep quality of babies aged 3-6 months with a p value of 0.000. There is an effect of baby gym on the sleep quality of babies aged 3-6 months with a p value of 0.001. There is no difference in the effectiveness of baby massage and baby gym on the sleep quality of babies aged 3-6 months. Keywords: baby gym; baby massages; sleep quality of baby

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The Epidemiology of Subjective Sleep Quality in the Citizens of Kermanshah, Iran

Journal of Kermanshah University of Medical Sciences ◽

10.5812/jkums.100040 ◽

2020 ◽

Vol 24 (2) ◽

Author(s):

Keivan Kakabaraee ◽

Habibolah Khazaie ◽

Azita Chehri ◽

Maryam Seidy

Keyword(s):

Quality Of Life ◽

Sleep Quality ◽

Sleep Disorders ◽

Self Report ◽

Poor Sleep ◽

Subjective Sleep Quality ◽

Cross Sectional ◽

Subjective Sleep ◽

High Doses

Background: Subjective sleep quality plays a pivotal role in health, quality of life, and efficient performance. Objectives: The present study aimed to investigate the epidemiology of subjective sleep quality in the citizens of Kermanshah, Iran. Methods: This cross-sectional, descriptive study was conducted on all the citizens of Kermanshah in 2017. In total, 450 subjects were selected via multistage random sampling. Based on the inclusion criteria, 416 were evaluated using a self-report questionnaire of demographic characteristics and Petersburg sleep quality index (PSQI; Baisi et al., 1989). Results: In 79% of the participants, the mean score of PSQI was above the cutoff point (m = 6.64). The analysis of the questionnaires indicated the highest frequency of sleep disorders to be in the components of subjective sleep quality from the perspective of the respondents, delayed sleep, sleep disorders, and daily functional disorders. In addition, 10.6% of the subjects used very high doses of sedatives, while 10.3% used relatively high doses of these pills. Minimal sleep disorders were reported as well. Poor sleep quality was less common in women, and significant correlations were observed between age and sleep latency, sleep duration, sleep medication use, and daytime dysfunction due to sleepiness. Conclusions: According to the results, subjective sleep quality was favorable in the citizens of Kermanshah. Considering the significant effects of sleep quality on performance and quality of life, attention must be paid to this aspect of health by healthcare planners and managers.

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Quantitative oculomotor and nonmotor assessments in late-onset GM2 gangliosidosis

Neurology ◽

10.1212/wnl.0000000000008959 ◽

2020 ◽

Vol 94 (7) ◽

pp. e705-e717

Author(s):

Christopher D. Stephen ◽

David Balkwill ◽

Peter James ◽

Elizabeth Haxton ◽

Kenneth Sassower ◽

...

Keyword(s):

Sleep Quality ◽

Disease Severity ◽

Rating Scales ◽

Rating Scale ◽

Late Onset ◽

Gm2 Gangliosidosis ◽

Subjective Sleep Quality ◽

Cross Sectional ◽

Subjective Sleep ◽

Oculomotor Abnormalities

ObjectiveA cross-sectional study was performed to evaluate whether quantitative oculomotor measures correlate with disease severity in late-onset GM2 gangliosidosis (LOGG) and assess cognition and sleep as potential early nonmotor features.MethodsTen patients with LOGG underwent quantitative oculomotor recordings, including measurements of the angular vestibulo-ocular reflex (VOR), with results compared to age- and sex-matched controls. Disease severity was assessed by ataxia rating scales. Cognitive/neuropsychiatric features were assessed by the cerebellar cognitive affective syndrome (CCAS) scale, Cerebellar Neuropsychiatric Rating Scale, and sleep quality evaluated using subjective sleep scales.ResultsOculomotor abnormalities were found in all participants, including 3/10 with clinically normal eye movements. Abnormalities involved impaired saccadic accuracy (5/10), abnormal vertical (8/10) and horizontal (4/10) pursuit, reduced optokinetic nystagmus (OKN) responses (7/10), low VOR gain (10/10), and impaired VOR cancellation (2/10). Compared to controls, the LOGG group showed significant differences in saccade, VOR, OKN, and visually enhanced VOR gains. Severity of saccadic dysmetria, OKN, and VOR fixation-suppression impairments correlated with ataxia scales (p < 0.05). Nine out of ten patients with LOGG had evidence of the CCAS (5/10 definite, 2/10 probable, 2/10 possible). Excessive daytime sleepiness was present in 4/10 and 8/10 had poor subjective sleep quality.ConclusionsCerebellar oculomotor abnormalities were present in all patients with LOGG, including those with normal clinical oculomotor examinations. Saccade accuracy (dorsal cerebellar vermis localization), fixation suppression, and OKN gain (cerebellar flocculus/paraflocculus localization) correlated with disease severity, suggesting that quantitative oculomotor measurements could be used to track disease progression. We found evidence of the CCAS, suggesting that cerebellar dysfunction may explain the cognitive disorder in LOGG. Sleep impairments were prevalent and require further study.

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1121 Nonmotor Symptoms Affect Sleep Quality in Early-Stage Parkinson’s Disease Patients With or Without Cognitive Dysfunction

SLEEP ◽

10.1093/sleep/zsaa056.1116 ◽

2020 ◽

Vol 43 (Supplement_1) ◽

pp. A427-A427

Author(s):

L Zhang ◽

J Zhu

Keyword(s):

Sleep Quality ◽

Sleep Disorders ◽

Cognitive Dysfunction ◽

Sleep Disturbances ◽

Rating Scale ◽

Early Stage ◽

Motor Symptoms ◽

Nonmotor Symptoms ◽

Subjective Sleep Quality ◽

Subjective Sleep

Abstract Introduction Parkinson’s disease (PD) patients frequently present with sleep disorders. This study was designed to assess the impact of nonmotor symptoms (NMSs) on subjective sleep quality in early-stage PD patients with and without cognitive dysfunction. Methods A sample of 389 early-stage PD patients (Hoehn and Yahr score ≤2.5, duration ≤5 years) was recruited for the present study. The Non-Motor Symptoms Questionnaire (NMS-Quest) was used to screen for global NMSs. Depressive symptoms were assessed using the Hamilton Rating Scale for Depression (HAMD). PD motor symptoms were measured with the Unified PD Rating Scale (UPDRS), part III. The Montreal Cognitive Assessment (MoCA) was used to evaluate global cognitive status, and the PD Sleep Scale (PDSS) was used to quantify sleep quality. Logistic regression models were built to identify factors associated with sleep disturbances. Results In our sample, approximately one-quarter of the PD patients suffered from sleep disturbances (23.7%). Our results also confirmed the high prevalence of cognitive dysfunction in patients with PD (39.8%). In total, the patients who suffered from NMSs, such as depressive symptoms, anxiety symptoms, urinary tract symptoms and hallucinations/delusions, had poorer sleep quality. Better cognition may protect against sleep disorders. In patients with cognitive dysfunction, the NMS-Hallucinations/delusions score was the most important risk factor for sleep disorders. In patients without cognitive dysfunction, NMSs such as anxiety and cognition and medication were related to sleep disorder. Conclusion NMSs in early-stage PD are highly associated with and are determinants of subjective sleep quality. Future studies should focus on elucidating the pathophysiology of these symptoms. Support Special Funds of the Jiangsu Provincial Key Research and Development Projects (grant No. BE2018610)

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Pengaruh Terapi Murrotal Al-Qur’an terhadap Kualitas Tidur Bayi Usia 3-6 Bulan

Window of Midwifery Journal ◽

10.33096/wom.vi.12 ◽

2020 ◽

pp. 24-30

Author(s):

Citra Amalu ◽

Maftuchah ◽

Fitria Hikmatul Ulya

Keyword(s):

Sleep Quality ◽

Sleep Disorders ◽

Test Data ◽

Growth And Development ◽

Statistical Test ◽

P Value ◽

Study Population ◽

Independent Variable ◽

Sampling Variable

Kebutuhan tidur tidak hanya dapat dilihat dari aspek kuantitas tidur tapi dapat juga dilihat dari kualitas tidur bayi. Jika kualitas tidur bayi baik, maka pertumbuhan dan perkembangan bayi dapat dicapai secara optimal, salah satu cara untuk memperbaiki kualitas tidur bayi yaitu dengan cara terapi murrotal Al-Qur’an. Dari wawancara 12 orang tua, didapatkan 8 bayi yang memiliki gangguan tidur. Penelitian ini bertujuan untuk mendeskripsikan pengaruh terapi murrotal Al-Qur’an terhadap kualitas tidur bayi usia 3-6 bulan. Jenis penelitian ini adalah quasi experimen dengan rancangan one group pretest-posttest design. Populasi penelitian ini adalah bayi yang berusia 3-6 bulan dengan gangguan tidur. Penelitian ini dilakukan sehari 2 kali dan diberikan setiap menjelang tidur. Sampel penelitian 16 bayi yang berusia 3-6 bulan, secara purpossive sampling. Variable independent terapi murrotal Al-Qur’an dan variable dependent kualitas tidur bayi usia 3-6 bulan. Instrument penelitian menggunakan kuesioner. Pengolahan data uji statistic Wilcoxon. Asym. Sig (p-value 0.000) (< 0,05), Ha diterima dan Ho ditolak atau ada pengaruh sebelum diberikan terapi murrotal Al-Qur’an dan sesudah diberikan terapi murrotal Al-Qur’an terhadap peningkatan kualitas tidur pada bayi usia 3-6 bulan. Kesimpulan penelitian dari penelitian ini ada Pengaruh Terapi Murrotal Al-Qur’an Terhadap Kualitas Tidur Bayi Usia 3-6 Bulan Di Kelurahan Meteseh Kota Semarang. Sleep needs can not only be seen from the aspect of the quantity of sleep but can also be seen from the quality of baby's sleep. If the sleep quality of the baby is good, then the growth and development of the baby can be achieved optimally, one way to improve the quality of baby's sleep is by means of the Murrotal Al-Qur'an therapy. From interviews of 12 parents, found 8 babies who have sleep disorders. This study aims to describe the influence of Al-Qur'an mass therapy on sleep quality of infants aged 3-6 months. This type of research is a quasi experiment with one group pretest-posttest design. The study population was infants aged 3-6 months with sleep disorders. This research was conducted twice a day and given every time before bedtime. Study sample 16 infants aged 3-6 months, using purposive sampling. The independent variable is Murrotal Al-Qur'an and the dependent variable is sleep quality of infants aged 3-6 months. The research instrument used a questionnaire. Processing of Wilcoxon statistical test data. Asym. Sig (p-value 0.000) (<0.05), Ha is accepted and Ho is rejected or there is an influence before being given the Murrotal Al-Qur'an therapy and after being given the Murrotal Al-Qur'an therapy on improving sleep quality in infants aged 3- 6 months. The conclusion of this research is the Effect of Al-Qur'an Murrotal Therapy on Sleep Quality of Infants Age 3-6 Months in Meteseh Village, Semarang City.

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HUBUNGAN LATIHAN RELAKSASI OTOT PROGRESIF DENGAN KUALITAS TIDUR PADA LANSIA

Jurnal Ilmiah PANNMED (Pharmacist, Analyst, Nurse, Nutrition, Midwivery, Environment, Dentist) ◽

10.36911/pannmed.v15i2.753 ◽

2020 ◽

Vol 15 (2) ◽

pp. 289-295

Author(s):

Kiki Anggini

Keyword(s):

Sleep Quality ◽

Sleep Disorders ◽

Muscle Relaxation ◽

The Elderly ◽

Progressive Muscle Relaxation ◽

P Value ◽

Quality Of Sleep ◽

Experiment Method ◽

Relaxation Exercises

ABSTRACT Insomnia sleep disorders that distrupt a person’s concentrartion causing insomnia or insufficient sleep, resulting in inefficient sleep. Cause stress if it continues to have an impact on anxiety, headaches, sexual decline in men, worsening vision, lack of concentration, fatigue, and anemia (Suci, 2014). The aim is to find out whether there is a relationship between progressive muscle relaxation exercises and sleep quality in the elderly at the Guna Budi Bakti Medan Foundation in 2020. This research uses quasy experiment method and uses one grub pretest posttest design, which uses two sample groups be interviewed before (pretest) and after (posttest) by filling out the questionnaire. Based on the results of the Wilcoxon signedrank test, that the value of Z = -4,256ᵇ with a p value of 0,000 <0.05, the Ha is accepted and the Ho is rejected. It was concluded that there was an improvement in the quality of sleep in the elderly by doing progressive muscle relaxation exercises. Hopefully this research can improve the quality of nurses working in institutions capable of applying progressive muscle relaxation exercises in the elderly. ABSTRAK Insomnia adalah gangguan tidur yang mengganggu konsentrasi seseorang menyebabkan sulit tidur atau tidak cukup tidur , sehingga waktu tidur tidak efesien. Menyebabkan stres apabila berkelanjutan berdampak pada kecemasan, sakit kepala, penurunan seksual pada pria, penglihatan memburuk, tidak konsentrasi, mudah lelah, dan anemia (Suci, 2014). Tujuan untuk mengetahui adakah hubungan latihan relaksasi otot progresif dengan kualitas tidur pada lansia di Yayasan Guna Budi Bakti Medan tahun 2020”. Penelitian ini menggunakan metode Quasy Eksperiment dan memakai rancangan One Group Pretest Posttest, yaitu menggunakan 2 kelompok sampel diwawancara sebelum (pretest) dan sesudah (possttest) dengan mengisi kuisioner (Soekijo Notoatmojo,2017).Berdasarkan hasil perhitungan wilcoxon signedrank test, bahwa nilai Z=-4.256ᵇ dengan nilai p value 0,000 <0,05 maka Ha diterima dan Ho ditolak. Disimpulkan bahwa terdapat peningkatan kualitas tidur pada lanjut usia dengan melakukan latihan relaksasi otot progresif. Semoga penelitian ini dapat meningkatkan kualitas perawat yang bekerja di panti mampu mengaplikasikan latihan relaksasi otot progresif pada lansia.

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THE RELATIONSHIP BETWEEN ANXIETY LEVELS THROUGH SLEEP QUALITY OF WIJAYA HUSADA NURSING STUDENTS

Jurnal Ilmiah Wijaya ◽

10.46508/jiw.v11i1.38 ◽

2020 ◽

Vol 11 (1) ◽

pp. 55-65

Author(s):

Julianto Julianto Laia

Keyword(s):

Nursing Students ◽

Sleep Quality ◽

Nursing Student ◽

Rating Scale ◽

Simple Random Sampling ◽

Anxiety Level ◽

P Value ◽

Cross Sectional ◽

Student Program

Sleep quality is one of basic componen human needs. When the basic human need disturbed it willaffect to activity, work, and health status. Sleep quality can be influenced by many factors such asanxiety level. This Research is aims to find the correlation between anxiety level with sleep quality of Bachelor Nursing Student Program in STIKes Wijaya Husada Bogor. This Research is used Descriptiv Analitik Kualitatif design with approach Cross Sectional. The population studied is Bachelor Nursing student which amounts 290 person. To get sample is using technique Simple Random Sampling with formulas Slovin which amount 168 respondent. The instrumen of this research is Pittsburgh Sleep Quality Index and Hamilton Anxiety Rating Scale, and then data analysis using chi square test. The result from this research show from 168 responden, there are 73 responden (43,5%) have sufficient anxiety level with bad sleep quality amount 51 responden (46,8%). Its obtained P value = 0,038 with value significance is < 0,05. It means Ho is refused and Ha is accepted. And based on result, it can be concluded there is significant correlation between anxiety level with sleep quality of student S 1 Nursing Program in STIKes Wijaya Husada Bogor 2016. And the results obtained by analysis of the value OR 2,492,its mean a person who have a high anxiety level can get a bad sleep quality 2,492 or 2 times greater than a person who have a low anxiety level. There is a correlationbetween anxiety level with sleep quality of Bachelor Nursing Student Program in STIKes Wijaya Husada Bogor It is expected to institutions can make subtlety that can make anxiety level decline so the sleep quality student can be better.

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Restless Leg Syndrome and Sleep Disorders in Patients with Rheumatoid Arthritis and Its Relation with Anemia Parameters

Acta Medica (Hradec Kralove Czech Republic) ◽

10.14712/18059694.2021.24 ◽

2021 ◽

Vol 64 (3) ◽

pp. 137-144

Author(s):

Salih Demir ◽

Adem Kucuk ◽

Mustafa Altas ◽

Erkan Cure

Keyword(s):

Quality Of Life ◽

Rheumatoid Arthritis ◽

Iron Deficiency ◽

Sleep Quality ◽

Sleep Disorders ◽

Rating Scale ◽

Binding Capacity ◽

Anemia Of Chronic Disease ◽

Healthy Control

Objectives: We aimed to investigate the prevalence of restless legs syndrome (RLS) and sleep disorders in patients with rheumatoid arthritis (RA), and the association of iron deficiency with them. Materials and methods: The study included 72 patients with RA (59 females, 13 males), and 50 healthy control subjects (57 females, 15 males). Assessments were made using the International RLS Rating Scale, Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale, Fatigue Severity Scale (FSS), Beck anxiety and depression index and the SF-36 quality of life scores. Results: We found that the frequency of RLS in RA patients was 29.1% and 13.8% in healthy control (p = 0.021). RA patients had 44.4% iron deficiency and 5.5% anemia of chronic disease. We found that 52.3% of patients with iron deficiency had RLS. There was an independent relationship between present of RLS and FSS (Beta [β] = 0.317, p = 0.005) and total iron binding capacity (TIBC) (β = 0.244, p = 0.031). There was an independent relationship between RLS severity score and PSQI (β = 0.264, p = 0.025) and social functionality (β = 0.302, p = 0.009). Conclusion: The prevalence of iron deficiency is high in RA in the developing countries. Analysis obtained in patients with RA is suggestive of an association between iron deficiency and increased frequency of RLS. The presence of RLS in patients with RA negatively affects sleep quality, psychiatric status, and quality of life of patients with RA. TIBC value may be a predictive marker for early detection of RLS in patients with RA.

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