scholarly journals Prevalence of Obesity and Metabolic Syndrome in Adult Population of Selected Regions of the Czech Republic. Relation to Eating Habits and Smoking

2012 ◽  
Vol 113 (3) ◽  
pp. 206-216 ◽  
Author(s):  
Michala Vosátková ◽  
J. Čeřovská ◽  
H. Zamrazilová ◽  
P. Hoskovcová ◽  
M. Dvořáková ◽  
...  

Prevalence of the metabolic syndrome is around 25% in Europe but its occurrence grows in both genders with increasing age and weight. Lifestyle factors may contribute to the risk of developing metabolic syndrome. The objective of this study was to determine the relationship between metabolic syndrome and eating habits as well as length of sleep and smoking. Participants (519 women and 286 men aged 18–65 years) were chosen by random selection and questioned about their eating habits, sleep length and smoking. This information was combined with anthropometric and clinical parameters of metabolic syndrome. The female group was divided into two subgroups depending on climacteric stage (before and after menopause). Metabolic syndrome prevalence does not differ between regions in neither female (29.9%) nor male (32.5%) group. Body mass index ≥25 was detected in 50.4% of all women and 65.7% of men; 23.5% of all women and 21.7% men had body mass index ≥30. In conclusion, metabolic syndrome prevalence was proved to depend on eating habits and family heredity. Positive correlation between the above mentioned factors demonstrated itself in the total sample but not in individual regions. Metabolic syndrome prevalence in Czech adults is comparable with neighbouring countries. No significant interregional differences in metabolic syndrome prevalence within the Czech Republic were detected. In conclusion, relationship between eating habits and metabolic syndrome was confirmed.

2013 ◽  
Vol 98 (12) ◽  
pp. 4899-4907 ◽  
Author(s):  
Kyung Hee Park ◽  
Lesya Zaichenko ◽  
Mary Brinkoetter ◽  
Bindiya Thakkar ◽  
Ayse Sahin-Efe ◽  
...  

Context: Irisin, a recently identified hormone, has been proposed to regulate energy homeostasis and obesity in mice. Whether irisin levels are associated with risk of the metabolic syndrome (MetS), cardiometabolic variables, and cardiovascular disease (CVD) risk in humans remains unknown. Objective: Our objective was to assess the associations between baseline serum irisin levels and MetS, cardiometabolic variables, and CVD risk. Design, Setting, and Subjects: We conducted a comparative cross-sectional evaluation of baseline circulating levels of the novel hormone irisin and the established adipokine adiponectin with MetS, cardiometabolic variables, and CVD risk in a sample of 151 subjects. Results: Baseline irisin levels were significantly higher in subjects with MetS than in subjects without MetS. Irisin was associated negatively with adiponectin (r = −0.4, P < .001) and positively with body mass index (r = 0.22, P = .008), systolic (r = 0.17, P = .04) and diastolic (r = 0.27, P = .001) blood pressure, fasting glucose (r = 0.25, P = .002), triglycerides (r = 0.25, P = .003), and homeostasis model assessment for insulin resistance (r = 0.33, P < .001). After adjustment for potential confounders, including body mass index, subjects in the highest tertile of irisin levels were more likely to have MetS (odds ratio [OR] = 9.44, 95% confidence interval [CI] = 2.66–33.44), elevated fasting blood glucose (OR = 5.80, 95% CI = 1.72–19.60), high triglycerides (OR = 3.89, 95% CI = 1.16–13.03), and low high-density lipoprotein cholesterol (OR = 3.30, 95% CI = 1.18–9.20). Irisin was independently associated with homeostasis model assessment for insulin resistance and general Framingham risk profile in multiple linear regression analyses after adjustment for confounders. Adiponectin demonstrated the expected associations with outcomes. Conclusions: Irisin is associated with increased risk of MetS, cardiometabolic variables, and CVD in humans, indicating either increased secretion by adipose/muscle tissue and/or a compensatory increase of irisin to overcome an underlying irisin resistance in these subjects.


2003 ◽  
pp. 601-608 ◽  
Author(s):  
DE Laaksonen ◽  
L Niskanen ◽  
K Punnonen ◽  
K Nyyssonen ◽  
TP Tuomainen ◽  
...  

OBJECTIVE: Mild hypoandrogenism in men is associated with features of the metabolic syndrome, but the association with the metabolic syndrome itself using an accepted definition has not been described. DESIGN: Men with the metabolic syndrome were identified and testosterone and sex hormone-binding globulin (SHBG) levels were determined in a population-based cohort of 1896 non-diabetic middle-aged Finnish men. RESULTS: Calculated free testosterone and SHBG were 11% and 18% lower (P<0.001) in men with the metabolic syndrome (n=345, World Health Organisation definition). After categorisation by tertiles and adjusting for age and body mass index, total and free testosterone and SHBG were inversely associated with concentrations of insulin, glucose, triglycerides, C-reactive protein (CRP) and CRP-adjusted ferritin and positively associated with high-density lipoprotein cholesterol. Men with free testosterone levels in the lowest third were 2.7 (95% confidence interval (CI) 2.0-3.7) times more likely to have the metabolic syndrome in age-adjusted analyses, and 1.7 (95% CI 1.2-2.4) times more likely even after further adjusting for body mass index. Exclusion of men with cardiovascular disease did not alter the association. The inverse association of SHBG with the metabolic syndrome was somewhat stronger. CONCLUSIONS: Low testosterone and SHBG levels were strongly associated not only with components of the metabolic syndrome, but also with the metabolic syndrome itself, independently of body mass index. Furthermore, sex hormones were associated with inflammation and body iron stores. Even in the absence of late-stage consequences such as diabetes and cardiovascular disease, subtle derangements in sex hormones are present in the metabolic syndrome, and may contribute to its pathogenesis.


2015 ◽  
Vol 3 (3) ◽  
Author(s):  
Trigisa Lasabuda ◽  
Pemsi M. Wowor ◽  
Yanti Mewo

Abstract: Obesity is one manifestation of nutritional problems, which need attention. Obesity is a state of excess body fat in absolute terms and relative. In 2000, the Directorate of Community Nutrition Ministry of Health recorded a total population of Indonesia are categorized as obese estimated 76.7 million (17.5%). Many factors play a role in the occurrence of obesity are largely an interaction between genetic factors and environmental factors, such as physical activity, social, economic, and nutrition. The obesity increases the risk of cardiovascular disease because its related with the metabolic syndrome or insulin resistance syndrome or / hyperinsulinemia, glucose intolerance / diabetes mellitus (DM), dyslipidemia, hypertension and other. This study uses a quantitative research design and cross-sectional approach which takes place from July to August, 2015. The total sample of 20 people were taken to the al-Fatah mosque Malalayang aged 9-21 years. The results of the research showed that respondent with weight less amounted to 8 respondent, respondents with normal weight is 10 respondents and it was the highest, respondent with pre-obesity is only one respondent, while respondent with obesity II also only 1 respondents. Conclusion: The results of this study concluded that the image of the body mass index (BMI) mosque al - Fatah Malalayang respondents with less weight have percentage of 40%, respondents with normal weight have a percentage of 45%, respondents with more weight percentage of 15%, the respondents with pre-obese weight have percentage of 5%, and the respondent with weight obesity II have a percentage of 10%.Keywords: obesity, body mass index (BMI), diabetes mellitus (DM).Abstrak: Obesitas merupakan salah satu manifestasi dari masalah gizi lebih, yang perlu mendapatkan perhatian. Pada tahun 2000, Direktorat Bina Gizi Masyarakat Departemen Kesehatan RI mencatat jumlah penduduk Indonesia yang masuk kategori obesitas diperkirakan 76.7 juta (17.5%) . Banyak faktor yang berperan dalam terjadinya obesitas yang sebagian besar merupakan interaksi antara faktor genetik dengan faktor lingkungan, antara lain aktivitas fisik, sosial ekonomi, dan nutrisi. Keadaan obesitas meningkatkan risiko penyakit-penyakit kardiovaskular karena keterkaitanya dengan sindrom metabolik atau atau sindrom resistensi insulin/hiperinsulinemia, intoleransi glukosa/Diabetes Melitus (DM), dyslipidemia, hipertensi dan lainnya. Penelitian ini menggunakan desain penelitian kuantitatif dan pendekatan cross sectional yang berlangsung dari Juli – Agustus 2015. total sampel berjumlah 20 orang yang diambil pada jamaah Masjid Al- Fatah Malalayang yang berusia 19 – 21 tahun. Berdasarkan hasil penelitian didapatkan bahwa responden yang memiki berat badan kurang berjumlah 8 responden, responden dengan berat badan normal 9 responden dan merupakan yang terbanyak, responden dengan pra obesitas 1 responden, sedangkan responden dengan badan obesitas II 2 responden. Simpulan: Dari hasil penelitian dapat disimpulkan bahwa gambaran Indeks Massa tubuh (IMT) masjid al – fatah malalayang responden dengan berat badan kurang memiliki persentase sebesar 40%, responden dengan berat badan normal memiliki persentase sebesar 45%, responden dengan berat badan lebih memiliki persentase sebesar 15%, responden dengan berat badan pra obesitas memiliki persentase sebesar 5%, Responden dengan berat badan obesitas II memiliki persentase sebesar 10%.Kata kunci: obesitas, indeks massa tubuh (IMT), diabetes mellitus (DM).


Author(s):  
Farid Saad ◽  
Ahmad Haider ◽  
Erik J. Giltay ◽  
Louis J.G. Gooren

AbstractTestosterone administration to hypogonadal men improves the metabolic syndrome. This study analyzed whether age, serum testosterone, body mass index/waist circumference, increment in testosterone values and C-reactive protein (CRP) predicted the outcome of testosterone administration.A total of 110 mainly elderly men, aged between 18 and 83 years (mean±SD=59.6±8.0) with baseline serum testosterone of 5.8–12.1 nmol/L (mean±SD=9.3±1.7) (n>14.0 nmol/L), received parenteral testosterone undecanoate whereupon serum testosterone normalized between 3 and 24 months.(i) The lower the baseline testosterone, the stronger the decreases in waist size and triglycerides. (ii) The greater the increment in serum testosterone, the stronger the decreases in low-density lipoprotein (LDL) cholesterol, triglycerides and glucose. (iii) Older age was associated with stronger beneficial effects on waist size, glucose and all lipids, but a small negative effect on high-density lipoprotein cholesterol. (iv) Obese men and men with the largest waist circumference showed the strongest declines over 2 years in weight, waist circumference and body mass index (BMI), and also in total cholesterol, triglycerides and glucose. Baseline BMI predicted a stronger decline in LDL cholesterol, but a smaller decline in CRP levels. (v) Higher baseline CRP predicted larger declines in levels of triglycerides, glucose and CRP. (vi) In the multivariate model, age, BMI and CRP were independent predictors of the strongest benefit of testosterone treatment on the metabolic syndrome.Older men, particularly when obese with chronic low-grade inflammation benefited most of normalizing their testosterone levels, preferably if they reached mid-normal reference values.


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