Does Helicobacter pylori Infection Contribute to the Pathogenesis of Portal Hypertensive Gastropathy? A Cross-Sectional Observational Study at a Tertiary Care Center

2018 ◽  
Vol 3 (1) ◽  
pp. 16-19
Author(s):  
Ravi K ◽  
Jacob Joseph ◽  
David Mathew Thomas
Author(s):  
Subrata Kumar Das ◽  
Saptadipa Das

<p class="abstract"><strong>Background:</strong> The aim was to evaluate the parameters of metabolic syndrome (MS) in patients of alopecia areata and to investigate the possibility of an existing relationship between MS and alopecia areata (AA).</p><p class="abstract"><strong>Methods:</strong> This cross-sectional observational study included 50 patients with AA who attended OPD of department of dermatology at a tertiary care center during a period of 1 year. Clinical and laboratory parameters were noted in each patient.<strong></strong></p><p class="abstract"><strong>Results:</strong> This study included 50 patients with AA (33 males and 17 females). In the present study maximum number of patients belonged to the age group 20-30 years with 23 patients, followed by 30-40 years with 17  patients. Most of the study subjects, 17 were college students and number of employees were 15. Out of 50 patients 44  had patch(es) and 2 patient had alopecia totalis. In this study out of 50 patients, 38 had mild AA, 7 had AA and 5 patients had severe AA. No significant derangement of clinical and laboratory parameters of MS observed in patients of AA.</p><p class="abstract"><strong>Conclusions:</strong> In the present study we did not observe any significant derangement of clinical and laboratory parameters of  MS  in patients of alopecia areata.</p>


2019 ◽  
Vol 6 (9) ◽  
pp. 474-480
Author(s):  
Dr. Chandra Mohan Chekkali ◽  
◽  
Dr. Greeshma Reddy Kankanala ◽  
Dr. Rakesh Kotha ◽  
Dr. Himabindu Singh ◽  
...  

2017 ◽  
Vol 4 (5) ◽  
pp. 1644 ◽  
Author(s):  
Ramesh Choudhary ◽  
Sunil Gothwal ◽  
Swati Nayan ◽  
B. S. Meena

Background: The development in science and technology has helped us to overcome the superstitions associated with pregnancy to some extent. Objective of present study was to record information about common ritualistic myths during pregnancy and after baby birth.Methods: It was a cross sectional observational study conducted in a tertiary care center. Information was collected from 200 admitted women who delivered in last 3 days with direct questions to mother.Results: Total 180 (90%) women were following the ritualistic myths. Mean age and mean parity was 30.1 years and 2.8 respectively. Sixty five percent women were belonging from rural background. Religion distribution was as follows 144 Hindu, 40 Muslim and 16 were others. Prevalence of the myths was 136 (94.4%), 32 (80%), 12 (75%) in Hindu, Muslim and other religions respectively. An inverse relation was observed between education level and acceptance of myth.Conclusions: Ritualistic myths during pregnancy and after birth were more common with low literacy, rural background and in Hindus. 


Author(s):  
R. I. Khlynova ◽  
O. M. Khromtsova ◽  
R. B. Berdnikov ◽  
I. B. Khlynov

The aim is to study the effect of Helicobacter pylori infection on risk of developing gastroesophageal reflux disease. Materials and methods - cross-sectional observational study of 1007 patients with dyspepsia syndrome who underwent videoesophagogastroduodenoscopy with biopsy and histological examination of biopsy specimens of the gastric mucosa by OLGA-system. The age, gender, overweight, cigarette smoking, presence of Helicobacter pylori infection and gastritis stage were assessed. Results - the study showed a significant decrease in the incidence of gastroesophageal reflux disease in patients with positive H. Pylori status by 4% (RR 0,68; 95% CI, 0.49-0.94, p=0,041). The risk of developing gastroesophageal reflux disease significantly higher in overweight (RR 2,62; 95% CI 2,0-3,56; р<0,001) men (RR 1,76; 95% CI 1,33-2,32; р=0,0046) who smoked cigarettes (RR 3,23; 95% CI 2,45-4,24; р<0,001) and was not associated with the patient’s age and the stage of gastritis (р>0,05). Conclusion - a significant reduction in the frequency and risk of developing gastroesophageal reflux disease in patients with Helicobacter pylori infection is demonstrated.


2021 ◽  
Vol 12 (2) ◽  
pp. 120-129
Author(s):  
Romita Bachaspatimayum ◽  
Zamzachin Guite ◽  
Thangjam Bijayanti Devi

Background: Genital ulcers are defined as breaches in the continuity of the genital mucosa and/or skin. Sexually transmitted infections (STIs) that cause genital ulcer disease (GUD) are syphilis, chancroid, donovanosis, lymphogranuloma venereum (LGV), and herpes genitalis. This study aimed to investigate the clinical and laboratory profiles of STI-related genital ulcers. Materials and Methods: A cross-sectional two-year study was conducted on patients attending the Outpatient Department of Dermatology, Venereology and Leprosy in a tertiary care center in northeastern India. Selected were 95 patients who presented themselves with STI-related genital ulcers. Detailed history taking and examination were conducted with basic tests to assist the diagnosis. Results: The male-to-female ratio was 3.32:1, and the most common site was the glans and prepuce in males (28.77%) and the labia majora and minora in females (36.36%). 96.84% of patients had superficial ulcers. The KOH mount was positive in 26 patients. The Tzanck smear was positive in 31 patients. RPR was positive in four. HIV was positive in eleven. Herpes genitalis (96.84%) was the most common GUD. Mixed STIs were attested in 41.05% of patients. Conclusion: GUD can take various forms of presentation. The available laboratory tests should be utilized. The possibility of mixed infections should always be kept in mind.


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