scholarly journals I verbi di servizio (modali, aspettuali e causativi) e i verbi supporto nelle grammatiche descrittive d’italiano dal 1953 al 2005

2020 ◽  
Vol 47 (2) ◽  
pp. 21-32
Author(s):  
Anna Godzich
Keyword(s):  
Integrated Approach ◽  
Complex Predicates ◽  
Form Complex ◽  
Light Verbs ◽  
Word Classes ◽  
Causative Verbs

The paper deals with Italian helping verbs (modal, aspectual, causative verbs) and light verbs which form complex predicates and with the rules that guide its use in Italian descriptive grammars published in Italy between 1953 and 2005. The author shows that those forms in both – traditional and contemporary Italian descriptive grammars are treated at the level of word classes whereas it could be more appropriate to discuss them as clause elements as they form complex predicates. In our opinion this way of describing such verbs is due to the tradition in Italy to focus on a form and not on function of an element. What is more, Italian grammarians tend to omit in Italian descriptive grammars noun predicationand the role of semantic predicate (n pred.). The goal of the paper is to present the advantages of an integrated approach to helping verbs (modal, aspectual, causative verbs) and light verbs in modern Italian. The author emphasizes its importance for contemporary Italian FL syntax teaching.

scholarly journals Complex predicates and light verb constructions in Modern Irish

2014 ◽  
Vol 27 (1) ◽  
pp. 140-167 ◽  
Author(s):  
Brian Nolan
Keyword(s):  
Argument Structure ◽  
Complex Predicates ◽  
Form Complex ◽  
Light Verbs ◽  
Role And Reference Grammar ◽  
Light Verb Constructions ◽  
Light Verb ◽  
Verb Constructions ◽  
The Matrix ◽  
Matrix Verb

This paper characterises complex predicates and light verb constructions in Modern Irish. Light verbs are attested in many of the world’s languages (Alsina, Bresnan & Sells, 2001; Butt, 1995, 2003). Cross linguistically, there appears to be a common class of verbs involved in these constructions and generally there is agreement that light verbs contribute to the formation of complex predicates. Light verbs seem have a non-light or ‘heavy’ verb counterpart. In this paper we discuss the light verb constructions (LVC) as found in modern Irish and how they form complex predicates. We claim that the light verb (LV) encodes the event process initiation (or cause) and the matrix verb indicates the bounded component or result. In light verb constructions, the matrix verb appears in Modern Irish syntax as a verbal-noun form. The function of light verbs in these constructions is to modulate the event and sub-event semantics. We distinguish between auxiliary verbs constructions (AVC) and those constructions involving complex predicated and light verbs (Aikhenvald & Dixon, 2006; Anderson, 2006). We provide evidence based on an analysis of Irish data that shows how aspect and argument structure considerations are resolved for the complex predicate within the light verb construction via the linking system between semantics and syntax. We motivate a functional account, based on Role and Reference Grammar (Nolan, 2012; Nolan & Diedrichsen, 2013; Van Valin, 2005; Van Valin & LaPolla, 1997), that appeals to the analysis of complex predicates within a consideration of the layered structure of the clause.

scholarly journals Interplay Between SOX9, Wnt/β-Catenin and Androgen Receptor Signaling in Castration-Resistant Prostate Cancer

2019 ◽  
Vol 20 (9) ◽  
pp. 2066 ◽  
Author(s):  
Namrata Khurana ◽  
Suresh C. Sikka
Keyword(s):  
Prostate Cancer ◽  
Androgen Receptor ◽  
Signaling Pathways ◽  
Critical Role ◽  
Castration Resistant Prostate Cancer ◽  
Form Complex ◽  
Androgen Receptor Signaling ◽  
Castration Resistant ◽  
Signaling Axis

Androgen receptor (AR) signaling plays a key role not only in the initiation of prostate cancer (PCa) but also in its transition to aggressive and invasive castration-resistant prostate cancer (CRPC). However, the crosstalk of AR with other signaling pathways contributes significantly to the emergence and growth of CRPC. Wnt/β-catenin signaling facilitates ductal morphogenesis in fetal prostate and its anomalous expression has been linked with PCa. β-catenin has also been reported to form complex with AR and thus augment AR signaling in PCa. The transcription factor SOX9 has been shown to be the driving force of aggressive and invasive PCa cells and regulate AR expression in PCa cells. Furthermore, SOX9 has also been shown to propel PCa by the reactivation of Wnt/β-catenin signaling. In this review, we discuss the critical role of SOX9/AR/Wnt/β-catenin signaling axis in the development and progression of CRPC. The phytochemicals like sulforaphane and curcumin that can concurrently target SOX9, AR and Wnt/β-catenin signaling pathways in PCa may thus be beneficial in the chemoprevention of PCa.

scholarly journals The Role of Faults in Groundwater Circulation before and after Seismic Events: Insights from Tracers, Water Isotopes and Geochemistry

Water ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 1499
Author(s):  
Davide Fronzi ◽  
Francesco Mirabella ◽  
Carlo Cardellini ◽  
Stefano Caliro ◽  
Stefano Palpacelli ◽  
...  
Keyword(s):  
Preferential Flow ◽  
Central Italy ◽  
Tracer Tests ◽  
Integrated Approach ◽  
Fault System ◽  
Tectonic Structures ◽  
Fault Systems ◽  
Isotopic Analyses ◽  
Before And After

The interaction between fluids and tectonic structures such as fault systems is a much-discussed issue. Many scientific works are aimed at understanding what the role of fault systems in the displacement of deep fluids is, by investigating the interaction between the upper mantle, the lower crustal portion and the upraising of gasses carried by liquids. Many other scientific works try to explore the interaction between the recharge processes, i.e., precipitation, and the fault zones, aiming to recognize the function of the abovementioned structures and their capability to direct groundwater flow towards preferential drainage areas. Understanding the role of faults in the recharge processes of punctual and linear springs, meant as gaining streams, is a key point in hydrogeology, as it is known that faults can act either as flow barriers or as preferential flow paths. In this work an investigation of a fault system located in the Nera River catchment (Italy), based on geo-structural investigations, tracer tests, geochemical and isotopic recharge modelling, allows to identify the role of the normal fault system before and after the 2016–2017 central Italy seismic sequence (Mmax = 6.5). The outcome was achieved by an integrated approach consisting of a structural geology field work, combined with GIS-based analysis, and of a hydrogeological investigation based on artificial tracer tests and geochemical and isotopic analyses.

Individual differences in political aggression: The role of social integration, perceived grievances and low self-control

2018 ◽  
Vol 17 (5) ◽  
pp. 603-627 ◽  
Author(s):  
Lieven J.R. Pauwels ◽  
Vanja Ljujic ◽  
Ann De Buck
Keyword(s):  
Individual Differences ◽  
Social Integration ◽  
Structural Equation ◽  
Integrated Approach ◽  
Self Control ◽  
Content Support ◽  
Log Linear ◽  
Low Self Control ◽  
And Function

Several models have been suggested for studying (self-reported) aggression. Less frequently, these theories are empirically applied to explain individual differences in political aggression. The present study examines the role of distal, intermediate and proximate mechanisms in a net-sample of 6020 young adults. Using log-linear structural equation modelling, the independent effects of cumulative social integration, perceived personal and group injustices and low self-control are assessed. It is assumed that these factors contribute to the ‘crystallization of discontent’ by fostering religious authoritarianism, political powerlessness, support for extremist beliefs and online exposure to extremist content. Support for extremist content and online exposure to extremist content are strong predictors, and function as different routes towards political aggression. The results support an integrated approach towards the study of political aggression. Implications for future studies are discussed.

Role of complementary shape in protein dimerization

Soft Matter ◽  
2021 ◽  
Author(s):  
Fengyi Gao ◽  
Jens Glaser ◽  
Sharon C Glotzer
Keyword(s):  
Colloidal Nanoparticles ◽  
Protein Dimerization ◽  
Form Complex ◽  
Biomolecular Complexes

Shape guides colloidal nanoparticles to form complex assemblies, but its role in defining interfaces in biomolecular complexes is less clear. In this work, we isolate the role of shape in...

ROLE OF VITAMIN D IN COVID VACCINE EFFICACY IN ELDERLY IN INDIAN POPULATION

2021 ◽  
pp. 55-56
Author(s):  
Gujjarlapudi Deepika ◽  
Duvuru Nageshwar Reddy
Keyword(s):  
Older Adults ◽  
Vitamin D ◽  
Immune Response ◽  
Indian Population ◽  
Integrated Approach ◽  
Inclusion Criteria ◽  
Vitamin D Levels ◽  
History Of ◽  
Study Inclusion

Background: Aim of this study is to summarise the role of Vitamin D in supporting the immune system,in covid vaccinated recipients. This is a observational study done between April 2021 t Methods: o June 2021 in Indian population. We compared anti-SARS-CoV-2 spike RBDIgG antibody & antispike antibodies following vaccination of non-hospitalized participants along with vitamin D levels in recipients above 60 years. They were tested after vaccination after two doses between 15-45 days. Before study inclusion criteria is, we have checked whether they were as seropositive or seronegative based on nucleocapsid total antibody results. of 310 Results vaccine recipients, 46 reported a prior COVID-19 diagnosis and we have excluded them from the study of the 264 with no history of Covid-19, 70 were vitamin d decient (50M;20 F) & 194 (130 M:64 F) were vitamin d Sufcient. Responses were evaluated after two doses on an average post-vaccine RBD IgG concentration and Spike antibodies were each signicantly higher among the Vit d sufcient recipients compared to the vitamin D Decient recipients. An integrated approach is required to bett Conclusions: er understand aging and how vaccines work in elderly which will help in improving the immune response in older adults after vaccination.

The antiviral lectin cyanovirin-N: probing multivalency and glycan recognition through experimental and computational approaches

2013 ◽  
Vol 41 (5) ◽  
pp. 1170-1176 ◽  
Author(s):  
Brian W. Woodrum ◽  
Jason D. Maxwell ◽  
Ashini Bolia ◽  
S. Banu Ozkan ◽  
Giovanna Ghirlanda
Keyword(s):  
Viral Entry ◽  
High Specificity ◽  
Integrated Approach ◽  
Protein Gp120 ◽  
Computational Work ◽  
Gp120 Glycoprotein ◽  
Anti Hiv Agents ◽  
Anti Hiv ◽  
Envelope Protein Gp120

CVN (cyanovirin-N), a small lectin isolated from cyanobacteria, exemplifies a novel class of anti-HIV agents that act by binding to the highly glycosylated envelope protein gp120 (glycoprotein 120), resulting in inhibition of the crucial viral entry step. In the present review, we summarize recent work in our laboratory and others towards determining the crucial role of multivalency in the antiviral activity, and we discuss features that contribute to the high specificity and affinity for the glycan ligand observed in CVN. An integrated approach that encompasses structural determination, mutagenesis analysis and computational work holds particular promise to clarify aspects of the interactions between CVN and glycans.

Urban drainage redefined: from stormwater removal to integrated management

2001 ◽  
Vol 43 (5) ◽  
pp. 61-68 ◽  
Author(s):  
B. Chocat ◽  
P. Krebs ◽  
J. Marsalek ◽  
W. Rauch ◽  
W. Schilling
Keyword(s):  
New Technologies ◽  
Integrated Management ◽  
Integrated Approach ◽  
Optimal Operation ◽  
Urban Drainage ◽  
Wastewater Systems ◽  
Adaptive Water Management ◽  
Receiving Waters ◽  
The Many

Even though urban drainage has been practised for more than 5000 years, many challenges arising from growing demands on drainage still remain with respect to runoff quantity and quality; landscape aesthetics, ecology and beneficial uses; and operation of existing urban wastewater systems. Further advances can be achieved by adopting an integrated approach, optimal operation of the existing infrastructure, advanced pollution and runoff source controls, improved resilience of receiving waters, and adaptive water management. The specific research needs include new technologies and strategies for stormwater management, advanced treatment of urban wet-weather effluents, and tools for analysis and operation of drainage systems. High diversity of demands on, and region/site specific conditions of, urban drainage shapes the role of urban drainage experts – as mediators among the many stakeholders and fields involved.

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