scholarly journals Impact of acute exercise on peripheral blood mononuclear cells nutrient sensing and mitochondrial oxidative capacity in healthy young adults

2021 ◽  
Vol 9 (23) ◽  
Author(s):  
Bailey Theall ◽  
James Stampley ◽  
Eunhan Cho ◽  
Joshua Granger ◽  
Neil M. Johannsen ◽  
...  
Keyword(s):  
Young Adults ◽  
Peripheral Blood Mononuclear Cells ◽  
Peripheral Blood ◽  
Acute Exercise ◽  
Mononuclear Cells ◽  
Oxidative Capacity ◽  
Nutrient Sensing ◽  
Peripheral Blood Mononuclear ◽  
Blood Mononuclear Cells ◽  
Mitochondrial Oxidative Capacity

scholarly journals Peripheral Blood Mononuclear Cells and Platelets Mitochondrial Dysfunction, Oxidative Stress, and Circulating mtDNA in Cardiovascular Diseases

2020 ◽  
Vol 9 (2) ◽  
pp. 311 ◽  
Author(s):  
Abrar Alfatni ◽  
Marianne Riou ◽  
Anne-Laure Charles ◽  
Alain Meyer ◽  
Cindy Barnig ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cardiovascular Diseases ◽  
Mitochondrial Dysfunction ◽  
Peripheral Blood Mononuclear Cells ◽  
Peripheral Blood ◽  
Mononuclear Cells ◽  
Oxidative Capacity ◽  
Ros Production ◽  
Peripheral Blood Mononuclear ◽  
Blood Mononuclear Cells

Cardiovascular diseases (CVDs) are devastating disorders and the leading cause of mortality worldwide. The pathophysiology of cardiovascular diseases is complex and multifactorial and, in the past years, mitochondrial dysfunction and excessive production of reactive oxygen species (ROS) have gained growing attention. Indeed, CVDs can be considered as a systemic alteration, and understanding the eventual implication of circulating blood cells peripheral blood mononuclear cells (PBMCs) and or platelets, and particularly their mitochondrial function, ROS production, and mitochondrial DNA (mtDNA) releases in patients with cardiac impairments, appears worthwhile. Interestingly, reports consistently demonstrate a reduced mitochondrial respiratory chain oxidative capacity related to the degree of CVD severity and to an increased ROS production by PBMCs. Further, circulating mtDNA level was generally modified in such patients. These data are critical steps in term of cardiac disease comprehension and further studies are warranted to challenge the possible adjunct of PBMCs’ and platelets’ mitochondrial dysfunction, oxidative stress, and circulating mtDNA as biomarkers of CVD diagnosis and prognosis. This new approach might also allow further interesting therapeutic developments.

Regulation of autophagy following ex vivo heating in peripheral blood mononuclear cells from young adults

2020 ◽  
Vol 91 ◽  
pp. 102643 ◽  
Author(s):  
James J. McCormick ◽  
Kelli E. King ◽  
Melissa D. Côté ◽  
Morgan K. McManus ◽  
Serena M. Topshee ◽  
...  
Keyword(s):  
Young Adults ◽  
Peripheral Blood Mononuclear Cells ◽  
Peripheral Blood ◽  
Mononuclear Cells ◽  
Ex Vivo ◽  
Peripheral Blood Mononuclear ◽  
Blood Mononuclear Cells

scholarly journals Sex Differences in Heat Shock Protein 72 Expression in Peripheral Blood Mononuclear Cells to Acute Exercise in the Heat

2012 ◽  
Vol 11 (4) ◽  
Author(s):  
Trevor L. Gillum ◽  
Matthew Kuennen ◽  
Cheryl Gourley ◽  
Karol Dokladny ◽  
Suzanne Schneider ◽  
...  
Keyword(s):  
Sex Differences ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Peripheral Blood Mononuclear Cells ◽  
Peripheral Blood ◽  
Acute Exercise ◽  
Mononuclear Cells ◽  
Heat Shock Protein 72 ◽  
Peripheral Blood Mononuclear ◽  
Blood Mononuclear Cells

scholarly journals The effect of acute exercise on GLUT4 levels in peripheral blood mononuclear cells of sled dogs

2015 ◽  
Vol 2 ◽  
pp. 45-49 ◽  
Author(s):  
Theresia M. Schnurr ◽  
Arleigh J. Reynolds ◽  
Alyssa M. Komac ◽  
Lawrence K. Duffy ◽  
Kriya L. Dunlap
Keyword(s):  
Peripheral Blood Mononuclear Cells ◽  
Peripheral Blood ◽  
Acute Exercise ◽  
Mononuclear Cells ◽  
Peripheral Blood Mononuclear ◽  
Sled Dogs ◽  
Blood Mononuclear Cells
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