scholarly journals LSD: a new treatment emerging from the past

2015 ◽  
Vol 187 (14) ◽  
pp. 1079-1080 ◽  
Author(s):  
Erika Dyck
Keyword(s):  
The Past ◽  
New Treatment

Non-viral aspects

2018 ◽  
Vol 1 (2) ◽  
pp. 37-39
Author(s):  
Roongruedee Chaiteerakij
Keyword(s):  
Autoimmune Hepatitis ◽  
Liver Diseases ◽  
Sclerosing Cholangitis ◽  
Promising Result ◽  
Primary Biliary Cholangitis ◽  
Second Line Therapy ◽  
Thai Population ◽  
The Past ◽  
Line Therapy ◽  
New Treatment

Autoimmuneliver diseases, particularly autoimmune hepatitis and primary biliary cholangitis,are not uncommon among the Thai population. This article summarizes main findings of studies of autoimmune liver diseases published during the past year, which included natural history and long-termoutcomes of primary biliary cholangitis treatment, a promising result of the new treatment for primary sclerosing cholangitis and outcomes of a second-line therapy of autoimmune hepatitis.

scholarly journals Creating Price Indexes for Measuring Productivity in Mental Health Care

2001 ◽  
Vol 4 (1) ◽  
Author(s):  
Susan H. Busch ◽  
Ernst R. Berndt ◽  
Richard G. Frank
Keyword(s):  
Mental Health ◽  
Health Care ◽  
Major Depression ◽  
Price Index ◽  
Time Varying ◽  
Measurement Issues ◽  
The Past ◽  
Price Indexes ◽  
Treatment Technologies ◽  
New Treatment

Economists have long suggested that to be reliable, a preferred medical care price index should employ time-varying weights to measure outcomes-adjusted changes in the price of treating an episode of illness. In this article, we report on several years of research developing alternative indexes for the treatment of the acute phase of major depression, for the period 1991–1996. The introduction of new treatment technologies in the past two decades suggests well-known measurement issues may be prominent in constructing such a price index.We report on the results of four successively re

scholarly journals Emergency management of the paediatric patient with convulsive status epilepticus

2021 ◽  
Vol 26 (1) ◽  
pp. 50-57
Author(s):  
Kyle C McKenzie ◽  
Cecil D Hahn ◽  
Jeremy N Friedman
Keyword(s):  
Clinical Practice ◽  
Status Epilepticus ◽  
Emergency Management ◽  
Treatment Algorithm ◽  
Position Statement ◽  
Convulsive Status Epilepticus ◽  
Pharmacological Management ◽  
The Past ◽  
New Treatment ◽  
New Evidence

Abstract This guideline addresses the emergency management of convulsive status epilepticus (CSE) in children and infants older than 1 month of age. It replaces a previous position statement from 2011, and includes a new treatment algorithm and table of recommended medications based on new evidence and reflecting the evolution of clinical practice over the past several years. This statement emphasizes the importance of timely pharmacological management of CSE, and includes some guidance for diagnostic approach and supportive care.

scholarly journals A New Classification for Hemorrhoidal Disease: The Creation of the “BPRST” Staging and Its Application in Clinical Practice

2020 ◽  
Vol 36 (4) ◽  
pp. 249-255 ◽  
Author(s):  
Carlos Walter Sobrado Júnior ◽  
Carlos de Almeida Obregon ◽  
Afonso Henrique da Silva e Sousa Júnior ◽  
Lucas Faraco Sobrado ◽  
Sérgio Carlos Nahas ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Strong Association ◽  
Management Strategies ◽  
Hemorrhoidal Disease ◽  
New Classification ◽  
The Past ◽  
Internal Hemorrhoids ◽  
New Treatment ◽  
Treatment Alternatives

Purpose: Present an updated classification for symptomatic hemorrhoids, which not only guides the treatment of internal hemorrhoids but also the treatment of external components. In addition, this new classification includes new treatment alternatives created over the last few years.Methods: Throughout the past 7 years, the authors developed a method to classify patients with symptomatic hemorrhoids. This study, besides presenting this classification proposal, also retrospectively analyzed 149 consecutive patients treated between March 2011 and November 2013 and aimed to evaluate the association between the management adopted with Goligher classification and our proposed BPRST classification.Results: Both classifications had a statistically significant association with the adopted management strategies. However, the BPRST classification tended to have fewer management discrepancies when each stage of disease was individually analyzed.Conclusion: Although there is much disagreement about how the classification of hemorrhoidal disease should be updated, it is accepted that some kind of revision is needed. The BPRST method showed a strong association with the management that should be adopted for each stage of the disease. Further studies are needed for its validation, but the current results are encouraging.

scholarly journals Biological psychiatry: time for new paradigms

2013 ◽  
Vol 202 (3) ◽  
pp. 166-167 ◽  
Author(s):  
David Linden
Keyword(s):  
Biological Treatment ◽  
Biological Psychiatry ◽  
Psychiatric Diseases ◽  
Treatment Principles ◽  
Treatment Targets ◽  
The Past ◽  
Slow Progress ◽  
New Treatment

SummaryBiological psychiatry has not yet produced clinically viable biomarkers for any of the major psychiatric diseases, and the past 25 years have not brought any fundamentally new biological treatment principles. I discuss reasons for this slow progress and suggest avenues for the development of biomarkers and the discovery of new treatment targets.

Hemostatic and thrombotic disorders in the pediatric patient

Blood ◽  
2021 ◽  
Author(s):  
Sarah H. O'Brien ◽  
Ayesha Zia
Keyword(s):  
Venous Thromboembolism ◽  
Prediction Models ◽  
Oral Anticoagulants ◽  
Direct Oral Anticoagulants ◽  
Hospital Setting ◽  
Von Willebrand Disease ◽  
Assessment Tools ◽  
Excessive Bleeding ◽  
The Past ◽  
New Treatment

This review focuses on significant advances in the field of pediatric hemostasis and thrombosis, with a focus on published studies within the past decade. The evaluation and management of patients with excessive bleeding remain a cornerstone of consultative hematology. We will describe the development of validated bleeding assessment tools relevant to pediatric practice, laboratory advances in the evaluation of von Willebrand Disease, and a shift in clinical practice regarding the interpretation of normal coagulation studies in patients with significant bleeding phenotypes. There have also been critical advances in the management of hemostatic disorders. This review highlights new treatment paradigms in hemophilia and the rise of multidisciplinary medical homes for women living with bleeding disorders. Given the continued increase in the incidence of thrombosis, particularly in the hospital setting, a full call to arms against pediatric venous thromboembolism is now essential. This review will describe recently completed clinical trials of direct oral anticoagulants in children and adolescents and ongoing work to elucidate the appropriate duration of therapy for children with provoked thrombosis. Recent work regarding the prevention of pediatric venous thromboembolism is highlighted, including studies of thromboprophylaxis and the development of risk-prediction models for hospital-acquired thrombosis. Finally, we review advances in our understanding of post-thrombotic sequelae and the need for continued refinement of our evaluation tools. Despite the significant advances in pediatric hemostasis and thrombosis over the past decade, many unanswered questions remain for the next generation of investigators.

scholarly journals Vestibular implants studied in animal models: clinical and scientific implications

2016 ◽  
Vol 116 (6) ◽  
pp. 2777-2788 ◽  
Author(s):  
Richard F. Lewis
Keyword(s):  
Animal Models ◽  
Vestibular System ◽  
Animal Studies ◽  
Vestibular Function ◽  
Clinical Problem ◽  
Head Motion ◽  
The Past ◽  
New Treatment ◽  
Vestibular Damage ◽  
The Brain

Damage to the peripheral vestibular system can result in debilitating postural, perceptual, and visual symptoms. A potential new treatment for this clinical problem is to replace some aspects of peripheral vestibular function with an implant that senses head motion and provides this information to the brain by stimulating branches of the vestibular nerve. In this review I consider animal studies performed at our institution over the past 15 years, which have helped elucidate how the brain processes information provided by a vestibular (semicircular canal) implant and how this information could be used to improve the problems experienced by patients with peripheral vestibular damage.

Mandibular Fracture Reduction with Eccentric Dynamic Compression Plate: New Treatment for an Old Problem

1981 ◽  
Vol 89 (4) ◽  
pp. 569-574 ◽  
Author(s):  
Paul A. Levine ◽  
Richard L. Goode
Keyword(s):  
Dynamic Compression ◽  
The United States ◽  
Mandibular Fracture ◽  
Soft Tissue Infections ◽  
Dynamic Compression Plate ◽  
The Past ◽  
Compression Plate ◽  
Bony Healing ◽  
New Treatment ◽  
Edentulous Patients

We describe a technique and theory of application of the Eccentric Dynamic Compression Plate (EDCP) and the Dynamic Compression Plate (DCP) for mandibular fracture fixation, developed by Speissl in Switzerland, and our experience with the application of 15 plates in ten edentulous or nearly edentulous patients over the past 18 months. While we have had soft tissue infections in 4 of 15 fracture sites, our results reveal satisfactory bony healing in 14 of 15 fracture sites. We, therefore, believe that while this technique is still in the infant stages of clinical application in the United States, it has the potential to revolutionize the thinking and practice of mandibular fracture therapy.

Client Information Handout Reprinted from Pet Focus, with Permission

1991 ◽  
Vol 8 (2) ◽  
pp. 26-30 ◽  
Author(s):  
Kenneth F. Lyon
Keyword(s):  
Health Care ◽  
Dental Care ◽  
The Past ◽  
Treatment Techniques ◽  
Recent Developments ◽  
New Treatment

Today, it is recognized that our pets have dental problems that went unrecognized and untreated in the past. Recent developments in the field of veterinary dentistry, increased owner awareness, and new treatment techniques make dental care an indispensable part of pet health care. Routine preventative procedures such as brushing the teeth should be a regular aspect of the care we extend to our pets. J. Vet. Dent., 1991; 8(2): 26–30.

Head Injuries: A New Treatment for the Post-Concussive Syndrome

1947 ◽  
Vol 93 (391) ◽  
pp. 303-317 ◽  
Author(s):  
Helen S. E. Murray ◽  
H. Halstead
Keyword(s):  
Head Trauma ◽  
Head Injuries ◽  
Personality Change ◽  
The Past ◽  
Traumatic Neurosis ◽  
Symptom Complex ◽  
Post Traumatic ◽  
New Treatment ◽  
Persistent Disability ◽  
The Brain

Gunshot and shrapnel wounds of the head during the war have produced various disabilities not commonly seen in the injuries of peace-time.The symptom complex which usually appears subsequent to head trauma has become very familiar during the past few years. The resemblance from case to case of certain sequelae to head injuries has been grouped together in syndromes, variously labelled post-concussive syndrome, post-traumatic personality change, post-traumatic neurosis and post-contusional state, all indicating an oft-recurring persistent disability following concussion of the brain.

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