Detection of Melanoma Skin Disease by Extracting High Level Features for Skin Lesions

2018 ◽  
Vol 11 (3/4) ◽  
pp. 1
Author(s):  
VIKASH YADAV ◽  
VANDANA DIXIT KAUSHIK
Keyword(s):  
Skin Disease ◽  
Skin Lesions ◽  
High Level ◽  
Melanoma Skin

Diagnosis of Skin Melanoma Cancer using Image Based Computer-Aided Diagnosis System from Dermoscopic Images

2021 ◽  
Vol 9 (7) ◽  
pp. 1-5
Author(s):  
Jidnyasa Zambare ◽  
Priya Patil ◽  
Neha Chavan
Keyword(s):  
Skin Test ◽  
Skin Disease ◽  
Air Bubbles ◽  
Skin Melanoma ◽  
Malignant Growth ◽  
Skin Injury ◽  
Melanoma Cancer ◽  
Computer Aided ◽  
Aided Diagnosis ◽  
Melanoma Skin

Skin malignant growth is the most widely recognized, everything being equal. Between 40 to 50 percent of all disease cases analyzed each year are skin malignant growth. Melanomas represent just four percent of all skin malignant growth cases yet are undeniably more perilous. Of all skin disease-related passing’s, 79 percent are from melanoma. Skin disease can be relieved if distinguished early. To appropriately distinguish melanoma, there is a need for a skin test. This is an obtrusive method and is the reason there is a requirement of a conclusion framework that can annihilate the skin test strategy emerges. We proposed to build up a Computer-Aided System that is equipped for ordering a skin injury as threatening or favorable by utilizing the ABCD rule which represents Asymmetry, Border, Color, Diameter of the skin sore. Further, the preprocessed pictures are portioned and commotions are taken out from the Dermoscopic pictures for instance hair and air bubbles. Also, finally, by utilizing a classifier, the proposed system identifies the pictures as favorable or harmful.

The protean phenotype of MSH6 pathogenic variants (PV) in Lynch syndrome (LS) patients (pts).

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. 10537-10537
Author(s):  
Michelle J McSweeny ◽  
Susan Montgomery ◽  
Kristen Danielle Whitaker ◽  
Mary Beryl Daly ◽  
Michael J. Hall
Keyword(s):  
Skin Disease ◽  
Early Onset ◽  
Skin Lesions ◽  
Published Data ◽  
Pedigree Data ◽  
Skin Manifestations ◽  
Pathogenic Variants ◽  
Ca 50 ◽  
Uncertain Variant ◽  
Histologic Types

10537 Background: LS is among the most common hereditary cancer (CA) syndromes. PVs in MSH6 are 2-4 fold more common in the population (1/758) than those in MLH1 (1/1946) or MSH2 (1/2841), and are increasingly regarded as lower penetrance for CRC due to published data supporting later mean age of CRC onset and lower CRC risk. Unlike for MLH1/MSH2, NCCN 2020 CA risk estimates recognize only endometrial CA (EC) and CRC risks in MSH6+ carriers as clearly above SEER population estimates. Further, risks of other LS manifestations such as skin disease/Muir-Torre, ovarian CA (OC), and possible rare tumors in LS like sarcoma, have been minimally characterized in MSH6+ carriers. Methods: Pedigree data for 44 MSH6+ index (first-evaluated family member by our program) pts consecutively ascertained since 2009 at Fox Chase (FCCC) were reviewed. 1 pt w/a rare MSH6 uncertain variant w/personal history (PHx) of MSH6-expression deficient EC (age 50) and MSH6-deficient sebaceous skin CA (age 50) and a strong family history (FHx) c/w LS is also included here. 34% (15/44) index pts were referred to FCCC for cascade testing due to a known MSH6 PV in the family. Of the remaining 29 index pts, ascertainment included: 14% w/positive universal LS tumor screening, 21% w/early-onset or synchronous LS CA, 14% w/multi-gene panel for PHx of OC, 10% w/incidental MSH6+ result (2 had testing for PHx breast CA, 1 tumor genomic profiling), and 28% w/PHx and/or FHx of LS CA warranting genetic testing. Age of CA onset and path data were verified in > 90% index pts. Results: Index pts had a mean age of 55.5 yrs, and 77% were female. Overall, 11% (5/44) of MSH6+ index pts were found to have LS at diagnosis of synchronous primary CAs (3 EC/OC, 1 CRC/CRC, 1 CRC/EC), and 4/5 of these occurred <50 yrs. An additional 20% (9/44) index pts reported PHx of >2 metachronous LS CAs. OC was the presenting CA in 14% (6/44) female index pts; 2 additional index pts had rarer OC variants (Mullerian duct @ 41, primary peritoneal CA @ 50). Skin manifestations of LS were documented in 9.1% (4/44) index pts (3 sebaceous, 1 SCC in-situ/Bowen’s disease); 1 other family had documented sebaceous CAs in an FDR (father) but the 2 daughters seen @FCCC (both 30s) had yet to develop skin lesions. 2 index pts were found to have LS after developing early-onset breast CA (age 39) and contralateral breast CA (ages 50 and 54). Finally, 7% (3/44) index pts had a PHx of sarcoma: 2 were liposarcomas (ages 57 and 67), and 1 was a dermatofibrosarcoma. 2 other index pts had siblings w/childhood sarcomas. Conclusions: Our data, encompassing 44 MSH6+ pts evaluated in our clinic and consecutively ascertained, suggest MSH6 PV carriers develop synchronous primaries (11%), common and rare OC histologic types (18%), sarcomas (7%) and skin disease/Muir-Torre (9%). While common in the population and lower penetrance for CRC, MSH6 PV can behave in uncommon ways and may have significant extra-colonic CA risks such as OC, sarcoma and skin manifestations.

scholarly journals High-risk human papillomavirus in non-melanoma skin lesions from renal allograft recipients and immunocompetent patients

2011 ◽  
Vol 104 (8) ◽  
pp. 1334-1341 ◽  
Author(s):  
M Reuschenbach ◽  
T Tran ◽  
F Faulstich ◽  
W Hartschuh ◽  
S Vinokurova ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
High Risk ◽  
Renal Allograft ◽  
Skin Lesions ◽  
Immunocompetent Patients ◽  
Melanoma Skin

scholarly journals Intelligent Dermatologist Tool for Classifying Multiple Skin Cancer Subtypes by Incorporating Manifold Radiomics Features Categories

2021 ◽  
Vol 2021 ◽  
pp. 1-14
Author(s):  
Omneya Attallah ◽  
Maha Sharkas
Keyword(s):  
Skin Cancer ◽  
Binary Classification ◽  
Survival Rates ◽  
Skin Lesions ◽  
Accurate Diagnosis ◽  
Computer Assisted ◽  
Discrete Wavelet ◽  
Cancer Subtypes ◽  
Low Level ◽  
High Level

The rates of skin cancer (SC) are rising every year and becoming a critical health issue worldwide. SC’s early and accurate diagnosis is the key procedure to reduce these rates and improve survivability. However, the manual diagnosis is exhausting, complicated, expensive, prone to diagnostic error, and highly dependent on the dermatologist’s experience and abilities. Thus, there is a vital need to create automated dermatologist tools that are capable of accurately classifying SC subclasses. Recently, artificial intelligence (AI) techniques including machine learning (ML) and deep learning (DL) have verified the success of computer-assisted dermatologist tools in the automatic diagnosis and detection of SC diseases. Previous AI-based dermatologist tools are based on features which are either high-level features based on DL methods or low-level features based on handcrafted operations. Most of them were constructed for binary classification of SC. This study proposes an intelligent dermatologist tool to accurately diagnose multiple skin lesions automatically. This tool incorporates manifold radiomics features categories involving high-level features such as ResNet-50, DenseNet-201, and DarkNet-53 and low-level features including discrete wavelet transform (DWT) and local binary pattern (LBP). The results of the proposed intelligent tool prove that merging manifold features of different categories has a high influence on the classification accuracy. Moreover, these results are superior to those obtained by other related AI-based dermatologist tools. Therefore, the proposed intelligent tool can be used by dermatologists to help them in the accurate diagnosis of the SC subcategory. It can also overcome manual diagnosis limitations, reduce the rates of infection, and enhance survival rates.

A Simplified Approach for Melanoma Skin Disease Identification

2021 ◽  
Author(s):  
G. Glorindal ◽  
S. Arun Mozhiselvi ◽  
T. Ananth Kumar ◽  
K. Kumaran ◽  
Phillip Chisomo Katema ◽  
...  
Keyword(s):  
Skin Disease ◽  
Simplified Approach ◽  
Disease Identification ◽  
Melanoma Skin

Chromoblastomycosis in two giant ditch frogs also known as mountain chicken frogs (Leptodactylus fallax)

2019 ◽  
Vol 7 (3) ◽  
pp. e000691
Author(s):  
Martina Croci ◽  
Stefanie Klausmann ◽  
Jean-Michel Hatt ◽  
Sarah Schmitt ◽  
Monika Hilbe
Keyword(s):  
Sudden Death ◽  
Skin Disease ◽  
Fungal Pathogen ◽  
Systemic Disease ◽  
Skin Lesions ◽  
Post Mortem ◽  
Human Beings ◽  
Skeletal Musculature ◽  
Chronic Skin ◽  
Chronic Skin Disease

Because of sudden death of several frogs following the renewal of a terrarium, two giant ditch frogs (Leptodactylus fallax) were submitted for post-mortem examination. The animals displayed extensive erythematous to ulcerative skin lesions as well as multiple granulomas in the liver, kidney and skeletal musculature. In skin lesions as well as in the brownish granulomas, pigmented fungal sclerotic bodies were found in addition to pigmented hyphal structures, though less common. The fungal pathogen, although not further classified in this study was identified as the etiological agent for chromoblastomycosis (synonym: chromomycosis), a leading cause of fatal systemic disease in poikilothermic animals. It is also a cause of chronic skin disease in human beings and therefore a potential zoonotic agent.

scholarly journals The level of acceptance of the illness among patients with psoriasis

2020 ◽  
Vol 66 (3) ◽  
Author(s):  
Kinga Budzińska ◽  
Marta Kożybska ◽  
Paulina Zabielska ◽  
Anna Knyszyńska ◽  
Joanna Pierzak-Sominka ◽  
...  
Keyword(s):  
Body Image ◽  
Skin Disease ◽  
Self Esteem ◽  
Skin Lesions ◽  
The Other ◽  
The Internet ◽  
Great Level ◽  
Factors Affecting ◽  
Acceptance Of Illness ◽  
Psoriatic Lesions

Introduction: Psoriasis is a chronic inflammatory and non-infectious skin disease. It is one of the most common dermatoses. Increased reproduction of the epidermis and, as a consequence, visible skin lesions negatively affect the patient's psyche, disrupt self-esteem, reducing the chance of accepting the disease and a normal life.The aim of this study was the assessment of the level of acceptance of the illness and identification of factors affecting its acceptance among patients with psoriasis.Materials and methods: The study involved 132 individuals, comprising 113 women and 19 men. This survey-based study was conducted via the Internet using the author's questionnaire and the Acceptance of Illness Scale (AIS).Results: Acceptance of the illness level was rated great and moderate by respectively 43.9% and 39.4% of respondents. Over 66.7% of the patients described their self-esteem as high obtained a great level of acceptance of the illness according to the AIS. In the examined group, 58% of the patients not accepted psoriatic lesions on their body. Over 60% of the respondents experienced negative reactions from society regarding the disease, and almost 50% of them experienced other people’s reactions resulting from concerns about contracting the disease; these patients obtained lower AIS scores.Conclusions: The obtained results indicate a great illness acceptance among the examined group of the patients with psoriasis. The level of acceptance was influenced by the patient’s self-esteem in relation to the disease, acceptance of their own body image, altered by the disease, experiencing the negative reactions from the society regarding the disease, and the reactions of the other people resulting from concerns about contracting the disease.

scholarly journals Skin cancers in people with albinism in Togo in 2019: results of two rounds of national mobile skin care clinics

2020 ◽  
Author(s):  
Bayaki Saka ◽  
Sefako Abla Akakpo ◽  
Julienne Noude Teclessou ◽  
Piham Gnossike ◽  
Saliou Adam ◽  
...  
Keyword(s):  
Medical Records ◽  
Skin Lesions ◽  
Cross Sectional Study ◽  
Skin Care ◽  
Ultraviolet Rays ◽  
Cross Sectional ◽  
Protection Measures ◽  
Skin Cancers ◽  
High Prevalence ◽  
Melanoma Skin

Abstract Background: In people with albinism (PWA), the deficiency of melanin increase the risk of skin cancer. The aim of this study was to determine the prevalence of skin cancers and characteristics of these detected skin cancers (histological types, localization,) in PWA in 10 cities in Togo in 2019.Methods: This is a cross-sectional study of medical records of PWA systematically examined during two mobile skin care clinics in 2019, as part of a programme for the prevention and management of skin cancers in these subjects. Results: During the study period, 280 (95.2%) of the 294 PWA consulted, had developed skin lesions. Of the 280 PWA, the pathological reports from the medical records of 33 patients (11.8%; (95%CI= [8.2-16.2]) had concluded to non-melanoma skin cancers. The mean age of these 33 patients was 38.6±15.2 years and the sex-ratio was 1. Their occupations were mainly resellers (21.2%), traders (15.2%) and farmers (12.2%). In the 33 patients, 54 cases of non-melanoma skin cancers were identified, with some patients having more than one tumor, and some of them having more than one (histologically confirmed) diagnosis. These 54 non-melanoma skin cancers were divided into 21 cases of invasive squamous cell carcinomas, 2 cases of Bowen’s disease and 31 cases of basal cell carcinomas. These non-melanoma skin cancers mainly occurred in the head and neck (33 cases; 61.1%), the upper limbs (15 cases; 27, 8%) and the trunk (4 cases; 7.4%).Conclusion: The results of this study show a high prevalence of skin cancers among PWAs in Togo in 2019, only non-melanoma skin cancers. In addition, they illustrate the role of ultraviolet rays with regard to the localization of skin cancers and the occupations of patients. Popularization and compliance with photo protection measures, systematic and regular examination of the skin of these PWAs will allow early detection and treatment of these skin cancers.

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