Nomegestrol acetate is an anti-aromatase agent in human MCF-7aro breast cancer cells
2010 ◽
Vol 3
(2)
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Keyword(s):
Abstract: The progestogen nomegestrol acetate (NOMAC), a 17α-hydroxy-nor-progesterone derivative (LUTENYL: Cells were incubated with physiological concentrations of androgen substrates [: Aromatase activity levels are high in MCF-7aro cells because the [: The MCF-7aro cell line shows high aromatase activity and NOMAC can act as an anti-aromatase agent by inhibiting this activity. This is an important new effect of this progestogen. Because NOMAC can also inhibit sulfatase activity in breast cancer cells, we suggest that this dual effect of NOMAC has attractive possibilities for clinical trials.
The Impact of Antioxidants from the Diet on Breast Cancer Cells Monitored by Raman Microspectroscopy
2018 ◽
Vol 16
(2)
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pp. 127-137
Keyword(s):
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2019 ◽
Vol 62
(3)
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pp. R201-R222
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Keyword(s):
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2005 ◽
Vol 93
(1)
◽
pp. 1-13
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1996 ◽
Vol 58
(5-6)
◽
pp. 525-531
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1997 ◽
Vol 11
(sup1)
◽
pp. 69-75
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