scholarly journals Analysis of an M/G/1 Stochastic Clearing Queue in a 3-Phase Environment

2015 ◽  
Vol 3 (4) ◽  
pp. 374-384
Author(s):  
Xiaoyan Zhang ◽  
Liwei Liu ◽  
Tao Jiang
Keyword(s):  
Phase 1 ◽  
Fixed Time ◽  
Second Phase ◽  
Single Server ◽  
Exponential Distributions ◽  
Variable Technique ◽  
Phase 3 ◽  
Time Length ◽  
Third Phase ◽  
Sojourn Time Distribution

AbstractThis paper studies a single server M/G/1 stochastic clearing queue operating in a 3-phase environment, where the time length of the first and third phase are assumed to follow exponential distributions, and the time length of the second phase is a constant value. At the completion of phase 1, the system moves to phase 2, and after a fixed time length, the system turns to phase 3. At the end of phase 3, all present customers in the system are forced to leave the system, then the system moves to phase 1 and restarts a new service cycle. Using the supplementary variable technique, we obtain the distribution for the stationary queue at an arbitrary epoch. We also derive the sojourn time distribution and the length of the server’s working time in a cycle.

PENERAPAN MODEL QUANTUM LEARNING UNTUK MENINGKATKAN HASIL BELAJAR AUTOCAD SISWA KELAS X TEKNIK PEMESINAN SMK NEGERI 1 STABAT

2013 ◽  
Vol 5 (1) ◽  
Author(s):  
Abdul Hasan Saragih
Keyword(s):  
Positive Response ◽  
Phase 1 ◽  
First Grade ◽  
Learning Model ◽  
Second Phase ◽  
Phase 2 ◽  
Phase 3 ◽  
The Third ◽  
Third Phase ◽  
Quantum Learning

This classroom research was conducted on the autocad instructions to the first grade of mechinary class of SMK Negeri 1 Stabat aiming at : (1) improving the student’ archievementon autocad instructional to the student of mechinary architecture class of SMK Negeri 1 Stabat, (2) applying Quantum Learning Model to the students of mechinary class of SMK Negeri 1 Stabat, arising the positive response to autocad subject by applying Quantum Learning Model of the students of mechinary class of SMK Negeri 1 Stabat. The result shows that (1) by applying quantum learning model, the students’ achievement improves significantly. The improvement ofthe achievement of the 34 students is very satisfactory; on the first phase, 27 students passed (70.59%), 10 students failed (29.41%). On the second phase 27 students (79.41%) passed and 7 students (20.59%) failed. On the third phase 30 students (88.24%) passed and 4 students (11.76%) failed. The application of quantum learning model in SMK Negeri 1 Stabat proved satisfying. This was visible from the activeness of the students from phase 1 to 3. The activeness average of the students was 74.31% on phase 1,81.35% on phase 2, and 83.63% on phase 3. (3) The application of the quantum learning model on teaching autocad was very positively welcome by the students of mechinary class of SMK Negeri 1 Stabat. On phase 1 the improvement was 81.53% . It improved to 86.15% on phase 3. Therefore, The improvement ofstudent’ response can be categorized good.

scholarly journals City-To-City Learning for Urban Resilience: The Case of Water Squares in Rotterdam and Mexico City

Water ◽  
2019 ◽  
Vol 11 (5) ◽  
pp. 983 ◽  
Author(s):  
Silvana Ilgen ◽  
Frans Sengers ◽  
Arjan Wardekker
Keyword(s):  
Urban Communities ◽  
Mexico City ◽  
Phase 1 ◽  
Knowledge Exchange ◽  
Second Phase ◽  
Urban Resilience ◽  
Phase 3 ◽  
Third Phase ◽  
The Face ◽  
Local Leaders

Cities worldwide are building ‘resilience’ in the face of water-related challenges. International networks have emerged through which urban communities draw on each other’s experiences and expertise in order to become resilient cities. Learning is a key principle in resilience-building, but thus far little empirical research is available on city-to-city learning and learning for urban resilience. This paper presents an analysis of how policy relevant knowledge on the notion of ‘Water Squares’ is exchanged between Rotterdam and Mexico City. We mobilize a framework composed of four distinct phases: exploration and marketing (phase 1), building pipelines (phase 2), translation and adoption (phase 3), and internalization and reflection (phase 4). Critical in first phase was introspective analysis of one’s own systems, strengths and weaknesses, rather than an outward-looking search for knowledge or mentees. During the second phase, the cities reframed their own narratives to match those of their counterparts as a way to create a mutual understanding of each other’s struggles and histories. This facilitated policy and knowledge exchange as equal partners on a basis of trust. In the third phase, strong local leaders were recruited into the process, which was key to anchor knowledge in the community and to reduce the risks of losing institutional memory in centralized, hierarchical institutions. For the fourth phase it should be stressed that by internalizing such lessons, cities might strengthen not only their own resilience, but also enhance future exchanges with other cities.

ON THE DOUBLING DISTRIBUTIONS OF DAY 7-MEGAKARYOCYTE (MKC) PROGENITORS

1987 ◽  
Author(s):  
J M Paulus ◽  
R Fernandez-Delgado ◽  
J C Grosdent ◽  
J Lecocq ◽  
M Prenant
Keyword(s):  
Bone Marrow ◽  
Conditioned Medium ◽  
Renewal Process ◽  
Coefficient Of Variation ◽  
Phase 1 ◽  
Renewal Theory ◽  
Fixed Time ◽  
Mouse Bone Marrow ◽  
Exponential Distributions ◽  
Significant Variability

It has often been assumed that hemopoietic progenitors undergo a rather uniform, deterministic number of proliferative cycles before they generate the elements which are recognizable by pano-ptiG and cytochemical methods. We now confirm and extend previous data on the distribution of the number of doublings undergone before polyploi'dization by day 7-MKC progenitors. Cultures of mouse bone marrow were stimulated by erythropoietin, WEHI conditioned medium (CM) and/or pokeweed CM. In all cases, cumulative doubling distributions of pure MKC colonies could be precisely fitted by exponential lines, whose slope and length depended on the stimulus or combination of stimuli used. The frequency of single MKC could be fitted by the same line as that plotting the number of doublings in MKC colonies, suggesting that single MKC and MKC colonies can be generated by the same class of progenitors. Exponential shape implies that the coefficient of variation (SD/mean) of doubling numbers is one, indicating significant variability in proliferative behavior among day 7-MKC progenitors. Such exponential distributions are best explained in the framework of Renewal Theory (Cox, Methuen, 1962). Whatever the distribution of the number of progenitor renewals in fixed time, the distribution of renewals will be geometric (i.e discontinuous exponential) if the total time spent by individual colonies in the proliferation phase (1) is distributed exponentially, and (2) is independent from the renewal process itself. These results suggest that the wave of MKC progenitor mitoses is randomly arrested by a differentia-tive event which strikes progenitor clones independently from their proliferative past.

Abstract 9386: Ramp Biphasic Waveforms Have a Lower External Defibrillation Threshold

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Jian Huang ◽  
Gregory P Walcott ◽  
Raymond E Ideker
Keyword(s):  
Phase 1 ◽  
Second Phase ◽  
Phase 2 ◽  
Defibrillation Threshold ◽  
Phase 3 ◽  
Peak Voltage ◽  
Biphasic Waveform ◽  
Internal Defibrillation

Introduction: We have previously shown that waveforms with an ascending ramp in both phases have a lower internal defibrillation threshold (DFT). The purpose of this study was to test whether waveforms with rectilinear, ascending and descending ramps in the second phase would reduce the DFT compared with a standard exponential biphasic waveform with external defibrillation shocks. Methods: In 6 pigs, DFTs were determined for 10 waveforms: a standard truncated exponential biphasic waveform with 60% tilt (Fig 1, #1) and 9 biphasic waveforms with an 8 ms ascending ramp 1st phase and one of 3 rectilinear, ascending ramp or descending ramp 2nd phases. The 3 rectilinear 2nd phases were: 1 ms, 200% of peak voltage of phase 1 (#2); 2 ms, same voltage as phase (#3); 3 ms, half the voltage of phase 1 (#4). The 3 ascending ramp 2nd phases were: 2 ms, 200% of voltage of phase 1(#5); 3 ms, same voltage as phase 1(#6); 4.5 ms, half the voltage of phase 1(#7). The 3 descending ramp 2nd phases were: 2 ms, 200% of voltage of phase 1(#8); 3 ms, same voltage as phase 1(#9); 4.5 ms, half the voltage of phase 1(#10). Results: Phase 2 ascending ramp (#7) and descending ramp (#8, #9) waveforms had the lowest DFTs, which were significantly smaller than for the truncated exponential waveform. (Fig 1, *indicates p<0.05). Conclusions: Waveforms with a ramp in phase 2 (#7, #8, #9) have a lower DFT.

Excavations on the Leven, Loudoun Hill, Ayrshire, 1993

2000 ◽  
Vol 22 (1) ◽  
pp. 31-68 ◽  
Author(s):  
JOHN A. ATKINSON ◽  
DIANE ALDRITT ◽  
IAIN BANKS ◽  
MIKE DONNELLY ◽  
FRASER HUNTER ◽  
...  
Keyword(s):  
Iron Age ◽  
Primary Phase ◽  
Second Phase ◽  
Timber Structures ◽  
Neolithic Period ◽  
Phase 2 ◽  
Early Neolithic ◽  
Phase 3 ◽  
Third Phase ◽  
Internal Structures

Rescue excavations at Loudoun Hill Quarry revealed the remains of timber structures, defined as pits and postholes in the subsoil. A primary phase of activity was represented by two pits which are tentatively dated to the early Neolithic period by association with artefactual and botanical evidence. The second phase of occupation at the site was represented by the construction of a double palisaded enclosure. A third phase of activity is postulated by the construction of a second and larger double palisaded enclosure which contained internal structures. Phase 3 is dated by association with artefactual material to the Iron Age. The fourth phase of activity at the site was represented by an enclosure defined by a fence slot which overlay the phase 2 enclosure. The most remarkable small find was a pair of decorated bronze tweezers.

An Evidence-based Approach to Developing the Collaborative, Client-Centred Nutrition Education (3CNE) Framework and Practice Points

2016 ◽  
Vol 77 (2) ◽  
pp. 78-83 ◽  
Author(s):  
Catherine Morley ◽  
Deborah MacLellan ◽  
Karol Traviss ◽  
Theresa Cividin
Keyword(s):  
Nutrition Education ◽  
Online Survey ◽  
Phase 1 ◽  
Phase 2 ◽  
Phase 3 ◽  
Progressive Development ◽  
Third Phase ◽  
Phase Study ◽  
Subsequent Phase ◽  
Phase Phase

Purpose: The purpose of this, the third phase of a 3-phase research project, was to develop guidelines for client-centred nutrition education (NE). Methods: A 3-phase study was conducted using a progressive development design, where each phase informed the subsequent phase. Phase 1 was a national online survey of dietitians’ perceptions of consumers’ NE needs and preferences; results informed the Phase 2 national online survey of consumers about their NE needs and preferences. Phase 3 involved national 2-part teleconference consultations with dietitians to discuss implications of the Phase 2 findings for NE practice. This paper is the report of Phase 3. Results: Discussion group participants were 22 dietitians from around Canada who had been in practice for an average of 14.5 years. Discussions resulted in the development of the Collaborative Client-Centred Nutrition Education (3CNE) conceptual framework and related Practice Points that explicate the complexity of NE practice. Conclusion: The 3CNE framework and Practice Points provide a means to inform precepting students and interns, and for use in planning for the professional development of practicing dietitians on providing client-centred NE.

scholarly journals The Effects of an In-vehicle Collision Warning System on Older Drivers' On-road Head Movements at Intersections

2021 ◽  
Vol 12 ◽  
Author(s):  
Rachel Shichrur ◽  
Navah Z. Ratzon ◽  
Arava Shoham ◽  
Avinoam Borowsky
Keyword(s):  
Phase 1 ◽  
Warning System ◽  
Head Movements ◽  
Older Drivers ◽  
Movement Behavior ◽  
Second Phase ◽  
Phase 3 ◽  
Baseline Phase ◽  
Collision Warning ◽  
Old Adult

With age might come a decline in crucial driving skills. The effect of a collision warning system (CWS) on older drivers' head movements behavior at intersections was examined.Methods: Twenty-six old-adults, between 55 and 64 years of age, and 16 Older drivers between 65 and 83 years of age, participated in the study. A CWS (Mobileye Inc.) and a front-back in-vehicle camera (IVC) were installed in each of the participants' own vehicles for 6 months. The CWS was utilized to identify unsafe events during naturalistic driving situations, and the IVC was used to capture head direction at intersections. The experimental design was conducted in three phases (baseline, intervention, and carryover), 2 months each. Unsafe events were recorded by the CWS during all phases of the study. In the second phase, the CWS feedback was activated to examine its effect on drivers' head movement' behavior at intersections.Results: Older drivers (65+) drove significantly more hours in total during the intervention phase (M = 79.1 h, SE = 10) than the baseline phase (M = 39.1 h, SE = 5.3) and the carryover phase (M = 37.7 h, SE = 5.4). The study revealed no significant differences between the head movements of older and old-adult drivers at intersections. For intersection on the left direction, a significant improvement in drivers' head movements' behavior was found at T-junctions, turns and four-way intersections from phase 1 to phase 3 (p &lt; 0.01), however, two intersection types presented a decrease along the study phases. The head movements' behavior at roundabouts and merges was better at phase 1 compared to phase 3 (p &lt; 0.01). There was no significant reduction of the mean number of CWS unsafe events across the study phases.Conclusions: The immediate feedback provided by the CWS was effective in terms of participants' head movements at certain intersections but was harmful in others. However, older drivers drove many more hours during the active feedback phase, implying that they trusted the system. Therefore, in the light of this complex picture, using the technological feedback with older drivers should be followed with an additional mediation or follow-up to ensure safety.

Clinical Drug Development for the Treatment of Pulmonary Arterial Hypertension: Collaboration With the Pharmaceutical Industry and Regulatory Agencies

2010 ◽  
Vol 9 (4) ◽  
pp. 214-219
Author(s):  
Robyn J. Barst
Keyword(s):  
Clinical Trials ◽  
Pulmonary Arterial Hypertension ◽  
Drug Development ◽  
Phase 1 ◽  
Preclinical Studies ◽  
Phase 2 ◽  
Phase 3 ◽  
Preclinical Testing ◽  
New Drug ◽  
Pulmonary Arterial

Drug development is the entire process of introducing a new drug to the market. It involves drug discovery, screening, preclinical testing, an Investigational New Drug (IND) application in the US or a Clinical Trial Application (CTA) in the EU, phase 1–3 clinical trials, a New Drug Application (NDA), Food and Drug Administration (FDA) review and approval, and postapproval studies required for continuing safety evaluation. Preclinical testing assesses safety and biologic activity, phase 1 determines safety and dosage, phase 2 evaluates efficacy and side effects, and phase 3 confirms efficacy and monitors adverse effects in a larger number of patients. Postapproval studies provide additional postmarketing data. On average, it takes 15 years from preclinical studies to regulatory approval by the FDA: about 3.5–6.5 years for preclinical, 1–1.5 years for phase 1, 2 years for phase 2, 3–3.5 years for phase 3, and 1.5–2.5 years for filing the NDA and completing the FDA review process. Of approximately 5000 compounds evaluated in preclinical studies, about 5 compounds enter clinical trials, and 1 compound is approved (Tufts Center for the Study of Drug Development, 2011). Most drug development programs include approximately 35–40 phase 1 studies, 15 phase 2 studies, and 3–5 pivotal trials with more than 5000 patients enrolled. Thus, to produce safe and effective drugs in a regulated environment is a highly complex process. Against this backdrop, what is the best way to develop drugs for pulmonary arterial hypertension (PAH), an orphan disease often rapidly fatal within several years of diagnosis and in which spontaneous regression does not occur?

Mixed-Methods Evaluation as Scaffold to the Development of a Mobile Health Application to Support the Prescription of Wheelchairs and Postural Support Devices (Preprint)

2020 ◽  
Author(s):  
Adriana Klein ◽  
Roseli de Deus Lopes ◽  
Rodrigo Suigh
Keyword(s):  
Mixed Methods ◽  
Mobile Health ◽  
Second Phase ◽  
The Third ◽  
Evaluation Approach ◽  
Mixed Methods Evaluation ◽  
Usability Tests ◽  
Third Phase ◽  
Postural Support ◽  
Support Devices

BACKGROUND EasySeating is a mobile health (mHealth) app that supports the prescription of wheelchair and postural support devices (WPSD). It can be used by occupational therapists (OT) and physiotherapists (PT) who prescribe WPSD. The app offers a standardization of the prescription procedure, showing images, metrics and details that guide the prescriber to decide on the best equipment. It was developed with an iterative mixed-methods evaluation approach. Objective: The aim of this study was to investigate the processes involved in the prescription of WPSD and to propose, develop and evaluate a mHealth to support OT and PT prescribers. OBJECTIVE The aim of this study was to investigate the processes involved in the prescription of WPSD and to propose, develop and evaluate a mHealth to support OT and PT prescribers. METHODS This study was divided into three phases and was carried out as an iterative process composed of user consulting/testing (using a mixed-methods evaluation approach), system (re)design and software development. The first phase consisted of the collection of qualitative and quantitative data to map and understand the users requirements and of the development of the first prototype (v1) of the app. This data collection was performed through semi-structured interviews with 14 OT and PT prescribers, 5 specialized technicians and 5 WPSD users. The second phase aimed at improving the overall functionality of the app and consisted in the development, test and evaluation of the prototypes v1, v2, v3 and v4. A total of 59 prescribers tested and evaluated these prototypes by means of open interviews, semi-structured questionnaires and focus groups. The third phase focused in the usability aspects of the app. It consisted in the development and test of the prototype v5. Eight technology specialists assessed its usability through heuristics evaluation. RESULTS Data collected in phase one indicated there is a lack of standardization on the prescription of postural support devices (PSD). A divergent nomenclature for the PSDs was also found and classified in eight categories. These information guided the development of the first prototype of the EasySeating app. Phase two results pointed that the prescribers value the insertion of the app into their clinical practice, as it accelerates and increases the quality of the evaluation process and improves the organization of the prescription information. Significant suggestions for the improvement of the app were given during the users tests, including the use of images to represent the PSDs. The usability tests from the third phase revealed two strong issues that must be solved: the need of greater feedback and failures in the persistence of the input data. CONCLUSIONS This study demonstrated that there is a lack of systematization of the WPSD prescription process. The evaluation of the developed EasySeating app demonstrated that there is a potential to standardize, integrate and organize the WPSD prescription information, supporting and facilitating the decision making process of the prescribers. CLINICALTRIAL This study was approved by the Research Ethics Board of the Universidade de São Paulo (registered protocol n°53929516.6.0000.0065) URL - http://plataformabrasil.saude.gov.br/login.jsf

Foucault as Superauthor

2019 ◽  
Vol 29 (2) ◽  
pp. 104-125
Keyword(s):  
Free Speech ◽  
Second Phase ◽  
Contemporary Society ◽  
Sovereign Power ◽  
Ancient Greek ◽  
Main Motivation ◽  
Critical Attitude ◽  
The Third ◽  
Third Phase ◽  
Lecture Courses

Three phases in Foucault’s examination of authorship and free speech were essential to him throughout his life. They can be linked to such texts as the three lectures “What is an Author?” (first phase), “What is Critique?,” and “What is Revolution?” (second phase), and the two lecture courses, “Fearless Speech,” and “The Courage of Truth” (third phase). Initially, Foucault merely describes the founders of discursivity (hence, “superauthors”), among whom he reckoned only Marx and Freud, as the sole alternative to his own conceptualization of the author function, which is exhibited en masse in contemporary society. He then modifies his views on superauthorship by making Kant the paradigm and by linking his own concept of free speech to a Kan-tian critical attitude. However, Foucault claims only the half of Kant’s philosophical legacy that is related to the study of the ontology of the self.The article advances the hypothesis that the sovereign power of speech, which can be found in Marx and Heidegger and in generally in the concept of “superauthorship,” becomes unacceptable for Foucault. During the third phase, the danger of a tyrannical use of free speech compels Foucault to make a number of fruitful but questionable choices in his work. He focuses on a single aspect of free speech in which a speaker is in a weaker position and therefore has to overcome his fear in order to tell the truth. Foucault associates this kind of free speech with the ancient Greek notion of parrhesia, which according to his interpretation means “fearless speech”; however, this reading is not always supported by the ancient Greek sources. Foucault’s deliberations bring him to the radical conclusion that free speech transforms into performative “aesthetics of existence.” Foucault’s main motivation for pursuing this line of thought all through his life was to investigate his own abilities and powers as an author

Sign in / Sign up

Export Citation Format

Share Document