scholarly journals Can exchange transfusion be replaced by double-LED phototherapy?

Open Medicine ◽  
2021 ◽  
Vol 16 (1) ◽  
pp. 992-996
Author(s):  
Shinya Abe ◽  
Kazumichi Fujioka
Keyword(s):  
Exchange Transfusion ◽  
Light Emitting Diode ◽  
Safe Procedure ◽  
Light Emitting ◽  
Safety Issues ◽  
Led Phototherapy ◽  
Recent Developments ◽  
Good Treatment Strategy ◽  
Severe Hyperbilirubinemia

Abstract Phototherapy is a conventional treatment for neonatal jaundice and widely considered as a safe procedure. Recent developments in light-emitting diode (LED) phototherapy devices have made more effective treatments possible. Exchange transfusion (ET) is typically applied for cases of refractory severe hyperbilirubinemia despite its risk of various complications. Since the therapeutic effect of phototherapy is correlated with its irradiance, ET may be avoided by performing phototherapy with higher irradiation. Recently, we adopted double-LED phototherapy as a bridging treatment to ET to treat a case of severe hyperbilirubinemia. In this case, the continual increase of bilirubin levels was suppressed immediately after its administration, and ET was not required. Throughout the treatment, no complications or increase in oxidative stress was observed. In addition, neurodevelopment was appropriate for the patient’s age at the 1-year follow-up, and no findings of kernicterus, including physical and magnetic resonance imaging findings, were observed. We hypothesized that double-LED phototherapy may be a good treatment strategy to replace ET for infants with severe hyperbilirubinemia; however, further investigations regarding safety issues including acute and long-term complications are needed before clinical adaptation.

scholarly journals Reflectance-Based Organic Pulse Meter Sensor for Wireless Monitoring of Photoplethysmogram Signal

Biosensors ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. 87 ◽  
Author(s):  
Fahed Elsamnah ◽  
Anubha Bilgaiyan ◽  
Muhamad Affiq ◽  
Chang-Hoon Shim ◽  
Hiroshi Ishidai ◽  
...  
Keyword(s):  
Power Consumption ◽  
Structural Design ◽  
Signal To Noise Ratio ◽  
Light Emitting Diode ◽  
Light Emitting ◽  
Organic Light Emitting Diode ◽  
Wireless Monitoring ◽  
Organic Light ◽  
Reduced Power Consumption

This paper compares the structural design of two organic biosensors that minimize power consumption in wireless photoplethysmogram (PPG) waveform monitoring. Both devices were fabricated on the same substrate with a red organic light-emitting diode (OLED) and an organic photodiode (OPD). Both were designed with a circular OLED at the center of the device surrounded by OPD. One device had an OLED area of 0.06 cm2, while the other device had half the area. The gap distance between the OLED and OPD was 1.65 mm for the first device and 2 mm for the second. Both devices had an OPD area of 0.16 cm2. We compared the power consumption and signal-to-noise ratio (SNR) of both devices and evaluated the PPG signal, which was successfully collected from a fingertip. The reflectance-based organic pulse meter operated successfully and at a low power consumption of 8 µW at 18 dB SNR. The device sent the PPG waveforms, via Bluetooth low energy (BLE), to a PC host at a maximum rate of 256 kbps data throughput. In the end, the proposed reflectance-based organic pulse meter reduced power consumption and improved long-term PPG wireless monitoring.

scholarly journals Toluidine blue O and porphyrin-mediated photodynamic therapy on three main pathogenic bacteria of periodontitis using portable LED phototherapy device

2015 ◽  
Vol 08 (04) ◽  
pp. 1550017 ◽  
Author(s):  
Xuewei Jiang ◽  
Zhichao Fan ◽  
Yili Yu ◽  
Chenying Shao ◽  
Yuanzhen Suo ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Toluidine Blue ◽  
Pathogenic Bacteria ◽  
Light Emitting Diode ◽  
Red Light ◽  
In Vitro Screening ◽  
Light Emitting ◽  
Led Phototherapy ◽  
Prevotella Melaninogenica

Photodynamic therapy (PDT) has been commonly used in treating many diseases, such as cancer and infectious diseases. We investigated the different effects of PDT on three main pathogenic bacteria of periodontitis — Prevotella melaninogenica (P.m.), Porphyromonas gingivalis (P.g.) and Aggregatibacter actinomycetemcomitans (A.a.). The portable red light-emitting diode (LED) phototherapy device was used to assess the exogenous PDT effects with different light doses and photosensitizer concentrations (Toluidine blue O, TBO). The portable blue LED phototherapy device was used to assess the endogenous PDT effects with the use of endogenous photosensitizers (porphyrin) under different light doses. We found out that both exogenous and endogenous PDT were able to restrict the growth of all the three bacteria significantly. Moreover, the optimal PDT conditions for these bacteria were obtained through this in vitro screening and could guide the clinical PDT on periodontitis.

A Novel Voltage-Programmed Pixel Circuit with Poly-Si TFTs for AMOLED Displays

2018 ◽  
Vol 27 (14) ◽  
pp. 1850221
Author(s):  
Zunkai Huang ◽  
Li Tian ◽  
Hui Wang ◽  
Songlin Feng
Keyword(s):  
Threshold Voltage ◽  
Light Emitting Diode ◽  
Active Matrix ◽  
Light Emitting ◽  
Organic Light Emitting Diode ◽  
Electrical Stress ◽  
Organic Light ◽  
Pixel Circuit ◽  
Display Performance

In this paper, we propose a novel voltage-programmed pixel circuit with polysilicon thin–flim transistors (poly-Si TFTs) for active matrix organic light-emitting diode (AMOLED) displays, which consists of one programming transistor, one driving transistor, four switching transistors and two storage capacitors, respectively. Specifically, the proposed pixel circuit is able to not only efficiently compensate for the threshold variations of TFTs, but also largely suppresses the electrical degradations of the devices caused by the long-term electrical stress. Moreover, the mobility variation of the driving transistor can be compensated as well. The simulation has been performed by HSPICE, and results indicate that the average values of nonuniformities are, respectively, 7.3% as the threshold-voltage varies by [Formula: see text][Formula: see text]V and 2.1%, as the mobility of the driving transistor varies by [Formula: see text]%, both of which are much lower than that of the conventional two-transistor and one-capacitor (2T1C) pixel. Furthermore, since the OLED is reverse-biased during the nonemission phases, the lifetime of OLED will be extended naturally. As a consequence, the proposed pixel circuit can substantially improve the display performance.

Effect of the laser and light-emitting diode (LED) phototherapy on midpalatal suture bone formation after rapid maxilla expansion: a Raman spectroscopy analysis

2013 ◽  
Vol 29 (3) ◽  
pp. 859-867 ◽  
Author(s):  
Cristiane Becher Rosa ◽  
Fernando Antonio Lima Habib ◽  
Telma Martins de Araújo ◽  
Juliana Silveira Aragão ◽  
Rafael Soares Gomes ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Bone Formation ◽  
Light Emitting Diode ◽  
Spectroscopy Analysis ◽  
Midpalatal Suture ◽  
Light Emitting ◽  
Led Phototherapy

scholarly journals Long-term NO<sub>x</sub> measurements in the remote marine tropical troposphere

2020 ◽  
Author(s):  
Simone T. Andersen ◽  
Lucy J. Carpenter ◽  
Beth S. Nelson ◽  
Luis Neves ◽  
Katie A. Read ◽  
...  
Keyword(s):  
Time Series ◽  
Light Emitting Diode ◽  
Ultra Violet ◽  
Data Set ◽  
Light Emitting ◽  
Mixing Ratios ◽  
Remote Troposphere ◽  
Tropical Troposphere ◽  
Term Data

Abstract. Atmospheric nitrogen oxides (NO + NO2 = NOx) have been measured at the Cape Verde Atmospheric Observatory (CVAO) in the tropical Atlantic (16° 51' N, 24° 52' W) since October 2006. These measurements represent a unique time series of NOx in the background remote troposphere. Nitrogen dioxide (NO2) is measured via photolytic conversion to nitric oxide (NO) by ultra violet light emitting diode arrays followed by chemiluminescence detection. Since the measurements began, a blue light converter (BLC) has been used for NO2 photolysis, with a maximum spectral output of 395 nm from 2006–2015 and of 385 nm from 2015. The original BLC used was constructed with a Teflon-like material and appeared to cause an overestimation of NO2 when illuminated. To avoid such interferences, a new additional photolytic converter (PLC) with a quartz photolysis cell (maximum spectral output also 385 nm) was implemented in March 2017. Once corrections are made for the NO2 artefact from the original BLC, the two NO2 converters are shown to give comparable NO2 mixing ratios (PLC = 0.92 × BLC, R2 = 0.92), giving confidence in the quantitative measurement of NOx at very low levels. Data analysis methods for the NOx measurements made at CVAO have been developed and applied to the entire time series to produce an internally consistent and high quality long-term data set. NO has a clear diurnal pattern with a maximum mixing ratio of 2–10 pptV during the day depending on the season and ~0 pptV during the night. NO2 shows a fairly flat diurnal signal, although a small increase in daytime NOx is evident in some months. Monthly average mixing ratios of NO2 vary between 5 and 30 pptV depending on the season. Clear seasonal trends in NO and NO2 levels can be observed with a maximum in autumn/winter and a minimum in spring/summer.

scholarly journals Effectiveness of light emitting diode versus conventional phototherapy in neonatal hyperbilirubinemia: a hospital based observational study

2020 ◽  
Vol 8 (3) ◽  
pp. 1051
Author(s):  
Radheshyam Purkait ◽  
Manik Mondal
Keyword(s):  
Side Effects ◽  
Light Emitting Diode ◽  
Total Duration ◽  
Conventional Group ◽  
Light Sources ◽  
Fluorescent Lamp ◽  
Light Emitting ◽  
Led Phototherapy ◽  
Significant Difference ◽  
Compact Fluorescent Lamp

Background: The most commonly used light sources in the conventional phototherapy units are compact fluorescent lamp (CFL), halogen spotlights and fiberoptic blankets. Recently light emitting diodes (LED) has emerged as better light source for phototherapy and almost replacing all the available conventional light sources. Comparative studies on the efficacy of LED versus conventional phototherapy are limited from India. That is why; this study was undertaken.Methods: 48 neonates of ≥35 weeks gestational age with hyperbilirubinemia were participated in this study. Among them, 24 neonates received conventional phototherapy and rest of them received LED phototherapy. The rate of fall of bilirubin levels at 6 hours and at completion along with total duration of phototherapy in both groups was measured. Results analysed by standard statistical methods.Results: LED phototherapy units showed higher rate of fall in bilirubin at six hrs (LED group: 0.38±0.05 mg/dl/hr versus conventional group: 0.30±0.04 mg/dl/hr, p<0.05) and after completion of therapy (LED group:                      0.32±0.03 mg/dl/hr versus conventional group: 0.26±0.03 mg/dl/hr, p<0.05) compared to conventional group. Significant difference was documented in total duration of phototherapy in LED group (30.8±1.8 hours) when compared to conventional group (34.6±0.7 hours). None of the neonate showed phototherapy failure. Side effects were minimal and comparable in both the groups.Conclusions: The LED phototherapy units are more efficacious in terms of higher rate of fall of bilirubin levels and lesser duration of phototherapy compared to conventional phototherapy units.

scholarly journals Highly Luminescent Silver-Based MOFs: Scalable Eco-Friendly Synthesis Paving the Way for Photonics Sensors and Electroluminescent Devices

2020 ◽  
Author(s):  
Mario Gutierrez ◽  
Cristina Martín ◽  
Barbara Souza ◽  
Mark Van der Auweraer ◽  
Johan Hofkens ◽  
...  
Keyword(s):  
Light Emitting Diode ◽  
Metal Organic Framework ◽  
Cost Effective ◽  
One Pot ◽  
Light Emitting ◽  
Metal Organic ◽  
Potential Impact ◽  
Scalable Synthesis ◽  
Potential Use

<p><a></a>Luminescent multifunctional nanomaterials are important because of their potential impact on the development of key technologies such as smart luminescent sensors and solid-state lightings. To be technologically viable, the luminescent material needs to fulfil a number of requirements for integration into real-world devices: facile and cost-effective fabrication, a high quantum yield, structural robustness, and long-term chemical stability. To achieve these requirements, an eco-friendly and scalable synthesis of a highly photoluminescent, multistimuli responsive and electroluminescent silver-based metal-organic framework (Ag-MOF), termed “OX-2” was developed. The high synthetic yield (at least 10 g of purely crystalline OX-2 via one pot reaction), together with its exceptional photophysical and mechanically resilient properties that can be reversibly switched by temperature and pressure make this material stood out over other competing luminescent materials. The potential use of OX-2 MOF as a good electroluminescent material was tested by constructing a proof-of-concept MOF-LED (Light Emitting Diode) device, further contributing to the rare examples of electroluminescent MOFs known to date. The results reveal the huge potential for exploiting the highly luminescent Ag MOF, where OX-2 may serve as a multitasking platform to engineer innovative photonic technologies.</p>

Sign in / Sign up

Export Citation Format

Share Document