CdTe quantum dots on gold-198 nano particles: introducing a novel theranostic agent

AbstractThe influence of coating a CdTe quantum dots (QDs) layer on the 198Au nanoparticles (NPs) in biodistribution of 198Au nanoparticles was investigated. The 198Au nanoparticles were prepared by irradiating the highly pure metallic gold in Tehran research nuclear reactor and subsequently 198Au-NPs were synthesized and subjected to surface modification with cysteamine and CdTe QDs to form an adduct. The prepared nanomaterials were characterized with X-ray diffraction, radio thin layer chromatography, transmission electron microscopy, and scanning electron microscopy. In-vivo biodistribution and tumor avidity studies were performed by intravenously injecting of cysteamine@198AuNPs: CdTe QDs nanocomposite into rats. The %ID/g (percent of the initial dose per gram tissue weight) in dissected organs and Fibrosarcoma tumor specimens was then measured. The hydrophilicity of the cysteamine@198AuNPs was increased by surface modification with CdTe QDs. Rapid excretion from body and high tumor uptake for cysteamine@198AuNPs: CdTe QDs revealed that this radiotracer could potentially be used in nuclear medicine as a theranostic agent.

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Exploring Feasibility of Multicolored CdTe Quantum Dots for In Vitro and In Vivo Fluorescent Imaging

Journal of Nanoscience and Nanotechnology ◽

10.1166/jnn.2008.18167 ◽

2008 ◽

Vol 8 (3) ◽

pp. 1174-1177 ◽

Cited By ~ 19

Author(s):

Junfeng Su ◽

Jun Zhang ◽

Li Liu ◽

Yalou Huang ◽

Ralph P. Mason

Keyword(s):

Quantum Dots ◽

Fluorescence Imaging ◽

Water Solubility ◽

Imaging System ◽

Fluorescent Imaging ◽

Cdte Quantum Dots ◽

Cdte Qds ◽

Fluorescence Imaging System

We report the use of novel multicolored CdTe quantum dots (QDs) as fluorophores for biological fluorescence imaging. The CdTe QDs were prepared to exhibit emission wavelengths in the green, yellow, and red range by using trifluoroacetic acid (TFA), L-cysteine and thioglycolic acid (TGA) as surface stabilizers, respectively. The particles have good water solubility and photostability. Fluorescence imaging potential was evaluated in vitro and in vivo using a multispectral Maestro CRI Fluorescence Imaging system. The results show that different colored CdTe QDs allow sensitive detection simultaneously or separately both in vitro and in vivo against background fluorescence. The studies indicate that CdTe QDs can provide alternative fluorescent probes for biological imaging.

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Electrostatic repulsion strategy for highly selective and sensitive “switch–on” fluorescence sensor of ascorbic acid based on the cysteamine-coated CdTe quantum dots and cerium (IV)

New Journal of Chemistry ◽

10.1039/d1nj00145k ◽

2021 ◽

Author(s):

Yifei Guo ◽

Jingjing Du ◽

Jianjun Li ◽

Ran Yang ◽

Peter B. de Harrington ◽

...

Keyword(s):

Quantum Dots ◽

Ascorbic Acid ◽

Hydrothermal Method ◽

Cadmium Chloride ◽

Fluorescence Sensor ◽

Cdte Quantum Dots ◽

Electrostatic Repulsion ◽

Functional Monomer ◽

Simple Hydrothermal Method ◽

Cdte Qds

In this work, cysteamine-coated CdTe quantum dots (CA-CdTe QDs) were synthesized by a simple hydrothermal method employing cadmium chloride as the cadmium source and cysteamine hydrochloride as the functional monomer....

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A simple paper-based approach for arsenic determination in water using hydride generation coupled with mercaptosuccinic-acid capped CdTe quantum dots

Analytical Methods ◽

10.1039/d0ay00273a ◽

2020 ◽

Vol 12 (21) ◽

pp. 2718-2726

Author(s):

Oraphan Thepmanee ◽

Kanlaya Prapainop ◽

Obnithi Noppha ◽

Nuanlaor Rattanawimanwong ◽

Weena Siangproh ◽

...

Keyword(s):

Quantum Dots ◽

Hydride Generation ◽

Cdte Quantum Dots ◽

Mercaptosuccinic Acid ◽

Cdte Qds ◽

Arsenic Detection ◽

Detection Probe ◽

Arsenic Determination

Paper-based device with MSA-CdTe QDs as arsenic detection probe is presented.

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Quantum Dots; Synthesis, Application, Toxicology and Surface Modification with Special Consideration on CdTe QDs

10.2174/9789815036817121010005 ◽

2021 ◽

pp. 21-43

Keyword(s):

Quantum Dots ◽

Surface Modification ◽

Special Consideration ◽

Cdte Qds

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Silver ion-doped CdTe quantum dots as fluorescent probe for Hg2+ detection

RSC Advances ◽

10.1039/d0ra07140d ◽

2020 ◽

Vol 10 (64) ◽

pp. 38965-38973

Author(s):

Huazheng Li ◽

Wangwei Lu ◽

Gaoling Zhao ◽

Bin Song ◽

Jing Zhou ◽

...

Keyword(s):

Quantum Dots ◽

Fluorescent Probe ◽

Fluorescence Intensity ◽

Silver Ion ◽

Cdte Quantum Dots ◽

Detection Range ◽

Cdte Qds ◽

Linear Relationships ◽

The Relationship

Ag-doped CdTe QDs emit multiple-fluorescence peaks, and the relationship between fluorescence intensity and the concentration of Hg2+ is established. Two linear relationships are obtained, which is benefit to the extension of detection range.

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Fluorescence suppression of MPA stabilized CdTe QDs for direct determination of propranolol

Analytical Methods ◽

10.1039/c6ay02711c ◽

2017 ◽

Vol 9 (6) ◽

pp. 929-936 ◽

Cited By ~ 4

Author(s):

Fan Zhang ◽

Miaomiao Chen ◽

Haiqing Zhang ◽

Huayu Xiong ◽

Wei Wen ◽

...

Keyword(s):

Quantum Dots ◽

Fluorescent Sensor ◽

Direct Determination ◽

Cdte Quantum Dots ◽

Mercaptopropionic Acid ◽

Cdte Qds

A sensitive, convenient and rapid fluorescent sensor for effectively and directly detecting propranolol was proposed based on the fluorescence suppression of 3-mercaptopropionic acid stabilized CdTe quantum dots.

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Synthesis of CdSe/ZnS and CdTe/ZnS Quantum Dots: Refined Digestive Ripening

Journal of Nanomaterials ◽

10.1155/2012/312087 ◽

2012 ◽

Vol 2012 ◽

pp. 1-12 ◽

Cited By ~ 16

Author(s):

Sreeram Cingarapu ◽

Zhiqiang Yang ◽

Christopher M. Sorensen ◽

Kenneth J. Klabunde

Keyword(s):

Electron Microscopy ◽

Transmission Electron Microscopy ◽

Quantum Dots ◽

Scale Up ◽

Trioctylphosphine Oxide ◽

Cdse Qds ◽

Selective Precipitation ◽

Digestive Ripening ◽

Cdte Qds ◽

Transmission Electron

We report synthesis of CdSe and CdTe quantum dots (QDs) from the bulk CdSe and CdTe material by evaporation/co-condensation using the solvated metal atom dispersion (SMAD) technique and refined digestive ripening. The outcomes of this new process are (1) the reduction of digestive ripening time by employing ligands (trioctylphosphine oxide (TOPO) and oleylamine (OA)) as capping agent as well as digestive ripening solvent, (2) ability to tune the photoluminescence (PL) from 410 nm to 670 nm, (3) demonstrate the ability of SMAD synthesis technique for other semiconductors (CdTe), (4) direct comparison of CdSe QDs growth with CdTe QDs growth based on digestive ripening times, and (5) enhanced PL quantum yield (QY) of CdSe QDs and CdTe QDs upon covering with a ZnS shell. Further, the merit of this synthesis is the use of bulk CdSe and CdTe as the starting materials, which avoids usage of toxic organometallic compounds, eliminates the hot injection procedure, and size selective precipitation processes. It also allows the possibility of scale up. These QDs were characterized by UV-vis, photoluminescence (PL), transmission electron microscopy (TEM), high-resolution transmission electron microscopy (HRTEM), X-ray photoelectron spectroscopy (XPS), and powder XRD.

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