scholarly journals Successfully treated multiple brain abscess in a newborn: a case report

2017 ◽  
Vol 31 (2) ◽  
pp. 172-177
Author(s):  
Aleksic Vuk ◽  
Mihajlovic Miljan ◽  
Zivković Nenad ◽  
Misela Raus ◽  
Marko Samardzic ◽  
...  
Keyword(s):  
Case Report ◽  
Antibiotic Therapy ◽  
Brain Abscess ◽  
Ventriculoperitoneal Shunt ◽  
Combined Therapy ◽  
Late Complication ◽  
Primary Source ◽  
Medical Problem ◽  
High Morbidity ◽  
Brain Abscesses

Abstract Multiple brain abscesses are exceedingly uncommon in newborns and represent a serious medical problem associated with high morbidity and mortality. Treatment is also controversial issue, and can require surgery, abscess aspiration, antibiotic therapy, and eradication of the primary source. We report a case of successfully treated multiple brain abscess in a newborn with combined therapy which consisted of abscess aspiration and prolonged antibiotics. Patient developed hydrocephalus as late complication which was also successfully treated with ventriculoperitoneal shunt.

scholarly journals Brain Abscess Caused by Nocardia: Case Report and Literature Review

2020 ◽  
Author(s):  
Guilherme Finger ◽  
Maria Eduarda Conte Gripa ◽  
Tiago Paczko Bozko Cecchini ◽  
Tobias Ludwig do Nascimento
Keyword(s):  
Case Report ◽  
Antibiotic Therapy ◽  
Brain Abscess ◽  
Clinical Signs ◽  
Occipital Lobe ◽  
High Morbidity ◽  
Rare Clinical Entity ◽  
Brain Abscesses

AbstractNocardia brain abscess is a rare clinical entity, accounting for 2% of all brain abscesses, associated with high morbidity and a mortality rate 3 times higher than brain abscesses caused by other bacteria. Proper investigation and treatment, characterized by a long-term antibiotic therapy, play an important role on the outcome of the patient. The authors describe a case of a patient without neurological comorbidities who developed clinical signs of right occipital lobe impairment and seizures, whose investigation demonstrated brain abscess caused by Nocardia spp. The patient was treated surgically followed by antibiotic therapy with a great outcome after 1 year of follow-up.

scholarly journals Parvimonas micra: A potential causative pathogen to consider when diagnosing odontogenic brain abscesses

2020 ◽  
Vol 11 ◽  
pp. 140
Author(s):  
Ruth Prieto ◽  
Alejandro Callejas-Díaz ◽  
Rasha Hassan ◽  
Alberto Pérez de Vargas ◽  
Luis Fernando López-Pájaro
Keyword(s):  
Antibiotic Therapy ◽  
Brain Abscess ◽  
Primary Source ◽  
16S Rrna Gene Sequencing ◽  
Rrna Gene ◽  
Sequencing Analysis ◽  
Surgical Drainage ◽  
Source Of Infection ◽  
Parvimonas Micra ◽  
Brain Abscesses

Background: Brain abscess is a life-threatening entity which requires prompt and long-term antibiotic therapy, generally associated with surgical drainage, and eradicating the primary source of infection. Parvimonas micra (Pm) has only been reported once before as the lone infecting organism of an orally originated, solitary brain abscess. Diagnosing brain abscesses caused by this Gram-positive anaerobic coccus, constituent of the oral cavity flora, is challenging, and an optimal treatment regimen has not been well established. We report the diagnosis and successful treatment of a Pm caused odontogenic brain abscess. Case Description: A 62-year-old immunocompetent male with a right-parietal brain abscess presented with headache and seizures. He was started on empirical antibiotic therapy and subsequently underwent surgical drainage. The only source of infection found was severe periodontitis with infected mandibular cysts. Thus, tooth extraction and cyst curettage were performed 1 week after brain surgery. Cultures of brain abscess fluid were negative, but amplification of bacterial 16S ribosomal RNA (rRNA) with polymerase chain reaction demonstrated Pm. After 3 weeks of intravenous ceftriaxone and metronidazole, the patient was switched to oral metronidazole and moxifloxacin for 6 weeks. Conclusions: This case highlights the potential risk of untreated dental infections causing brain abscesses. Pm should be considered as a possible pathogen of odontogenic brain abscesses despite its presence usually not being detected by standard bacterial cultures. Therefore, 16S rRNA gene sequencing analysis is strongly recommended for bacterial identification before defining brain abscesses as cryptogenic.

scholarly journals Pyogenic brain abscess caused by Serratia marcescens in a Brazilian premature neonate

2018 ◽  
Vol 23 (1) ◽  
pp. 65-68
Author(s):  
Regina Célia Ajeje Pires De Albuquerque ◽  
Lilian Beani ◽  
Raquel Siqueira Leonel De Paula ◽  
Lucas Crociati Meguins
Keyword(s):  
Antibiotic Therapy ◽  
Serratia Marcescens ◽  
Brain Abscess ◽  
Present Report ◽  
Pediatric Population ◽  
Primary Source ◽  
Premature Neonate ◽  
Diagnostic Measures ◽  
Microbiological Techniques ◽  
Brain Abscesses

Bacterial brain abscess remain a serious central nervous system infectious disorder despite advances in neurosurgical, neuroimaging, clinical support on intensive care units, microbiological techniques and availability of new antibiotics. The successful treatment of brain abscess usually requires surgery, appropriate antibiotic therapy and eradication of the primary source. Although uncommon, brain abscesses are particularly important in the pediatric population due to its devastating potential to cause severe neurologic deficits, especially in preterm newborns. The purpose of the present report is to describe the case of a Brazilian premature neonate with pyogenic brain abscesses caused by Serratia marcescens and to discuss therapeutic and diagnostic approaches. The early suspicion, proper diagnostic measures and immediate neurosurgical consultation associated with aggressive antibiotic therapy seem to be the essentials steps on themanagement for those high-risk pediatric patients.

scholarly journals Brainstem abscess of undetermined origin: microsurgical drainage and brief antibiotic therapy

2014 ◽  
Vol 132 (2) ◽  
pp. 121-124 ◽  
Author(s):  
Pedro Tadao Hamamoto Filho ◽  
Marco Antonio Zanini
Keyword(s):  
Case Report ◽  
Antibiotic Therapy ◽  
Postoperative Recovery ◽  
High Morbidity ◽  
Stereotactic Aspiration ◽  
Systemic Antibiotic ◽  
Systemic Antibiotic Therapy ◽  
Microsurgical Approach ◽  
Surgical Options ◽  
Systemic Infections

CONTEXT: Solitary brainstem abscesses are rare and they are usually associated with other infections. They are severe conditions with high morbidity and mortality. The surgical options are stereotactic aspiration and microsurgical drainage. Systemic antibiotic therapy is used for more than six weeks. CASE REPORT: We present the case of a young man with a solitary abscess at the pons, without other systemic infections. The patient was treated by means of microsurgical drainage and antibiotic therapy for three weeks. His postoperative recovery was good. CONCLUSIONS: A microsurgical approach may be considered to be an important option for large abscesses that are multiloculated, close to the surface or contain thick fluid. Complete emptying of the purulent accumulation may diminish the required duration of antibiotic therapy.

scholarly journals A case of odontogenic brain abscess arising from covert dental sepsis

2012 ◽  
Vol 94 (1) ◽  
pp. e41-e43 ◽  
Author(s):  
TC Clifton ◽  
S Kalamchi
Keyword(s):  
Case Report ◽  
Brain Abscess ◽  
Dental Treatment ◽  
The Body ◽  
Tooth Decay ◽  
Odontogenic Infections ◽  
Life Threatening ◽  
Brain Abscesses ◽  
Dental Infections

Odontogenic infections can spread to any organ of the body and in some cases cause life threatening infections. We report a case of multiple odontogenic brain abscesses resulting from undetected tooth decay. Whereas most odontogenic brain abscesses occur following dental treatment, this report documents brain abscesses prior to dental treatment, signifying the dangers of covert dental infections. This case report updates the literature on the topic of odontogenic brain abscesses.

scholarly journals Mycobacterium Avium Complex Infection as a Rare Cause of Cerebral Mass Lesion and IRIS in a Patient with AIDS: Case Report and Review of the Literature

2021 ◽  
Author(s):  
Courtney Lane-Donovan ◽  
Emma Bainbridge ◽  
John Szumowski ◽  
Andrew D Kerkhoff ◽  
Michael J Peluso
Keyword(s):  
Case Report ◽  
Brain Abscess ◽  
Mycobacterium Avium ◽  
Diagnostic Tool ◽  
Mycobacterium Avium Complex ◽  
Brain Biopsy ◽  
Mass Lesion ◽  
Review Of The Literature ◽  
Clinicopathologic Characteristics ◽  
Brain Abscesses

Abstract A patient with advanced HIV/AIDS presented with a brain abscess. While brain biopsy culture and pathology were unrevealing, universal broad-range PCR (uPCR) demonstrated Mycobacterium avium complex (MAC). We review the clinicopathologic characteristics of MAC brain abscesses and highlight the effectiveness of uPCR as a diagnostic tool in partially-treated infections.

scholarly journals Cerebral Abscess with Cranial Hypertension in Young Infants: A Case Report and Systematic Review

2021 ◽  
Vol 2 (4) ◽  
Author(s):  
Náthalie Angélica Cardoso Marqui ◽  
Marina Lucca de Campos Lima ◽  
Rafaela de Fátima Ferreira Baptista ◽  
Rawene Elza Veronesi Gonçalves Righetti ◽  
Tauane Rene Martins ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Antibiotic Therapy ◽  
Brain Abscess ◽  
Broad Spectrum ◽  
Central Nervous System Infection ◽  
Mass Effect ◽  
Morbidity And Mortality ◽  
High Morbidity ◽  
Surgical Drainage ◽  
Young Infants

Objective: To report a Central Nervous System infection evolving with brain abscess and to address aspects of the treatment of the disease. Results: even with advances in treatment and diagnosis, the pathology has a high mortality. However, the best prognosis is noticed when there is a suspicion through the clinic, neuroradiological images readily available, antimicrobial therapy against commonly encountered agents, and surgical drainage procedures. One study, which combined antibiotic therapy and surgery to drain the abscess, in most of the cases, studied, demonstrated a mortality rate of 12%, and another study, a 42% mortality rate when using antibiotic therapy alone. Another reference suggests the use of antibiotic therapy alone in less severe cases with less neurological impairment. Neurological clinical sequelae can be found in up to 30% of cases. The time of antibiotic therapy still needs to be debated, as well as the surgical indication for drainage. Final Considerations: Pediatric brain abscess is an uncommon disease, still with high morbidity and mortality. Surgical drainage or excision of pediatric abscesses remains the basis of treatment both to relieve the mass effect and to provide a microbiological diagnosis. The literature demonstrates that broad-spectrum antibiotics and access to CT and MRI images decrease the rates of morbidity and mortality. It is concluded that the therapeutic approach involves the administration of broad-spectrum intravenous antibiotics and surgical drainage in more complex cases.

scholarly journals Management of Intracranial Abscess - Study of 30 cases

1970 ◽  
Vol 16 (2) ◽  
pp. 73-75
Author(s):  
Md L Rahman ◽  
ML Rahman ◽  
S Hossain ◽  
ASMS Ali ◽  
SK Pramanik ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Antibiotic Therapy ◽  
Brain Abscess ◽  
Diagnostic Tools ◽  
Intracranial Abscess ◽  
Multiple Abscess ◽  
Brain Abscesses ◽  
Burr Hole Evacuation ◽  
Made In

Brain abscess may be solitary or multiple. They appear as areas of ill-defined cerebritis tomature well defined focal suppurative lesion with capsulated abscesses. Multiple brain abscessrecognized in as many as 50% of patients. In this study 30 patients were analyzed. Solitary brainabscess were more than multiple abscess. Age ranges from 6 years to 35 years. Male to femaleratio was 5:1. Intra parenchymal brain abscess occurred in all cases (100%), subdural orextradural lesions were nil. Brain abscesses were associated with CSOM. CT scan done in all(100%) patients as diagnostic tools. All (100%) patients under went Burr-hole evacuation withbroad-spectrum antibiotic therapy and 2 patients (06.66%) treated with long term anti tuberculartherapy. V-P shunt was made in 1 patient (03.33%) who had persistent venriculomegaly. In thisstudy mortality rate was zero.doi: 10.3329/taj.v16i2.3887TAJ December 2003; Vol.16(2): 73-75

scholarly journals From dental infection to extradural empyema: a case report

2019 ◽  
Vol 25 (2) ◽  
pp. 20
Author(s):  
Clément Comte ◽  
Nasr Hasnaoui
Keyword(s):  
Case Report ◽  
Antibiotic Therapy ◽  
Ct Scan ◽  
Brain Abscess ◽  
Systematic Investigation ◽  
Subdural Empyema ◽  
Dental Infection ◽  
Dental Origin ◽  
Eye Infection

Introduction: Brain infections of dental origin are rare, but well-known and accurately described. There are two different brain infections: brain abscess, the most frequent, and extradural or subdural empyema. Here, we discuss the case of an extradural empyema. Observation: A 28-year-old man with a very poor dental condition showed neurological and eye infection signs. A brain and face CT scan revealed extradural empyema, orbit abscess and pansinusitis. These infections had all dental origin: an apical lesion of tooth 26. Discussion: Such severe cases must be surgically and medically treated with a strong antibiotic therapy. A systematic investigation and the treatment of dental infected areas are both necessary.

scholarly journals Multiple brain abscesses: A case report

2004 ◽  
Vol 57 (9-10) ◽  
pp. 498-500
Author(s):  
Sofija Banic-Horvat ◽  
Milan Cvijanovic ◽  
Miroslav Ilin ◽  
Aleksandar Kopitovic ◽  
Svetlana Simic ◽  
...  
Keyword(s):  
Case Report ◽  
Brain Abscess ◽  
Brain Mri ◽  
Diagnostic Procedures ◽  
X Ray ◽  
General Weakness ◽  
Infection Source ◽  
Chest X Ray ◽  
Brain Abscesses ◽  
High Doses

Case Report 10 days before admission a 45-year old female experienced general weakness, and T 38oC. During that period she had no cardio-respiratory nor neurological complaints, and the temperature varied between 37.5oC and 38oC. Her medical history was unremarkable, without immunodeficiency. The day before admission she presented with left arm paresis and during the next day it progressed to paralysis. She had no headache. On admission the following diagnostic procedures were performed: the cranial CT scan showed two lesions (possibly meta lesions). Chest X-ray was normal. WBC=15x109/L, ESR= 90/120. On the second day following admission brain MRI showed multiple abscesses in both hemispheres, mostly in the gray/white junction. High doses of IV metronidasol, cephtriaxon and cipfloxacin were administered without obtaining specimens for micro- biological diagnosis. In next two days she developed coma, respiratory insufficiency and septic temperature. Brain surgery was not performed due to severe involvement of the brain with multiple abscesses. Repeated chest X-ray revealed bilateral pneumonia. A lethal outcome occurred on the third day, regardless of all efforts. Autopsy showed multiple brain abscesses as well as on the lungs and liver. A beta-hemolytic streptococcal infection was established. Conclusions Prevention includes treatment of the infection source. The classic triad of headache, fever and focal deficit occur in less than 50% of patients. Even in such cases brain abscess must be reconsidered. CT appearance of brain abscess is similar to that of neoplastic and other infectious and non infectious deseases - especially in the stage of early cerebritis. If the CT findings are not clear, MRI should be performed.

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