Research for the lichen Usnea barbata metabolites

2018 ◽  
Vol 73 (7-8) ◽  
pp. 291-296 ◽  
Author(s):  
Yulia Bazarnova ◽  
Natalia Politaeva ◽  
Nadegda Lyskova
Keyword(s):  
Antioxidant Activity ◽  
Antimicrobial Properties ◽  
Usnic Acid ◽  
Analytical Techniques ◽  
Biologically Active ◽  
Active Metabolites ◽  
Dry Extract ◽  
Solvent Systems ◽  
Biologically Active Metabolites ◽  
Modern Analytical

AbstractThis work presents investigations of biologically active metabolites ofUsnea barbatalichen. Extraction conditions for usnic acid and other biologically active phytocomponents using various solvent systems were chosen. Modern analytical techniques were used to study composition of the obtained extracts; usnic acid and phenolic compound contents were estimated. Antioxidant activity and antimicrobial properties of lichen dry extract against bacteriaBacillus subtilisandPseudomonas fluorescenswere studied.

scholarly journals STUDY OF THE COMPOSITION AND PROPERTIES OF SECONDARY METABOLITES OF THE LICHEN USNEA BARBATA

2017 ◽  
pp. 121-127
Author(s):  
Надежда (Nadezhda) Сергеевна (Sergeevna) Лыскова (Lyskova) ◽  
Юлия (Iuliia) Генриховна (Genrikhovna) Базарнова (Bazarnova) ◽  
Игорь (Igor') Вадимович (Vadimovic) Кручина-Богданов (Kruchina-Bogdanov )
Keyword(s):  
Secondary Metabolites ◽  
Visible Region ◽  
Antimicrobial Properties ◽  
Usnic Acid ◽  
Modern Society ◽  
Biologically Active ◽  
Active Metabolites ◽  
Dry Extract ◽  
Lichen Metabolites ◽  
Biologically Active Metabolites

In the modern society value of many biological resources remains underestimated. Lichens are one of the unique poorly studied bioresources. These are amazing organisms, formed by symbiosis of algae and fungus. Due to this combination, lichens have a number of unique properties.In this article the results of study the composition of biologically active secondary lichen metabolites of the Usnea barbata lichen. Antioxidant activity and antimicrobial properties of dry lichen extract against bacteria Bac. Subtilis. The conditions for extraction of biologically active metabolites using solvent systems such as water, water-ethanol mixtures with ethanol content of 40 and 70%, 1,4-dioxane and a mixture of 1,4-dioxane and water (1: 1) were selected. With use of the modern analytical methods, the composition of secondary metabolites in the extracts was studied. By the method of spectroscopy in the UV and visible region of the spectrum to determine the content usnic acid, which is 16,2 (solvent - water) to 60,0 (1,4-dioxane) mg/100 ml of extract.It is shown that the dioxane extract has pronounced atioxidant properties. The active substances (in terms of usnic acid) of the dry extract of lichen Usnea barbata are able to inhibit the growth of bacteria Bac. Subtilis.

scholarly journals Distribution of mycotoxins in cyanolichens on the coast of the White Sea

2020 ◽  
Vol 10 (2) ◽  
pp. 170-184
Author(s):  
Tatiana Yu. Tolpysheva
Keyword(s):  
Acid Content ◽  
White Sea ◽  
Usnic Acid ◽  
Reliable Data ◽  
Biologically Active ◽  
Enzyme Linked Immunosorbent Assay ◽  
Qualitative Composition ◽  
The White Sea ◽  
Active Metabolites ◽  
Biologically Active Metabolites

In the lichen thalli of 6 Peltigera species and Nephroma arcticum enzyme-linked immunosorbent assay was conducted to investigate the distribution of low-molecular biologically active metabolites related to the group of mycotoxins, as well as the distribution of usnic acid at N. arcticum. Thirteen of micotoxins have been founds in the lichens. Qualitative composition of mycotoxins varies in different species of Peltigera and P. aphthosa, collected in different years. Some mycotoxins showed statistically significant differences of their content in theand lower parts of the thalli of 4 Peltigera species and Nephroma arcticum. The trend of higher accumulation of mycotoxins in the lower older part of the thalli as compared with the younger ones was noted. Statistically reliable data on the higher usnic acid content in the younger of the thallus of N. arcticum as compared with the older was obtained.

Spices with Breast Cancer Chemopreventive and Therapeutic Potentials: A Functional Foods Based-Review

2018 ◽  
Vol 18 (2) ◽  
pp. 182-194 ◽  
Author(s):  
Aliyu Muhammad ◽  
Mohammed Auwal Ibrahim ◽  
Ochuko Lucky Erukainure ◽  
Ibrahim Malami ◽  
Auwal Adamu
Keyword(s):  
Breast Cancer ◽  
Urban Areas ◽  
Cancer Chemoprevention ◽  
Biologically Active ◽  
Active Metabolites ◽  
Rural And Urban Areas ◽  
Anticancer Properties ◽  
Rural And Urban ◽  
Breast Cancer Chemoprevention ◽  
Biologically Active Metabolites

Background: Cancer is a multifaceted metabolic disease that affects sizeable dwellers of rural and urban areas. Among the various types of cancer, mammary cancer is one of the most frequently diagnosed cancers in women. Its menace can be curbed with locally consumed spices due to their multiple bioactive phytochemicals. Aims: This review focuses on the breast cancer chemopreventive and therapeutic potentials of locally consumed spices. Methods/Results: The most commonly consumed spices with breast cancer chemopreventive and chemotherapeutic phytochemical include pepper, onions, ginger, garlic, curry and thyme containing many biologically active metabolites ranging from vitamins, fatty acids esters, polyphenols/phenolics, sulfurcontaining compounds and anthraquinones with proven antioxidant, anti-inflammatory, immuno-modulatory, antitumor and anticancer properties against breast cancer/carcinogenesis. Therefore, extracts and active principles of these spices could be explored in breast cancer chemoprevention and possibly therapeutically which may provide an avenue for reducing the risk and prevalence of breast cancer.

ChemInform Abstract: Biologically Active Metabolites of the Actinobacterium Streptomyces sp. GW 33/1593.

ChemInform ◽  
2009 ◽  
Vol 40 (30) ◽  
Author(s):  
M. P. Sobolevskaya ◽  
V. A. Denisenko ◽  
S. Fotso ◽  
H. Laach ◽  
N. I. Menzorova ◽  
...  
Keyword(s):  
Biologically Active ◽  
Active Metabolites ◽  
Streptomyces Sp ◽  
Biologically Active Metabolites

Biologically Active Metabolites from Marine Organisms

1995 ◽  
Vol 42 (4) ◽  
pp. 735-738 ◽  
Author(s):  
Jingyu Su ◽  
Longmei Zeng ◽  
Yongli Zhong ◽  
Xiong Fu
Keyword(s):  
Marine Organisms ◽  
Biologically Active ◽  
Active Metabolites ◽  
Biologically Active Metabolites

The chemistry of fungal antagonism and defense

1995 ◽  
Vol 73 (S1) ◽  
pp. 1265-1274 ◽  
Author(s):  
James B. Gloer
Keyword(s):  
Interdisciplinary Studies ◽  
Biologically Active ◽  
Model Systems ◽  
Fungal Metabolites ◽  
Ecological Studies ◽  
Active Metabolites ◽  
Broad Array ◽  
Fungal Antagonism ◽  
Antifungal Chemotherapy ◽  
Biologically Active Metabolites

Mechanisms of fungal antagonism and defense often include the production of biologically active metabolites by one species that exert effects on potential competitors and (or) predators. Studies carried out in our laboratory and others clearly indicate that such ecological phenomena can serve as valuable leads to the discovery of novel and potentially useful bioactive fungal metabolites. There is evidence that some of these compounds may render advantages to the producing organism, although careful and definitive ecological studies are required to determine this. Nevertheless, the results summarized here demonstrate the broad array of possible benefits that can arise from interdisciplinary studies in this area. This paper focuses primarily on our own investigations of the chemistry involved in fungal antagonism and defense using coprophilous and sclerotial fungi as model systems. These results have potential implications in many areas of study, including fungal ecology, secondary metabolism, chemotaxonomy, organic chemistry, structure determination, antifungal chemotherapy, and insect control. Key words: fungi, antifungal, insecticide, antagonism, chemical defense, secondary metabolites.

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