scholarly journals STUDY OF THE COMPOSITION AND PROPERTIES OF SECONDARY METABOLITES OF THE LICHEN USNEA BARBATA

2017 ◽  
pp. 121-127
Author(s):  
Надежда (Nadezhda) Сергеевна (Sergeevna) Лыскова (Lyskova) ◽  
Юлия (Iuliia) Генриховна (Genrikhovna) Базарнова (Bazarnova) ◽  
Игорь (Igor') Вадимович (Vadimovic) Кручина-Богданов (Kruchina-Bogdanov )
Keyword(s):  
Secondary Metabolites ◽  
Visible Region ◽  
Antimicrobial Properties ◽  
Usnic Acid ◽  
Modern Society ◽  
Biologically Active ◽  
Active Metabolites ◽  
Dry Extract ◽  
Lichen Metabolites ◽  
Biologically Active Metabolites

In the modern society value of many biological resources remains underestimated. Lichens are one of the unique poorly studied bioresources. These are amazing organisms, formed by symbiosis of algae and fungus. Due to this combination, lichens have a number of unique properties.In this article the results of study the composition of biologically active secondary lichen metabolites of the Usnea barbata lichen. Antioxidant activity and antimicrobial properties of dry lichen extract against bacteria Bac. Subtilis. The conditions for extraction of biologically active metabolites using solvent systems such as water, water-ethanol mixtures with ethanol content of 40 and 70%, 1,4-dioxane and a mixture of 1,4-dioxane and water (1: 1) were selected. With use of the modern analytical methods, the composition of secondary metabolites in the extracts was studied. By the method of spectroscopy in the UV and visible region of the spectrum to determine the content usnic acid, which is 16,2 (solvent - water) to 60,0 (1,4-dioxane) mg/100 ml of extract.It is shown that the dioxane extract has pronounced atioxidant properties. The active substances (in terms of usnic acid) of the dry extract of lichen Usnea barbata are able to inhibit the growth of bacteria Bac. Subtilis.

Research for the lichen Usnea barbata metabolites

2018 ◽  
Vol 73 (7-8) ◽  
pp. 291-296 ◽  
Author(s):  
Yulia Bazarnova ◽  
Natalia Politaeva ◽  
Nadegda Lyskova
Keyword(s):  
Antioxidant Activity ◽  
Antimicrobial Properties ◽  
Usnic Acid ◽  
Analytical Techniques ◽  
Biologically Active ◽  
Active Metabolites ◽  
Dry Extract ◽  
Solvent Systems ◽  
Biologically Active Metabolites ◽  
Modern Analytical

AbstractThis work presents investigations of biologically active metabolites ofUsnea barbatalichen. Extraction conditions for usnic acid and other biologically active phytocomponents using various solvent systems were chosen. Modern analytical techniques were used to study composition of the obtained extracts; usnic acid and phenolic compound contents were estimated. Antioxidant activity and antimicrobial properties of lichen dry extract against bacteriaBacillus subtilisandPseudomonas fluorescenswere studied.

scholarly journals Marine-derived myxobacteria of the suborder Nannocystineae: An underexplored source of structurally intriguing and biologically active metabolites

2016 ◽  
Vol 12 ◽  
pp. 969-984 ◽  
Author(s):  
Antonio Dávila-Céspedes ◽  
Peter Hufendiek ◽  
Max Crüsemann ◽  
Till F Schäberle ◽  
Gabriele M König
Keyword(s):  
Secondary Metabolites ◽  
In Silico ◽  
Structural Type ◽  
Biologically Active ◽  
Active Metabolites ◽  
Genome Sequences ◽  
Structural Types ◽  
Biologically Active Metabolites ◽  
In Silico Analyses

Myxobacteria are famous for their ability to produce most intriguing secondary metabolites. Till recently, only terrestrial myxobacteria were in the focus of research. In this review, however, we discuss marine-derived myxobacteria, which are particularly interesting due to their relatively recent discovery and due to the fact that their very existence was called into question. The to-date-explored members of these halophilic or halotolerant myxobacteria are all grouped into the suborder Nannocystineae. Few of them were chemically investigated revealing around 11 structural types belonging to the polyketide, non-ribosomal peptide, hybrids thereof or terpenoid class of secondary metabolites. A most unusual structural type is represented by salimabromide fromEnhygromyxa salina. In silico analyses were carried out on the available genome sequences of four bacterial members of the Nannocystineae, revealing the biosynthetic potential of these bacteria.

scholarly journals Distribution of mycotoxins in cyanolichens on the coast of the White Sea

2020 ◽  
Vol 10 (2) ◽  
pp. 170-184
Author(s):  
Tatiana Yu. Tolpysheva
Keyword(s):  
Acid Content ◽  
White Sea ◽  
Usnic Acid ◽  
Reliable Data ◽  
Biologically Active ◽  
Enzyme Linked Immunosorbent Assay ◽  
Qualitative Composition ◽  
The White Sea ◽  
Active Metabolites ◽  
Biologically Active Metabolites

In the lichen thalli of 6 Peltigera species and Nephroma arcticum enzyme-linked immunosorbent assay was conducted to investigate the distribution of low-molecular biologically active metabolites related to the group of mycotoxins, as well as the distribution of usnic acid at N. arcticum. Thirteen of micotoxins have been founds in the lichens. Qualitative composition of mycotoxins varies in different species of Peltigera and P. aphthosa, collected in different years. Some mycotoxins showed statistically significant differences of their content in theand lower parts of the thalli of 4 Peltigera species and Nephroma arcticum. The trend of higher accumulation of mycotoxins in the lower older part of the thalli as compared with the younger ones was noted. Statistically reliable data on the higher usnic acid content in the younger of the thallus of N. arcticum as compared with the older was obtained.

scholarly journals Secondary Metabolites of Purpureocilliumlilacinum

Molecules ◽  
2021 ◽  
Vol 27 (1) ◽  
pp. 18
Author(s):  
Wei Chen ◽  
Qiongbo Hu
Keyword(s):  
Secondary Metabolites ◽  
Biological Activities ◽  
Chemical Diversity ◽  
Biologically Active ◽  
Parasitic Nematodes ◽  
Active Metabolites ◽  
Comprehensive Overview ◽  
Lead Compounds ◽  
Purpureocillium Lilacinum ◽  
Biologically Active Metabolites

Fungi can synthesize a wealth of secondary metabolites, which are widely used in the exploration of lead compounds of pharmaceutical or agricultural importance. Beauveria, Metarhizium, and Cordyceps are the most extensively studied fungi in which a large number of biologically active metabolites have been identified. However, relatively little attention has been paid to Purpureocillium lilacinum. P. lilacinum are soil-habituated fungi that are widely distributed in nature and are very important biocontrol fungi in agriculture, providing good biological control of plant parasitic nematodes and having a significant effect on Aphidoidea, Tetranychus cinnbarinus, and Aleyrodidae. At the same time, it produces secondary metabolites with various biological activities such as anticancer, antimicrobial, and insecticidal. This review attempts to provide a comprehensive overview of the secondary metabolites of P. lilacinum, with emphasis on the chemical diversity and biological activity of these secondary metabolites and the biosynthetic pathways, and gives new insight into the secondary metabolites of medical and entomogenous fungi, which is expected to provide a reference for the development of medicine and agrochemicals in the future.

Spices with Breast Cancer Chemopreventive and Therapeutic Potentials: A Functional Foods Based-Review

2018 ◽  
Vol 18 (2) ◽  
pp. 182-194 ◽  
Author(s):  
Aliyu Muhammad ◽  
Mohammed Auwal Ibrahim ◽  
Ochuko Lucky Erukainure ◽  
Ibrahim Malami ◽  
Auwal Adamu
Keyword(s):  
Breast Cancer ◽  
Urban Areas ◽  
Cancer Chemoprevention ◽  
Biologically Active ◽  
Active Metabolites ◽  
Rural And Urban Areas ◽  
Anticancer Properties ◽  
Rural And Urban ◽  
Breast Cancer Chemoprevention ◽  
Biologically Active Metabolites

Background: Cancer is a multifaceted metabolic disease that affects sizeable dwellers of rural and urban areas. Among the various types of cancer, mammary cancer is one of the most frequently diagnosed cancers in women. Its menace can be curbed with locally consumed spices due to their multiple bioactive phytochemicals. Aims: This review focuses on the breast cancer chemopreventive and therapeutic potentials of locally consumed spices. Methods/Results: The most commonly consumed spices with breast cancer chemopreventive and chemotherapeutic phytochemical include pepper, onions, ginger, garlic, curry and thyme containing many biologically active metabolites ranging from vitamins, fatty acids esters, polyphenols/phenolics, sulfurcontaining compounds and anthraquinones with proven antioxidant, anti-inflammatory, immuno-modulatory, antitumor and anticancer properties against breast cancer/carcinogenesis. Therefore, extracts and active principles of these spices could be explored in breast cancer chemoprevention and possibly therapeutically which may provide an avenue for reducing the risk and prevalence of breast cancer.

ChemInform Abstract: Biologically Active Metabolites of the Actinobacterium Streptomyces sp. GW 33/1593.

ChemInform ◽  
2009 ◽  
Vol 40 (30) ◽  
Author(s):  
M. P. Sobolevskaya ◽  
V. A. Denisenko ◽  
S. Fotso ◽  
H. Laach ◽  
N. I. Menzorova ◽  
...  
Keyword(s):  
Biologically Active ◽  
Active Metabolites ◽  
Streptomyces Sp ◽  
Biologically Active Metabolites
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