scholarly journals HUBUNGAN ANTARA TINGKAT KEPARAHAN PENYAKIT, AKTIVITAS FISIK DAN KUALITAS TIDUR TERHADAP KELELAHAN PADA PASIEN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)

2016 ◽  
Vol 5 (3) ◽  
pp. 221
Author(s):  
Rizky Ayu Fandika ◽  
Dyah Mahendrasari Sukendra
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Sampling Technique ◽  
Dominant Factor ◽  
Bivariate Analysis ◽  
P Value ◽  
Systemic Lupus ◽  
Cross Sectional ◽  
Factors Associated ◽  
R Value

ABSTRAK Systemic Lupus Erythematosus (SLE) merupakan penyakit autoimun yang prevalensinya tiap tahun meningkat di dunia maupun di Indonesia. Kelelahan yang parah dapat menyebabkan kekambuhan pada pasien SLE. Kelelahan merupakan gejala yang paling melemahkan dan mengganggu fungsi fisik, sosial dan emosional. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang berhubungan dengan kelelahan pada pasien SLE di Yayasan Lupus Indonesia Panggon Kupu Semarang. Jenis penelitian ini adalah penelitian deskriptif analitik dengan rancangan penelitian cross sectional. Sampel penelitian adalah 30 pasien SLE yang diperoleh dengan menggunakan teknik Total Sampling. Analisis data dilakukan secara univariat dan bivariat. Hasil analisis bivariat menunjukan faktor yang berhubungan dengan kelelahan yaitu: tingkat keparahan penyakit (r value = 0,853, sig = 0,00) dan kualitas tidur (r value = 0,796, sig = 0,00), dan faktor yang tidak berhubungan yaitu aktivitas fisik (r value = -0,79). Hasil analisis multivariat menunjukan faktor yang paling dominan yang berhubungan dengan kelelahan yaitu kualitas tidur (p value = 0,043, exp (OR) = 16,500) memiliki probabilitas terhadap terjadinya kelelahan sebesar 61,89%. Kata Kunci: Kelelahan, SLE. Systemic Lupus Erythematosus ( SLE ) was an autoimmune disease whose prevalence was increasing every year in the world as well as in Indonesia. Severe fatigue can lead to relapse in patients with SLE. Fatigue was a symptom of the most debilitating and interfere with the functioning of physical, social and emotional. The objective of the study to know factors associated with fatigue in patients SLE at Indonesian Lupus Panggon Kupu Foundation in Semarang City. This research was descriptive analytic research with Cross Sectional design. The samples were 30 patients with SLE were obtained using total sampling technique. Data analysis was performed using univariate and bivariate. Bivariate analysis results showed that factors associated with fatigue were: the severity of disease (r value = 0,853, sig = 0,00) and sleep quality (r value = 0,796, sig = 0,00), while the factors that was not associated were: physical activity (r value = -0,79). Multivariate analysis showed that the most dominant factor associated to the fatigue was the quality of sleep (p value = 0,043, exp (OR) = 16,500) have the probability of the occurrence of fatigue by 61.89 %.  

Hubungan Derajat Penyakit Terhadap Kualitas Tidur Pasien Systemic Lupus Erythematosus Di Komunitas Odapus Lampung

2021 ◽  
Vol 1 (4) ◽  
pp. 461-470
Author(s):  
Festy Ladyani Mustofa ◽  
Fitra Editama
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Sleep Quality ◽  
Lupus Erythematosus ◽  
Bivariate Analysis ◽  
P Value ◽  
Poor Sleep ◽  
Systemic Lupus ◽  
Chi Square ◽  
Cross Sectional ◽  
The Relationship

 ABSTRACT: RELATIONSHIP OF SLEEP DISEASE TO SLEEP QUALITY OF SYSTEMIC LUPUS ERYTHEMATOUS PATIENTS IN ODAPUS COMMUNITY LAMPUNGBackground: Systemic Lupus Erythematosus (SLE) is a disease that attacks the immune system that has no known cause and which can damage various organs of the human body. The clinical symptoms of SLE patients depend largely on the area of the organs involved. Symptoms of SLE are classified into three degrees, namely mild, moderate, and severe. Based on the evaluation of SLE disease activity, patients with SLE may experience sleep disturbances. So the authors conducted a study examining the relationship between degrees of disease and sleep quality. Objective: To determine the relationship between the degree of disease and the sleep quality ofpatients systemic lupus erythematosus in the ODAPUS community in Lampung 2020. Research Methods: this type of research is an observational analytic study with primary data using a questionnaire with aapproach cross-sectional. The sample of this study was all 40 patients who joined the ODAPUS community in Lampung. Data analysis used univariate and bivariate analysis using tables in data presentation. Results: From the results of the bivariate analysis, it is known that there is a significant relationship between the degree of disease and the sleep quality ofpatients systemic lupus erythematosus in the ODAPUS Lampung 2020 community. This is evidenced by thetest Chi Square with a P value of 0.008 with (α) = 5% then P <0.05. Also obtained an OR 11,625 (95% CI 1,467-92,139), which means that respondents with a severe disease degree were 11.625 times more likely to have poor sleep quality than those with mild disease degrees. Conclusion: There is a relationship between the degree of disease and the sleep quality ofpatients systemic lupus erythematosus in the ODAPUS community in Lampung 2020. Keywords: Disease Degree, Sleep Quality, SLE  INTISARI: HUBUNGAN DERAJAT PENYAKIT TERHADAP KUALITAS TIDUR PASIEN SYSTEMIC LUPUS ERYTHEMATOSUS DI KOMUNITAS ODAPUS LAMPUNG Latar Belakang: Systemic Lupus Erythematosus (SLE) merupakan penyakit yang menyerang sistem kekebalan tubuh yang tidak dapat diketahui  penyebabnya dan yang dapat merusak berbagai organ tubuh manusia. Gejala klinis dari pasien SLE sangat bergantung pada daerah organ yang terlibat. Gejala SLE dikelompokan menjadi tiga derajat yaitu ringan, sedang, dan berat. Berdasarkan evaluasi pada aktivitas penyakit SLE, pasien penderita SLE dapat mengalami gangguan tidur. Sehingga penulis melakukan penelitian yang mengkaji tentang hubungan derajat penyakit terhadap kualitas tidur.Tujuan: Untuk mengetahui hubungan antara derajat penyakit terhadap kualitas tidur pasien systemic lupus erythematosus di komunitas ODAPUS Lampung 2020.Metode Penelitian: Jenis penelitian ini adalah analitik observasional dengan data primer menggunakan kuesioner dengan pendekatan Cross- sectional. Sampel penelitian ini adalah seluruh pasien yang bergabung di komunitas ODAPUS Lampung sebanyak 40 orang. Analisis data menggunakan analisis univariat dan bivariat dengan menggunakan tabel dalam penyajian data.Hasil: Dari hasil analisis bivariat diketahui bahwa adanya hubungan yang bermakna antara derajat penyakit terhadap kualitas tidur pasien systemic lupus erythematosus di komunitas ODAPUS Lampung 2020. Hal ini dibuktikan berdasarkan uji Chi Square dengan nilai P value sebesar 0,008 dengan (α) = 5% maka P < 0,05. Diperoleh pula OR 11,625 (95% CI 1,467-92,139) yang berarti bahwa responden dengan derajat penyakit berat berpeluang 11,625 kali lebih besar memiliki kualitas tidur yang buruk dibandingkan dengan derajat penyakit yang ringan.Kesimpulan: Adanya hubungan antara derajat penyakit terhadap kualitas tidur pasien systemic lupus erythematosus di komunitas ODAPUS Lampung 2020. Kata Kunci : Derajat Penyakit, Kualitas Tidur, SLE

scholarly journals Prevalence of Hyposalivation in Patients with Systemic Lupus Erythematosus in a Brazilian Subpopulation

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Cristhiane Almeida Leite ◽  
Marcial Francis Galera ◽  
Mariano Martínez Espinosa ◽  
Paulo Ricardo Teles de Lima ◽  
Vander Fernandes ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Salivary Flow ◽  
Cross Sectional Study ◽  
Systemic Lupus ◽  
Cross Sectional ◽  
Mato Grosso ◽  
Significance Level ◽  
Factors Associated ◽  
Study Population

Background.Systemic lupus erythematosus (SLE) is a chronic inflammatory, multisystem, and autoimmune disease.Objective.The aim of this study was to describe the prevalence of hyposalivation in SLE patients and evaluate factors associated.Methods.This is a cross-sectional study developed at the Cuiaba University General Hospital (UNIC-HGU), Mato Grosso, Brazil. The study population consisted of female SLE patients treated at this hospital from 06/2010 to 12/2012. Unstimulated salivary flow rates (SFRs) were measured. Descriptive and inferential analyses were performed in all cases using a significance levelP<0.05.Results.The results showed that 79% of patients with systemic lupus erythematosus suffered from hyposalivation and that the disease activity and age in years were the factors that resulted in statistically significant differences.Conclusion.The activity of the disease, age >27 years, and the drugs used were factors associated with hyposalivation, resulting in a statistically significant decrease in saliva production.

scholarly journals Hubungan Derajat Aktivitas Penyakit Lupus Eritematosus Sistemik Berdasarkan Skor Mex-Sledai Dengan Kejadian Anemia Pada Penderita Lupus Eritematosus Sistemik Di Komunitas Odapus Lampung

2021 ◽  
Vol 3 (2) ◽  
pp. 192-202
Author(s):  
Rina Kirwiastiny ◽  
Ringgo Alfarisi ◽  
Hidayat Hidayat ◽  
Ageel Al-Aziz Marjaen
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Chronic Disease ◽  
Lupus Erythematosus ◽  
Deficiency Anemia ◽  
P Value ◽  
Systemic Lupus Erythematous ◽  
Systemic Lupus ◽  
Immune Disease ◽  
Cross Sectional ◽  
Sledai Score

ABSTRACT : RELATIONSHIP OF SYSTEMIC LUPUS ERYTHEMATOSUS ACTIVITIES BASED ON MEX-SLEDAI SCORE WITH INCIDENCE OF ANEMIA IN SYSTEMIC LUPUS ERYTHEMATOUS PATIENTS IN THE ODAPUS LAMPUNG COMMUNITY, 2020Background : Systemic Lupus Erytematosus (SLE) is a complex autoimmune disease characterized by the presence of autoantibodies against the cell nucleus and involving many organ systems in the body. Anemia in LES patients varies between chronic disease anemia, hemolytic anemia, blood loss, renal insufficiency, infection, myelodysplasia, and aplastic anemia. What often occurs in LES anemia is due to erythropoesis suppression due to chronic inflammation. Anemia in LES patients is an immune or non-immune disease. Anemia is a non-immune disease is anemia in chronic disease, iron deficiency anemia, sideroblastic anemia, anemia in kidney disease, anemia indicated by drugs, and anemia secondary to other diseases (eg sickle cell anemia).Research purposes : This study was to determine the degree of activity of systemic lupus erythematosus based on max-sledai and hemoglobin levels in systemic lupus erythematous patients in the ODAPUS Lampung community in 2020.Methode :The analytical observational method was used using a cross sectional approach. The research subjects were 30 respondents who used the total sampling technique from members of the ODAPUS Lampung community by conducting MEX-SLEDAI interviews and blood sampling conducted from November 2019 to February 2020. Statistical test used Fisher exact test.Results: From 30 study subjects, disease activity based on MEX-SLEDAI was above the average of 21 patients (70%). And the results of blood tests were 18 patients (60%) who were not anemia and 12 patients (40%) had anemia.Conclusion     : There was a significant relationship between the degree of activity of Systemic Lupus Erythematosus based on the MEX-SLEDAI score and the incidence of anemia with p value = 0.024 meaning the p value ≤ 0.05. Keywords      : LES; Incidence of Anemia; MEX-SLEDAI    INTISARI : HUBUNGAN DERAJAT AKTIVITAS PENYAKIT LUPUS ERITEMATOSUS SISTEMIK BERDASARKAN SKOR  MEXSLEDAI DENGAN KEJADIAN ANEMIA PADA PENDERITA LUPUS ERITEMATOUS SISTEMIK DI KOMUNITAS ODAPUS LAMPUNG  Latar belakang : Systemic Lupus Erytematosus (SLE) merupakan penyakit autoimun yang kompleks ditandai oleh adanya autoantibodi terhadap inti sel dan melibatkan banyak sistem organ dalam tubuh. Anemia pada pasien LES bervariasi antara anemia penyakit kronis, anemia hemolitik, kehilangan darah, insufisiensi ginjal, infeksi, mielodisplasia, dan anemia aplastik. Yang sering terjadi anemia pada LES disebabkan supresi eritropoesis karena inflamasi yang kronis.  Anemia pada pasien LES merupakan penyakit imun atau non-imun. Anemia merupakan penyakit non-imun adalah anemia pada penyakit kronik ,anemia defisiensi besi, anemia sideroblastik, anemia pada penyakit ginjal, anemia indikasi obat, dan anemia sekunder terhadap penyakit lain ( misalnya anemia sel sabit ).Tujuan Penelitian : Penelitian ini untuk mengetahui hubungan drajat aktivitas penyakit lupus eritematosus sistemik berdasarkan max-sledai dengan kadar hemoglobin pada penderita lupus eritematous sistemik di komunitas ODAPUS lampung tahun 2020.Metode : Digunakan metode observasional analitik menggunakan pendekatan cross sectional. Subjek penelitian sebanyak 30 responden yang menggunakan teknik total sampling dari anggota komunitas ODAPUS Lampung dengan melakukan wawancara MEX-SLEDAI dan pengambilan sampel darah yang dilakukan pada bulan November 2019 s/d Februari 2020. Uji statistic menggunakan Fisher exact test.Hasil : Dari 30 subjek penelitian didapatkan aktifitas penyakit berdasarkan MEX-SLEDAI di atas rata – rata sebanyak 21 pasien (70%). Dan hasil peneriksaan darah yaitu 18 pasien (60%) yang Tidak anemia dan yang mengalami Anemia ada 12 pasien (40%).Kesimpulan   : Terdapat hubungan bermakna antara derajat aktivitas penyakit Lupus Eritematosus Sistemik berdasarkan skor MEX-SLEDAI dengan Kejadian Anemia dengan p value =0.024 berarti nilai p value ≤ 0.05. Kata Kunci     : LES; Kejadian Anemia; MEX-SLEDAI

Hubungan Aktifitas Penyakit SLE (Systemic Lupus Erythematosus) Berdasarkan Mex-Sledai Scoring Terhadap Depresi Di Komunitas Odapus Kota Bandar Lampung

2021 ◽  
Vol 1 (4) ◽  
pp. 370-382
Author(s):  
Rina Kriswiastiny ◽  
Festy Ladyani Mustofa ◽  
Syuhada Syuhada ◽  
Reychan Gustiawan Putra
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Disease Activity ◽  
Lupus Erythematosus ◽  
Health Sector ◽  
Point Of View ◽  
P Value ◽  
Systemic Lupus Erythematosus Disease ◽  
Systemic Lupus ◽  
Cross Sectional ◽  
Cross Sectional Design

ABSTRACT: RELATIONSHIP OF SLE (SYSTEMIC LUPUS ERYTHEMATOSUS) ACTIVITIES BASED ON MEX-SLEDAI SCORING ON DEPRESSION IN ODAPUS COMMUNITIES BANDAR LAMPUNG Background: Depression is a clinical manifestation that can occur in patients with SLE and it is suspected that the level of SLE disease activity can affect these events (Nery, et al. 2007). Ironically, this section is a part that is often overlooked by many people, including the health sector. In fact, by understanding this point of view, cross-scientific collaborative treatment such as the Internal and Psychiatry Fields can be done to improve the treatment and quality of life of patients.Objective: To determine the relationship between SLE (Systemic lupus Erythematosus) disease activity based on MEX-SLEDAI Scoring against depression in the Odapus Community, Bandar Lampung City 2020.Methodology: The type of research used in this study is correlative analytic with cross-sectional design. The sample used in this study were patients with SLE (Systemic lupus Erythematosus) based on MEX-SLEDAI Scoring for depression in the Odapus Community, Bandar Lampung City 2020. Data analysis used the Spearman test.Results: In the activity variable SLE and depression, the P value = 0.001 (P <0.05) with a correlation value of r = 0.490 was obtained.Conclusion: There is a relationship between SLE (Systemic lupus Erythematosus) disease activity based on MEX-SLEDAI Scoring against depression in Odapus Community, Bandar Lampung City 2020 with moderate correlation strength. Keywords: Lupus, Depression, MEX-Sledai  INTISARI: HUBUNGAN AKTIFITAS PENYAKIT SLE (SYSTEMIC LUPUS ERYTHEMATOSUS)  BERDASARKAN MEX-SLEDAI SCORING TERHADAP DEPRESI DI KOMUNITAS ODAPUS KOTA BANDAR LAMPUNGLatar Belakang: Depresi merupakan manifestasi klinis yang dapat muncul pada penderita SLE dan diduga tingkat aktivitas penyakit SLE dapat mempengaruhi kejadian-kejadian tersebut (Nery, dkk. 2007). Ironisnya, bagian ini merupakan bagian yang sering luput diperhatikan oleh banyak orang, termasuk bidang kesehatan. Padahal, dengan memahami sudut pandang ini, pengobatan kolaboratif lintas keilmuan seperti Bidang Interna dengan Bidang Psikiatri dapat dilakukan untuk meningkatkan pengobatan dan kualitas hidup pasien.Tujuan: Untuk mengetahui hubungan aktifitas penyakit SLE (Systemic lupus Erythematosus) berdasarkan MEX-SLEDAI Scoring terhadap depresi di Komunitas Odapus Kota Bandar Lampung 2020.Metodologi: Jenis penelitian yang digunakan dalam penelitian ini adalah analitik korelatif dengan desain cross sectional. Sampel yang digunakan pada penelitian ini adalah penderita penyakit SLE (Systemic lupus Erythematosus) berdasarkan MEX-SLEDAI Scoring terhadap depresi di Komunitas Odapus Kota Bandar Lampung 2020. Analisa data menggunakan Uji Spearman.Hasil: Pada variabel aktifitas penyakit SLE dan depresi diperoleh nilai P value = 0,001 (P<0,05) dengan nilai korelasi r = 0,490.Kesimpulan: Terdapat hubungan aktifitas penyakit SLE (Systemic lupus Erythematosus) berdasarkan MEX-SLEDAI Scoring terhadap depresi di Komunitas Odapus Kota Bandar Lampung 2020 dengan kekuatan korelasi sedang.Kata Kunci     : Lupus, Depresi, MEX-Sledai

scholarly journals Fasting triglycerides and glucose index: a useful screening test for assessing insulin resistance in patients diagnosed with rheumatoid arthritis and systemic lupus erythematosus

2019 ◽  
Vol 11 (1) ◽  
Author(s):  
Betsabe Contreras-Haro ◽  
Sandra Ofelia Hernandez-Gonzalez ◽  
Laura Gonzalez-Lopez ◽  
Maria Claudia Espinel-Bermudez ◽  
Leonel Garcia-Benavides ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Systemic Lupus Erythematosus ◽  
Insulin Resistance ◽  
Lupus Erythematosus ◽  
Screening Test ◽  
Systemic Lupus ◽  
Cross Sectional ◽  
Factors Associated ◽  
Tyg Index ◽  
Surrogate Index

Abstract Background Insulin resistance (IR) is frequently observed in patients with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE). In clinical practice, IR assessment is limited to a low proportion of patients due to cost and equipment and technical expertise requirements. The surrogate index of triglycerides and glucose (TyG index) has been validated in non-rheumatic populations, showing adequate sensitivity and specificity for IR, although this index has not yet been used in connective tissue disorders. The aim of this study was to evaluate the frequency of insulin resistance (IR) using the validated surrogate index of triglycerides and glucose (TyG index) and to explore factors associated with IR in Mexican women with RA or SLE. Methods Ninety-five female RA and 57 SLE patients were included in a cross-sectional study. Clinical and epidemiological variables were evaluated. IR was assessed using the TyG index with a cutoff value of > 4.68. Logistic regression analysis was performed to identify factors associated with IR excluding confounders. Results IR frequency in the entire sample was 50%, higher than the 10% observed in non-rheumatic controls (p < 0.001). The frequency of IR was similar in SLE (49.1%) and RA (50.5%, p = 0.8) patients. IR was associated with a longer duration of hypertension and higher total cholesterol and low density lipoprotein cholesterol levels. Based on multivariate analysis, the duration of hypertension (OR: 1.06; 95% CI 1.002–1.12, p = 0.04), waist circumference (OR: 1.04; 95% CI 1.01–1.08, p = 0.007), uric acid levels (OR: 1.46; 95% CI 1.08–1.97, p = 0.01), RA (OR: 4.87; 95% CI 1.31–18.78, p = 0.01) and SLE (OR: 4.22; 95% CI 1.06–16.74, p = 0.04) were the main risk factors for IR. Conclusions This study shows that the TyG index is a useful screening test for IR in RA and SLE patients. Future longitudinal studies should be performed with the aim of identifying the predictive value of TyG index results for identifying complications linked to IR.

scholarly journals Factors associated with pericardial effusion in pediatric systemic lupus erythematosus

2018 ◽  
Vol 58 (5) ◽  
pp. 227-32
Author(s):  
Pediana Rachmawati ◽  
Indah K. Murni ◽  
Sasmito Nugroho ◽  
Noormanto Noormanto ◽  
Sumadiono Sumadiono
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Pericardial Effusion ◽  
Hemolytic Anemia ◽  
Lupus Erythematosus ◽  
Medical Records ◽  
Multivariate Logistic Regression Analysis ◽  
Systemic Lupus ◽  
Cross Sectional ◽  
Pediatric Systemic Lupus Erythematosus ◽  
Factors Associated

Background Cardiovascular involvement in systemic lupus erythematosus (SLE) has been reported to range from 4-78%. Complications can affect all structures of the heart, including the endocardium, myocardium, pericardium, and valves. Pericarditis is the most common manifestation, with an incidence of 11-54% in SLE patients. Pericardial effusion is often observed in patients with pericarditis, and can be confirmed by echocardiography. Objective To determine factors associated with pericardial effusion in children with SLE. Methods We conducted a restrospective cross-sectional study by reviewing medical records of children with SLE aged less than 18 years who underwent echocardiography at the Dr. Sardjito Hospital. Yogyakarta, from January 2011 to March 2018. Patients with congenital heart disease or incomplete medical records were excluded. A multivariate logistic regression analysis was done to determine factors that independetly associated with pericardial effusion. Results Among 165 children with SLE, 73 fulfilled the inclusion criteria. The prevalence of pericardial effusion was 54.8%. Median age was 13 (range 5-17) years and the female-to-male ratio was 8:1. Hemolytic anemia (OR=4.135; 95%CI 1.039 to 16.453; P=0.044) was significantly associated with pericardial effusion. Conclusion Hemolytic anemia is significantly associated with pericardial effusion in children with SLE.

scholarly journals Hubungan Derajat Aktivitas Penyakit Lupus Eritematosus Sistemik Berdasarkan Skor Mex-Sledai Dengan Kejadian Anemia Pada Penderita Lupus Eritematosus Sistemik Di Komunitas Odapus Lampung

2021 ◽  
Vol 3 (2) ◽  
pp. 192-202
Author(s):  
Rina Kirwiastiny ◽  
Ringgo Alfarisi ◽  
Hidayat Hidayat ◽  
Ageel Al-Aziz Marjaen
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Chronic Disease ◽  
Lupus Erythematosus ◽  
Deficiency Anemia ◽  
P Value ◽  
Systemic Lupus Erythematous ◽  
Systemic Lupus ◽  
Immune Disease ◽  
Cross Sectional ◽  
Sledai Score

ABSTRACT : RELATIONSHIP OF SYSTEMIC LUPUS ERYTHEMATOSUS ACTIVITIES BASED ON MEX-SLEDAI SCORE WITH INCIDENCE OF ANEMIA IN SYSTEMIC LUPUS ERYTHEMATOUS PATIENTS IN THE ODAPUS LAMPUNG COMMUNITY, 2020Background : Systemic Lupus Erytematosus (SLE) is a complex autoimmune disease characterized by the presence of autoantibodies against the cell nucleus and involving many organ systems in the body. Anemia in LES patients varies between chronic disease anemia, hemolytic anemia, blood loss, renal insufficiency, infection, myelodysplasia, and aplastic anemia. What often occurs in LES anemia is due to erythropoesis suppression due to chronic inflammation. Anemia in LES patients is an immune or non-immune disease. Anemia is a non-immune disease is anemia in chronic disease, iron deficiency anemia, sideroblastic anemia, anemia in kidney disease, anemia indicated by drugs, and anemia secondary to other diseases (eg sickle cell anemia).Research purposes : This study was to determine the degree of activity of systemic lupus erythematosus based on max-sledai and hemoglobin levels in systemic lupus erythematous patients in the ODAPUS Lampung community in 2020.Methode :The analytical observational method was used using a cross sectional approach. The research subjects were 30 respondents who used the total sampling technique from members of the ODAPUS Lampung community by conducting MEX-SLEDAI interviews and blood sampling conducted from November 2019 to February 2020. Statistical test used Fisher exact test.Results: From 30 study subjects, disease activity based on MEX-SLEDAI was above the average of 21 patients (70%). And the results of blood tests were 18 patients (60%) who were not anemia and 12 patients (40%) had anemia.Conclusion     : There was a significant relationship between the degree of activity of Systemic Lupus Erythematosus based on the MEX-SLEDAI score and the incidence of anemia with p value = 0.024 meaning the p value ≤ 0.05. Keywords      : LES; Incidence of Anemia; MEX-SLEDAI    INTISARI : HUBUNGAN DERAJAT AKTIVITAS PENYAKIT LUPUS ERITEMATOSUS SISTEMIK BERDASARKAN SKOR  MEXSLEDAI DENGAN KEJADIAN ANEMIA PADA PENDERITA LUPUS ERITEMATOUS SISTEMIK DI KOMUNITAS ODAPUS LAMPUNG  Latar belakang : Systemic Lupus Erytematosus (SLE) merupakan penyakit autoimun yang kompleks ditandai oleh adanya autoantibodi terhadap inti sel dan melibatkan banyak sistem organ dalam tubuh. Anemia pada pasien LES bervariasi antara anemia penyakit kronis, anemia hemolitik, kehilangan darah, insufisiensi ginjal, infeksi, mielodisplasia, dan anemia aplastik. Yang sering terjadi anemia pada LES disebabkan supresi eritropoesis karena inflamasi yang kronis.  Anemia pada pasien LES merupakan penyakit imun atau non-imun. Anemia merupakan penyakit non-imun adalah anemia pada penyakit kronik ,anemia defisiensi besi, anemia sideroblastik, anemia pada penyakit ginjal, anemia indikasi obat, dan anemia sekunder terhadap penyakit lain ( misalnya anemia sel sabit ).Tujuan Penelitian : Penelitian ini untuk mengetahui hubungan drajat aktivitas penyakit lupus eritematosus sistemik berdasarkan max-sledai dengan kadar hemoglobin pada penderita lupus eritematous sistemik di komunitas ODAPUS lampung tahun 2020.Metode : Digunakan metode observasional analitik menggunakan pendekatan cross sectional. Subjek penelitian sebanyak 30 responden yang menggunakan teknik total sampling dari anggota komunitas ODAPUS Lampung dengan melakukan wawancara MEX-SLEDAI dan pengambilan sampel darah yang dilakukan pada bulan November 2019 s/d Februari 2020. Uji statistic menggunakan Fisher exact test.Hasil : Dari 30 subjek penelitian didapatkan aktifitas penyakit berdasarkan MEX-SLEDAI di atas rata – rata sebanyak 21 pasien (70%). Dan hasil peneriksaan darah yaitu 18 pasien (60%) yang Tidak anemia dan yang mengalami Anemia ada 12 pasien (40%).Kesimpulan   : Terdapat hubungan bermakna antara derajat aktivitas penyakit Lupus Eritematosus Sistemik berdasarkan skor MEX-SLEDAI dengan Kejadian Anemia dengan p value =0.024 berarti nilai p value ≤ 0.05. Kata Kunci     : LES; Kejadian Anemia; MEX-SLEDAI

scholarly journals Factors associated with the use of complementary therapies in Taiwanese patients with systemic lupus erythematosus: a cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ming-Chi Lu ◽  
Hui-Chin Lo ◽  
Hsiu-Hua Chang ◽  
Chia-Wen Hsu ◽  
Malcolm Koo
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Complementary Therapies ◽  
Complementary Therapy ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Systemic Lupus ◽  
Cross Sectional ◽  
Factors Associated

Abstract Background This study aimed to investigate the prevalence of and the factors associated with the regular use of complementary therapies for Taiwanese patients with systemic lupus erythematosus (SLE). Methods In this cross-sectional study, 351 patients with SLE were consecutively recruited from a regional hospital in southern Taiwan from April to August 2019. Demographic and clinical information, including the use of different types of complementary therapies, was ascertained using a self-constructed questionnaire. Disease-specific quality of life was measured using the Lupus Quality of Life (LupusQoL) questionnaire. SLE disease activity was assessed using the rheumatologist-scored Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2 K). Factors associated with the regular use of complementary therapies were evaluated using multiple logistic regression analyses. Results Of the 351 patients with SLE, 90.3% were female, and 60.1% were ≥ 40 years of age. The prevalence of the regular use of any type of complementary therapy was 85.5%. The five most popular types of complementary therapy used were (1) fitness walking or strolling, (2) Buddhist prayer or attending temple, (3) vitamin consumption, (4) calcium supplementation, and (5) fish oil supplementation. Multiple logistic regression analyses revealed that the significant and independent factors associated with the regular use of complementary therapies in patients with SLE were age ≥ 40 years (adjusted odds ratio [aOR] 2.76, p = 0.013), nonoverweight or nonobesity (aOR 0.29, p = 0.004), engagement in vigorous exercise in the past year (aOR 4.62, p = 0.002), a lower SLEDAI-2 K score (aOR 0.90, p = 0.029), and a lower score in the physical health domain of the LupusQoL (aOR 0.57, p = 0.001). Conclusions A high prevalence of complementary therapy use in Taiwanese patients with SLE was observed. Rheumatologists should routinely ask patients about their use of supplements to minimize the risk of interaction with medical therapy.

scholarly journals Utilization of Puskesmas in Efforts to Prevent COVID-19 in Bengkulu City

2021 ◽  
Vol 16 (1) ◽  
pp. 16-24
Author(s):  
Oktarianita Oktarianita ◽  
Andry Sartika ◽  
Nopia Wati ◽  
Bintang Agustina Pratiwi
Keyword(s):  
Quantitative Research ◽  
Sampling Technique ◽  
Cross Sectional Study ◽  
Vital Role ◽  
Dominant Factor ◽  
Bivariate Analysis ◽  
P Value ◽  
Design Data ◽  
Cross Sectional ◽  
Research Population

Background: Puskesmas as First Level Health Facilities (FKTP) plays a vital role during the Covid-19 pandemic in preventing and controlling the number of Covid-19 cases by anticipating, detecting, responding to events. However, at this time, the puskesmas are still underutilized by the community. The highest confirmed positive cases in Bengkulu City were in the Gading Cempaka District, with 990 cases. This study aimed to determine the variables related to the utilization of puskesmas in Bengkulu City. Methods: This research was quantitative research with a cross-sectional study design. Data collection was carried out by distributing questionnaires to respondents using an accidental sampling technique executed in March-August 2021. The research population was the entire community of Bengkulu City, with a sample of 110 respondents from the Gading Cempaka District, Bengkulu City. Data were analyzed by univariate to multivariate logistic regression. Results: The results show that 88 respondents (78.2%) have utilized the puskesmas, as many as 86 (78.2%) were female, 86 respondents (60.9%) belonged to the young age group, respondents with higher education were 73 respondents ( 66.4%), 73 respondents (66.4%) worked and as many as 79 respondents (71.8%) have income <UMP. The bivariate analysis results showed that the factors related to the utilization of the puskesmas (p<0.05) were variables of age, education, occupation, and income despite no relationship between gender, distance, knowledge, and family support (p>α). The results of the multivariate analysis showed that education was the dominant factor influencing the utilization of the puskesmas with (p-value = 0.010; B = 2.707; 95% CI = 1.892-118.569). Conclusion: The community has taken advantage of the puskesmas in terms of preventing Covid-19. The utilization of puskesmas is affected by age and education level.

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