Hubungan Derajat Penyakit Terhadap Kualitas Tidur Pasien Systemic Lupus Erythematosus Di Komunitas Odapus Lampung

2021 ◽  
Vol 1 (4) ◽  
pp. 461-470
Author(s):  
Festy Ladyani Mustofa ◽  
Fitra Editama
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Sleep Quality ◽  
Lupus Erythematosus ◽  
Bivariate Analysis ◽  
P Value ◽  
Poor Sleep ◽  
Systemic Lupus ◽  
Chi Square ◽  
Cross Sectional ◽  
The Relationship

 ABSTRACT: RELATIONSHIP OF SLEEP DISEASE TO SLEEP QUALITY OF SYSTEMIC LUPUS ERYTHEMATOUS PATIENTS IN ODAPUS COMMUNITY LAMPUNGBackground: Systemic Lupus Erythematosus (SLE) is a disease that attacks the immune system that has no known cause and which can damage various organs of the human body. The clinical symptoms of SLE patients depend largely on the area of the organs involved. Symptoms of SLE are classified into three degrees, namely mild, moderate, and severe. Based on the evaluation of SLE disease activity, patients with SLE may experience sleep disturbances. So the authors conducted a study examining the relationship between degrees of disease and sleep quality. Objective: To determine the relationship between the degree of disease and the sleep quality ofpatients systemic lupus erythematosus in the ODAPUS community in Lampung 2020. Research Methods: this type of research is an observational analytic study with primary data using a questionnaire with aapproach cross-sectional. The sample of this study was all 40 patients who joined the ODAPUS community in Lampung. Data analysis used univariate and bivariate analysis using tables in data presentation. Results: From the results of the bivariate analysis, it is known that there is a significant relationship between the degree of disease and the sleep quality ofpatients systemic lupus erythematosus in the ODAPUS Lampung 2020 community. This is evidenced by thetest Chi Square with a P value of 0.008 with (α) = 5% then P <0.05. Also obtained an OR 11,625 (95% CI 1,467-92,139), which means that respondents with a severe disease degree were 11.625 times more likely to have poor sleep quality than those with mild disease degrees. Conclusion: There is a relationship between the degree of disease and the sleep quality ofpatients systemic lupus erythematosus in the ODAPUS community in Lampung 2020. Keywords: Disease Degree, Sleep Quality, SLE  INTISARI: HUBUNGAN DERAJAT PENYAKIT TERHADAP KUALITAS TIDUR PASIEN SYSTEMIC LUPUS ERYTHEMATOSUS DI KOMUNITAS ODAPUS LAMPUNG Latar Belakang: Systemic Lupus Erythematosus (SLE) merupakan penyakit yang menyerang sistem kekebalan tubuh yang tidak dapat diketahui  penyebabnya dan yang dapat merusak berbagai organ tubuh manusia. Gejala klinis dari pasien SLE sangat bergantung pada daerah organ yang terlibat. Gejala SLE dikelompokan menjadi tiga derajat yaitu ringan, sedang, dan berat. Berdasarkan evaluasi pada aktivitas penyakit SLE, pasien penderita SLE dapat mengalami gangguan tidur. Sehingga penulis melakukan penelitian yang mengkaji tentang hubungan derajat penyakit terhadap kualitas tidur.Tujuan: Untuk mengetahui hubungan antara derajat penyakit terhadap kualitas tidur pasien systemic lupus erythematosus di komunitas ODAPUS Lampung 2020.Metode Penelitian: Jenis penelitian ini adalah analitik observasional dengan data primer menggunakan kuesioner dengan pendekatan Cross- sectional. Sampel penelitian ini adalah seluruh pasien yang bergabung di komunitas ODAPUS Lampung sebanyak 40 orang. Analisis data menggunakan analisis univariat dan bivariat dengan menggunakan tabel dalam penyajian data.Hasil: Dari hasil analisis bivariat diketahui bahwa adanya hubungan yang bermakna antara derajat penyakit terhadap kualitas tidur pasien systemic lupus erythematosus di komunitas ODAPUS Lampung 2020. Hal ini dibuktikan berdasarkan uji Chi Square dengan nilai P value sebesar 0,008 dengan (α) = 5% maka P < 0,05. Diperoleh pula OR 11,625 (95% CI 1,467-92,139) yang berarti bahwa responden dengan derajat penyakit berat berpeluang 11,625 kali lebih besar memiliki kualitas tidur yang buruk dibandingkan dengan derajat penyakit yang ringan.Kesimpulan: Adanya hubungan antara derajat penyakit terhadap kualitas tidur pasien systemic lupus erythematosus di komunitas ODAPUS Lampung 2020. Kata Kunci : Derajat Penyakit, Kualitas Tidur, SLE

scholarly journals Hubungan antara Nyeri Fraktur dengan Kualitas Tidur Pasien yang di Rawat Inap

2019 ◽  
Vol 1 (1) ◽  
pp. 55-64
Author(s):  
Juli Andri ◽  
Panzilion Panzilion ◽  
Tri Sutrisno
Keyword(s):  
Sleep Quality ◽  
Univariate Analysis ◽  
Bivariate Analysis ◽  
P Value ◽  
Poor Sleep ◽  
Cross Sectional ◽  
Keywords Fracture ◽  
The Relationship ◽  
Severe Fracture

  This study aims to determine the relationship between fracture pain and sleep quality. This research was conducted in the Seruni room of Dr. M. Yunus Bengkulu and in the Seruni room at Bhayangkara Hospital TK III Bengkulu. The research design used was correlational using a cross sectional approach. The results of the univariate analysis showed that (73.3%) respondents had poor sleep quality and (60%) had severe fracture pain intensity. The results of bivariate analysis with correlation test obtained p-value = 0.002 (p <0.05). In conclusion, there is a relationship between fracture pain and the sleep quality of patients hospitalized at the hospital in Bengkulu Province.   Keywords: Fracture Pain, Sleep Quality

scholarly journals HUBUNGAN SENAM LANSIA DENGAN KUALITAS TIDUR LANSIA

2018 ◽  
Vol 2 (1) ◽  
pp. 1
Author(s):  
Farid Fatkhurroji ◽  
Siti Munawaroh ◽  
Cholik Harun Rosjidi
Keyword(s):  
Sleep Quality ◽  
The Elderly ◽  
P Value ◽  
Poor Sleep ◽  
Chi Square ◽  
Cross Sectional ◽  
A Value ◽  
Knowledge And Attitude ◽  
Relationship Of ◽  
The Relationship

AbstactElderly gymnastics is a sport and helps the elderly body to stay fit and stay fresh. Elderly body fitness will affect sleep patterns, because sleep is a very important requirement for human health, but not all humans can obtain the need for sleep berkuailitas in because of a problem, especially in the elderly. This study aims to determine the relationship of Elderly Gymnastics on Sleep Quality Elderly. The design of this research is Correlation with cross sectional approach. Sample size was 47 respondents. Sampling of research using Purprosive Sampling, collecting data using questioner and calculation using Chi-square Correlation test by using SPSS 17.0 error α 0,05. The results of variables of elderly gymnastics interpreted that 28 respondents (56.9%) actively followed and almost half of 19 respondents (40.4%) did not actively follow. In the elderly sleep quality variables interpreted most of the 25 respondents (53.2%) sleep quality is good, and almost half of 22 respondents (46.8%) poor sleep quality. Based on the calculation of Chi-square statistical test obtained p value = 0,000 which means smaller than α = 0.05 with a value of cc = 0,525 sufficient category. Then there is the relationship between Elderly Gymnastics with Quality Elderly Sleep at Posyandu Lestari Lansia Mojorejo Village, District Park, Madiun District in 2017 with close enough relationship. The results of this study concluded almost half of the inactivity following gymnastics because of knowledge and attitude about gymnastics, the researchers suggested the next researcher to examine the relationship of elderly perceptions about the activities of gymnastics with Sleep Quality Elderly.Keywords: Gymnastics, Elderly, Sleep Quality.AbstrakSenam lansia merupakan olahraga dan membantu tubuh lansia agar tetap bugar dan tetap segar. Kebugaran tubuh lansia akan mempengaruhi pola tidur, karena tidur merupakan suatu kebutuhan yang sangat penting untuk kesehatan manusia, tetapi tidak semua manusia dapat memperoleh kebutuhan tidur yang berkuailitas di karenakan suatu masalah khususnya pada lansia. Penelitian ini bertujuan untuk mengetahui Hubungan Senam Lansia Dengan Kualitas Tidur Lansia. Desain penelitian ini adalah Korelasi dengan pendekatan cross sectional. Besar sampel 47 responden. Sampling penelitian menggunakan Purprosive Sampling, pengumpulan data menggunakan kuesioner dan perhitungan menggunakan uji Korelasi Chi-square dengan menggunakan SPSS 17.0 kesalahan α 0,05. Hasil penelitian variabel senam lansia diinterpretasikan bahwa 28 responden (56,9%) aktif mengikuti dan hampir setengahnya 19 responden (40,4%) tidak aktif mengikuti. Pada variabel kualitas Tidur Lansia diinterpretasikan sebagian besar 25 responden (53,2%) kualitas tidur baik, dan hampir setengahnya 22 responden (46,8%) kualitas tidur buruk. Berdasarkan perhitungan uji statistik Chi-square diperoleh p value = 0,000 yang berarti lebih kecil dari α= 0,05 dengan nilai cc=0,525 kategori cukup. Maka ada hubungan antara Senam Lansia Dengan Kualitas Tidur Lansia di Posyandu Lestari Lansia Kelurahan Mojorejo, Kecamatan Taman, Kabupaten Madiun tahun 2017 dengan keeratan hubungan cukup. Hasil penelitian disimpulkan hampir setengahnya tidak aktif mengikuti senam karena faktor pengetahuan dan sikap tentang senam, maka peneliti menyarankan pada peneliti selanjutnya untuk meneliti tentang hubungan persepsi lansia tentang kegiatan senam dengan Kualitas Tidur Lansia.Kata kunci: Senam, Lansia, Kualitas Tidur.

scholarly journals Resilience and Treatment Adhesion in Patients with Systemic Lupus Erythematosus

2014 ◽  
Vol 8 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Daniella Antunes Pousa Faria ◽  
Luciana Silva Revoredo ◽  
Maria José Vilar ◽  
Maia Eulália Maria Chaves
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Demographic Data ◽  
Working Hours ◽  
Cross Sectional Study ◽  
P Value ◽  
Systemic Lupus ◽  
Chi Square ◽  
Access To Treatment ◽  
Cross Sectional

Background: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune, rheumatic inflammatory disease that can cause significant morbidity with evident psychological impacts and obvious harm to quality-of-life that require the patient to adapt treatment. Objective: Assessment of resilience and the self-reported treatment adhesion behaviors of patients with SLE, investigating which of these factors are associated to resilience. Method: Cross-sectional study of 40 women with SLE. A questionnaire with social demographic data, health history and the Wagnild Young Resilience Scale were used. Results: 62.5% followed the medical treatment properly but 55% found it difficult. 27.5% of the patients presented low resilience, 57.5% medium and 15% high resilience. Resilience was associated in the chi-square test (p-value < 0.05) with the variables work, understanding SLE, trying to find out about SLE, following the treatment correctly, difficulty in following the treatment and stopping some activity because of the disease. In the correlation analysis, resilience was associated with age (-0.3960), number of working hours (0.5533), specialized treatment duration (-0.8103) and disease duration from diagnosis (-0.8014). Conclusion: Patients with high resilience tended to follow treatment correctly, tried to understand the disease and adhered more to the treatment to avoid risks and promote protection factors. Therefore knowledge of resilience in patients with SLE is necessary. It is important that the state takes necessary actions to facilitate access to treatment, to educational programs and to medical support. Awareness and counselling sessions must be initiated to develop and promote individual capacities to learn how to tackle with the disease for which psychological support of family and doctors can play a significant role.

scholarly journals The Relationship Between Gadget Usage and Adolescent Sleep Quality

2021 ◽  
Vol 4 (1) ◽  
pp. 23-27
Author(s):  
Indi Ivana ◽  
Murniati Murniati ◽  
Noor Rochmah Ida Ayu Trisno Putri
Keyword(s):  
Sleep Quality ◽  
P Value ◽  
Poor Sleep ◽  
Quality Of Sleep ◽  
Chi Square ◽  
Cross Sectional ◽  
Adolescent Sleep ◽  
Chi Square Test ◽  
The Relationship

Introduction: Adolescent are very interested in gadgets that make it easier for them to carry out various social activities. One of the problems that can arise from gadget overuse is decreased quality of sleep. The purpose of this study was to determine the relationship between gadget usage behavior and adolescent sleep quality. Methods: Cross-sectional design was used in this study. Ninety-nine respondents had chosen with a proportionate stratified random sampling. Analysis was done by Chi square test. Results: Data analysis showed that 84.8% of the respondents were categorized as gadget addiction and 80.8% of the respondents experienced poor sleep quality. The relationship between gadget usage and sleep quality was significant with a p-value of 0.0001. Conclusion: There was a relationship between gadget usage and sleep quality in adolescents, in which gadget dependency had poorer quality of sleep.

scholarly journals HUBUNGAN ANTARA TINGKAT KEPARAHAN PENYAKIT, AKTIVITAS FISIK DAN KUALITAS TIDUR TERHADAP KELELAHAN PADA PASIEN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)

2016 ◽  
Vol 5 (3) ◽  
pp. 221
Author(s):  
Rizky Ayu Fandika ◽  
Dyah Mahendrasari Sukendra
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Sampling Technique ◽  
Dominant Factor ◽  
Bivariate Analysis ◽  
P Value ◽  
Systemic Lupus ◽  
Cross Sectional ◽  
Factors Associated ◽  
R Value

ABSTRAK Systemic Lupus Erythematosus (SLE) merupakan penyakit autoimun yang prevalensinya tiap tahun meningkat di dunia maupun di Indonesia. Kelelahan yang parah dapat menyebabkan kekambuhan pada pasien SLE. Kelelahan merupakan gejala yang paling melemahkan dan mengganggu fungsi fisik, sosial dan emosional. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang berhubungan dengan kelelahan pada pasien SLE di Yayasan Lupus Indonesia Panggon Kupu Semarang. Jenis penelitian ini adalah penelitian deskriptif analitik dengan rancangan penelitian cross sectional. Sampel penelitian adalah 30 pasien SLE yang diperoleh dengan menggunakan teknik Total Sampling. Analisis data dilakukan secara univariat dan bivariat. Hasil analisis bivariat menunjukan faktor yang berhubungan dengan kelelahan yaitu: tingkat keparahan penyakit (r value = 0,853, sig = 0,00) dan kualitas tidur (r value = 0,796, sig = 0,00), dan faktor yang tidak berhubungan yaitu aktivitas fisik (r value = -0,79). Hasil analisis multivariat menunjukan faktor yang paling dominan yang berhubungan dengan kelelahan yaitu kualitas tidur (p value = 0,043, exp (OR) = 16,500) memiliki probabilitas terhadap terjadinya kelelahan sebesar 61,89%. Kata Kunci: Kelelahan, SLE. Systemic Lupus Erythematosus ( SLE ) was an autoimmune disease whose prevalence was increasing every year in the world as well as in Indonesia. Severe fatigue can lead to relapse in patients with SLE. Fatigue was a symptom of the most debilitating and interfere with the functioning of physical, social and emotional. The objective of the study to know factors associated with fatigue in patients SLE at Indonesian Lupus Panggon Kupu Foundation in Semarang City. This research was descriptive analytic research with Cross Sectional design. The samples were 30 patients with SLE were obtained using total sampling technique. Data analysis was performed using univariate and bivariate. Bivariate analysis results showed that factors associated with fatigue were: the severity of disease (r value = 0,853, sig = 0,00) and sleep quality (r value = 0,796, sig = 0,00), while the factors that was not associated were: physical activity (r value = -0,79). Multivariate analysis showed that the most dominant factor associated to the fatigue was the quality of sleep (p value = 0,043, exp (OR) = 16,500) have the probability of the occurrence of fatigue by 61.89 %.  

scholarly journals Association between depression and sleep quality in patients with systemic lupus erythematosus: a systematic review and meta-analysis

2021 ◽  
Author(s):  
Rulan Yin ◽  
Lin Li ◽  
Lan Xu ◽  
Wenjie Sui ◽  
Mei’e Niu ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Sleep Quality ◽  
Lupus Erythematosus ◽  
Sleep Disturbances ◽  
Cochrane Library ◽  
Poor Sleep ◽  
Moderate Correlation ◽  
Systemic Lupus ◽  
Poor Sleep Quality ◽  
Subjective Sleep Quality

Abstract Background Currently, there is no consistent understanding of the relationship between depression and sleep quality in patients with systemic lupus erythematosus (SLE). This study aimed to explore the correlation between depression and sleep quality in SLE patients. Methods Five English (PubMed, Web of Science, EMBASE, Cochrane Library, and CINAHL) databases were systematically searched from inception to January 12, 2021. Two authors independently screened publications and extracted data according to set inclusion and exclusion criteria. Statistical analyses were performed with STATA 16.0. Data were pooled using a random-effects model. Results A total of 9 identified studies matched the inclusion criteria, reporting on 514 patients with SLE in the analysis. A moderate correlation of depression with sleep quality was found (pooled r = 0.580 [0.473, 0.670]). Compared to good sleepers, patients with SLE and poor sleep quality had higher levels of depression (standardized mean difference =  − 1.28 [− 1.87, − 0.69]). Depression was associated with subjective sleep quality (r = 0.332 [0.009, 0.592]), sleep latency (r = 0.412 [0.101, 0.649]), sleep disturbances (r = 0.405 [0.094, 0.645]), daytime dysfunction (r = 0.503 [0.214, 0.711]), the four dimensions of Pittsburgh Sleep Quality Index (PSQI), while no significant correlation was found in the other three PSQI dimensions. Conclusion Depression had a moderate correlation with sleep quality in patients with SLE. Patients with poor sleep quality tended to have higher level of depression than that of good sleepers. Awareness of the correlation may help rheumatology physicians and nurses to assess and prevent depression and improve sleep quality in patients with SLE.

scholarly journals POS1465-HPR THE RELATIONSHIP BETWEEN SEDENTARY BEHAVIOR AND SLEEP IN RHEUMATOID ARTHRITIS: A CROSS-SECTIONAL STUDY

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1017.2-1018
Author(s):  
N. Kelly ◽  
E. Hawkins ◽  
H. O’leary ◽  
K. Quinn ◽  
G. Murphy ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Physical Activity ◽  
Sleep Quality ◽  
Sedentary Behavior ◽  
Disease Duration ◽  
Cross Sectional Study ◽  
P Value ◽  
Poor Sleep ◽  
Cross Sectional ◽  
The Relationship

Background:Rheumatoid arthritis (RA) is a chronic, autoimmune inflammatory condition that affects 0.5% of the adult population worldwide (1). Sedentary behavior (SB) is any waking behavior characterized by an energy expenditure of ≤1.5 METs (metabolic equivalent) and a sitting or reclining posture, e.g. computer use (2) and has a negative impact on health in the RA population (3). Sleep is an important health behavior, but sleep quality is an issue for people living with RA (4, 5). Poor sleep quality is associated with low levels of physical activity in RA (4) however the association between SB and sleep in people who have RA has not been examined previously.Objectives:The aim of this study was to investigate the relationship between SB and sleep in people who have RA.Methods:A cross-sectional study was conducted. Patients were recruited from rheumatology clinics in a large acute public hospital serving a mix of urban and rural populations. Inclusion criteria were diagnosis of RA by a rheumatologist according to the American College of Rheumatology criteria age ≥ 18 and ≤ 80 years; ability to mobilize independently or aided by a stick; and to understand written and spoken English. Demographic data on age, gender, disease duration and medication were recorded. Pain and fatigue were measured by the Visual Analogue Scale (VAS), anxiety and depression were assessed using the Hospital Anxiety and Depression Scale (HADS), and sleep quality was assessed using the Pittsburgh Sleep Quality Index. SB was measured using the ActivPAL4™ activity monitor, over a 7-day wear period. Descriptive statistics were calculated to describe participant characteristics. Relationships between clinical characteristics and SB were examined using Pearson’s correlation coefficients and regression analyses.Results:N=76 participants enrolled in the study with valid data provided by N=72 participants. Mean age of participants was 61.5years (SD10.6) and the majority 63% (n = 47) were female. Participant mean disease duration was 17.8years (SD10.9). Mean SB time was 533.7 (SD100.1) minutes (8.9 hours per day/59.9% of waking hours). Mean sleep quality score was 7.2 (SD5.0) (Table 1). Correlation analysis and regression analysis found no significant correlation between sleep quality and SB variables. Regression analysis demonstrated positive statistical associations for SB time and body mass index (p-value=0.03846, R2 = 0.05143), SB time and pain VAS (p-value=0.009261, R2 = 0.07987), SB time and HADS (p-value = 0.009721, R2 = 0.08097) and SB time and HADSD (p-value = 0.01932, R2 = 0.0643).Conclusion:We found high levels of sedentary behavior and poor sleep quality in people who have RA, however no statistically significant relationship was found in this study. Future research should further explore the complex associations between sedentary behavior and sleep quality in people who have RA.References:[1]Carmona L, et al. Rheumatoid arthritis. Best Pract Res Clin Rheumatol 2010;24:733–745.[2]Anon. Letter to the editor: standardized use of the terms “sedentary” and “sedentary behaviours”. Appl Physiol Nutr Metab = Physiol Appl Nutr Metab 2012;37:540–542.[3]Fenton, S.A.M. et al. Sedentary behaviour is associated with increased long-term cardiovascular risk in patients with rheumatoid arthritis independently of moderate-to-vigorous physical activity. BMC Musculoskelet Disord 18, 131 (2017).[4]McKenna S, et al. Sleep and physical activity: a cross-sectional objective profile of people with rheumatoid arthritis. Rheumatol Int. 2018 May;38(5):845-853.[5]Grabovac, I., et al. 2018. Sleep quality in patients with rheumatoid arthritis and associations with pain, disability, disease duration, and activity. Journal of clinical medicine, 7(10)336.Table 1.Sleep quality in people who have RASleep variableBed Time N(%) before 10pm13(18%) 10pm-12pm43 (60%) after 12pm16 (22%)Hours Sleep mean(SD)6.56 (1.54)Fall Asleep minutes mean(SD)33.3(27.7)Night Waking N(%)45(63%)Self-Rate Sleep mean(SD)2.74 (0.90)Hours Sleep mean(SD)6.56 (1.54)Disclosure of Interests:None declared

The relationship of antiphospholipid antibodies to cognitive function in patients with systemic lupus erythematosus

1997 ◽  
Vol 3 (4) ◽  
pp. 377-386 ◽  
Author(s):  
SUSAN D. DENBURG ◽  
RAMONA M. CARBOTTE ◽  
JEFFREY S. GINSBERG ◽  
JUDAH A. DENBURG
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Verbal Memory ◽  
Lupus Anticoagulant ◽  
Cognitive Test ◽  
Antiphospholipid Antibody ◽  
Systemic Lupus ◽  
Cross Sectional ◽  
Antibody Positivity ◽  
The Relationship

Objective: To examine the relationship between antiphospholipid antibody positivity (expressed as the lupus anticoagulant) and cognitive dysfunction in patients with systemic lupus erythematosus (SLE). Methods: Cross-sectional comparisons of lupus anticoagulant (LA) positive (N = 39) and negative (N = 79) patients and controls (N = 35) on a cognitive test battery; 22 LA-positive and 53 LA-negative patients who had never experienced neuropsychiatric events (never-NP–SLE) were also compared separately. Results: LA-positive patients were 2 to 3 times more likely than were LA-negative patients to be designated as cognitively impaired. As a group, LA-positive patients, particularly those in the never-NP–SLE group, demonstrated lower performance primarily on tasks of verbal memory, cognitive flexibility, and psychomotor speed. Conclusions: LA positivity is associated with subclinical nervous system compromise, and a pattern of deficits compatible with subcortical involvement, possibly on the basis of ongoing LA-related microthrombotic events or vasculopathy. (JINS, 1997, 3, 377–386.)

scholarly journals Kejadian Hiperbilirubinemia Ditinjau dari Berat Badan Lahir

2020 ◽  
Vol 5 (1) ◽  
pp. 36-42
Author(s):  
Yeviza Puspitasari
Keyword(s):  
Random Sampling ◽  
Statistical Tests ◽  
Univariate Analysis ◽  
Bivariate Analysis ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Study Population ◽  
Relationship Of ◽  
The Relationship

Hyperbilirubinemia is one of the clinical phenomena most often found in neonates occurring in the first week of life, which is also one of the factors causing infant death is influenced by the immature liver function of the baby to process erythrocytes (red blood cells), resulting in the accumulation of bilirubin. The purpose of this study was to determine the relationship of birth weight of infants with the incidence of hyperbilirubinemia in RSUD dr. Ibnu Soetowo Baturaja Ogan Komering Ulu Regency in 2019. This study uses analytic methods with a cross-sectional approach. The study population was all infants aged 0-7 days in the neonatal room at RSUD dr. Ibnu Soetowo Baturaja Ogan Komering Ulu Regency in 2019, with a random sampling. Data analysis uses univariate analysis and bivariate analysis using distribution tables and Chi-Square statistical tests, with a 95% confidence level. In the univariate analysis, of 203 respondents found 26.5% had hyperbilirubinemia and those without hyperbilirubinemia 72.5%, 24.6% of infants with LBW and non-LBW infants 75.4%. Bivariate analysis showed that there was an LBW relationship with the incidence of hyperbilirubinemia (p-value 0,000).

scholarly journals Hubungan Derajat Aktivitas Penyakit Lupus Eritematosus Sistemik Berdasarkan Skor Mex-Sledai Dengan Kejadian Anemia Pada Penderita Lupus Eritematosus Sistemik Di Komunitas Odapus Lampung

2021 ◽  
Vol 3 (2) ◽  
pp. 192-202
Author(s):  
Rina Kirwiastiny ◽  
Ringgo Alfarisi ◽  
Hidayat Hidayat ◽  
Ageel Al-Aziz Marjaen
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Chronic Disease ◽  
Lupus Erythematosus ◽  
Deficiency Anemia ◽  
P Value ◽  
Systemic Lupus Erythematous ◽  
Systemic Lupus ◽  
Immune Disease ◽  
Cross Sectional ◽  
Sledai Score

ABSTRACT : RELATIONSHIP OF SYSTEMIC LUPUS ERYTHEMATOSUS ACTIVITIES BASED ON MEX-SLEDAI SCORE WITH INCIDENCE OF ANEMIA IN SYSTEMIC LUPUS ERYTHEMATOUS PATIENTS IN THE ODAPUS LAMPUNG COMMUNITY, 2020Background : Systemic Lupus Erytematosus (SLE) is a complex autoimmune disease characterized by the presence of autoantibodies against the cell nucleus and involving many organ systems in the body. Anemia in LES patients varies between chronic disease anemia, hemolytic anemia, blood loss, renal insufficiency, infection, myelodysplasia, and aplastic anemia. What often occurs in LES anemia is due to erythropoesis suppression due to chronic inflammation. Anemia in LES patients is an immune or non-immune disease. Anemia is a non-immune disease is anemia in chronic disease, iron deficiency anemia, sideroblastic anemia, anemia in kidney disease, anemia indicated by drugs, and anemia secondary to other diseases (eg sickle cell anemia).Research purposes : This study was to determine the degree of activity of systemic lupus erythematosus based on max-sledai and hemoglobin levels in systemic lupus erythematous patients in the ODAPUS Lampung community in 2020.Methode :The analytical observational method was used using a cross sectional approach. The research subjects were 30 respondents who used the total sampling technique from members of the ODAPUS Lampung community by conducting MEX-SLEDAI interviews and blood sampling conducted from November 2019 to February 2020. Statistical test used Fisher exact test.Results: From 30 study subjects, disease activity based on MEX-SLEDAI was above the average of 21 patients (70%). And the results of blood tests were 18 patients (60%) who were not anemia and 12 patients (40%) had anemia.Conclusion     : There was a significant relationship between the degree of activity of Systemic Lupus Erythematosus based on the MEX-SLEDAI score and the incidence of anemia with p value = 0.024 meaning the p value ≤ 0.05. Keywords      : LES; Incidence of Anemia; MEX-SLEDAI    INTISARI : HUBUNGAN DERAJAT AKTIVITAS PENYAKIT LUPUS ERITEMATOSUS SISTEMIK BERDASARKAN SKOR  MEXSLEDAI DENGAN KEJADIAN ANEMIA PADA PENDERITA LUPUS ERITEMATOUS SISTEMIK DI KOMUNITAS ODAPUS LAMPUNG  Latar belakang : Systemic Lupus Erytematosus (SLE) merupakan penyakit autoimun yang kompleks ditandai oleh adanya autoantibodi terhadap inti sel dan melibatkan banyak sistem organ dalam tubuh. Anemia pada pasien LES bervariasi antara anemia penyakit kronis, anemia hemolitik, kehilangan darah, insufisiensi ginjal, infeksi, mielodisplasia, dan anemia aplastik. Yang sering terjadi anemia pada LES disebabkan supresi eritropoesis karena inflamasi yang kronis.  Anemia pada pasien LES merupakan penyakit imun atau non-imun. Anemia merupakan penyakit non-imun adalah anemia pada penyakit kronik ,anemia defisiensi besi, anemia sideroblastik, anemia pada penyakit ginjal, anemia indikasi obat, dan anemia sekunder terhadap penyakit lain ( misalnya anemia sel sabit ).Tujuan Penelitian : Penelitian ini untuk mengetahui hubungan drajat aktivitas penyakit lupus eritematosus sistemik berdasarkan max-sledai dengan kadar hemoglobin pada penderita lupus eritematous sistemik di komunitas ODAPUS lampung tahun 2020.Metode : Digunakan metode observasional analitik menggunakan pendekatan cross sectional. Subjek penelitian sebanyak 30 responden yang menggunakan teknik total sampling dari anggota komunitas ODAPUS Lampung dengan melakukan wawancara MEX-SLEDAI dan pengambilan sampel darah yang dilakukan pada bulan November 2019 s/d Februari 2020. Uji statistic menggunakan Fisher exact test.Hasil : Dari 30 subjek penelitian didapatkan aktifitas penyakit berdasarkan MEX-SLEDAI di atas rata – rata sebanyak 21 pasien (70%). Dan hasil peneriksaan darah yaitu 18 pasien (60%) yang Tidak anemia dan yang mengalami Anemia ada 12 pasien (40%).Kesimpulan   : Terdapat hubungan bermakna antara derajat aktivitas penyakit Lupus Eritematosus Sistemik berdasarkan skor MEX-SLEDAI dengan Kejadian Anemia dengan p value =0.024 berarti nilai p value ≤ 0.05. Kata Kunci     : LES; Kejadian Anemia; MEX-SLEDAI

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