COMPARISON OF THE ACTION OF GROWTH HORMONE, HUMAN CHORIONIC GONADOTROPHIN AND AN ANABOLIC STEROID IN HYPOPHYSECTOMIZED RATS
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ABSTRACT Human chorionic gonadotrophin (HCG) and an anabolic steroid did not raise the weight of hypophysectomized rats: those substances, however, prevented the weight decrease seen in the first 3 weeks after operation of 200 g rats which were maintained both pre- and post-operatively on the same routine diet. HCG did not have this effect on hypophysectomized animals which had been also castrated. It is assumed that the growth promoting action seen after HCG or anabolic steroid is due in normal animals and patients to an endogenous stimulation of growth hormone production by the pituitary anterior lobe.
1985 ◽
Vol 38
(4)
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pp. 445
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1957 ◽
Vol 105
(4)
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pp. 335-360
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