Relationship of lipid parameters and insulin resistance with bone health in South Korean adolescents

2015 ◽  
Author(s):  
Do-Hoon Kim ◽  
Sang-Woon Park ◽  
Dong-Wook Jung ◽  
Su-Jung Yoon ◽  
Kyungdo Han ◽  
...  
2015 ◽  
Vol 27 (2) ◽  
pp. 635-642 ◽  
Author(s):  
S.-W. Park ◽  
G.-E. Nam ◽  
D.-W. Jung ◽  
S.-J. Yoon ◽  
K. Han ◽  
...  

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Philip Mellen ◽  
Angela Liese ◽  
Steven Haffner ◽  
David Goff

Context: Whole grain intake is inversely associated with LDL-c and the metabolic syndrome, but the relationship of whole grains with other lipid parameters, such as small, dense LDL, is not established. We sought to evaluate the relationship of whole grain intake with lipids, apolipoproteins, and LDL lipoprotein subclasses in a large, multi-ethnic cohort. Methods: This cross-sectional study evaluated 975 non-diabetic participants in the Insulin Resistance Atherosclerosis Study. Baseline whole grain intake was estimated based on intake of dark breads, cooked cereals, and high-fiber cereals assessed in a validated food frequency questionnaire. Fasting lipid measurements included apolipoproteins and lipoprotein subclasses quantified by NMR spectroscopy. Linear regression models evaluated lipid parameters across quartile of whole grain intake after adjustment for demographics (age, sex, ethnicity, center), anthropometrics (BMI, waist circumference), lifestyle factors (smoking, alcohol intake), dietary factors (total kcal, fruits, vegetables, dietary fats) and lipid-lowering medication use. Additional models included directly measured insulin sensitivity (Si). Results: The cohort was 56% female, had a mean (SD) age of 54.8 (8.5) years, and was 60% non-white, with a median whole grain intake of .73 servings/day. In adjusted models, there was an inverse association between whole grain intake and LDL-c, Apo-B, Apo-B/Apo-A1 ratio, LDL particle concentration (LDL-p), and small LDL-p (Table ). These associations remained significant after adjustment for Si (LDL-c: p=.007; Apo-B: p=.04; Apo-B/Apo-A1: p=.03; LDL-p: p=.03; small LDL-p: p=.03). Conclusion: Whole grain intake is inversely associated with multiple lipid risk factors, including total and small LDL particle concentration, independent of insulin sensitivity and other confounders. This demonstrates additional mechanisms for the cardioprotective effects of whole grains.


Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1812-P
Author(s):  
MARIA D. HURTADO ◽  
J.D. ADAMS ◽  
MARCELLO C. LAURENTI ◽  
CHIARA DALLA MAN ◽  
CLAUDIO COBELLI ◽  
...  

Medicine ◽  
2017 ◽  
Vol 96 (51) ◽  
pp. e9403 ◽  
Author(s):  
Dong-Wook Jung ◽  
Joo-Hyun Park ◽  
Do-Hoon Kim ◽  
Moonyoung Choi ◽  
Shinhye Kim ◽  
...  

2011 ◽  
Vol 31 (5) ◽  
pp. 1208-1214 ◽  
Author(s):  
Sander J. Robins ◽  
Asya Lyass ◽  
Justin P. Zachariah ◽  
Joseph M. Massaro ◽  
Ramachandran S. Vasan

Author(s):  
Dae-Jung Lee ◽  
Wi-Young So ◽  
Seung-Man Lee

This study was aimed at providing practical information to improve Korean adolescents’ wellness by empirically identifying its correlation with sports participation and having an internal health locus of control (IHLC) during the COVID-19 pandemic. This study comprised both a pilot test and a main study. We recruited 844 Korean adolescents as subjects in January 2021 to participate in an online self-reported survey. The reliability and validity of the scales used (sports participation, IHLC, and wellness) were verified through a pilot test. In the main study, we verified the differences between all variables according to adolescents’ demographic characteristics and the structural relationship of sports participation, IHLC, and wellness. Sports participation had a positive effect on IHLC (p < 0.001) and wellness (p < 0.001). Additionally, IHLC had a positive effect on wellness (p < 0.001). In juvenile educational institutions, there is a need to develop strategies to increase wellness, sports participation, and IHLC among adolescent students, which can improve their wellness in the context of the COVID-19 pandemic.


Hypertension ◽  
2016 ◽  
Vol 68 (suppl_1) ◽  
Author(s):  
Allison Jasti ◽  
Deborah L Stewart ◽  
Gregory A Harshfield

Background: The skeleton is vital to sodium homeostasis, accounting for 40% of the body’s sodium. Research indicates stress and low sodium intake are independently associated with RAAS activation. In certain populations, stress can induce salt sensitivity, increasing the risk of hypertension and target organ damage, but the association of low versus high sodium intake with bone health is controversial. Purpose: This study sought out the relationship of low sodium and stress-induced RAAS activation with bone health. The tested hypothesis was those with lowest sodium intake would have lower total bone mineral density (TBMD) and content (TBMC) associated with stress-induced increases in angiotensin ii (Ang II) and aldosterone (Aldo). Methods: We compared effect of stress on Ang II, Aldo, TBMD and TMBC in healthy Caucasian and African-American adolescents. Subjects were grouped by quartiles based on sodium intake, assessed by urinary sodium excretion. Results: Due to females, overall significant inverse associations are observed between TBMD, TBMC, Ang II and Aldo in the lowest sodium intake quartile. Post-stress, women in the lowest sodium intake quartile showed that increases in both Ang II and Aldo correspond with lower TMBC and TMBD. There was no significance between Ang II, Aldo, TMBC and TMBD in the three highest quartiles of women nor in any male quartile. Conclusion: These data suggest Ang II and Aldo may reduce TMBC and TMBD in women. Stress-induced increases in Ang II and Aldo, with low sodium intake, may further reduce TBMD and TBMC in women. Ang II inhibition and/or moderated salt intake may be an efficacious prevention or treatment against the development of osteoporosis.


2009 ◽  
Vol 66 (3) ◽  
pp. 346-349 ◽  
Author(s):  
Elvira Verduci ◽  
Silvia Scaglioni ◽  
Carlo Agostoni ◽  
Giovanni Radaelli ◽  
Marialuisa Biondi ◽  
...  

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