Real-time sonoelastography and ultrasound evaluation of Achilles tendon of diabetic patients

2015 ◽  
Author(s):  
Berna Evranos ◽  
Ilkay Idilman ◽  
Ali Ipek ◽  
Sefika Burcak Polat ◽  
Bekir Cakir ◽  
...  
Author(s):  
Rumi Tanaka ◽  
Kimie Fujita ◽  
Satoko Maeno ◽  
Kanako Yakushiji ◽  
Satomi Tanaka ◽  
...  

2021 ◽  
Vol 94 (1121) ◽  
pp. 20200173
Author(s):  
Shamrendra Narayan ◽  
Amit Goel ◽  
Ajai Kumar Singh ◽  
Anup Kumar Thacker ◽  
Neha Singh ◽  
...  

Objectives: The aim of this observational study was ultrasound evaluation of peripheral nerves cross-sectional area (CSA) in subjects with probable diabetic peripheral sensorimotor neuropathy (DPN). CSA was analyzed with reference to clinical and nerve conduction study’s (NCS) parameters for early diagnosis and pattern of involvement. Methods: A total of 50 patients with probable DPN due to Type 2 diabetes and 50 age-matched healthy controls underwent sonographic examinations of ulnar nerve at the lower arm, median nerve proximal to carpal tunnel, the common peroneal nerve proximal to fibular head, tibial nerve proximal to the tarsal tunnel, and sural nerve at lower third leg. Results: CSA was increased in cases of DPN as compared to healthy controls. Area changes were more marked with demyelinating pattern. Probable DPN cases with normal NCS had significantly higher number of peripheral nerves showing increased CSA as compared to healthy control. A cut-off of >4 nerve thickening showed a sensitivity of 86 %, and specificity of 56%. The neuropathy pattern in the lower limb was axonal, whereas in the upper limb, it was demyelinating with the majority showing sonographic feature of associated compressive neuropathy. Conclusion: There is an increase in CSA of peripheral nerve in diabetic patients. It can be used as a morphological marker for classifying DPN with changes being picked up earlier to NCS abnormality. Clinical neurological presentation in probable DPN can also be due to compressive neuropathy in early phases, and ultrasound can be a useful tool. Advances in knowledge: Early pick up of DPN cases shall be useful for early therapy and motivating the patients to actively participate in the treatment. Morphological changes on ultrasonography precedes the electrodiagnostic change in DPN. Symptoms of DPN is not only due to metabolic changes but also compressive neuropathy.


2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Vineeta Singh ◽  
Atul Kumar Gupta ◽  
S. P. Singh ◽  
Anil Kumar

Cinnamomum tamalaNees & Eberm. is an important traditional medicinal plant, mentioned in various ancient literatures such as Ayurveda. Several of its medicinal properties have recently been proved. To characterize diversity in terms of metabolite profiles ofCinnamomum tamalaNees and Eberm genotypes, a newly emerging mass spectral ionization technique direct time in real time (DART) is very helpful. The DART ion source has been used to analyze an extremely wide range of phytochemicals present in leaves ofCinnamomum tamala. Ten genotypes were assessed for the presence of different phytochemicals. Phytochemical analysis showed the presence of mainly terpenes and phenols. These constituents vary in the different genotypes ofCinnamomum tamala. Principal component analysis has also been employed to analyze the DART data of theseCinnamomumgenotypes. The result shows that the genotype ofCinnamomum tamalacould be differentiated using DART MS data. The active components present inCinnamomum tamalamay be contributing significantly to high amount of antioxidant property of leaves and, in turn, conditional effects for diabetic patients.


2018 ◽  
Vol 20 (2) ◽  
pp. 190-196 ◽  
Author(s):  
Elmer Jeto Gomes Ataide ◽  
Rajesh Kumar Sinha ◽  
G. Arun Maiya

Diabetes occurs when the pancreas in the human body does not secrete sufficient insulin. It is a disease that is growing rapidly and affecting many lives. Hence, it needs constant monitoring. Wearable devices are those devices that are present on your person at all times. If the monitoring of this disease could be paired with wearable devices along with enabling real-time documentation in the patients’ medical records, it would benefit both the caregivers and the patients by saving time, money, effort and the amount of work put in by both during the health care process, hence, aiding in the delivery of quality health care. This article deals with identifying the existing wearable devices in detecting diabetes or risk of diabetes non-invasively and further scope of research in the respective area.


2014 ◽  
Vol 24 (7) ◽  
pp. 2124-2132 ◽  
Author(s):  
A. Busilacchi ◽  
M. Olivieri ◽  
S. Ulisse ◽  
R. Gesuita ◽  
E. Skrami ◽  
...  

2016 ◽  
Vol 120 (2) ◽  
pp. 130-137 ◽  
Author(s):  
Christian Couppé ◽  
Rene Brüggebusch Svensson ◽  
Mads Kongsgaard ◽  
Vuokko Kovanen ◽  
Jean-Francois Grosset ◽  
...  

Diabetic patients have an increased risk of foot ulcers, and glycation of collagen may increase tissue stiffness. We hypothesized that the level of glycemic control (glycation) may affect Achilles tendon stiffness, which can influence gait pattern. We therefore investigated the relationship between collagen glycation, Achilles tendon stiffness parameters, and plantar pressure in poorly ( n = 22) and well ( n = 22) controlled diabetic patients, including healthy age-matched (45–70 yr) controls ( n = 11). There were no differences in any of the outcome parameters (collagen cross-linking or tendon stiffness) between patients with well-controlled and poorly controlled diabetes. The overall effect of diabetes was explored by collapsing the diabetes groups (DB) compared with the controls. Skin collagen cross-linking lysylpyridinoline, hydroxylysylpyridinoline (136%, 80%, P < 0.01) and pentosidine concentrations (55%, P < 0.05) were markedly greater in DB. Furthermore, Achilles tendon material stiffness was higher in DB (54%, P < 0.01). Notably, DB also demonstrated higher forefoot/rearfoot peak-plantar-pressure ratio (33%, P < 0.01). Overall, Achilles tendon material stiffness and skin connective tissue cross-linking were greater in diabetic patients compared with controls. The higher foot pressure indicates that material stiffness of tendon and other tissue (e.g., skin and joint capsule) may influence foot gait. The difference in foot pressure distribution may contribute to the development of foot ulcers in diabetic patients.


1985 ◽  
Vol 23 (1) ◽  
pp. 233 ◽  
Author(s):  
K.M. Thayer ◽  
D.W. Forrest ◽  
T.H. Welsh

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