Gender-specific prevalence of hyperuricemia and association with metabolic disorders in China: a hospital population based retrospective real-world study

2021 ◽  
Author(s):  
Shuguang Pang ◽  
Qiang Jiang ◽  
Sun Pei ◽  
Yi Li ◽  
Yanhua Zhu ◽  
...  
Keyword(s):  
Real World ◽  
Metabolic Disorders ◽  
Population Based ◽  
Hospital Population ◽  
Gender Specific

scholarly journals A comparative study of teriflunomide and dimethyl fumarate within the Swedish MS Registry

2021 ◽  
pp. 135245852110196
Author(s):  
Jan Hillert ◽  
Jon A Tsai ◽  
Mona Nouhi ◽  
Anna Glaser ◽  
Tim Spelman
Keyword(s):  
Multiple Sclerosis ◽  
Real World ◽  
Clinical Effectiveness ◽  
Dimethyl Fumarate ◽  
Population Based ◽  
Life Outcomes ◽  
Treatment Persistence ◽  
Relapsing Remitting ◽  
Relapsing Remitting Multiple Sclerosis

Background: Teriflunomide and dimethyl fumarate (DMF) are first-line disease-modifying treatments for multiple sclerosis with similar labels that are used in comparable populations. Objectives: The objective of this study was to compare the effectiveness and persistence of teriflunomide and DMF in a Swedish real-world setting. Methods: All relapsing-remitting multiple sclerosis (RRMS) patients in the Swedish MS registry initiating teriflunomide or DMF were included in the analysis. The primary endpoint was treatment persistence. Propensity score matching was used to adjust comparisons for baseline confounders. Results: A total of 353 teriflunomide patients were successfully matched to 353 DMF. There was no difference in the rate of overall treatment discontinuation by treatment group across the entire observation period (hazard ratio (HR) = 1.12; 95% confidence interval (CI) = 0.91–1.39; p = 0.277; reference = teriflunomide). Annualised relapse rate (ARR) was comparable ( p = 0.237) between DMF (0.07; 95% CI = 0.05–0.10) and teriflunomide (0.09; 95% CI = 0.07–0.12). There was no difference in time to first on-treatment relapse (HR = 0.78; 95% CI = 0.50–1.21), disability progression (HR = 0.55; 95% CI = 0.27–1.12) or confirmed improvement (HR = 1.17; 95% CI = 0.57–2.36). Conclusion: This population-based real-world study reports similarities in treatment persistence, clinical effectiveness and quality of life outcomes between teriflunomide and dimethyl fumarate.

scholarly journals Real-world Outcomes of First-line Anti-PD-1 Therapy for Advanced Melanoma: A Nationwide Population-based Study

2020 ◽  
Vol 43 (8) ◽  
pp. 256-264
Author(s):  
Michiel C.T. van Zeijl ◽  
John B.A.G. Haanen ◽  
Michel W.J.M. Wouters ◽  
Liesbeth C. de Wreede ◽  
Anouk Jochems ◽  
...  
Keyword(s):  
Real World ◽  
Population Based ◽  
Advanced Melanoma ◽  
First Line ◽  
Population Based Study

scholarly journals Predictors of disordered eating in adolescence and young adulthood

2013 ◽  
Vol 38 (2) ◽  
pp. 128-138 ◽  
Author(s):  
Dawit Shawel Abebe ◽  
Leila Torgersen ◽  
Lars Lien ◽  
Gertrud S. Hafstad ◽  
Tilmann von Soest
Keyword(s):  
Risk Factors ◽  
Disordered Eating ◽  
Young Adulthood ◽  
Early Adolescence ◽  
Developmental Psychopathology ◽  
Population Based ◽  
Specific Risk ◽  
Random Intercept ◽  
Developmental Phases ◽  
Gender Specific

We investigated longitudinal predictors for disordered eating from early adolescence to young adulthood (12–34 years) across gender and different developmental phases among Norwegian young people. Survey data from a population-based sample were collected at four time points (T) over a 13-year time span. A population-based sample of 5,679 females and males at T1 and T2, 2,745 at T3 and 2,718 at T4 were included in analyses, and linear regression and random intercept models were applied. In adolescence, initial disordered eating and parental overprotectiveness were more strongly related to disordered eating among females, whereas loneliness was a stronger predictor for adolescent males. Initial disordered eating during early adolescence predicted later disordered eating more strongly in late- than mid-adolescence. In young adulthood, no significant gender-specific risk factors were found. The findings provide support for both shared and specific risk factors for the developmental psychopathology of disordered eating.

scholarly journals Gender-specific physical activity-related injuries and risk factors among university students in China: a multicentre population-based cross-sectional study

BMJ Open ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. e040865
Author(s):  
Weicong Cai ◽  
Shangmin Chen ◽  
Liping Li ◽  
Pengying Yue ◽  
Xiaofan Yu ◽  
...  
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
University Students ◽  
Leisure Time ◽  
Population Based ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
The Past ◽  
Chinese University ◽  
Gender Specific

ObjectivesData on the problem of physical activity-related injury (PARI) in university students and the risk factors for PARI among different genders are rare. We conducted a multicentre population-based study to investigate the occurrence of PARI and to explore the gender-specific risk factors for PARI among Chinese university students.DesignCross-sectional study.ParticipantsA total of 5341 students in grades 1–3 at eight universities in four Chinese cities were selected to complete the online questionnaires during March and April 2017. The questionnaires assessed sociodemographic characteristics, physical activity PA) involvement, sleep duration, sedentary behaviour and PARI experiences in the past 12 months.Main outcome measuresPARI during the past 12 months.ResultsAmong the 5341 participants, 1293 suffered from at least one PARI in the past 12 months, with an overall incidence rate of 24.2% (males: 26.2%, females: 23.2%) and an injury risk of 0.38 injuries/student/year (males: 0.48, females: 0.32). Over half of the injured (57.3%) experienced a withdrawal time of PA and nearly two-fifths (39.6%) required medical attention. Irrespective of gender, Shantou and Xi’an students, sports team members and those who engaged in sports and leisure-time vigorous-intensity PA (VPA) at a higher frequency were more likely to suffer from PARI. Male students who participated in sports and leisure-time VPA for long durations had a greater likelihood of sustaining PARI, while having a chronic condition and being involved in sports and leisure-time moderate-intensity PA at a higher frequency and longer duration were potential contributors to PARI among females.ConclusionsThe occurrence of PARI and its risk factors differed by gender, which provides a direction towards developing targeted and effective gender-specific preventative programmes to protect Chinese university students from PARI.

scholarly journals The Influence of Constipation on Asthma: A Real‐world, Population‐based Cohort Study

2021 ◽  
Author(s):  
Yen‐Chu Huang ◽  
Meng‐Che Wu ◽  
Yu‐Hsun Wang ◽  
James Cheng‐Chung Wei
Keyword(s):  
Cohort Study ◽  
Real World ◽  
Population Based ◽  
World Population

FOUR-SITE SKINFOLDS THICKNESS PERCENTILES of SCHOOLCHILDREN and ADOLESCENTS in TURKEY

2021 ◽  
pp. 1-28
Author(s):  
Meltem Soylu ◽  
Nazlı Şensoy ◽  
İsmet Doğan ◽  
Nurhan Doğan ◽  
Mümtaz M. Mazicioğlu ◽  
...  
Keyword(s):  
Body Fat ◽  
Skinfold Thickness ◽  
Population Based ◽  
Specific Reference ◽  
Fat Percentage ◽  
Cross Sectional ◽  
Lms Method ◽  
And Gender ◽  
Thickness Measurements ◽  
Gender Specific

Abstract Objective: The primary purpose of this study was to establish Turkish smoothed centile charts and LMS tables for four-site skinfold thickness based on a population-based sample and secondary purpose was to elaborate a reference for the percentage of body fat. Design: A cross-sectional and descriptive study was conducted between January and May 2017. Triceps, biceps and subscapular, suprailiac skinfold thickness were measured using Holtain skinfold caliper. Age and gender specific percentile values were determined with the LMS method, and body fat percentage was calculated using the Westrate and Deurenberg equation. Setting: Afyonkarahisar province in Turkey. Participants: This study was conducted on 4565, 6-18 years old students. Results: The triceps, biceps, and subscapular skinfolds of the girls were higher than the boys. From the age of seven, the sum of four skinfold thicknesses of the girls was more than those of the boys. This difference became more evident after the age of 12. Although fat percentages of girls showed a fluctuating change, it decreased with the age in boys. Westrate and Deurenberg equation fat percentages of girls until adolescence were lower than boys, but increased after 12 years of age and exceeded that of boys. Conclusions: This study has provided sex and age specific reference values for skinfold thickness, and has shown that obesity in girls is higher than in boys in schoolchildren in Afyonkarahisar. This study has also shown that skinfold thickness measurements are a valuable tool for screening obesity in children.

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