scholarly journals Clinical profile of fungal sepsis in new born: a tertiary centre experience from Bangladesh

2020 ◽  
Vol 10 (6) ◽  
pp. 170-173
Author(s):  
Farhana Tasneem ◽  
Mohammad Monir Hossain ◽  
Salahuddin Mahmud ◽  
Syed Shafi Ahmed
Keyword(s):  
Risk Factors ◽  
Overall Survival ◽  
Intensive Care ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Study Group ◽  
Ventilator Support ◽  
Study Population ◽  
Feed Intolerance ◽  
Neonatal Candidiasis

Background: Candida infections are frequent and major causes of septicemia in neonatal intensive care units and are associated with high morbidity and mortality. Low birth weight preterm infants are especially vulnerable to these devastating infections. Material and methods: A prospective observational study was done from May 2013 to June 2014 in SCABU (Special Care Baby Unit) & ICU (Intensive Care Unit) of Dhaka Shishu (Children) Hospital, Dhaka. All neonates admitted with suspected clinical sepsis were analyzed in the study. Among which 30 culture positive candida cases were identified and included in this study. Outcome measures assessed was the incidence of candidemia in our NICU with clinical profiles and associated risk factors. Results: Out of 30 newborns 18 (60%) were preterms, 20% of study population were having a birth weight of <1 kg, 23.3% with a birth weight of 1-1.5 kg and 23.3% with a birth weight of 1.5-2.5 kg. 73.4% of the study population were hospitalized for >1 week. In the study group 56.7% had feed intolerance, 53.3% needed ventilator support, 56.7% had temperature instability, 73.3% had thrombocytopenia 63.3% had apnea and 73.3% had jaundice. The overall survival was 63.3%. Conclusions Low birth weight, prematurity, use of broad spectrum antibiotics, mechanical ventilation and prolonged hospital stay were important risk factors associated with neonatal candidiasis in this study. Thrombocytopenia, feed intolerance, increased requirement for ventilator support, temperature instability, jaundice and apnea were significant clinical parameters noted in babies with culture proven neonatal candidiasis. The overall survival was 63.3% in the study group.

scholarly journals Clinical profile of neonatal candidiasis in newborn nursery

2018 ◽  
Vol 5 (2) ◽  
pp. 334
Author(s):  
Mary James ◽  
Anuja J. S. ◽  
Praveen Jacob Ninan
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Clinical Profile ◽  
High Morbidity ◽  
Ventilator Support ◽  
Temperature Instability ◽  
Increased Risk ◽  
Study Population ◽  
Feed Intolerance ◽  
Candida Infections

Background: Candidiasis refers to infection with fungi of the genus candida. Candida infections are frequent and major causes of septicemia in neonatal intensive care units and are associated with high morbidity and mortality. Low birth weight preterm infants are especially vulnerable to these devastating infections. Candida infections are a major cause of septicemia in neonatal ICUs and may affect 1.6% to 12.9% of very low birth weight infants. The smaller the infant is, the greater is the likelihood for systemic fungal infection to develop.Methods: 40 Newborns with culture proven candidiasis admitted in new-born nursery of Government T. D Medical College, Alappuzha, were selected for the study. The significance of different parameters such as gender, gestational age, birth weight, Apgar score, duration of hospital stays, central venous catheter and use of third generation cephalosporins were analysed. Clinical profile like apnoea, feed intolerance, requirement of ventilator support, temperature instability, thrombocytopenia, hyperglycemia etc. were analyzed.Results: Out of 40 newborns 39 were preterms, 42% of study population were having a birth weight of 1-1.5 kg, 33% with a birth weight of 1.5-2 kg and 20% with a birth weight of <1 kg.75% of the study population were hospitalized for >1 week. In the study group 58% had feed intolerance, 52.5% needed ventilator support, 52.5% had temperature instability, 70% had thrombocytopenia 50% had apnea and 4% had hyperglycemia. The overall survival was 60%.Conclusions: Prematurity, low birth weight and prolonged hospital stay were associated with increased risk of candidiasis. Feed intolerance, increased need for ventilator support, apnea, temperature instability and thrombocytopenia were significant clinical parameters. 

The Prevalence and Relationship between Periodontal Disease and Pre-term Low Birth Weight Infants at King Khalid University Hospital in Riyadh, Saudi Arabia

2004 ◽  
Vol 5 (2) ◽  
pp. 40-56 ◽  
Author(s):  
Sameer Abdullah Mokeem ◽  
Ghadeer Nabeel Molla ◽  
Thikriat Saleh Al-Jewair
Keyword(s):  
Risk Factors ◽  
Saudi Arabia ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Periodontal Disease ◽  
University Hospital ◽  
Low Birth Weight Infants ◽  
Study Population ◽  
Associated Risk Factors ◽  
Periodontal Indices

Abstract The aim of this study was to examine the prevalence and relationship between periodontal disease and preterm low birth weight (PLBW) among Saudi mothers at King Khalid University Hospital (KKUH) in Riyadh, Saudi Arabia. The periodontal status and the relative risk were also analyzed. The study consisted of 30 cases [infants <37 weeks and/or weighing ≥2.500 kilograms (kg)] and a daily random sample of 60 controls [≥37 weeks and/or weighing >2.500 kg]. Clinical periodontal indices were measured on the labor wards. Associated risk factors for periodontal disease and PLBW were ascertained by means of a structured questionnaire and maternal notes. The prevalence of the PLBW was found to be 11.3%, and the prevalence of periodontal disease was high among the study population. The risk of PLBW remained high with increasing periodontal disease (odds ratio [OR] 4.21, 95% confident interval [CI] 1.99-8.93) despite controlling the other risk factors such as age, smoking, and social class. In conclusion, there is a correlation between periodontal disease and PLBW in KKUH. Citation Mokeem SA, Molla GN, Al-Jewair TS. The Prevalence and Relationship between Periodontal Disease and Pre-term Low Birth Weight Infants at King Khalid University Hospital in Riyadh, Saudi Arabia. J Contemp Dent Pract 2004 May;(5)2:040-056.

scholarly journals Retinopathy of prematurity- clinical profile on incidence, risk factors and outcome

2020 ◽  
Vol 7 (11) ◽  
pp. 2189
Author(s):  
Purva Shah ◽  
Ketan Gadhvi ◽  
Bharat Muliya
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Neonatal Intensive Care Unit ◽  
Retinopathy Of Prematurity ◽  
Neonatal Intensive Care ◽  
Tertiary Hospital ◽  
Antenatal Steroids

Background: Retinopathy of prematurity is one of the important causes of preventable blindness in the world. Thereby timely screening, diagnosis and hence treatment is of utmost importance.Methods: This study was done in the neonatal intensive care unit of tertiary hospital, Surendranagar. Study design being observational, data collected from clinical examination and records of the preterm babies <34 weeks and low birth weight babies <1.5 kg and further screened them for retinopathy of prematurity. The incidence of ROP in the neonatal intensive care unit (NICU), risk factors which predispose to ROP (Retinopathy of prematurity) and outcome of these cases were analysed.Results: As per this study, ROP was found to be more common in <30 weeks gestation and<1 kg neonate, and found to be associated with oxygen exposure, blood product use, antenatal steroids and surfactant.Conclusions: The analysis of the incidence and risk factors, will henceforth help in identifying and acting on time, thereby improving overall outcome of the preterm and low birth weight new-borns.

Risk factors for feed intolerance in very low birth weight infants

2021 ◽  
Vol 11 (4) ◽  
pp. 167
Author(s):  
Satish Saluja ◽  
Anurag Fursule ◽  
Manoj Modi ◽  
Arun Soni
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Very Low Birth Weight ◽  
Low Birth Weight Infants ◽  
Feed Intolerance

scholarly journals Admission Hypothermia Among Neonates Presented to Neonatal Intensive Care Unit

2013 ◽  
Vol 33 (3) ◽  
pp. 166-171 ◽  
Author(s):  
Shaheen Akter ◽  
Rubiya Parvin ◽  
B.H. Nazma Yasmeen
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Long Distance ◽  
Normal Delivery ◽  
Neonatal Hypothermia

Introduction: In developing countries, thermal protection of the newborn is not properly addressed. Neonates presented to Neonatal intensive care unit (NICU) for admission with various problems are frequently found to be hypothermic. The objective of this study was to determine the incidence and associated risk factors for neonatal hypothermia on admission to NICU. Materials and Methods: This was a prospective observational study carried over a period of three years at Enam Medical College and Hospital (EMCH) among the newborns admitted to NICU. Hypothermia has been defined as axillary temperature <36.5°C (<97.7° F). Temperature was measured at admission. Data were collected regarding perinatal and socio economic factors. Bivariate and multivariate analysis has been done to see the association of risk factors. Result: A total of 2310 babies between 0 and 680 h of age (mean 43± 12 hours) were studied. Thirty four percent (785) of the neonates had hypothermia. Mean gestation was 34±3 weeks and 42.5% were inborn. Significant determinants of neonatal hypothermia at admission included factors like preterm (p=0.03), low birth weight (p=0.005), normal delivery (p=0.012), birth asphyxia (p=0.001) below average socioeconomic status (p=0.001) and long distance (>10 km) travelled by the neonate (p=0.03). Independent variables are resuscitation at birth [p=.001, Odds Ratio (OR), 2.43; Confidence Interval (CI), 1.47 to 4.00], (p=0.001), age less than 24 hours (p=.02; OR 2.25; CI, 1.13 to 4.47), low birth weight (p=0.03; OR,2.0; CI, 1.06 to 3.82), caesarean section(C/S) delivery (p=.006; OR 1.35; CI, 1.18-2.12) and below average economic status (p=0.001; OR, 2.76; CI, 1.56 to 5.90). Conclusion: Incidence of admission hypothermia among neonates in our NICU was 34%. Independent risk factors are resuscitation at birth, very low birth weight, C/S delivery, age less than 24 hours and poor socio-economic condition. Proper thermal care should be provided for neonates both at home and hospitals. DOI: http://dx.doi.org/10.3126/jnps.v33i3.8312   J. Nepal Paediatr. Soc. 2013;33(3):166-171

scholarly journals Prevalence and risk factors of dysnatremia in sick newborns admitted in neonatal intensive care unit: a cross-sectional study

2020 ◽  
Vol 7 (12) ◽  
pp. 2369
Author(s):  
Farogh Hassan ◽  
Vasanth N. Kumar ◽  
Imran Asghar ◽  
Lata Jha ◽  
Indranil Choudhury
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Serum Sodium ◽  
Neonatal Intensive Care ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

Background: The objective of the study was to study the prevalence and various risk factors of dysnatremia in sick newborns admitted in neonatal intensive care unit (NICU).Methods: Cross sectional study conducted in Paediatric Department of tertiary care hospital from February 2016 to October 2016 which includes 384 neonates admitted to NICU during the study period. After informed consent, detailed history was taken and clinical examination carried out in both cases and controls. Blood investigations were done to diagnose sodium levels in sick neonates. Based on the corrected sodium values, the subjects were classified as having hyponatremia (serum sodium <135 meq/l), hypernatremia (serum sodium >145 meq/l) or normonatremia (serum sodium 135 to 145 meq/l).Results: The mean (SD) (range) serum sodium in sick newborns measured was 136.72 (6.7) (115-165) meq/l at a median (range) age of 56.97 (1-545) hours. Out of 384 sodium values obtained, 285 (74.2%) were sent on ≤3 days, 64 (16.7%) between 4th to the 6th day and 35 (9.1%) were sent on ≥7 days. The overall frequency of dysnatremia in 384 sodium values from 384 patients was 142 (37%). Hyponatremia was observed in 117 (30.5%) and hypernatremia in 25 (6.5%) of sodium values. Hyponatremia observed in term, low birth weight, very low birth weight and extremely low birth weight neonates were 16.4%, 25.2%, 67.2% and 100% respectively whereas hypernatremia were 10.1%, 4.6%, 3.4% and 0% respectively. Various risk factors for hyponatremia namely; prematurity, necrotizing enterocolitis, renal failure, birth asphyxia, sepsis, meningitis, vomiting/ nasogastric drainage.Conclusions: Hyponatremia are common in sick newborns in NICU.

scholarly journals Prevalence, aetiology, and impact of paediatric feeding disorders in preterm infants admitted to a neonatal intensive care unit in Cyprus

2021 ◽  
Vol 24 (1) ◽  
pp. 45-53
Author(s):  
Panayiota Senekki-Florent ◽  
Margaret Walshe
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Preterm Infants ◽  
Neonatal Intensive Care ◽  
Phase 1 ◽  
Feeding Disorders ◽  
Phase 2

BACKGROUND: Advancements in neonatal care have resulted in increased survival for preterm infants, with associated risk for paediatric feeding disorders (PFDs), the prevalence of which is relatively unexplored. Risk factors for developing PFDs in this population must be identified. OBJECTIVE: The aim of this study was to determine the epidemiology and risk factors for PFDs in preterm infants with Extremely Low Birth Weight (ELBW); Very Low Birth Weight (VLBW) and Low Birth weight (LBW) in the only neonatal intensive care unit (NICU) in Cyprus. METHODS: This study comprised 2 phases: Phase 1, a retrospective 2-year file audit, informing methodology for Phase 2, a prospective epidemiological study. Profiles of 1027 preterm infants were obtained in Phase 1. In Phase 2, clinical assessment data on 458 preterm infants (N = 224) were analyzed. RESULTS: The prevalence of PFDs was 36.5%. All preterm infants with ELBW and 69%with VLBW exhibited PFDs. Risk factors were birth weight (BW), gestational age (GA), bronchopulmonary dysplasia (BPD), neurological disorders, structural anomalies, and congenital heart disease (CHD). CONCLUSIONS: This unique epidemiological data for one country will inform NICU service provision and direct international research on PFDs in neonates.

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