scholarly journals Prescription Patterns of Antituberculosis Drugs in Treatment of Tuberculosis at a Tertiary Care Hospital in Andgra Pradesh, a Cross-Sectional Study

2020 ◽  
Vol 5 (2) ◽  
Author(s):  
Krishnakanth K ◽  
Chakrapani Cheekavolu ◽  
Poojala Kumar ◽  
Ravi Shankar K ◽  
Jagadeesh A

The success of tuberculosis treatment is based upon the prescription pattern following Revised National Tuberculosis Control Program/National Tuberculosis Elimination Program/World Health Organization guidelines, reflecting the burden of the disease which is increasing yearly. This implicates the variations in prescriptions advised in the treatment of tuberculosis. The present study was aimed to evaluate the prescription patterns of tuberculosis treatment in a tertiary hospital at Andhra Pradesh, India. Ninety-two patients were included in the study after obtaining ethical approval and informed consent. The prescription patterns were evaluated and compared to the standard guidelines. The mean age of the patients was 38.72 and showed male preponderance. Six regimens were used during the treatment. The patients showed good recovery which concludes that following the standard prescription pattern provides a good success rate in the treatment of tuberculosis.

2021 ◽  
pp. 191-194
Author(s):  
Kishore M S ◽  
Narendra Kumar ◽  
S Sindhu

Background: The expanding and challenging eld of psychopharmacology is constantly seeking new and improved drugs to treat psychiatric disorders. Psychotropic drugs utilization in actual clinical practice, effectiveness and safety in the real-life situation needs continuous study. Therefore, the study was undertaken to analyze the prescription pattern of psychotropic drugs. Methods: A Cross sectional study was conducted in the psychiatry out-patient department of a tertiary care hospital for 4 months. Diagnosis was made according to ICD-10 criteria. Prescription pattern was analyzed using World Health Organization (WHO) drug indicators. Results: Psychotropic drugs constituted 74.85% of the prescribed medication. Average number of the psychotropic drugs per prescription was 2.53. Percentage of prescriptions with injectable drugs accounted for 5.13%. 59.28% of the drugs were prescribed by generic names, while the rest were branded. 28% of prescriptions contained psychotropic FDCs (Fixed dose th combination). 78.65% of the drugs were from the WHO's 18 List of Essential Medicines. Among the total psychotropic drugs prescribed, antipsychotics (43.87%) were the most commonly prescribed class of drugs followed by antidepressants (23.32%), anxiolytics (22.13%) and the mood stabilizers (9.88%) were the least. Conclusions: Prescription pattern of the psychotropic drugs were in accordance to the recommendations of various treatment guidelines. Antipsychotics were the most commonly prescribed psychotropic drugs.


Author(s):  
Abhishek Sharma ◽  
Aditya Mathur ◽  
Cecilia Stålsby Lundborg ◽  
Ashish Pathak

Diarrhoea contributes significantly in the under-five childhood morality and mortality worldwide. This cross-sectional study was carried out in a tertiary care hospital in Ujjain, India from July 2015 to June 2016. Consecutive children aged 1 month to 12 years having “some dehydration” and “dehydration” according to World Health Organization classification were eligible to be included in the study. Other signs and symptoms used to assess severe dehydration were capillary refill time, urine output, and abnormal respiratory pattern. A questionnaire was administered to identify risk factors for severe dehydration, which was the primary outcome. Multivariate logistic regression modeling was used to detect independent risk factors for severe dehydration. The study included 332 children, with mean ± standard deviation age of 25.62 ± 31.85 months; out of which, 70%(95% confidence interval [CI] 65 to 75) were diagnosed to have severe dehydration. The independent risk factors for severe dehydration were: child not exclusive breast fed in the first six months of life (AOR 5.67, 95%CI 2.51 to 12.78; p<0.001), history of not receiving oral rehydration solution before hospitalization (AOR 1.34, 95%CI 1.01 to 1.78; p=0.038), history of not receiving oral zinc before hospitalization (AOR 2.66, 95%CI 1.68 to 4.21; p<0.001) and living in overcrowded conditions (AOR 5.52, 95%CI 2.19 to 13.93; p<0.001). The study identified many risk factors associated with severe childhood dehydration; many of them are modifiable though known and effective public health interventions.


2017 ◽  
Vol 56 (207) ◽  
pp. 325-330
Author(s):  
Santosh Pathak ◽  
Nagendra Chaudhary ◽  
Prativa Dhakal ◽  
Shyam Kumar Mahato ◽  
Sandeep Shrestha ◽  
...  

Introduction: Measurement of birth weight (BW), crown heel length (CHL), head circumference (HC) and chest circumference used to assess the intrauterine growth of a baby vary with altitude, race, gender, socio economic status, maternal size, and maternal diseases. The study aimed to construct centile charts for BW, CHL and HC for new born at different gestational ages in western Nepal. Methods:  This was a descriptive cross sectional study done over a period of 15 months in a tertiary care hospital of western Nepal. BW, length, HC and CC were measured within 12-24 hours of birth. Gestational age was estimated from first day of last menstrual period, maternal ultrasonology and New Ballard’s scoring system. Microsoft 2007 Excel and SPSS-16 was used for data analysis. Cole’s Lambda Mu Sigma method was used for constructing centile curves. Results: Out of 2000 babies analysed, 1910 samples were used to construct smoothed intrauterine growth curve of BW, CHL, and HC from 33-42 weeks of gestation. 57.35% (1147) were male, mean gestational age was 38.13 ±2.44 weeks, where 21.5% were preterm and 1.7% post term. The means of BW, CHL, HC and CC were 2744.78 gm, 47.80 cm, 33.18 cm, and 30.20 cm with standard deviations of 528.29, 3.124, 1.78, and 2.35 respectively. These data vary as compared to the Kathmandu data, in case of birth weight for 10th and 90th centiles, and at 90th centile in case of length. Conclusions: This necessitates the update in the existing growth charts and develop in different geographical regions of a country.


2021 ◽  
pp. 28-29
Author(s):  
Jayesh Dhananjay Gosavi ◽  
Deppa H Velankar ◽  
Sumedha M Joshi ◽  
Sumit G Wasnik ◽  
Sudarshan Ramaswamy

Background:It is estimated that annually more than 89 lakh children in the country do not receive all vaccines that are available under the UIP– the highest number compared with any other country in the world. Objective: This study was carried out to assess vaccination coverage of children of age group 12 - 23 month residing in the eld practice area of tertiary hospital. Material & methods: This was sectional study conducted at eld practice area of tertiary care hospital during January 2017 to July 2018. Study population was children in the age group 12-23 month. As per WHO norm for identication of sample size for vaccination coverage in study area 30 cluster sampling method is preferred. Results: In the study 188 (89.52%) children were Fully Immunized. 22 (10.48%) children were partially immunized and none of the child was non immunized. overall coverage of BCG was 98.5, for PENTA3 was 96.3%, OPV3 was 96.3% and Measles was 89.8%. Conclusion: Overall immunization coverage in the area is good and higher than the national coverage level. There is no signicant difference in the immunization status of Male and Female children.


2014 ◽  
Vol 2 (2) ◽  
pp. 64-67 ◽  
Author(s):  
Tanzima Begum ◽  
Md Ismail Khan ◽  
Shamima Kawser ◽  
Md Ehsanul Huq ◽  
Nadira Majid ◽  
...  

Background: Drug can cure ailment when used rationally on the other hand they may become harmful or even may threaten a life when used irrationally. Absence of guidelines for antibiotic use, protocols for rational therapeutics and infection control committees, have led to overuse and misuse of antimicrobials even in different specialized units in hospitals. Objective: The study has been designed to get a picture of use of antibiotics in a tertiary care hospital of Bangladesh. Materials and method: Cross sectional study was conducted in the department of Medicine of Sir Salimullah Medical College and Mitford Hospital, Dhaka, Bangladesh, for 3 months from 1st January 2009 to 31st March 2009. Admitted patients of Medicine unit-1 who got antibiotics were included in the study. Total number of patients was 1563. Results: Five hundred out of 1563 patients were prescribed antibiotics (38%). Out of 500 prescriptions, 68(14%) prescriptions were found irrational. Conclusion: Continuous surveillance should be carried out to reduce the irrational use of antibiotics. DOI: http://dx.doi.org/10.3329/dmcj.v2i2.20526 Delta Med Col J. Jul 2014; 2(2): 64-67


Author(s):  
Rakesh Kumar ◽  
Haresh Kumar ◽  
Sarika Bai ◽  
Azra Shaheen ◽  
Safdar Ali Pervez ◽  
...  

Introdution: Cancer and depression, independently, cause massive human suffering worldwide. By the end of 2030 the unipolar major depression disorder could be as the chief source of ailment as estimated by World Health Organization. Objective: Objective of this study is to detect prevalence the frequency and severity of the depression in cancer patients presenting to tertiary care hospital of Karachi. Methodology: The current prospective cross-sectional research was performed over a period of six months from August 2020 to January 2021 on 179 patients in the Department of Oncology of Civil Hospital Karachi, after approval of synopsis from CPSP and the ethical committee of Civil Hospital. All patients who fulfilled the inclusion criteria and visited OPD of Civil hospital were selected in the study. Informed consent was taken after explaining the procedure, risks and benefits of the study.Patients were assessed clinically by using ICD-10 criteria and then for validity and reliability, patients were screened for presence of depression and its severity through PHQ-9.Patients scoring higher than 4 was labeled as having depression and PHQ-9 score of 5 to 9, 10 to 14, 15 to 19, 20-27 were labeled mild, moderate, moderately severe and severe depression correspondingly. Observed data was entered in the predesigned Performa was gathered and SPSS version 20.0 was used for data analysis. Mean ± SD of age was 47.75±14.901years. Out of 179 patients 95 (53.1%) were male and 84 (46.9%) were female. 93(52%) cancer patients were depressed while 86(48%) were normal. Patients suffering from mild depression were 3.2%, moderate depression were 54.85%, moderately severe depressed were 19.4%, while 22.6% cancer patients were severely depressed. It is to be concluded that out of 179cancer patients 93(52%) diagnosed to have depression while 86(48%) did not have depression. Based on our study findings, it is suggested that depression commonly presented in cancer patients and there is a need to screen all cancer patients for depressive disorder.


Author(s):  
Rucha M. Shinde ◽  
Anand S. Kale ◽  
Mahadeo P. Sawant

Background: Drug utilization study is an important tool to study the clinical use of drugs and its impact on healthcare system. DUS in patients with HTN and DM is essential to observe the changing prescribing attitude of physicians with the aim to promote rational use of drugs and to minimize the adverse drug reactions.Methods: A cross sectional observational study was conducted on randomly selected patients attending medicine outpatient department in a tertiary care hospital. Drug prescription sheets of 600 patients were studied for 18 months from January 2016 to June 2017 and the prescribing pattern was analysed using the World Health Organization basic drug indicators.Results: Total 2029 drugs were prescribed to 600 patients that belonged to various classes. The average number of drugs prescribed per encounter was 3.4. Majority (61.5%) drugs were prescribed using generic names. Percentage encounters with the antibiotics and injections were 6.3 and 11.5 per cent respectively. 38% drugs were prescribed from the 20th edition of WHO Model List of Essential Medicines. PDD in the current study was found to be significantly less than WHO DDD in all drugs. All of the prescriptions in the present study conformed to WHO guidelines and majority of them with JNC VIII guidelines.Conclusions: The findings of this study are comparable to those of other studies. However, there is a scope of improvement in areas such as overdosing, prescribing more by generic names instead of brand names and from WHO Model List of Essential Medicines.


2014 ◽  
Vol 3 (8) ◽  
pp. 309-312 ◽  
Author(s):  
Muhammad Zahid Iqbal ◽  
Muhammad Shahid Iqbal ◽  
Dayana Nicholas ◽  
Jamaluddin Awang ◽  
Amer Hayat Khan ◽  
...  

To assess the adherence of physicians involved in the management of diabetes mellitus with or without co-morbidities with reference to Clinical Practice Guideline 2009 given by Ministry of Health Malaysia in the tertiary care hospital, Pinang General Hospital Malaysia. Cross-sectional study was done at tertiary care hospital, Penang, Malaysia. The total 51 physicians and 1020 patient’s prescriptions written by same physicians were taken from the record of the Penang General Hospital (20 prescriptions for each enrolled physician). All 1020 patients were suffering from diabetes mellitus with or without co-morbidities. These patients were recruited from the different wards of the Penang General Hospital. Depending on the recommendations of CPG 2009 the prescriptions of patients were divided into adherent and non-adherent prescriptions. The overall good level of physician adherence was seen with respect to the recommendations of CPG 2009 in all prescriptions. A statistically significant negative association (?= 0.094, p-value=0.003) was observed between diabetes mellitus control and co-morbidities. CPG adherent had statistically weak negative association (?= -0.081, p-value=0.010) with patients having co-morbidities. No statistically significant association was observed between CPG adherence and any other co-morbidity. The study explored the several features of prescription pattern of physicians involved in the management of diabetes mellitus with or without co-morbidities and recognized the need for improvement in their prescription pattern for treating the diabetes mellitus.DOI: http://dx.doi.org/10.3329/icpj.v3i8.19405 International Current Pharmaceutical Journal, July 2014, 3(8): 309-312


2020 ◽  
Vol 27 (12) ◽  
pp. 2618-2621
Author(s):  
Nadia Taj ◽  
Saba Javed ◽  
Munazza Munir ◽  
Anam Naz ◽  
Asma Sajid ◽  
...  

Objectives: To find the frequency of iron deficient anemia and thalassemia in anemic patient reporting in tertiary hospital in Multan. Study Design: Cross Sectional study. Setting: Department of Obstetrics and Gynecology in Nishtar Hospital, Multan. Period: 20th October 2018 to 20th April 2019. Material & Method: In this study total 260 females with anemia HB<10.5g/dl were incorporated. Blood of all the patients were collected following the septic measures in CBC vial for counting of hemoglobin and blood investigation serum ferritin [<11ng/ml] and HB electrophoresis HBA [>6]. Gestational age was predicted depending upon last period of menstruation. Results: Age of patients in this study was between 24 to 34 year with the average age of 29.9±2.3 year, average gestational age 33.2±2.11 week, average parity 1.46±1.3. Iron deficient anemia was observed in 88.4 percent patient. Thalassemia was observed in 5.7 percent patient. Conclusion: The results of our study revealed that iron deficiency and thalassemia are significant contributing factors of anemia in patients reporting tertiary care hospitals Multan. General screening for carriers of thalassemia should be provided to all pregnant females attending prenatal care.


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