scholarly journals Room Sharing in Hospitalized Children With Bronchiolitis and the Occurrence of Hospital-Acquired Infections: A Prospective Cohort Study

2019 ◽  
Vol 9 (6) ◽  
pp. 415-422 ◽  
Author(s):  
Jolita Bekhof ◽  
Mirjam Wessels ◽  
Eline ten Velde ◽  
Minke Hoekstra ◽  
Veerle Langenhorst ◽  
...  
PLoS ONE ◽  
2015 ◽  
Vol 10 (4) ◽  
pp. e0122136 ◽  
Author(s):  
Jordan A. Kempker ◽  
Kathryn G. West ◽  
Russell R. Kempker ◽  
Oranan Siwamogsatham ◽  
Jessica A. Alvarez ◽  
...  

The Lancet ◽  
2011 ◽  
Vol 378 (9808) ◽  
pp. 2021-2027 ◽  
Author(s):  
Alexander M Aiken ◽  
Neema Mturi ◽  
Patricia Njuguna ◽  
Shebe Mohammed ◽  
James A Berkley ◽  
...  

2018 ◽  
Vol 5 (suppl_1) ◽  
pp. S345-S346
Author(s):  
Min Hyung Kim ◽  
Su Jin Jeong ◽  
Seong Gyu Lee ◽  
Ki Sook Kim ◽  
Yoon Ji Heo ◽  
...  

Abstract Background Hand hygiene and isolation precaution are often difficult to sustain, requiring additional measure to control multidrug-resistant organisms (MDRO) transmission. It was suggested that continuously antimicrobial surfaces could offer superior control of surface bioburden.Thus, we sought to decide the efficacy of photocatalyst antimicrobial coating in reducing MDRO acquisition in high incidence setting. Methods At an institute where used to have high incidence rate of methicillin-resistant Staphylococcus aureus (MRSA), we performed prospective cohort study involving patients hospitalized in medical intensive care unit. Five months of preintervention (where routine infection control measures were maintained) data were compared with 5 months of postintervention (after titanium dioxide-based photocatalyst were coated on high touch surfaces) data. The acquisition rate of MDROs and the rates of hospital acquired blood stream infection (BSI), pneumonia, urinary tract infection (UTI), and Clostridium difficile-associated disease (CDAD) were compared using Cox proportional hazards regression analysis. Results A total of 621 patients were included. There was significant decrease in MRSA acquisition rate after photocatalyst antimicrobial coating. (hazard ratio, 0.37; 95% CI, 0.14–0.99; P = 0.04.) However, acquisition rates of vancomycin-resistant Enterococcus spp. and multidrug-resistant Acinetobacter baunmannii had not significantly decreased. The hazard of acquiring hospital acquired pneumonia during intervention period compared with baseline period was 0.46 (95% CI, 0.23–0.94; P = 0.03). There were not significant reduction in hospital acquired BSI, UTI, and CDAD, after photocatalyst antimicrobial coating. Conclusion MRSA acquisition rate and hospital acquired pneumonia were significantly reduced after photocatalyst antimicrobial coating. This study provides evidence that photocatalyst antimicrobial disinfection can be an adjunctive measure to control MRSA acquisition in high incidence setting. Disclosures All authors: No reported disclosures.


2016 ◽  
Vol 67 (13) ◽  
pp. 976 ◽  
Author(s):  
Therese M. Giglia ◽  
Whitney L. Petrosa ◽  
Kelly Veneziale ◽  
Karen Murphy ◽  
Janine Pappas ◽  
...  

2016 ◽  
Vol 22 (5) ◽  
pp. 461.e7-461.e9 ◽  
Author(s):  
E. Munier-Marion ◽  
T. Bénet ◽  
C. Régis ◽  
B. Lina ◽  
F. Morfin ◽  
...  

Author(s):  
Colette Sih ◽  
Bertrand Hugo Mbatchou-Ngahane ◽  
Yannick Mboue-Djieka ◽  
Marie C Ngueng-Eke ◽  
Nicole T Mbarga ◽  
...  

Abstract Background Hospital-acquired complications (HACs) contribute to increased morbidity, mortality and hospital costs. However, their burden is often overlooked in resource-limited settings. We sought to determine the incidence, risk factors and effects of HACs on direct medical costs. Methods This was a prospective cohort study conducted in the Internal Medicine inpatient ward of Douala General Hospital over 3 mo. Patients were examined daily from admission to discharge, transfer or death. Incidence of HACs was calculated and risk factors of HACs were determined using univariate and multivariate regression models. Results The cumulative incidence rate of HACs in 230 participants was 29.2/1000 patient-days. The incidence rate of infectious and non-infectious complications was 8.4/1000 and 20.9/1000 patient-days, respectively. The most common HAC was constipation (8.3/1000 patient-days). The most common infection was urinary tract infection (3.7/1000 patient-days). HIV infection and length of stay >8 d were significantly associated with the occurrence of HACs. Deep vein thrombosis was associated with the highest direct medical cost. Conclusion The incidence of HACs is high in our setting and leads to increased length of hospital stays as well as greater direct medical costs. Thus, there is a need for effective preventive strategies.


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