Fifty Years of Medical Genetics

PEDIATRICS ◽  
1959 ◽  
Vol 23 (3) ◽  
pp. 581-581
Keyword(s):  
Medical Literature ◽  
Medical Science ◽  
Medical Genetics ◽  
Future Developments ◽  
General Terms ◽  
Hereditary Factors ◽  
Metabolic Reactions ◽  
Genetically Determined ◽  
Made In

Many articles are appearing in the medical literature which aim to provide a discussion of the application of genetics to medical science in general terms for the benefit of the clinician without training in genetics. The present lecture is an especially lucid and stimulating account of the elements of genetics and the progress that is being made in the elucidation of diseases by the application of genetics. The manner in which metabolic reactions may be affected, directly or indirectly, by genetically determined enzymic defects is briefly and clearly presented. The interplay between environmental and hereditary factors is considered. Sufficient background is provided to enable one to observe future developments in the application of genetics to medicine with a better understanding and consequently keener interest.

scholarly journals Comparative Dermatoglyphic Study Between Schizophrenic Patients and Healthy Controls

KYAMC Journal ◽  
2019 ◽  
Vol 10 (2) ◽  
pp. 66-72
Author(s):  
Rashed Mustafa ◽  
Akhtari Afroze ◽  
Sabrina Sobnom ◽  
Abdullah Al Mamun Hossain ◽  
Md Shameem Ahmed ◽  
...  
Keyword(s):  
Medical Science ◽  
Control Loop ◽  
Ridge Pattern ◽  
Fingerprint Pattern ◽  
Loop Pattern ◽  
Schizophrenic Patients ◽  
Healthy Control ◽  
Being There ◽  
Genetically Determined ◽  
Selection Of

Introduction: Dermatoglyphics is the branch of medical science that is concerned with the study of dermal ridges present on fingers, palms, toes and the soles of the human being. There may have some association between fingerprints and schizophrenia regarding the developmental background of skin ridge pattern and brain.So this study was conducted to find out the fingerprint patterns in schizophrenic patients and also to find out sex variation of fingerprint patterns in between schizophrenic male and schizophrenic female. Objective: This study was carried out with a view to find out the fingerprint patterns in schizophrenic patients. Methodology: A total of 200 samples were selected. Among them, 100 were schizophrenic and 100 were normal healthy control. Samples were taken in between 15 to 40 years of age. Selection of schizophrenic sample was performed by a qualified psychiatrist. Fingerprints were taken by Ink and pad method, described by Cummins. Fingerprint patterns were observed by using a magnifying glass. Results: The frequency of common fingerprint pattern was reduced in schizophrenia. In healthy control loop pattern was predominant. But in schizophrenia frequency of loop pattern was reduced and there was an increased frequency of whorl and arch pattern. Conclusion: Asdermatoglyphics is genetically determined, predominant whorl and arch pattern found among the schizophrenic patients might provide a presumptive value which would aid in diagnosis of the disease. KYAMC Journal Vol. 10, No.-2, July 2019, Page 66-72

scholarly journals The Normative Influence of the UN Guiding Principles on the Kampala Convention in the Protection of Internally Displaced Persons in Africa

2021 ◽  
pp. 1-14
Author(s):  
Francis M Deng ◽  
Romola Adeola
Keyword(s):  
Internal Displacement ◽  
Internally Displaced Persons ◽  
African Union ◽  
Displaced Persons ◽  
Political Commitment ◽  
Internally Displaced ◽  
General Terms ◽  
African Context ◽  
Guiding Principles ◽  
Made In

Abstract Over the last several decades, states have demonstrated significant political commitment towards advancing protection and assistance for internally displaced persons. A notable form in which this commitment has been reflected is in the emergence of normative standards, with the UN Guiding Principles on Internal Displacement (UNGP) as the guiding text. The fact that the UNGP framework has found expression in the landscape on internal displacement is evidenced at various levels of governance. Within the African context, the African Union Convention for the Protection and Assistance of Internally Displaced Persons in Africa (Kampala Convention) draws on pertinent normative frameworks, with the UNGP as the leading framework. While this point is often made in general terms, this article focuses on the extent to which the norm on internal displacement has diffused and expanded within the African context.

Mutagenesis via Insertional or Restriction Enzyme-Mediated Integration (REMI) as a Tool to Tag Pathogenicity Related Genes in Plant Pathogenic Fungi

1999 ◽  
Vol 380 (7-8) ◽  
pp. 855-864 ◽  
Author(s):  
F. J. Maier ◽  
W. Schäfer
Keyword(s):  
Restriction Enzyme ◽  
Molecular Basis ◽  
Insertional Mutagenesis ◽  
Transformation Efficiency ◽  
Pathogenic Fungi ◽  
Transformation Protocol ◽  
Vector Integration ◽  
Future Developments ◽  
Genetically Determined ◽  
Remi Mutagenesis

Abstract Random insertional mutagenesis is a powerful tool to investigate the molecular basis of most genetically determined processes, for example in pathogenic fungi. An improved version of this method is the insertional mutagenesis via restriction enzyme mediated integration (REMI). Transformation efficiency and mode of vector integration are species dependent and further influenced by vector conformation, restriction enzyme activity, and transformation protocol. An overview is given, covering the mutants and already identified genes obtained after REMI mutagenesis. An outlook describes the future developments in the field.

Le Problème de L'HéréDité Dans les Syndromes Epileptiques, by Renaud Delaveleye. Paris: Expansion Scientifique Français (15, rue Saint-Benoit), 1969, 235 pp., $7.50

PEDIATRICS ◽  
1970 ◽  
Vol 46 (1) ◽  
pp. 169-169
Author(s):  
Cesare T. Lombroso
Keyword(s):  
Reference Material ◽  
Genetic Aspect ◽  
Hereditary Factors ◽  
The Subject ◽  
Genetically Determined ◽  
Vexing Problem

This monograph deals with the eugenically vexing problem of the hereditary factors in epilepsy. Its first section covers quite adequately the literature on the subject, and presents some of the conflicting opinions. In a second section the author presents his own data. His conclusions are that the epilepsies do not show a unitary genetic aspect, but rather they are the resuits of a constellation of factors of which some are genetically determined. A useful monograph results both because of its abundant reference material, and new observations reproted.

A Review of the Effect of Lower-Extremity Pathology on Automobile Driving Function

2019 ◽  
Vol 109 (2) ◽  
pp. 132-140 ◽  
Author(s):  
Andrew J. Meyr ◽  
Laura E. Sansosti
Keyword(s):  
Lower Extremity ◽  
Medical Literature ◽  
Surgical Intervention ◽  
Automobile Driving ◽  
Foot And Ankle ◽  
State Regulations ◽  
Driving Function ◽  
Lower Limb Surgery ◽  
Musculoskeletal Pathology ◽  
Made In

The effect of lower-extremity pathology and surgical intervention on automobile driving function has been a topic of contemporary interest in the medical literature. The objective of this review was to summarize the topic of driving function in the setting of lower-extremity impairment. Included studies involved lower-extremity immobilization devices, elective and traumatic lower-limb surgery, chronic musculoskeletal pathology, and diabetes as it relates to the foot and ankle, focusing on the effect each may have on driving function. We also discuss the basic US state regulations with respect to impaired driving and changes to automobile structure that can be made in the setting of lower-extremity pathology.

scholarly journals Some Observations on the Interdigitation of Advances in Medical Science and Mathematics

2013 ◽  
Vol 79 (12) ◽  
pp. 1231-1234 ◽  
Author(s):  
Michael James Glamore ◽  
James L. West ◽  
James Patrick O'leary
Keyword(s):  
Medical Science ◽  
Written Word ◽  
And Mathematics ◽  
Made In

The immense advancement of our understanding of disease processes has not been a uniform progression related to the passage of time. Advances have been made in “lurches” and “catches” since the advent of the written word. There has been a remarkable interdependency between such advances in medicine and advances in mathematics that has proved beneficial to both. This work explores some of these critical relationships and documents how the individuals involved contributed to advances in each.

scholarly journals The oblique reflexion of very long wireless waves from the ionosphere

1947 ◽  
Vol 189 (1016) ◽  
pp. 130-147 ◽  
Keyword(s):  
Magnetic Field ◽  
Experimental Data ◽  
Theoretical Basis ◽  
Plane Waves ◽  
Angle Of Incidence ◽  
Vertical Magnetic Field ◽  
Radio Waves ◽  
Contour Integrals ◽  
General Terms ◽  
Made In

An attempt is made in the paper to provide a satisfactory theoretical basis for a future discussion of the experimental data on the propagation of very long radio waves (18,800 m.) given by Best, Ratcliffe & Wilkes, and Budden, Ratcliffe & Wilkes. The reflexion of very long plane waves incident obliquely on a horizontally stratified ionized medium with a vertical magnetic field is first considered in general terms, and it is shown that the medium can be divided into a transition region and a reflecting region. If the ionization in the reflecting region increases linearly with height it is shown that propagation is governed by the following equations: ∂ 2 L / ∂ζ 2 + (α + ζ) L + β M = 0, ∂ 2 M / ∂ζ 2 + (α - ζ) M + β L = 0, where α and β are constants depending on the angle of incidence. Under the conditions of the experiments β is small, and a solution, in terms of contour integrals, valid in this case is obtained.

Patients' views on decision making in advanced cancer

2009 ◽  
Vol 7 (2) ◽  
pp. 181-185 ◽  
Author(s):  
Jennifer Philip ◽  
Michelle Gold ◽  
Max Schwarz ◽  
Paul Komesaroff
Keyword(s):  
Decision Making ◽  
Cancer Treatment ◽  
Advanced Cancer ◽  
Medical Literature ◽  
Medical Condition ◽  
Treatment Center ◽  
Advanced Malignancy ◽  
Decision Making Processes ◽  
Made In

ABSTRACTObjective:To explore patients' understanding of decision making in the treatment of advanced cancer and to determine the factors they believe important to these processes in their care.Methods:Surveys were distributed to consecutive outpatients with advanced malignancy attending a comprehensive cancer treatment center.Results:Patients believed that the medical condition (94%), their doctors' experience (81%), and the medical literature (73%) are the most important factors for decisions made in their care. They also value their relationship with the doctor (63%) and their own (the patients') values (63%), and just over a third considered their family's values and the doctors' personality important. Most did not believe the doctors' values should influence decisions made. They were mindful of the uncertainty involved in decisions in the setting of advanced cancer.Significance of results:Overall, patients were satisfied with the decision-making processes and they understood and highly regarded the incorporation of factors, other than their medical condition, in their care.

New Testament Eschatology

1953 ◽  
Vol 6 (3) ◽  
pp. 225-243
Author(s):  
C. K. Barrett
Keyword(s):  
New Testament ◽  
The Past ◽  
General Terms ◽  
Massacre Of The Innocents ◽  
Made In

The ministry of Jesus is represented by the evangelists as itself an eschatological event. This presentation involved them (writing as they did from thirty to seventy years after the event) in paradox, but the paradox is of the essence of their faith.It is a primary feature of the gospels that the story of Jesus is set forth as the fulfilment of OT prophecy. This is sometimes done in the crudest and most artificial manner, as for example when Jeremiah's picture of Rachel weeping for her children (Jer. 31.14 (38.15)) is applied to the massacre of the innocents (Matt. 2.17 f). Sometimes again the appeal to the OT is made in general terms without citation of a particular passage (e.g. Mark 14.21 ). The passion narratives in particular are marked by OT references and allusions, but the whole ministry is introduced by Mark (1.15) with the proclamation, πεπλ⋯ρωται ⋯ καιρóς, and the καιρóς in question is evidently the time foretold (or currently believed to have been foretold) by the prophets. That which in the past they had longed to see and hear, and had not seen and heard, was now before men, visible and audible: blessed indeed were those who could see and hear (Matt. 13.16 f; Luke 10.23 f).

scholarly journals Constitutional approach in studying human diseases at the present stage

2018 ◽  
pp. 70-77
Author(s):  
N. Yu. Klimov ◽  
Y. Yu. Vinnik ◽  
A. V. Andreychikov ◽  
A. S. Maximov
Keyword(s):  
Medical Science ◽  
The Body ◽  
Age Changes ◽  
Present Stage ◽  
Valuable Contribution ◽  
Physical Activity Change ◽  
Genetically Determined ◽  
The Relationship ◽  
Benign Hyperplasia

The study of the relationship between somatotypological features of a person and the course of diseases is today an important stage in the development of medical science. The somatotype is genetically determined and is a constant objective characteristic of a person from birth to death. Age changes, illnesses, increased physical activity change the size and shape of the body, but not the somatotype. To date, considerable theoretical and clinical material has been accumulated, which confirms the important role of the somatotype in the emergence and development of pathological processes in the human body. In the literature there are data on somatotypological features of the course of diseases of the respiratory system, cardiovascular and nervous systems, and the gastrointestinal tract. At the same time, when analyzing the literature data, we did not find any work on the effect of the somatotype on the course of benign hyperplasia andprostate cancer. The identification of these patterns will be a valuable contribution to the early diagnosis of the above listed diseases.

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