AUDIOLOGICAL FINDINGS IN HEARING LOSS SECONDARY TO MATERNAL RUBELLA

PEDIATRICS ◽  
1970 ◽  
Vol 45 (2) ◽  
pp. 225-229
Author(s):  
Thomas E. Borton ◽  
Earl W. Stark

The purpose of this investigation was to describe the audiological findings in hearing loss secondary to maternal rubella. The mothers of all but three of the 80 subjects contracted rubella during the first trimester of pregnancy. Over 75.0% sustained the infection during the second or third month of gestation. The greatest incidence of additional congenital defects was found in those instances in which maternal rubella occurred during the first month of pregnancy. In almost all instances, all other congenital abnormalities had been identified prior to diagnosis of hearing impairment. Therefore, careful attention should be given to the possibility of undiagnosed hearing impairment being present in children whose mothers contracted rubella during the time of pregnancy. Audiograms were available for 55 of the subjects. The majority of these 55 subjects demonstrated hearing impairments classified as moderately severe to profound in degree. Ear differences were found in only 16 (29.0%) of the 55 children. No audiometric configuration emerged as representative of hearing impairment secondary to maternal rubella. Nevertheless, 40% of the audiograms were falling in pattern. The majority of the subjects demonstrated sensorineural impairments. However, about one-fourth exhibited mixed-type losses, according to the audiogram.

2000 ◽  
Vol 13 (4) ◽  
pp. 571-587 ◽  
Author(s):  
Jia-Yee Lee ◽  
D. Scott Bowden

SUMMARY Rubella virus (RV) is the causative agent of the disease known more popularly as German measles. Rubella is predominantly a childhood disease and is endemic throughout the world. Natural infections of rubella occur only in humans and are generally mild. Complications of rubella infection, most commonly polyarthralgia in adult women, do exist; occasionally more serious sequelae occur. However, the primary public health concern of RV infection is its teratogenicity. RV infection of women during the first trimester of pregnancy can induce a spectrum of congenital defects in the newborn, known as congenital rubella syndrome (CRS). The development of vaccines and implementation of vaccination strategies have substantially reduced the incidence of disease and in turn of CRS in developed countries. The pathway whereby RV infection leads to teratogenesis has not been elucidated, but the cytopathology in infected fetal tissues suggests necrosis and/or apoptosis as well as inhibition of cell division of critical precursor cells involved in organogenesis. In cell culture, a number of unusual features of RV replication have been observed, including mitochondrial abnormalities, and disruption of the cytoskeleton; these manifestations are most probably linked and play some role in RV teratogenesis. Further understanding of the mechanism of RV teratogenesis will be brought about by the investigation of RV replication and virus-host interactions.


The Lancet ◽  
1998 ◽  
Vol 351 (9116) ◽  
pp. 1624-1627 ◽  
Author(s):  
Claudette Hajaj Gonzalez ◽  
Maria Joaquina Marques-Dias ◽  
Chong Ae Kim ◽  
Sofia MM Sugayama ◽  
José Albino Da Paz ◽  
...  

2017 ◽  
Vol 28 (06) ◽  
pp. 491-505 ◽  
Author(s):  
Nehzat Koohi ◽  
Deborah A. Vickers ◽  
Rahul Lakshmanan ◽  
Hoskote Chandrashekar ◽  
David J. Werring ◽  
...  

Background: Stroke survivors may suffer from a range of hearing impairments that may restrict their participation in postacute rehabilitation programs. Hearing impairment may have a significant impact on listening, linguistic skills, and overall communication of the affected stroke patient. However, no studies sought to systematically characterize auditory function of stroke patients in detail, to establish the different types of hearing impairments in this cohort of patients. Such information would be clinically useful in understanding and addressing the hearing needs of stroke survivors. Purpose: The present study aimed to characterize and classify the hearing impairments, using a detailed audiological assessment test battery, in order to determine the level of clinical need and inform appropriate rehabilitation for this patient population. Research Design: A case–control study. Study Sample: Forty-two recruited stroke patients who were discharged from a stroke unit and 40 control participants matched for age. Data Collection and Analysis: All participants underwent pure-tone audiometry and immittance measurements including acoustic reflex threshold, transient-evoked otoacoustic emissions, auditory-evoked brainstem response, and a central auditory processing assessment battery, performed in a single session. Hearing impairments were classified as peripheral hearing loss (cochlear and neural type), central auditory processing disorder (CAPD), and as a combination of CAPD and peripheral hearing loss. Results: Overall mean hearing thresholds were not significantly different between the control and stroke groups. The most common type of hearing impairment in stroke patients was the combination type, “peripheral and CAPD,” in the 61- to 80-yr-old subgroup (in 55%), and auditory processing deficits in 18- to 60-yr-olds (in 40%), which were both significantly higher than in controls. Conclusions: This is the first study to examine hearing function in detail in stroke patients. Given the importance of hearing for the efficiency of communication, it is essential to identify hearing impairments and differentiate peripheral and central deficits to define an appropriate intervention plan.


1986 ◽  
Vol 67 (5) ◽  
pp. 370-372
Author(s):  
A. Ya. Nugumanov

When studying the auditory function of patients suffering from unilateral chronic purulent otitis media for a long time, we noticed that along with hearing reduction in the diseased ear of the mixed type, there was often hearing reduction in the opposite ear of the neurosensory hearing loss type. These changes were even more pronounced when chronic purulent otitis media was combined with labyrinthitis. In patients aged 50 years and older, hearing loss in the opposite ear, exceeding age thresholds, was more frequent.


2021 ◽  
Vol 20 (3) ◽  
pp. 39-50
Author(s):  
A. A. Korneenkov ◽  
◽  
S. V. Ryazantsev ◽  
S. V. Levin ◽  
A. V. Khramov ◽  
...  

The aim of the study is a spatial and statistical analysis of hearing loss of various types (conductive, sensorineural, mixed) and deafness in the adult population of the Chelyabinsk region, assessment of its dynamics and the impact of environmental stress in the place of residence. The study materials were data from the regional audiological center of the Chelyabinsk regional clinical hospital for the period from 2016–2020. Epidemiological issues of the spread of diseases were studied using the methods of spatial analysis, in the R software environment. The main tasks of spatial analysis were to visualize a point pattern from the geographical coordinates of the patient’s places of residence, assess the properties of the spatial process that generates this point pattern, test the hypothesis about the spatial randomness of this process and the influence of the ecological situation on it. It was found that more than half of all primary visits were patients with bilateral sensorineural hearing loss. The number of patients who applied for the year during the observation period fluctuates within the average. Of all hearing impairments, the highest values of relative incidence are characteristic of sensorineural hearing loss, which has a direct relationship with age. The intensity of detection in patients with hearing impairment and deafness is directly related to the size of the living population. The existing division into zones with different ecological situations does not have a statistically significant (p <0.05) effect on the ratio of the number of patients with hearing impairments to the population.


2018 ◽  
Vol 24 (2) ◽  
pp. 168-185 ◽  
Author(s):  
Robert Fulford ◽  
Carl Hopkins ◽  
Gary Seiffert ◽  
Jane Ginsborg

Evidence suggests that musicians may be more susceptible to developing a hearing impairment due to increased exposure to loud sounds over the lifespan. Hearing impairments can affect musical performance behaviours, yet research suggests they do not significantly affect ensemble synchrony unless the hearing loss is severe or profound. This study investigated the effect of reduced auditory feedback on ensemble synchrony, looking behaviour and playing level. Four violinists, with self-reported normal hearing, formed two duos in acoustically-isolated rooms separated by a glass window. Each player received feedback from their own and their co-performer’s playing attenuated by 0, 10, 20, 30 and 40 dB. Video recordings of their looking behaviours were coded and signed asynchronies were identified in the audio files. The strongest effects found were bi-directional changes to playing levels as a result of auditory feedback levels, which increased when a player’s own feedback was reduced and reduced when co-performer feedback was attenuated. Violinists’ looking behaviour was found to increase when co-performer feedback was attenuated by 20 dB or more relative to their own, such that they glanced more frequently and looked for longer towards their partners. There were no effects of auditory attenuation on ensemble synchrony, even with 40 dB attenuation. The results indicate that “self-to-other” sound level ratios are more likely to prompt compensatory musical performance behaviours than an individual’s hearing ability.


1986 ◽  
Vol 51 (1) ◽  
pp. 53-62 ◽  
Author(s):  
Julia M. Davis ◽  
Jill Elfenbein ◽  
Robert Schum ◽  
Ruth A. Bentler

An extensive psychoeducational evaluation was administered to 40 hearing-impaired children to investigate the effects of degree of hearing impairment, age, and other factors on intellectual, social, academic, and language behavior. Although children varied greatly in performance, hearing loss of any degree appeared to affect psychoeducational development adversely, leading to the conclusion that even minimal hearing loss places children at risk for language and learning problems.


1979 ◽  
Vol 44 (2) ◽  
pp. 220-229 ◽  
Author(s):  
Arthur J. Dahle ◽  
Faye P. McCollister ◽  
Sergio Stagno ◽  
David W. Reynolds ◽  
Holly E. Hoffman

Audiological assessment of 86 children with congenital cytomegalovirus infection revealed progressive hearing loss in four of 12 subjects with sensorineural hearing impairments. Case descriptions are presented documenting the progression of the hearing loss. In view of the findings, children with congenital cytomegalovirus should be monitored closely to insure detection of possible delayed or progressive hearing impairment and delivery of appropriate habilitative services.


Open Medicine ◽  
2011 ◽  
Vol 6 (4) ◽  
pp. 435-441
Author(s):  
Jana Mašková ◽  
Antonín Šípek ◽  
Peter Kollár

AbstractThe aim was to identify and quantify the association between the use of particular medications during the first trimester of pregnancy and selected congenital abnormalities (CAs) of newborns. Data were from the Czech National Registry of CAs. We used a case-control design, and collected total of 7285 cases and 9143 controls. Thiethylperazine and iron compounds had no effect on development of CAs. Lower odds ratio and potentially protective associations were found between CAs and bioflavonoids, folic acid, progesterone, levothyroxine, and iodine therapy. Since the protective effect of bioflavonoids was not described before, analysis of interaction with other drugs was performed. However, their protective effect was not confirmed and the strongest significant protective effect was detected in combination of bioflavonoids and progesterone. Increased odds ratio were identified for hydroxyprogesterone, phenoxymethylpenicillin, aspirin, paracetamol and valproic acid. The association between paracetamol and congenital foot deformities was not significant, while the same association for the whole group of CAs and deformities of musculoskeletal system had significantly increased odds ratio. Except newly described effect of bioflavonoids, our results are in agreement with risk categories defined by health authorities in USA and Australia, and with results of other studies. According to our results, paracetamol does not influence development of congenital foot deformities.


2020 ◽  
Vol 3 (9) ◽  
pp. 242-244
Author(s):  
Muzaffarova Nodira Mardonovna

The degree of speech development is not the same as that of hearing impairment and depends on the following factors: the degree of hearing impairment; the time of onset of the hearing analyzer defect; pedagogical conditions of the child after hearing analyzer dysfunction; specific characteristics of the child. Each of the above factors plays a major role in assessing children’s speech. Hearing and speech development in children are directly related. The more a child’s hearing, the more speech is affected. If the importance of hearing is low, then the deviation of speech is not pronounced. If there is a hearing loss, the child will remain deaf until special education begins. With moderate hearing loss, there are disturbances in the phonetic, lexical, grammatical side of speech. Hearing loss can occur at different times in a child’s life. The presence or absence of a secondary appearance of the defect depends on the time factor. The faster the impairment occurs, the more it affects the formation of speech function. In a child under the age of two, the ability to hear leads to a complete lack of speech if speech is not yet formed. By the age of 3-3.5, hearing loss leads to loss of formed speech. If special preparation is not started immediately, speech will be almost completely broken by the age of 4-5 with full hearing. At the age of 6-7 years, hearing loss leads to a sharp deterioration of the child's speech, and without special pedagogical assistance, speech gradually deteriorates.


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