Comparative analysis of the postvaccinal immune response in sheep in two farms after vaccination against infectious agalactia – a field study
The aim of the present study was to detect differences in immune response in sheep from 2 small extensive farms against contagious agalactia, after treatments against helminths and optimization of the diet (farm 2). The one-year experimental period was divided into 2 six-months subperiods. The first without intervention, the second after changes in some of the management conditions. Samples for every subperiods, obtained from the day of vaccination and 3, 7, 14, 30, 60, 90, 120, 180 days thereafter were examined. The samples were assayed by means of indirect ELISA. It was found that the antibody titer increased rapidly after administration of the vaccine, reached a maximum between 7 and 30 days, and decreased rapidly after the 90th day of the experimental period. Significantly higher (P <0.05) antibody titers were found in farm 2 after anti-parasite treatments compared to farm 1.