scholarly journals A kézátültetés története: fejlődés a műtéti technikában, a gyógyszeres kezelésben és az átültetett kezek túlélésében. Irodalmi áttekintés

2017 ◽  
Vol 158 (38) ◽  
pp. 1483-1487
Author(s):  
Vilmos Bíró

Abstract: The author summarizes briefly the history of hand allograft transplantation, the basics of the operative technics, and the medicinal treatment of the immunosuppression. He establishes that this operation requires complicated team-work: many specialists must be united in the interest of the successful final outcome. The biggest problem is not the technical challenge of the complicated operation, but the ineffectiveness of immunosuppression, its complications; even though significant development has happened in this field and experimental results are also encouraging. The author discusses these questions in this publication in the mirror of literature data. He states, that a successful hand transplantation, with its sensory and motoric functions can increase quality of life, in contrast with the ortheses. Orv Hetil. 2017; 158(38): 1483–1487.

2020 ◽  
pp. 105566562098133
Author(s):  
Alyssa Fritz ◽  
Diana S. Jodeh ◽  
Fatima Qamar ◽  
James J. Cray ◽  
S. Alex Rottgers

Introduction: Oronasal fistulae following palatoplasty may affect patients’ quality of life by impacting their ability to eat, speak, and maintain oral hygiene. We aimed to quantify the impact of previous oronasal fistula repair on patients’ quality of life using patient-reported outcome psychometric tools. Methods: A cross-sectional study of 8- to 9-year-old patients with cleft palate and/or lip was completed. Patients who had a cleft team clinic between September 2018 and August 2019 were recruited. Participants were divided into 2 groups (no fistula, prior fistula repair). Differences in the individual CLEFT-Q and Child Oral Health Impact Profile-Short Form 19 (COHIP-SF 19) Oral Health scores between the 2 groups were evaluated using a multivariate analysis controlling for Veau classification and syndromic diagnosis. Results: Sixty patients with a history of cleft palate were included. Forty-two (70%) patients had an associated cleft lip. Thirty-two (53.3%) patients had no history of fistula and 28 (46.7%) patients had undergone a fistula repair. CLEFT-Q Dental, Jaw, and Speech Function were all higher in patients without a history of a fistula repair; however, none of these differences were statistically significant. The COHIP-SF 19 Oral Health score demonstrated a significantly lower score in the fistula group, indicating poorer oral health ( P = .05). Conclusions: One would expect that successful repair of a fistula would result in improved function and patient satisfaction, but the consistent trend toward lower CLEFT-Q scores and significantly increased COHIP-SF 19 Oral Health scores in our study group suggests that residual effects linger and that the morbidity of a fistula may not be completely treated with a secondary correction.


2000 ◽  
Vol 9 (1) ◽  
pp. 52-63 ◽  
Author(s):  
Johan Herlitz ◽  
Kenneth Caidahl ◽  
Ingela Wiklund ◽  
Helén Sjöland ◽  
Björn Karlson ◽  
...  

2018 ◽  
Vol 89 (2) ◽  
pp. 187-205 ◽  
Author(s):  
Kyle S. Page ◽  
Bert Hayslip ◽  
Dee Wadsworth ◽  
Philip A. Allen

Persons with and without a family history of dementia report concerns for developing this syndrome; yet, less is known about the specific aspects of dementia that are feared. The Fear of Dementia (FOD) scale was created to assess these concerns. This study examined the psychometric properties of the FOD scale using a sample of middle-aged and older adults ( N = 734). We then explored the factor structure of the scale 2 years later using a smaller sample from the first study ( N = 226). Three factors emerged, highlighting several main areas of concern: Burden and Loss, Quality of Life, and Perceived Social and Cognitive Loss. Preliminary data suggest that the FOD scale is a reliable and valid instrument for assessing the multidimensional nature of the concern about developing dementia. Attention to what specifically is feared may help further our understanding of health behaviors, coping, and targeted supports.


2017 ◽  
pp. 118-122
Author(s):  
O.I. Zadnipryanaya ◽  

The objective: the study of clinical and psychological features of acne and quality of life in women with infertility. Patients and methods. 151 patients were included in the study: 111 with acne and infertility, 40 fertile women with acne entered the comparison group. An anamnesis, a dermatological and gynecological status, a hormonal background, an assessment of the psycho-emotional state and quality of life of patients (a Dermatological Index of Quality of Life – DIQL, the Hospital Scale of Anxiety and Depression – HADS), and the psychological and social effect of acne (APSEA questionnaire) were evaluated. Results. Infertile women with acne reliably recorded open and closed comedones, more often papules, stagnant spots, hyperpigmentation, enlarged pores, as well as atrophic scars were more often detected. They are characterized by a later menarche, an early onset of sexual activity. In 56.8% of infertile patients in the history of the disease, sexually transmitted diseases, abortions (8.1%), miscarriages and stagnant pregnancies (12.6%), ectopic pregnancy (4.5%). It was found that infertility lasts on average 4.9±3.6 years, with primary infertility diagnosed in 69.4% of cases. The endocrine nature of infertility was confirmed in 48 (43.2%) patients, tubo-peritoneal – in 63 (56.8%) of the women. It was found that the disease has a very strong effect on the quality of their life (13.3±6.2 points), causes a strong psychological and social effect (87.8±28.1 points), clinically expressed anxiety (11.8±4.4 points) and depressiveness (11.6±3.8 points). Conclusion. Acne in infertile patients in addition to clinical features is accompanied by significant violations of the psycho-emotional sphere and a decrease in the quality of life. Key words: women with acne and infertility, quality of life, psycho-emotional disorders, psychological and social effect of acne.


Author(s):  
Arjola Bano ◽  
Nicolas Rodondi ◽  
Jürg H. Beer ◽  
Giorgio Moschovitis ◽  
Richard Kobza ◽  
...  

Background Diabetes is a major risk factor for atrial fibrillation (AF). However, it remains unclear whether individual AF phenotype and related comorbidities differ between patients who have AF with and without diabetes. This study investigated the association of diabetes with AF phenotype and cardiac and neurological comorbidities in patients with documented AF. Methods and Results Participants in the multicenter Swiss‐AF (Swiss Atrial Fibrillation) study with data on diabetes and AF phenotype were eligible. Primary outcomes were parameters of AF phenotype, including AF type, AF symptoms, and quality of life (assessed by the European Quality of Life‐5 Dimensions Questionnaire [EQ‐5D]). Secondary outcomes were cardiac (ie, history of hypertension, myocardial infarction, and heart failure) and neurological (ie, history of stroke and cognitive impairment) comorbidities. The cross‐sectional association of diabetes with these outcomes was assessed using logistic and linear regression, adjusted for age, sex, and cardiovascular risk factors. We included 2411 patients with AF (27.4% women; median age, 73.6 years). Diabetes was not associated with nonparoxysmal AF (odds ratio [OR], 1.01; 95% CI, 0.81–1.27). Patients with diabetes less often perceived AF symptoms (OR, 0.74; 95% CI, 0.59–0.92) but had worse quality of life (β=−4.54; 95% CI, −6.40 to −2.68) than those without diabetes. Patients with diabetes were more likely to have cardiac (hypertension [OR, 3.04; 95% CI, 2.19–4.22], myocardial infarction [OR, 1.55; 95% CI, 1.18–2.03], heart failure [OR, 1.99; 95% CI, 1.57–2.51]) and neurological (stroke [OR, 1.39, 95% CI, 1.03–1.87], cognitive impairment [OR, 1.75, 95% CI, 1.39–2.21]) comorbidities. Conclusions Patients who have AF with diabetes less often perceive AF symptoms but have worse quality of life and more cardiac and neurological comorbidities than those without diabetes. This raises the question of whether patients with diabetes should be systematically screened for silent AF. Registration URL: https://www.clinicaltrials.gov ; Unique Identifier: NCT02105844.


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