Surface Energy-mediated Protein and Osteoblast Responses on Nanostructured Stiff Surfaces

2012 ◽  
Vol 1486 ◽  
Author(s):  
Lei Yang ◽  
Maswazi Sihlabela ◽  
Brian W. Sheldon ◽  
Thomas J. Webster

ABSTRACTNanostructured surfaces have demonstrated extraordinary capacity to influence protein adsorption and cellular responses, although the mechanisms behind such capacity are still not clear to date. In the present study, the role of surface energy associated with nanostructured stiff surfaces in modulating fibronectin and consequently osteoblast (OB, bone forming cells) responses was investigated. Nanocrystalline diamond (NCD) and submicron crystalline diamond (SMCD) films with controllable surface energy were prepared by microwave-enhanced plasma chemical vapor deposition (MPCVD) techniques. Fibronectin adsorption on the diamond films with varied surface energy values was measured via the enzyme-linked immunosorbent assay (ELISA) and the relationship between the surface energy and fibronectin adsorption was studied. OB aggregates (each containing 30∼50 cells) on the NCD with varied surface energy values were also studied. The results indicated that fibronectin adsorption on nanostructured surfaces was closely related to both surface energy and material microstructures, and osteoblast spreading and migration on stiff nanosurfaces are surface energy-driven processes.

2018 ◽  
Vol 15 (3) ◽  
pp. 389-398
Author(s):  
Ruchi Singh

Rural economies in developing countries are often characterized by credit constraints. Although few attempts have been made to understand the trends and patterns of male out-migration from Uttar Pradesh (UP), there is dearth of literature on the linkage between credit accessibility and male migration in rural Uttar Pradesh. The present study tries to fill this gap. The objective of this study is to assess the role of credit accessibility in determining rural male migration. A primary survey of 370 households was conducted in six villages of Jaunpur district in Uttar Pradesh. Simple statistical tools and a binary logistic regression model were used for analyzing the data. The result of the empirical analysis shows that various sources of credit and accessibility to them play a very important role in male migration in rural Uttar Pradesh. The study also found that the relationship between credit constraints and migration varies across various social groups in UP.


Shinku ◽  
1997 ◽  
Vol 40 (8) ◽  
pp. 660-663
Author(s):  
Hideo OKAYAMA ◽  
Tsukasa KUBO ◽  
Noritaka MOCHIZUKI ◽  
Akiyoshi NAGATA ◽  
Hiromu ISA

2009 ◽  
Vol 23 (09) ◽  
pp. 2159-2165 ◽  
Author(s):  
SUDIP ADHIKARI ◽  
MASAYOSHI UMENO

Nitrogen incorporated hydrogenated amorphous carbon (a-C:N:H) thin films have been deposited by microwave surface-wave plasma chemical vapor deposition on silicon and quartz substrates, using helium, methane and nitrogen ( N 2) as plasma source. The deposited a-C:N:H films were characterized by their optical, structural and electrical properties through UV/VIS/NIR spectroscopy, Raman spectroscopy, atomic force microscope and current-voltage characteristics. The optical band gap decreased gently from 3.0 eV to 2.5 eV with increasing N 2 concentration in the films. The a-C:N:H film shows significantly higher electrical conductivity compared to that of N 2-free a-C:H film.


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