Cytocompatibility of Carbon Nanofiber Materials for Neural Applications

2003 ◽  
Vol 774 ◽  
Author(s):  
Janice L. McKenzie ◽  
Michael C. Waid ◽  
Riyi Shi ◽  
Thomas J. Webster

AbstractSince the cytocompatibility of carbon nanofibers with respect to neural applications remains largely uninvestigated, the objective of the present in vitro study was to determine cytocompatibility properties of formulations containing carbon nanofibers. Carbon fiber substrates were prepared from four different types of carbon fibers, two with nanoscale diameters (nanophase, or less than or equal to 100 nm) and two with conventional diameters (or greater than 200 nm). Within these two categories, both a high and a low surface energy fiber were investigated and tested. Astrocytes (glial scar tissue-forming cells) and pheochromocytoma cells (PC-12; neuronal-like cells) were seeded separately onto the substrates. Results provided the first evidence that astrocytes preferentially adhered on the carbon fiber that had the largest diameter and the lowest surface energy. PC-12 cells exhibited the most neurites on the carbon fiber with nanodimensions and low surface energy. These results may indicate that PC-12 cells prefer nanoscale carbon fibers while astrocytes prefer conventional scale fibers. A composite was formed from poly-carbonate urethane and the 60 nm carbon fiber. Composite substrates were thus formed using different weight percentages of this fiber in the polymer matrix. Increased astrocyte adherence and PC-12 neurite density corresponded to decreasing amounts of the carbon nanofibers in the poly-carbonate urethane matrices. Controlling carbon fiber diameter may be an approach for increasing implant contact with neurons and decreasing scar tissue formation.

2003 ◽  
Vol 774 ◽  
Author(s):  
Janice L. McKenzie ◽  
Michael C. Waid ◽  
Riyi Shi ◽  
Thomas J. Webster

AbstractCarbon nanofibers possess excellent conductivity properties, which may be beneficial in the design of more effective neural prostheses, however, limited evidence on their cytocompatibility properties exists. The objective of the present in vitro study was to determine cytocompatibility and material properties of formulations containing carbon nanofibers to predict the gliotic scar tissue response. Poly-carbonate urethane was combined with carbon nanofibers in varying weight percentages to provide a supportive matrix with beneficial bulk electrical and mechanical properties. The substrates were tested for mechanical properties and conductivity. Astrocytes (glial scar tissue-forming cells) were seeded onto the substrates for adhesion. Results provided the first evidence that astrocytes preferentially adhered to the composite material that contained the lowest weight percentage of carbon nanofibers. Positive interactions with neurons, and, at the same time, limited astrocyte functions leading to decreased gliotic scar tissue formation are essential for increased neuronal implant efficacy.


2003 ◽  
Vol 774 ◽  
Author(s):  
Karen S. Ellison ◽  
Rachel L. Price ◽  
Karen M. Haberstroh ◽  
Thomas J. Webster

AbstractThe present study demonstrated for the first time desirable cytocompatibility properties of carbon nanofibers pertinent for bone prosthetic applications. Specifically, osteoblast (boneforming cells), fibroblast (cells contributing to callus formation and fibrous encapsulation events that result in implant loosening), chondrocyte (cartilage-forming cells), and smooth muscle cell (for comparison purposes) adhesion were determined on carbon nanofibers in the present in vitro study. Results provided evidence that nanometer dimension carbon fibers promoted select osteoblast adhesion, in contrast to the performance of conventional carbon fibers. Moreover, adhesion of other cells was not influenced by carbon fiber dimensions. To determine properties that selectively enhanced osteoblast adhesion, similar cell adhesion assays were performed on poly-lactic-co-glycolic (PLGA) casts of carbon fiber compacts previously tested. Compared to PLGA casts of conventional carbon fibers, results provided the first evidence of enhanced select osteoblast adhesion on PLGA casts of nanophase carbon fibers. The summation of these results demonstrate that due to a high degree of nanometer surface roughness, carbon fibers and PLGA with nanometer surface dimensions may be optimal materials to selectively increase osteoblast adhesion necessary for successful orthopedic implant applications.


Polymers ◽  
2018 ◽  
Vol 10 (12) ◽  
pp. 1319 ◽  
Author(s):  
Ran Li ◽  
Huiping Lin ◽  
Piao Lan ◽  
Jie Gao ◽  
Yan Huang ◽  
...  

Lightweight electromagnetic interference shielding cellulose foam/carbon fiber composites were prepared by blending cellulose foam solution with carbon fibers and then freeze drying. Two kinds of carbon fiber (diameter of 7 μm) with different lengths were used, short carbon fibers (SCF, L/D = 100) and long carbon fibers (LCF, L/D = 300). It was observed that SCFs and LCFs built efficient network structures during the foaming process. Furthermore, the foaming process significantly increased the specific electromagnetic interference shielding effectiveness from 10 to 60 dB. In addition, cellulose/carbon fiber composite foams possessed good mechanical properties and low thermal conductivity of 0.021–0.046 W/(m·K).


2011 ◽  
Vol 87 ◽  
pp. 49-54 ◽  
Author(s):  
Hai Chen Lin

This thesis use AOC15/50 blade as baseline model which is a composite wind turbine blade made of glass/epoxy for a horizontal axis wind turbine. A finite element modeling of composite wind turbine blade was created using the SHELL element of ANSYS. Then we study how to use the carbon fiber material replaces the glass fiber to make the hybrid blade, and find a suitable layup to improve the performance of the blade. The hybrid blade was made through introducing carbon fibers. Different models, with introducing different number of carbon fibers, 75% carbon fibers replace unidirectional glass fibers in spar cap of blade model which can achieve best structure performance. The wind turbine blades are often fabricated by hand using multiple of glass fiber-reinforced polyester resin or glass fiber-reinforced epoxy resin. As commercial machines get bigger, this could not to meet the demands. The advantages of carbon fiber composite materials are used by blade producer. Studies show that carbon fiber has high strength-to-weight ratio and resistance fatigue properties. Carbon fiber is mixed with epoxy resin to make into carbon fiber-reinforced polymer. Carbon fiber-reinforced polymer is the one of best blade materials for resistance bad weather. The stiffness of carbon fiber composite is 2 or 3 times higher than glass fiber composite [1], but the cost of carbon fiber composite is 10 times higher than glass fiber composite. If all of wind turbine blades are made of carbon fiber composite, it will be very expensive. Therefore carbon/glass fiber hybrid composite blade has become a research emphasis in the field of blade materials. This paper gives an example of finite element modeling composite wind turbine blade in ANSYS by means of the medium-length blade of AOC 15/50 horizontal axis wind turbine. This model can be directly used in dynamics analysis and does not need to be imported from the CAD software into finite element program. This finite element modeling of composite wind turbine blade was created using the SHELL element of ANSYS. Then we study how to use the carbon fiber material replaces the glass fiber to make the hybrid blade, and find a suitable lay-up to improve the performance of the blade.


2011 ◽  
Vol 57 (4) ◽  
pp. 97-106 ◽  
Author(s):  
Jittiwat NITHIKARNJANATHARN ◽  
Hisai UEDA ◽  
Shuichi TANOUE ◽  
Hideyuki UEMATSU ◽  
Yoshiyuki IEMOTO

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
John Wiselin ◽  
Sreeja Balakrishnapillai Suseela ◽  
Bycil Viswambaran Jalaja ◽  
Sherin Dhas Sahayadas Padma Ramani ◽  
Rajesh Prasad ◽  
...  

This paper investigates the possibilities of using carbon fiber as an inductor material by analyzing its inductive properties. Various shapes such as rectangular, spiral, helical, and cylindrical line structures have been simulated under various constraints using simulation software. Hardware implementations were also tested and both simulation and hardware results show that carbon fibers have the potential to replace copper inductor lines. The implemented spiral inductor produced a quality factor of 40 while producing an inductance of 4 nH at 1.2 GHz frequency.


2011 ◽  
Vol 239-242 ◽  
pp. 141-144
Author(s):  
Jia Horng Lin ◽  
Jin Mao Chen ◽  
Ching Wen Lin ◽  
Wen Hao Hsing ◽  
Yu Chia Hsu ◽  
...  

In this study, carbon fibers (CF) were braided with polypropylene (PP) fibers on a 16-spindle braid machine, forming the PP/ CF composite braids. The composite braids with different levels of strength could be obtained by changing the speed of the yarn turntable and volume gauze. The composite braids with optimum tensile strength then received the thermal treatment, which melted the PP fibers to wrap the CF more tightly, stabilizing the structure of the composite braids. According to CNS 11623 (Tensile Properties of Geogrids by the Single), the composite braids were thermal-treated at 170 °C, 180 °C and 190 °C for1 min, 2 min and 3 min, determing the influence of thermal temperature and duration on the tensile strength of PP/ CF composite braids.


2017 ◽  
Vol 19 (8) ◽  
pp. 1794-1827 ◽  
Author(s):  
Wei Fang ◽  
Sheng Yang ◽  
Xi-Luan Wang ◽  
Tong-Qi Yuan ◽  
Run-Cang Sun

This review details recent progress in the conversion of technical lignins to multi-functional, high-value, and promising carbon fiber materials, and discusses their applications.


2019 ◽  
Vol 86 (10) ◽  
Author(s):  
Xuemin Wang ◽  
Tingge Xu ◽  
Rui Zhang ◽  
Monica Jung de Andrade ◽  
Pruthul Kokkada ◽  
...  

Polymer matrix composites have high strengths in tension. However, their compressive strengths are much lower than their tensile strengths due to their weak fiber/matrix interfacial shear strengths. We recently developed a new approach to fabricate composites by overwrapping individual carbon fibers or fiber tows with a carbon nanotube sheet and subsequently impregnate them into a matrix to enhance the interfacial shear strengths without degrading the tensile strengths of the carbon fibers. In this study, a theoretical analysis is conducted to identify the appropriate thickness of the nanocomposite interphase region formed by carbon nanotubes embedded in a matrix. Fibers are modeled as an anisotropic elastic material, and the nanocomposite interphase region and the matrix are considered as isotropic. A microbuckling problem is solved for the unidirectional composite under compression. The analytical solution is compared with finite element simulations for verification. It is determined that the critical load at the onset of buckling is lower in an anisotropic carbon fiber composite than in an isotropic fibfer composite due to lower transverse properties in the fibers. An optimal thickness for nanocomposite interphase region is determined, and this finding provides a guidance for the manufacture of composites using aligned carbon nanotubes as fillers in the nanocomposite interphase region.


2021 ◽  
pp. 002199832110154
Author(s):  
Xiaojian Cao ◽  
Jialiang Li

Carbon fibers were surface treated with supercritical water/nitrate system to improve the interfacial adhesion of the carbon fiber/epoxy composite. The surface chemistry analysis showed that oxygen functional groups on the surface of the carbon fibers increased after treatment, which were mainly carbonyl and carboxyl groups. The surface microstructure observation indicated that the treatment obviously increased the surface roughness of the carbon fibers. Surface energy of the treated carbon fibers also increased. The increased functional groups, surface roughness and surface energy were beneficial to enhance the interfacial adhesion of the carbon fiber/epoxy composite. Compared with the untreated carbon fibers, the strength loss of the treated carbon fibers was less than 3% and the other mechanical properties were almost unchanged. The caclulated interfacial fracture energy and the interfacial shear strength of the treated carbon fiber/epoxy composite were enhanced by 19% and 29%, respectively, compared with the untreated carbon fiber/epoxy composite. In summary, supercritical water/nitrate treatment is a potential method for changing the inert surface of carbon fibers to improve the interfacial adhesion between carbon fibers and matrix.


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